Wheat Germ

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34 Diseases Researched for Wheat Germ
NameACCKFocus
Colorectal Cancer321Locked
Arthritis: Rheumatoid110Locked
Chemotherapy-Induced Toxicity110Locked
Giardiasis110Locked
Neutropenia: Chemotherapy Induced110Locked
Cancers15Locked
Cancers: All44Locked
Colon Cancer34Locked
Oxidative Stress23Locked
Pancreatic Cancer33Locked
Acute Myeloid Leukemia12Locked
Bladder Outlet Obstruction12Locked
Breast Cancer12Locked
Chemotherapy-Induced Toxicity: Cyclophosphamide12Locked
Gastrointestinal Inflammation12Locked
High Fat Diet12Locked
High Sugar Diet12Locked
Lipid Peroxidation12Locked
Myocardial Infarction12Locked
Prostatic Hyperplasia: Benign12Locked
Testicular Injury: Chemical/Metal Induced12Locked
Acute T cell Leukemias11Locked
Arthritis11Locked
Autoimmune Diseases11Locked
Cachexia11Locked
Cervical Cancer11Locked
Inflammation11Locked
Lipopolysaccharide-Induced Toxicity11Locked
Lymphoma11Locked
Mastalgia11Locked
Melanoma11Locked
Premenstrual syndrome11Locked
Salmonella Infections11Locked
Staphylococcus aureus infection11Locked
28 Pharmacological Actions Researched for Wheat Germ
NameACCKFocus
Apoptotic914Locked
Antiproliferative 711Locked
Antiprotozoal Agents110Locked
Drug synergy110Locked
Antioxidants58Locked
Antineoplastic Agents37Locked
Anticarcinogenic Agents46Locked
Anti-Inflammatory Agents45Locked
Chemopreventive34Locked
Interleukin-6 Downregulation23Locked
Cell cycle arrest22Locked
Cyclooxygenase 2 Inhibitors22Locked
Gastrointestinal Agents12Locked
Immunostimulatory12Locked
Interleukin-1 beta downregulation12Locked
Neocardiogenic 12Locked
Analgesics11Locked
Anti-Bacterial Agents11Locked
Anti-metastatic11Locked
Chemotherapeutic11Locked
Cyclooxygenase 1 Inhibitor11Locked
Enzyme Inhibitors11Locked
Heme oxygenase-1 up-regulation11Locked
Immunomodulatory11Locked
Interleukin-10 upregulation11Locked
Interleukin-12 downregulation11Locked
Paraptosis11Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor11Locked
Related Topics

Wheat Germ is a Sub of the following Topic

View the Evidence:
31 Abstracts with Wheat Germ Research

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A fermented wheat germ extract significantly improves patients with severe rheumatoid arthritis.May 01, 2006

Pubmed Data : Clin Exp Rheumatol. 2006 May-Jun;24(3):325-8. PMID: 18771352
Article Published Date : May 01, 2006
Study Type : Human Study
Additional Links
Substances : Wheat Germ
Diseases : Arthritis: Rheumatoid
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A fermented wheat germ extract significantly improves the outcome of patients with colorectal cancer.Sep 11, 2005

Pubmed Data : Orv Hetil. 2005 Sep 11;146(37):1925-31. PMID: 16255377
Article Published Date : Sep 11, 2005
Study Type : Human Study
Additional Links
Substances : Wheat Germ
Diseases : Colorectal Cancer
Pharmacological Actions : Drug synergy
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Fermented wheat germ extract reduces chemotherapy-induced febrile neutropenia in pediatric patients.Oct 01, 2004

Pubmed Data : J Pediatr Hematol Oncol. 2004 Oct;26(10):631-5. PMID: 15454833
Article Published Date : Oct 01, 2004
Study Type : Human Study
Additional Links
Substances : Wheat Germ
Diseases : Chemotherapy-Induced Toxicity, Neutropenia: Chemotherapy Induced
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Fermented wheat germ has therapeutic value in the treatment of colorectal cancer.Mar 01, 2000

Pubmed Data : Hepatogastroenterology. 2000 Mar-Apr;47(32):393-5. PMID: 10791198
Article Published Date : Mar 01, 2000
Study Type : Human Study
Additional Links
Substances : Fermented Foods and Beverages, Wheat Germ
Diseases : Colorectal Cancer
Additional Keywords : Lectins, Plant Extracts
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Wheat germ supplementation may positively influence the course of treatment for giardiasis.Jun 18, 2008

