antioxidant https://greenmedinfo.com/category/therapeutic-actions/antioxidant en C. sempervirens and J. phoenicea leaf extracts show a remarkable effect in enhancing liver and kidney functions and may thus be of therapeutic potential in treatment hepatotoxicity and nephrotoxicity. https://greenmedinfo.com/article/c-sempervirens-and-j-phoenicea-leaf-extracts-show-remarkable-effect-enhancing- PMID:  World J Gastrointest Pharmacol Ther. 2010 Dec 6 ;1(6):123-31. PMID: 21577307 Abstract Title:  Protective role of Juniperus phoenicea and Cupressus sempervirens against CCl(4). Abstract:  AIM: To investigate the role of Cupressus sempervirens (C. sempervirens) and Juniperus phoenicea (J. phoenicea) extracts as therapeutic effect against CCl(4) with biochemical, histopathological evaluations. METHODS: A single intraperitoneal dose of 10% CCl(4) in olive oil (1 mL/kg body weight) was administered to a group of female Wister rats, sacrificed after 24 h (as the injury group). The other groups were given CCl(4) as described above and divided as follows: two groups of ten rats each were orally administered either J. phoenicea extract or C. sempervirens extract three times per week for six weeks and a further group administered CCl(4) was left for six weeks to allow self-recovery. At the end of experiment, the rats from all groups were sacrificed for sampling and for biochemical and histological analysis. RESULTS: Remarkable disturbances were observed in the levels of all tested parameters. On the other hand, rats injected with the toxic agent and left for one and a half month to self recover showed moderate improvements in the studied parameters while, treatment with both medicinal herbal extracts ameliorated the levels of the disturbed biochemical parameters. The group treated with J. phoenicea extract showed a remarkable improvement in comparison to the CCl(4) treated group. The C. sempervirens group revealing an even more remarkable effect showing histopathological liver&amp;kidney profiles close to those of the control group. CONCLUSION: C. sempervirens and J. phoenicea leaf extracts show a remarkable effect in enhancing liver and kidney functions and may thus be of therapeutic potential in treatment hepatotoxicity and nephrotoxicity. https://greenmedinfo.com/article/c-sempervirens-and-j-phoenicea-leaf-extracts-show-remarkable-effect-enhancing-#comments Flavonoids Liver Disease antioxidant Hepatoprotective C. Sempervirens Extract J. Phoenicea Extract Liver Enzymes Plant Extracts Animal Study Fri, 06 Apr 2012 07:14:38 +0000 greenmedinfo 73972 at https://greenmedinfo.com Pistachios contain a heart-healthy fatty acid profile and several phytochemicals that help maintain healthy antioxidant and anti-inflammatory activity. https://greenmedinfo.com/article/pistachios-contain-heart-healthy-fatty-acid-profile-and-several-phytochemicals PMID:  Nutr Rev. 2012 Apr ;70(4):234-40. PMID: 22458696 Abstract Title:  Pistachio nuts: composition and potential health benefits. Abstract:  The pistachio is a nutrient-dense nut with a heart-healthy fatty-acid profile as well as protein, dietary fiber, potassium, magnesium, vitamin K,γ-tocopherol, and a number of phytochemicals. The pistachio&#039;s unique green and purple kernel color is a result of its lutein and anthocyanin content. Among nuts, pistachios contain the highest levels of potassium, γ-tocopherol, vitamin K, phytosterols, and xanthophyll carotenoids. Five published randomized cardiovascular trials have shown that pistachios promote heart-healthy blood lipid profiles. Exploratory clinical studies suggest that pistachios help maintain healthy antioxidant and anti-inflammatory activity, glycemic control, and endothelial function. When consumed in moderation, pistachios may help control body weight because of their satiety and satiation effects and their reduced net metabolizable energy content. One study with subjects in a weight-loss program demonstrated lower body mass index and triglyceride