Wheat Germ

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11 Diseases Researched for Wheat Germ
NameACCKFocus
Colorectal Cancer220Locked
Arthritis: Rheumatoid110Locked
Chemotherapy-Induced Toxicity110Locked
Giardiasis110Locked
Neutropenia: Chemotherapy Induced110Locked
Bladder Outlet Obstruction12Locked
Myocardial Infarction12Locked
Oxidative Stress12Locked
Pancreatic Cancer22Locked
Prostatic Hyperplasia: Benign12Locked
Lymphoma11Locked
7 Pharmacological Actions Researched for Wheat Germ
NameACCKFocus
Antiprotozoal Agents110Locked
Drug synergy110Locked
Antioxidants12Locked
Neocardiogenic 12Locked
Antineoplastic Agents11Locked
Antiproliferative 11Locked
Apoptotic11Locked
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Wheat Germ is a Sub of the following Topic

View the Evidence:
31 Abstracts with Wheat Germ Research

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A fermented wheat germ extract significantly improves patients with severe rheumatoid arthritis.May 01, 2006

Pubmed Data : Clin Exp Rheumatol. 2006 May-Jun;24(3):325-8. PMID: 18771352
Article Published Date : May 01, 2006
Study Type : Human Study
Additional Links
Substances : Wheat Germ
Diseases : Arthritis: Rheumatoid
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A fermented wheat germ extract significantly improves the outcome of patients with colorectal cancer.Sep 11, 2005

Pubmed Data : Orv Hetil. 2005 Sep 11;146(37):1925-31. PMID: 16255377
Article Published Date : Sep 11, 2005
Study Type : Human Study
Additional Links
Substances : Wheat Germ
Diseases : Colorectal Cancer
Pharmacological Actions : Drug synergy
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Fermented wheat germ extract reduces chemotherapy-induced febrile neutropenia in pediatric patients.Oct 01, 2004

Pubmed Data : J Pediatr Hematol Oncol. 2004 Oct;26(10):631-5. PMID: 15454833
Article Published Date : Oct 01, 2004
Study Type : Human Study
Additional Links
Substances : Wheat Germ
Diseases : Chemotherapy-Induced Toxicity, Neutropenia: Chemotherapy Induced
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Fermented wheat germ has therapeutic value in the treatment of colorectal cancer.Mar 01, 2000

Pubmed Data : Hepatogastroenterology. 2000 Mar-Apr;47(32):393-5. PMID: 10791198
Article Published Date : Mar 01, 2000
Study Type : Human Study
Additional Links
Substances : Fermented Foods and Beverages, Wheat Germ
Diseases : Colorectal Cancer
Additional Keywords : Lectins, Plant Extracts
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Wheat germ supplementation may positively influence the course of treatment for giardiasis.Jun 18, 2008

Pubmed Data : Cancer Lett. 2008 Jun 18;264(2):229-40. Epub 2008 Mar 14. PMID: 11791961
Article Published Date : Jun 18, 2008
Study Type : Human Study
Additional Links
Substances : Wheat Germ
Diseases : Giardiasis
Pharmacological Actions : Antiprotozoal Agents
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Promising cytotoxic activity profile of fermented wheat germ extract in human cancer cell lines.Apr 15, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Exp Clin Cancer Res. 2011 Apr 16 ;30:42. Epub 2011 Apr 16. PMID: 21496306
Article Published Date : Apr 15, 2011
Study Type : Human In Vitro
Additional Links
Substances : Fermented Foods and Beverages, Wheat Germ
Diseases : Cancers
Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic
Additional Keywords : Chemothapeutic Synergy: 5-flourouracil, Chemotherapeutic Synergy: Oxaliplatin, Plant Extracts
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A proprietary blend of herbs suppresses urinary oxidative stress in a rabbit model of partial bladder outlet obstruction and in patients with benign prostatic hyperplasia.Feb 01, 2010

