Pseudomonas aeruginosa https://greenmedinfo.com/category/keywords/Pseudomonas%20aeruginosa en Lavendula angustifolia essential oil was shown in most cases to interact synergistically with conventional antimicrobials. https://greenmedinfo.com/article/lavendula-angustifolia-essential-oil-was-shown-most-cases-interact-synergistic n/a PMID:  Evid Based Complement Alternat Med. 2016 ;2016:2752739. Epub 2016 Nov 6. PMID: 27891157 Abstract Title:  The In Vitro Antimicrobial Effects of Lavandula angustifolia Essential Oil in Combination with Conventional Antimicrobial Agents. Abstract:  The paper focuses on the in vitro antimicrobial activity of Lavandula angustifolia Mill. (lavender) essential oil in combination with four commercial antimicrobial agents. Stock solutions of chloramphenicol, ciprofloxacin, nystatin, and fusidic acid were tested in combination with L. angustifolia essential oil. The antimicrobial activities of the combinations were investigated against the Gram-positive bacterial strain Staphylococcus aureus (ATCC 6538) and Gram-negative Pseudomonas aeruginosa (ATCC 27858) and Candida albicans (ATCC 10231) was selected to represent the yeasts. The antimicrobial effect was performed using the minimum inhibitory concentration (MIC) microdilution assay. Isobolograms were constructed for varying ratios. The most prominent interaction was noted when L. angustifolia essential oil was combined with chloramphenicol and tested against the pathogen P. aeruginosa (ΣFIC of 0.29). Lavendula angustifolia essential oil was shown in most cases to interact synergistically with conventional antimicrobials when combined in ratios where higher volumes of L. angustifolia essential oil were incorporated into the combination. https://greenmedinfo.com/article/lavendula-angustifolia-essential-oil-was-shown-most-cases-interact-synergistic#comments Candida Albicans Lavender: Essential Oil Pseudomonas aeruginosa Staphylococcus aureus infection Antimicrobial Candida Albicans Essential Oils lavender oil lavendula Natural Substance Synergy Pseudomonas aeruginosa Staphylococcus aureus infection In Vitro Study Fri, 02 Dec 2016 01:36:35 +0000 greenmedinfo 139769 at https://greenmedinfo.com Natural isothiocyanates represent a promising group of natural anti-infective compounds with activity against Pseudomonas aeruginosa biofilms. https://greenmedinfo.com/article/natural-isothiocyanates-represent-promising-group-natural-anti-infective-compo n/a PMID:  Fitoterapia. 2017 Jun ;119:57-63. Epub 2017 Apr 5. PMID: 28390975 Abstract Title:  Natural isothiocyanates express antimicrobial activity against developing and mature biofilms of Pseudomonas aeruginosa. Abstract:  BACKGROUND: The antimicrobial properties of natural isothiocyanates (ITCs) found in plants such as nasturtium (Tropaeolum majus) and horseradish (Armoracia rusticana), and the need of new chemotherapeutic options for treatment of infections caused by multidrug-resistant and biofilm-forming Gram-negative bacteria such as Pseudomonas aeruginosa (Pa), led us to evaluate the effects of three major ITCs, allylisothiocyanate (AITC), benzylisothiocyanate (BITC), and phenylethyl-isothiocyanate (PEITC), and a mixture (ITCM) adapted to the ITC composition after release of active components out of natural sources. MATERIAL/METHODS: Out of 105Pa isolates 27 isolates with increased biofilm formation were selected for testing. The effects of ITCs on Pa were evaluated regarding (1) planktonic bacterial proliferation, (2) biofilm formation, (3) metabolic activity in mature biofilms, and (4) synergism of ITCs and antibiotics. RESULTS: (1) Each ITC had anti-Pa activity. Mean minimum inhibitory concentrations (MICs) were (μg/ml, mean±standard deviation): AITC 103±6.9; BITC, 2145±249; PEITC 29,423±1652; and ITCM, 140±5. (2) Treating bacteria with PEITC and ITCM in concentrations below the MIC significantly inhibited biofilm formation. Particularly, ITCM reduced biofilm mass and bacterial proliferation. (3) ITCssignificantly inhibited metabolic activity in mature biofilms. (4) Combining ITCs with meropenem synergistically increased antimicrobial efficacy on Pa biofilms. CONCLUSIONS: ITCs represent a promising group of natural anti-infective compounds with activity against Pa biofilms. https://greenmedinfo.com/article/natural-isothiocyanates-represent-promising-group-natural-anti-infective-compo#comments Horseradish