Sucralose https://greenmedinfo.com/category/keywords/Sucralose en Sucralose induces biochemical responses, including neurotoxicity, in Daphnia magna. https://greenmedinfo.com/article/sucralose-induces-biochemical-responses-including-neurotoxicity-daphnia-magna n/a PMID:  PLoS One. 2014 ;9(4):e92771. Epub 2014 Apr 3. PMID: 24699280 Abstract Title:  Sucralose induces biochemical responses in Daphnia magna. Abstract:  The intense artificial sweetener sucralose has no bioconcentration properties, and no adverse acute toxic effects have been observed in standard ecotoxicity tests, suggesting negligible environmental risk. However, significant feeding and behavioural alterations have been reported in non-standard tests using aquatic crustaceans, indicating possible sublethal effects. We hypothesized that these effects are related to alterations in acetylcholinesterase (AChE) and oxidative status in the exposed animals and investigated changes in AChE and oxidative biomarkers (oxygen radical absorbing capacity, ORAC, and lipid peroxidation, TBARS) in the crustacean Daphnia magna exposed to sucralose (0.0001-5 mg L(-1)). The sucralose concentration was a significant positive predictor for ORAC, TBARS and AChE in the daphnids. Moreover, the AChE response was linked to both oxidative biomarkers, with positive and negative relationships for TBARS and ORAC, respectively. These joint responses support our hypothesis and suggest that exposure to sucralose may induce neurological and oxidative mechanisms with potentially important consequences for animal behaviour and physiology. https://greenmedinfo.com/article/sucralose-induces-biochemical-responses-including-neurotoxicity-daphnia-magna#comments Lipid Peroxidation Neurotoxic Sucralose (aka Splenda) Lipid Peroxidation Splenda Sucralose Insect Study Sat, 07 Jan 2017 03:15:49 +0000 greenmedinfo 141618 at https://greenmedinfo.com Sucralose inhibits thyroid function and metabolism in doses within the range of the human acceptable daily intake. https://greenmedinfo.com/article/sucralose-inhibits-thyroid-function-and-metabolism-doses-within-range-human-ac n/a PMID:  Eur J Nutr. 2016 Dec 31. Epub 2016 Dec 31. PMID: 28040879 Abstract Title:  Type of sweet flavour carrier affects thyroid axis activity in male rats. Abstract:  PURPOSE: Non-nutritive sweeteners are the most widely used food additives worldwide. However, their metabolic outcomes are still a matter of controversy and their effect on the thyroid activity, a key regulator of metabolism, has not been previously studied. Therefore, we aim to determine the influence of the sweet type flavour carrier on selected parameters of thyroid axis activity. METHODS: Male Sprague-Dawley rats (n = 105) were divided into 3 groups fed ad libitum for three weeks isocaloric diets (3.76 ± 0.5 kcal/g): two with the same sweet flavour intensity responded to 10% of sucrose (with sucrose-SC-and sucralose-SU) and one non-sweet diet (NS). To evaluate the post-ingested effects, animals were euthanised at fast and 30, 60, 120, 180 min after meal. RESULTS: The results obtained indicate that both the presence and the type of sweet taste flavour carrier affect thyroid axis activity both at fasting and postprandial state. Compared to diet with sucrose which stimulates thyroid axis activity, sucralose addition diminishes thyroid hormone synthesis as thyroid peroxidase (TPO) activity, plasma thyroxine (T4), and triiodothyronine (T3) concentration was lower than in SC and NS while in non-sweet diet the lowest level of hepatic deiodinase type 1 (DIO1) and the highest reverse T3 (rT3) level indicate on altered thyroid hormone peripheral metabolism. CONCLUSION: Both the presence and the type of sweet flavour carrier have a significant impact on thyroid axis activity. Our findings suggest that this organochlorine sweetener is