Pubmed Data : Phytother Res. 2010 Feb;24(2):301-3. PMID: 19585469
Article Published Date : Feb 01, 2010
Study Type : Animal Study
Additional Links
Substances : Aspen, Horsetail, Pipsisssewa, Pulsatilla pratensis, Wheat Germ
Diseases : Bladder Outlet Obstruction, Oxidative Stress, Prostatic Hyperplasia: Benign
Pharmacological Actions : Antioxidants
Additional Keywords : Plant Extracts
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Avemar and Echinacea extracts can effectively induce mobilization and homing of CD34+ stem cells to the myocardial tissue and thus may help in stem cell-based regeneration.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Stem Cell Res Ther. 2015 ;6(1):172. Epub 2015 Sep 14. PMID: 26369808
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Echinacea, Wheat Germ
Diseases : Myocardial Infarction
Pharmacological Actions : Neocardiogenic
Additional Keywords : Myocardial Regeneration, Plant Extracts
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Dietary supplementation with purified wheat germ glycoprotein improve immunostimulatory activity in cyclophosphamide induced Balb/c mice.Oct 14, 2018

Pubmed Data : Int J Biol Macromol. 2018 Oct 15 ;118(Pt A):1267-1275. Epub 2018 Jul 4. PMID: 29981325
Article Published Date : Oct 14, 2018
Study Type : Animal Study
Additional Links
Substances : Wheat Germ
Diseases : Chemotherapy-Induced Toxicity: Cyclophosphamide
Pharmacological Actions : Immunostimulatory
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The preventive role of wheat germ oil against sertraline-induced testicular damage in male albino rats.Oct 31, 2019

Pubmed Data : Andrologia. 2019 Nov ;51(10):e13369. Epub 2019 Aug 16. PMID: 31418462
Article Published Date : Oct 31, 2019
Study Type : Animal Study
Additional Links
Substances : Wheat Germ
Diseases : Lipid Peroxidation, Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Antioxidants
Problem Substances : Sertraline
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The results suggested that the effect of flavonoids on inducing peroxidase might be one of the chemical prevention mechanisms on mammary tumors.Jun 30, 2001

Pubmed Data : Wei Sheng Yan Jiu. 2001 Jul ;30(4):215-7. PMID: 12561518
Article Published Date : Jun 30, 2001
Study Type : Animal Study
Additional Links
Substances : Flavonoids, Wheat Germ
Diseases : Breast Cancer
Pharmacological Actions : Anticarcinogenic Agents, Antioxidants, Chemopreventive
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Wheat germ agglutinin as a potential therapeutic agent for leukemia.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Oncol. 2019 ;9:100. Epub 2019 Feb 21. PMID: 30847305
Article Published Date : Dec 31, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Wheat Germ
Diseases : Acute Myeloid Leukemia
Pharmacological Actions : Apoptotic
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Wheat germ extract inhibits experimental colon carcinogenesis.Sep 30, 2001

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Carcinogenesis. 2001 Oct ;22(10):1649-52. PMID: 11577004
Article Published Date : Sep 30, 2001
Study Type : Animal Study
Additional Links
Substances : Fermented Foods and Beverages, Wheat Germ
Diseases : Colon Cancer
Pharmacological Actions : Anticarcinogenic Agents
Additional Keywords : Lectins, Phytotherapy, Plant Extracts
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Wheat germ supplementation increases Lactobacillaceae and promotes an anti-inflammatory gut milieu.Jun 30, 2019

Pubmed Data : J Nutr. 2019 Jul 1 ;149(7):1107-1115. PMID: 31162575
Article Published Date : Jun 30, 2019
Study Type : Animal Study
Additional Links
Substances : Wheat Germ
Diseases : Gastrointestinal Inflammation, High Fat Diet, High Sugar Diet
Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation
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A fermented wheat germ extract attenuates the growth of human lymphoma cells through induction of programmed cell death. Mar 01, 2009