Isothiocyanates Pseudomonas aeruginosa Anti-Bacterial Agents Anti-Bacterial Agents Biofilm Horseradish Isothiocyanates Pseudomonas aeruginosa In Vitro Study Tue, 02 Jan 2018 19:41:26 +0000 greenmedinfo 157921 at https://greenmedinfo.com Royal jelly may be a useful supplement as complementary and alternative medicine for preventing respiratory infection caused by P. aeruginosa. https://greenmedinfo.com/article/royal-jelly-may-be-useful-supplement-complementary-and-alternative-medicine-pr n/a PMID:  Biomed Res Int. 2017 ;2017:3191752. Epub 2017 Sep 17. PMID: 29075644 Abstract Title:  Royal Jelly Inhibits Pseudomonas aeruginosa Adherence and Reduces Excessive Inflammatory Responses in Human Epithelial Cells. Abstract:  Pseudomonas aeruginosa is a Gram-negative bacterium and causes respiratory infection especially in elderly patients. Royal jelly has been used worldwide as a traditional remedy and as a nutrient; however, the effect against P. aeruginosa is unclear. The aim of this study was to analyze antibacterial, antiadherent, and anti-inflammatory effects of royal jelly against P. aeruginosa. Wild-type strain PAO1 and clinical isolates of P. aeruginosa were used for antibacterial assay and antiadherent assay to abiotic surface and epithelial cells, which are pharynx (Detroit 562) and lung (NCI-H292) epithelial cells. In anti-inflammatory assay, epithelial cells were pretreated with royal jelly before bacterial exposure to investigate its inhibitory effect on interleukin (IL-8) and macrophage inflammatory protein-3α/CCL20 overproduction. Although royal jelly did not have antibacterial activity at concentration of 50% w/v, antiadherent activity was confirmed on the abiotic surface and epithelial cells under concentration of 25%. Pretreatment with royal jelly significantly inhibited overproduction of IL-8 and CCL20 from both cells. These results demonstrated that royal jelly inhibits P. aeruginosa adherence and protects epithelial cells from excessive inflammatory responses against P. aeruginosa infection. Our findings suggested that royal jelly may be a useful supplement as complementary and alternative medicine for preventing respiratory infection caused by P. aeruginosa. https://greenmedinfo.com/article/royal-jelly-may-be-useful-supplement-complementary-and-alternative-medicine-pr#comments Pseudomonas aeruginosa Royal Jelly Anti-Inflammatory Agents Anti-Inflammatory Agents Pseudomonas aeruginosa Royal Jelly In Vitro Study Thu, 08 Feb 2018 03:14:11 +0000 greenmedinfo 159482 at https://greenmedinfo.com Saudi honey inhibit the growth of bacterial strains and that honey can be used as complementary antimicrobial agent. https://greenmedinfo.com/article/saudi-honey-inhibit-growth-bacterial-strains-and-honey-can-be-used-complementa n/a PMID:  Vet World. 2017 Feb ;10(2):233-237. Epub 2017 Feb 21. PMID: 28344408 Abstract Title:  Potential antibacterial activity of some Saudi Arabia honey. Abstract:  AIM: The aim of this study was to investigate the potential antibacterial activity of some Saudi Arabia honey against selected bacterial strains of medical importance. MATERIALS AND METHODS: A total of 10 Saudi Arabia honey used to evaluate their antimicrobial activity against some antibiotic-resistant pathogenic bacterial strains. The bacterial strains were Staphylococcus aureus, Streptococcus pyogenes, Klebsiella pneumoniae, Escherichia coli, and Pseudomonas aeruginosa. RESULTS: The antibacterial activity of Saudi honey against five bacterial strains showed different levels of inhibition according to the type of honey. The overall results showed that the potential activity was differing according to the pathogen and honey type. CONCLUSION: It could be concluded that the Saudi honey inhibit the growth of bacterial strains and that honey can be used as complementary antimicrobial agent against selected pathogenic bacteria. https://greenmedinfo.com/article/saudi-honey-inhibit-growth-bacterial-strains-and-honey-can-be-used-complementa#comments Escherichia coli Infections Honey Klebsiella Infections Pseudomonas aeruginosa Staphylococcus aureus infection Streptococcus pyogenes Anti-Bacterial Agents Anti-Bacterial Agents Escherichia coli Infections Honey Klebsiella Infections Pseudomonas aeruginosa Staphylococcus aureus infection Streptococcus pyogenes In Vitro Study Thu, 28 Sep 2017 00:03:09 +0000 greenmedinfo 153491 at https://greenmedinfo.com