Pubmed Data : Cancer Lett. 2008 Jun 18;264(2):229-40. Epub 2008 Mar 14. PMID: 11791961
Article Published Date : Jun 18, 2008
Study Type : Human Study
Additional Links
Substances : Wheat Germ
Diseases : Giardiasis
Pharmacological Actions : Antiprotozoal Agents
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Promising cytotoxic activity profile of fermented wheat germ extract in human cancer cell lines.Apr 15, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Exp Clin Cancer Res. 2011 Apr 16 ;30:42. Epub 2011 Apr 16. PMID: 21496306
Article Published Date : Apr 15, 2011
Study Type : Human In Vitro
Additional Links
Substances : Fermented Foods and Beverages, Wheat Germ
Diseases : Cancers
Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic
Additional Keywords : Chemothapeutic Synergy: 5-flourouracil, Chemotherapeutic Synergy: Oxaliplatin, Plant Extracts
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A proprietary blend of herbs suppresses urinary oxidative stress in a rabbit model of partial bladder outlet obstruction and in patients with benign prostatic hyperplasia.Feb 01, 2010

Pubmed Data : Phytother Res. 2010 Feb;24(2):301-3. PMID: 19585469
Article Published Date : Feb 01, 2010
Study Type : Animal Study
Additional Links
Substances : Aspen, Horsetail, Pipsisssewa, Pulsatilla pratensis, Wheat Germ
Diseases : Bladder Outlet Obstruction, Oxidative Stress, Prostatic Hyperplasia: Benign
Pharmacological Actions : Antioxidants
Additional Keywords : Plant Extracts
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Avemar and Echinacea extracts can effectively induce mobilization and homing of CD34+ stem cells to the myocardial tissue and thus may help in stem cell-based regeneration.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Stem Cell Res Ther. 2015 ;6(1):172. Epub 2015 Sep 14. PMID: 26369808
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Echinacea, Wheat Germ
Diseases : Myocardial Infarction
Pharmacological Actions : Neocardiogenic
Additional Keywords : myocardial regeneration, Plant Extracts
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Dietary supplementation with purified wheat germ glycoprotein improve immunostimulatory activity in cyclophosphamide induced Balb/c mice.Oct 14, 2018

Pubmed Data : Int J Biol Macromol. 2018 Oct 15 ;118(Pt A):1267-1275. Epub 2018 Jul 4. PMID: 29981325
Article Published Date : Oct 14, 2018
Study Type : Animal Study
Additional Links
Substances : Wheat Germ
Diseases : Chemotherapy-Induced Toxicity: Cyclophosphamide
Pharmacological Actions : Immunostimulatory
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The preventive role of wheat germ oil against sertraline-induced testicular damage in male albino rats.Oct 31, 2019

Pubmed Data : Andrologia. 2019 Nov ;51(10):e13369. Epub 2019 Aug 16. PMID: 31418462
Article Published Date : Oct 31, 2019
Study Type : Animal Study
Additional Links
Substances : Wheat Germ
Diseases : Lipid Peroxidation, Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Antioxidants
Problem Substances : Sertraline
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The results suggested that the effect of flavonoids on inducing peroxidase might be one of the chemical prevention mechanisms on mammary tumors.Jun 30, 2001

Pubmed Data : Wei Sheng Yan Jiu. 2001 Jul ;30(4):215-7. PMID: 12561518
Article Published Date : Jun 30, 2001
Study Type : Animal Study
Additional Links
Substances : Flavonoids, Wheat Germ
Diseases : Breast Cancer
Pharmacological Actions : Anticarcinogenic Agents, Antioxidants, Chemopreventive
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Wheat germ agglutinin as a potential therapeutic agent for leukemia.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Oncol. 2019 ;9:100. Epub 2019 Feb 21. PMID: 30847305
Article Published Date : Dec 31, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Wheat Germ
Diseases : Acute Myeloid Leukemia
Pharmacological Actions : Apoptotic
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Wheat germ extract inhibits experimental colon carcinogenesis.Sep 30, 2001

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Carcinogenesis. 2001 Oct ;22(10):1649-52. PMID: 11577004
Article Published Date : Sep 30, 2001
Study Type : Animal Study
Additional Links
Substances : Fermented Foods and Beverages, Wheat Germ
Diseases : Colon Cancer
Pharmacological Actions : Anticarcinogenic Agents
Additional Keywords : Lectins, Phytotherapy, Plant Extracts
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Wheat germ supplementation increases Lactobacillaceae and promotes an anti-inflammatory gut milieu.Jun 30, 2019