Pubmed Data : Oncol Rep. 2009 Mar;21(3):787-91. PMID: 19212640
Article Published Date : Mar 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Fermented Foods and Beverages, Wheat Germ
Diseases : Lymphoma
Pharmacological Actions : Apoptotic
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A review of effective medicinal plants in the treatment of the cyclic mastalgia.Aug 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Pharmacopuncture. 2019 Sep ;22(3):131-139. Epub 2019 Sep 30. PMID: 31673442
Article Published Date : Aug 31, 2019
Study Type : Review
Additional Links
Substances : Chaste Tree (Chasteberry), Curcumin, Ginkgo biloba, Nigella sativa (aka Black Seed), St. Johns Wort, Sweet Orange, Wheat Germ
Diseases : Mastalgia
Pharmacological Actions : Analgesics, Anti-Inflammatory Agents, Antioxidants
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A review of the effects of adjuvant fermented wheat germ extract on cancer cell lines.Oct 18, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2018 Oct 19 ;10(10). Epub 2018 Oct 19. PMID: 30347664
Article Published Date : Oct 18, 2018
Study Type : Review
Additional Links
Substances : Fermented Foods and Beverages, Wheat Germ
Diseases : Cancers: All
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
Additional Keywords : Plant Extracts
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Antimicrobial activities of 1,4-benzoquinones and wheat germ extract.Jul 31, 2010

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Microbiol Biotechnol. 2010 Aug ;20(8):1204-9. PMID: 20798583
Article Published Date : Jul 31, 2010
Study Type : In Vitro Study
Additional Links
Substances : Wheat Germ
Diseases : Salmonella Infections, Staphylococcus aureus infection
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Plant Extracts
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Available data so far, justify the use of Fermented wheat germ extract as a non-prescription medical nutriment for cancer patients.Sep 04, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr J. 2011 Sep 5 ;10:89. Epub 2011 Sep 5. PMID: 21892933
Article Published Date : Sep 04, 2011
Study Type : Review
Additional Links
Substances : Fermented Foods and Beverages, Wheat Germ
Diseases : Cancers: All, Colon Cancer, Colorectal Cancer, Melanoma
Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic, Chemopreventive, Chemotherapeutic
Additional Keywords : Plant Extracts
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Avemar (wheat germ extract) in cancer prevention and treatment.Dec 31, 2008

Pubmed Data : Nutr Cancer. 2009 ;61(6):891-9. PMID: 20155632
Article Published Date : Dec 31, 2008
Study Type : Review
Additional Links
Substances : Wheat Germ
Diseases : Cachexia, Cancers: All
Pharmacological Actions : Anti-metastatic, Anticarcinogenic Agents, Antiproliferative , Apoptotic
Additional Keywords : Plant Extracts
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Citric acid treatment enhanced the anti-inflammatory activity of wheat germ extract.Jul 09, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2017 Jul 10 ;9(7). Epub 2017 Jul 10. PMID: 28698513
Article Published Date : Jul 09, 2017
Study Type : In Vitro Study
Additional Links
Substances : Citric Acid , Fermented Foods and Beverages, Wheat Germ
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Heme oxygenase-1 up-regulation, Interleukin-10 upregulation, Interleukin-12 downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
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Effect of fermented wheat germ extract with lactobacillus plantarum dy-1 on HT-29 cell proliferation and apoptosis.Mar 10, 2015

Pubmed Data : J Agric Food Chem. 2015 Mar 11 ;63(9):2449-57. Epub 2015 Mar 2. PMID: 25658135
Article Published Date : Mar 10, 2015
Study Type : In Vitro Study
Additional Links
Substances : Fermented Foods and Beverages, Lactobacillus plantarum, Wheat Germ
Diseases : Colon Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
Additional Keywords : Plant Extracts
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Fermented wheat germ extract (Avemar) in the treatment of cancer and autoimmune diseases.May 31, 2005