levels in individuals who consumed pistachios compared with thosewho consumed an isocaloric pretzel snack. Emerging research suggests that the addition of pistachios to high-glycemic meals may lower the overall postprandial glycemic response. This review examines the nutrients and phytochemicals in pistachios as well as the potential health effects of these nuts. https://greenmedinfo.com/article/pistachios-contain-heart-healthy-fatty-acid-profile-and-several-phytochemicals#comments Cardiovascular Diseases Pistachio nut anti-inflammatory antioxidant Anti Inflammatory Antioxidants CARDIOVASCULAR Glycemic Load Healthy Fats Meta Analysis Nuts: All Sun, 01 Apr 2012 20:09:44 +0000 greenmedinfo 73821 at https://greenmedinfo.com Sulforaphane's anti-inflammatory, antioxidant, and neuroprotective benefits attentuate autoimmune encephalomyelitis in an animal model of Multiple Sclerosis. https://greenmedinfo.com/article/sulforaphanes-anti-inflammatory-antioxidant-and-neuroprotective-benefits-atten PMID:  J Korean Med Sci. 2019 Jul 22 ;34(28):e197. Epub 2019 Jul 22. PMID: 31327180 Abstract Title:  The Anti-Inflammatory Effect of Sulforaphane in Mice with Experimental Autoimmune Encephalomyelitis. Abstract:  BACKGROUND: Multiple sclerosis (MS) is an immune-associated inflammatory disorder of the central nervous system and results in serious disability. Although many disease-modifying therapy drugs have been developed, these drugs have shown limited clinical efficacy and some adverse effects in previous studies, therefore, there has been reasonable need for less harmful and cost-effective therapeutics. Herein, we tested the anti-inflammatory effect of sulforaphane (SFN) in a mouse model of experimental autoimmune encephalomyelitis (EAE).METHODS: The EAE mice were randomly assigned into two experimental groups: the phosphate-buffered saline (PBS)-treated EAE group and SFN-treated EAE group. After EAE mice induction by auto-immunization against the myelin oligodendrocyte glycoprotein peptide, we evaluated EAE symptom scores and biochemical analyses such as infiltration of inflammatory cells and demyelination of the spinal cord. Furthermore, western blotting was performed using the spinal cords of EAE mice.RESULTS: In the behavioral study, the SFN-treated EAE mice showed favorable clinical scores compared with PBS-treated EAE mice at the 13th day (1.30± 0.15 vs. 1.90 ± 0.18;= 0.043) and 14th day (1.80± 0.13 vs. 2.75 ± 0.17;= 0.003). Additionally, the biochemical studies revealed that SFN treatment inhibited the inflammatory infiltration, demyelinating injury of the spinal cords, and the up-regulation of inducible nitric oxide synthase in the EAE mice.CONCLUSION: The SFN treatment showed anti-inflammatory and anti-oxidative effects in the EAE mice. Conclusively, this study suggests that SFN has neuroprotective effects via anti-inflammatory processing, so it could be a new therapeutic or nutritional supplement for MS. <p><a href="https://greenmedinfo.com/article/sulforaphanes-anti-inflammatory-antioxidant-and-neuroprotective-benefits-atten" target="_blank">read more</a></p> https://greenmedinfo.com/article/sulforaphanes-anti-inflammatory-antioxidant-and-neuroprotective-benefits-atten#comments Autoimmune Diseases Multiple Sclerosis Sulforaphane anti-inflammatory Anti-Inflammatory Agents antioxidant Antioxidant Effects neuro-protective Neuroprotective Agents Nitric Oxide Inhibitor Antioxidant Autoimmune Diseases Cruciferous Vegetables Multiple Sclerosis Phytotherapy Sulforaphane Animal Study Wed, 24 Jul 2019 18:15:46 +0000 greenmedinfo 191796 at https://greenmedinfo.com Sulforphane's antioxidant properties make it an effective neuroprotective agent. More studies are needed to determine the exact implications in neurological disease. https://greenmedinfo.com/article/sulforphanes-antioxidant-properties-make-it-effective-neuroprotective-agent-mo PMID:  Brain Circ. 2019 Apr-Jun;5(2):74-83. Epub 2019 Jun 27. PMID: 31334360 Abstract Title:  The