Pubmed Data : J Nutr. 2019 Jul 1 ;149(7):1107-1115. PMID: 31162575
Article Published Date : Jun 30, 2019
Study Type : Animal Study
Additional Links
Substances : Wheat Germ
Diseases : Gastrointestinal Inflammation, High Fat Diet, High Sugar Diet
Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation
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A fermented wheat germ extract attenuates the growth of human lymphoma cells through induction of programmed cell death. Mar 01, 2009

Pubmed Data : Oncol Rep. 2009 Mar;21(3):787-91. PMID: 19212640
Article Published Date : Mar 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Fermented Foods and Beverages, Wheat Germ
Diseases : Lymphoma
Pharmacological Actions : Apoptotic
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A review of effective medicinal plants in the treatment of the cyclic mastalgia.Aug 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Pharmacopuncture. 2019 Sep ;22(3):131-139. Epub 2019 Sep 30. PMID: 31673442
Article Published Date : Aug 31, 2019
Study Type : Review
Additional Links
Substances : Chaste Tree (Chasteberry), Curcumin, Ginkgo biloba, Nigella sativa (aka Black Seed), St. Johns Wort, Sweet Orange, Wheat Germ
Diseases : Mastalgia
Pharmacological Actions : Analgesics, Anti-Inflammatory Agents, Antioxidants
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A review of the effects of adjuvant fermented wheat germ extract on cancer cell lines.Oct 18, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2018 Oct 19 ;10(10). Epub 2018 Oct 19. PMID: 30347664
Article Published Date : Oct 18, 2018
Study Type : Review
Additional Links
Substances : Fermented Foods and Beverages, Wheat Germ
Diseases : Cancers: All
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
Additional Keywords : Plant Extracts
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Antimicrobial activities of 1,4-benzoquinones and wheat germ extract.Jul 31, 2010

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Microbiol Biotechnol. 2010 Aug ;20(8):1204-9. PMID: 20798583
Article Published Date : Jul 31, 2010
Study Type : In Vitro Study
Additional Links
Substances : Wheat Germ
Diseases : Salmonella Infections, Staphylococcus aureus infection
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Plant Extracts
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Available data so far, justify the use of Fermented wheat germ extract as a non-prescription medical nutriment for cancer patients.Sep 04, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr J. 2011 Sep 5 ;10:89. Epub 2011 Sep 5. PMID: 21892933
Article Published Date : Sep 04, 2011
Study Type : Review
Additional Links
Substances : Fermented Foods and Beverages, Wheat Germ
Diseases : Cancers: All, Colon Cancer, Colorectal Cancer, Melanoma
Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic, Chemopreventive, Chemotherapeutic
Additional Keywords : Plant Extracts
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Avemar (wheat germ extract) in cancer prevention and treatment.Dec 31, 2008

Pubmed Data : Nutr Cancer. 2009 ;61(6):891-9. PMID: 20155632
Article Published Date : Dec 31, 2008
Study Type : Review
Additional Links
Substances : Wheat Germ
Diseases : Cachexia, Cancers: All
Pharmacological Actions : Anti-metastatic, Anticarcinogenic Agents, Antiproliferative , Apoptotic
Additional Keywords : Plant Extracts
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Citric acid treatment enhanced the anti-inflammatory activity of wheat germ extract.Jul 09, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2017 Jul 10 ;9(7). Epub 2017 Jul 10. PMID: 28698513
Article Published Date : Jul 09, 2017
Study Type : In Vitro Study
Additional Links
Substances : Citric Acid , Fermented Foods and Beverages, Wheat Germ
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Heme oxygenase-1 up-regulation, Interleukin-10 upregulation, Interleukin-12 downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
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Effect of fermented wheat germ extract with lactobacillus plantarum dy-1 on HT-29 cell proliferation and apoptosis.Mar 10, 2015

Pubmed Data : J Agric Food Chem. 2015 Mar 11 ;63(9):2449-57. Epub 2015 Mar 2. PMID: 25658135
Article Published Date : Mar 10, 2015
Study Type : In Vitro Study
Additional Links
Substances : Fermented Foods and Beverages, Lactobacillus plantarum, Wheat Germ
Diseases : Colon Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
Additional Keywords : Plant Extracts
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Fermented wheat germ extract (Avemar) in the treatment of cancer and autoimmune diseases.May 31, 2005