metabolically active and might exacerbate metabolic disorders via an adverse effect on thyroid hormone metabolism. https://greenmedinfo.com/article/sucralose-inhibits-thyroid-function-and-metabolism-doses-within-range-human-ac#comments HPA Axis Dysregulation Hypothyroidism Overweight Endocrine Disruptor: Thyroid Neurotoxic Sucralose (aka Splenda) HPA Axis Dysregulation hypothyroidism overweight Splenda Sucralose Animal Study Sat, 07 Jan 2017 16:59:00 +0000 greenmedinfo 141628 at https://greenmedinfo.com Top 5 Reasons Never to Use Splenda https://greenmedinfo.com/blog/top-5-reasons-never-use-splenda <div class="copyright">This article is copyrighted by GreenMedInfo LLC, 2023<br/><strong><a href="/greenmedinfocom-re-post-guidelines">Visit our Re-post guidelines</a></strong></div><p class="rtecenter" dir="ltr"><img alt="Top 5 Reasons Never To Use Splenda" src="//cdn.greenmedinfo.com/sites/default/files/ckeditor/lrossi/images/splenda_dangers_greenmedinfo(1).jpg" style="width: 600px; height: 375px;" title="Top 5 Reasons Never To Use Splenda" /></p> <p dir="ltr"><em style="font-size: 18px; letter-spacing: 0px;"><strong><span id="docs-internal-guid-91423fbc-e17d-84e8-1329-8d99076ba241">Splenda is marketed as a no-calorie, no-guilt sugar substitute. Blood sugar stable, it "passes right through" the body, so it's safe for diabetics AND you won't gain weight! Are these claims masking the ugly truth about this chemical imposter?&nbsp;As&nbsp;mounting research shows, when it comes to our diet, there is no free lunch</span></strong></em></p> <p dir="ltr"><strong style="letter-spacing: 0px;"><span style="font-size:18px;"><span id="docs-internal-guid-91423fbc-e17d-84e8-1329-8d99076ba241">Splenda's Spurious Claims</span></span></strong></p><p><a href="https://greenmedinfo.com/blog/top-5-reasons-never-use-splenda" target="_blank">read more</a></p> https://greenmedinfo.com/blog/top-5-reasons-never-use-splenda#comments Diabetes Nonalcoholic fatty liver disease (NAFLD) Obesity Thyroid Cancer Artificial Sweeteners Blood Sugar Problems Endocrine Disruptor Sucralose (aka Splenda) artificial sweetener Diabetes Nonalcoholic fatty liver disease (NAFLD) obesity Splenda Sucralose Thyroid Cancer Top 5 Reasons Never To Use Splenda Tue, 15 Aug 2017 22:11:08 +0000 Sayer Ji 151617 at https://greenmedinfo.com Yogurt's Health Damaging Ingredients https://greenmedinfo.com/blog/yogurts-health-damaging-ingredients <div class="copyright">This article is copyrighted by GreenMedInfo LLC, 2015<br/><strong><a href="/greenmedinfocom-re-post-guidelines">Visit our Re-post guidelines</a></strong></div><p class="rtecenter"><br /> <img alt="Yogurt's Health Damaging Ingredients" src="//cdn.greenmedinfo.com/sites/default/files/ckeditor/stebu/images/yogurt_problems2.jpg" style="width: 600px; height: 401px;" /></p> <p><em>Yoplait Cherry Cheesecake Mousse Yogurt</em></p> <p><em>Yoplait Thick &amp; Creamy Cinnamon Roll Yogurt&nbsp;</em></p> <p><em>Yoplait Red Velvet Cupcake Yogurt</em></p> <p><em>Great Value Low Fat Vanilla Yogurt</em></p> <p><em>Dannon Toasted Coconut Vanilla Yogurt&nbsp;</em></p> <p><strong>Don't kid yourself.</strong></p> <p>This is <strong>NOT</strong> healthy <strong><a href="/substance/yoghurt" target="_blank">yogurt</a></strong>. This is artificially flavored dessert.</p> <p>Many brands of yogurt in the grocery store are using&nbsp;highly processed ingredients:</p><p><a href="https://greenmedinfo.com/blog/yogurts-health-damaging-ingredients" target="_blank">read more</a></p> https://greenmedinfo.com/blog/yogurts-health-damaging-ingredients#comments Carrageenan Leukemia Obesity yogurt Aspartame Fructose High Fructose Corn Syrup Sucralose (aka Splenda) aspartame Carrageenan Fructose High Fructose Corn Syrup leukemia obesity Sucralose yogurt Thu, 15 Jan 2015 20:14:10 +0000 ErinChamerlik 116002 at https://greenmedinfo.com