neuroprotective mechanisms and effects of sulforaphane. Abstract:  Sulforaphane (SFN) is a phytochemical found in cruciferous vegetables. It has been shown to have many protective effects against many diseases, including multiple types of cancer. SFN is a potent activator of the nuclear factor erythroid 2-related factor 2 (Nrf2) antioxidant response element (ARE) genetic pathway. Upregulation of Nrf2-ARE increases the availability of multiple antioxidants. A substantial amount of preclinical research regarding the ability of SFN to protect the nervous system from many diseases and toxins has been done, but only a few small human trials have been completed. Preclinical data suggest that SFN protects the nervous system through multiple mechanisms and may help reduce the risk of many diseases and reduce the burden of symptoms in existing conditions. This review focuses on the literature regarding the protective effects of SFN on the nervous system. A discussion of neuroprotective mechanisms is followed by a discussion of the protective effects elicited by SFN administration in a multitude of neurological diseases and toxin exposures. SFN is a promising neuroprotective phytochemical which needs further human trials to evaluate its efficacy in preventing and decreasing the burden of many neurological diseases. <p><a href="https://greenmedinfo.com/article/sulforphanes-antioxidant-properties-make-it-effective-neuroprotective-agent-mo" target="_blank">read more</a></p> https://greenmedinfo.com/article/sulforphanes-antioxidant-properties-make-it-effective-neuroprotective-agent-mo#comments Sulforaphane Antioxidant antioxidant Antioxidant Effects Antioxidants antioxidants neuro-protective Neuroprotective Agents NF-E2-Related Factor-2 (Nrf2) Modulator Nrf2 activation Antioxidant effects Antioxidant Systems Cruciferous Vegetables Neurodegenerative diseases Neuroprotective Agents Nrf2 activation Phytotherapy Sulforaphane Review Wed, 24 Jul 2019 18:33:49 +0000 greenmedinfo 191800 at https://greenmedinfo.com Top 10 Reasons to Eat Your Cruciferous Veggies https://greenmedinfo.com/blog/top-10-reasons-eat-your-cruciferous-veggies <div class="copyright">This article is copyrighted by GreenMedInfo LLC, 2019<br/><strong><a href="/greenmedinfocom-re-post-guidelines">Visit our Re-post guidelines</a></strong></div><p class="rtecenter"><img alt="10 Reasons to Eat Your Cruciferous Vegetables" src="//cdn.greenmedinfo.com/sites/default/files/ckeditor/lrossi/images/cruciferous_vegetables_greenmedinfo.jpg" style="width: 650px; height: 433px;" title="Top 10 Reasons to Eat Your Cruciferous Veggies" /></p> <p><span style="font-size:18px;"><em><strong>Everyone knows that eating vegetables has profound health benefits. But, like all foods, not all vegetables are created the same. A few vegetables appear to be downright "miracle" foods!</strong></em></span></p> <p>One such group of veggies are those of the <em>Brassica</em> family; commonly known as cruciferous. These include broccoli, Brussels sprouts, cabbage, cauliflower, kale, radish, rutabaga, turnip and even arugula.&nbsp;</p> <p><em>What makes this group of veggies so special?</em> <strong><a href="/substance/sulforaphane" rel="dofollow" target="_blank" title="Top 10 Reasons to Eat Your Cruciferous Veggies">Sulforaphane</a></strong>.&nbsp;</p><p><a href="https://greenmedinfo.com/blog/top-10-reasons-eat-your-cruciferous-veggies" target="_blank">read more</a></p> https://greenmedinfo.com/blog/top-10-reasons-eat-your-cruciferous-veggies#comments Alzheimer's Disease Broccoli Broccoli Sprouts Brussels Sprouts Cancers: All Cruciferous Vegetables Depression Diabetes Mellitus: Type 2 Heart Disease Sulforaphane anti-cancer antioxidant Health Guides: Healing Foods Alzheimer's disease Broccoli Broccoli Sprouts Brussels sprouts Cancers: All Cruciferous Vegetables Depression Diabetes mellitus: Type 2 Heart Disease Sulforaphane Tue, 04 Jun 2019 11:00:41 +0000 GMI Research Group 142718 at https://greenmedinfo.com