Pubmed Data : Ann N Y Acad Sci. 2005 Jun ;1051:529-42. PMID: 16126993
Article Published Date : May 31, 2005
Study Type : Review
Additional Links
Substances : Fermented Foods and Beverages, Wheat Germ
Diseases : Autoimmune Diseases, Cancers: All
Pharmacological Actions : Anticarcinogenic Agents, Chemopreventive, Immunomodulatory
Additional Keywords : Plant Extracts
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Fermented wheat germ extract (avemar) inhibits adjuvant arthritis.Aug 31, 2007

Pubmed Data : Ann N Y Acad Sci. 2007 Sep ;1110:348-61. PMID: 17911450
Article Published Date : Aug 31, 2007
Study Type : In Vitro Study
Additional Links
Substances : Fermented Foods and Beverages, Wheat Germ
Diseases : Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 1 Inhibitor, Cyclooxygenase 2 Inhibitors
Additional Keywords : Plant Extracts
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Fermented wheat germ extract inhibits glycolysis/pentose cycle enzymes and induces apoptosis in Jurkat T-cell leukemia tumor cells.Nov 28, 2002

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Biol Chem. 2002 Nov 29 ;277(48):46408-14. Epub 2002 Sep 25. PMID: 12351627
Article Published Date : Nov 28, 2002
Study Type : In Vitro Study
Additional Links
Substances : Fermented Foods and Beverages, Wheat Germ
Diseases : Acute T cell Leukemias
Pharmacological Actions : Apoptotic, Enzyme Inhibitors
Additional Keywords : Plant Extracts
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Genistein and a fermented wheat germ extract (Avemar) may inhibit pancreatic cancer cell growth. Jan 01, 2002

Pubmed Data : Pancreas. 2002 Jan;24(1):26-33. PMID: 11741179
Article Published Date : Jan 01, 2002
Study Type : Commentary
Additional Links
Substances : Wheat Germ
Diseases : Pancreatic Cancer
Additional Keywords : Cancer as a Glucose-Based Disease
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This research demonstrated efficacy and safety of Iranian herbal medicines in alleviating PMS.Feb 28, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Avicenna J Phytomed. 2018 Mar-Apr;8(2):96-113. PMID: 29632841
Article Published Date : Feb 28, 2018
Study Type : Review
Additional Links
Substances : Chamomile, Chaste Tree (Chasteberry), Curcumin, Fennel, Flaxseed, Ginger, Lemon Balm, Orange, Saffron, St. Johns Wort, Valerian, Wheat Germ, Zataria multiflora
Diseases : Premenstrual syndrome
Additional Keywords : Traditional Iranian Medicine
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Wheat germ agglutinin-induced paraptosis-like cell death and protective autophagy is mediated by autophagy-linked FYVE inhibition.Oct 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2017 Oct 31 ;8(53):91209-91222. Epub 2017 Aug 24. PMID: 29207637
Article Published Date : Oct 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Wheat Germ
Diseases : Cervical Cancer
Pharmacological Actions : Apoptotic, Paraptosis
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Wheat germ extract decreases glucose uptake and RNA ribose formation but increases fatty acid synthesis in MIA pancreatic adenocarcinoma cells.Jul 31, 2001

Pubmed Data : Pancreas. 2001 Aug ;23(2):141-7. PMID: 11484916
Article Published Date : Jul 31, 2001
Study Type : In Vitro Study
Additional Links
Substances : Wheat Germ
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative
Additional Keywords : Plant Extracts
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Wheat germ protein could exert an effective antioxidant action by across the intestinal epithelium.Jul 31, 2019

Pubmed Data : J Food Sci. 2019 Aug ;84(8):2139-2146. Epub 2019 Jul 17. PMID: 31313302
Article Published Date : Jul 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Wheat Germ
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants
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Wheatgerm agglutinin (WGA) is cytotoxic to pancreatic cancer cells.Aug 01, 1999

Pubmed Data : Br J Cancer. 1999 Aug;80(11):1754-62. PMID: 10468292
Article Published Date : Aug 01, 1999
Study Type : In Vitro Study
Additional Links
Substances : Wheat Germ
Diseases : Pancreatic Cancer
Pharmacological Actions : Antineoplastic Agents, Antiproliferative

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