Pubmed Data : Ann N Y Acad Sci. 2005 Jun ;1051:529-42. PMID: 16126993
Article Published Date : May 31, 2005
Study Type : Review
Additional Links
Substances : Fermented Foods and Beverages, Wheat Germ
Diseases : Autoimmune Diseases, Cancers: All
Pharmacological Actions : Anticarcinogenic Agents, Chemopreventive, Immunomodulatory
Additional Keywords : Plant Extracts
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Fermented wheat germ extract (avemar) inhibits adjuvant arthritis.Aug 31, 2007

Pubmed Data : Ann N Y Acad Sci. 2007 Sep ;1110:348-61. PMID: 17911450
Article Published Date : Aug 31, 2007
Study Type : In Vitro Study
Additional Links
Substances : Fermented Foods and Beverages, Wheat Germ
Diseases : Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 1 Inhibitor, Cyclooxygenase 2 Inhibitors
Additional Keywords : Plant Extracts
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Fermented wheat germ extract inhibits glycolysis/pentose cycle enzymes and induces apoptosis in Jurkat T-cell leukemia tumor cells.Nov 28, 2002

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Biol Chem. 2002 Nov 29 ;277(48):46408-14. Epub 2002 Sep 25. PMID: 12351627
Article Published Date : Nov 28, 2002
Study Type : In Vitro Study
Additional Links
Substances : Fermented Foods and Beverages, Wheat Germ
Diseases : Acute T cell Leukemias
Pharmacological Actions : Apoptotic, Enzyme Inhibitors
Additional Keywords : Plant Extracts
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Genistein and a fermented wheat germ extract (Avemar) may inhibit pancreatic cancer cell growth. Jan 01, 2002

Pubmed Data : Pancreas. 2002 Jan;24(1):26-33. PMID: 11741179
Article Published Date : Jan 01, 2002
Study Type : Commentary
Additional Links
Substances : Wheat Germ
Diseases : Pancreatic Cancer
Additional Keywords : Cancer as a Glucose-Based Disease
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This research demonstrated efficacy and safety of Iranian herbal medicines in alleviating PMS.Feb 28, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Avicenna J Phytomed. 2018 Mar-Apr;8(2):96-113. PMID: 29632841
Article Published Date : Feb 28, 2018
Study Type : Review
Additional Links
Substances : Chamomile, Chaste Tree (Chasteberry), Curcumin, Fennel, Flaxseed, Ginger, Lemon Balm, Orange, Saffron, St. Johns Wort, Valerian, Wheat Germ, Zataria multiflora
Diseases : Premenstrual syndrome
Additional Keywords : Traditional Iranian Medicine
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Wheat germ agglutinin-induced paraptosis-like cell death and protective autophagy is mediated by autophagy-linked FYVE inhibition.Oct 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2017 Oct 31 ;8(53):91209-91222. Epub 2017 Aug 24. PMID: 29207637
Article Published Date : Oct 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Wheat Germ
Diseases : Cervical Cancer
Pharmacological Actions : Apoptotic, Paraptosis
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Wheat germ extract decreases glucose uptake and RNA ribose formation but increases fatty acid synthesis in MIA pancreatic adenocarcinoma cells.Jul 31, 2001

Pubmed Data : Pancreas. 2001 Aug ;23(2):141-7. PMID: 11484916
Article Published Date : Jul 31, 2001
Study Type : In Vitro Study
Additional Links
Substances : Wheat Germ
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative
Additional Keywords : Plant Extracts
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Wheat germ protein could exert an effective antioxidant action by across the intestinal epithelium.Jul 31, 2019

Pubmed Data : J Food Sci. 2019 Aug ;84(8):2139-2146. Epub 2019 Jul 17. PMID: 31313302
Article Published Date : Jul 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Wheat Germ
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants
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Wheatgerm agglutinin (WGA) is cytotoxic to pancreatic cancer cells.Aug 01, 1999

Pubmed Data : Br J Cancer. 1999 Aug;80(11):1754-62. PMID: 10468292
Article Published Date : Aug 01, 1999
Study Type : In Vitro Study
Additional Links
Substances : Wheat Germ
Diseases : Pancreatic Cancer
Pharmacological Actions : Antineoplastic Agents, Antiproliferative

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