Artificial Sweeteners https://greenmedinfo.com/category/keywords/Artificial%20Sweeteners en 4 Sugar Alternatives That Won't Poison You https://greenmedinfo.com/blog/4-sugar-alternatives-wont-poison-you <div class="copyright">This article is copyrighted by GreenMedInfo LLC, 2022<br/><strong><a href="/greenmedinfocom-re-post-guidelines">Visit our Re-post guidelines</a></strong></div><p class="rtecenter"><img alt="" src="//cdn.greenmedinfo.com/sites/default/files/ckeditor/blank.justin/images/DietWithoutDeprivation.jpg" style="width: 600px; height: 315px;" title="4&nbsp;Sugar Alternatives That Won't Poison You" /></p> <p><span style="font-size:18px;"><em><strong>You may think that staying slim and eating healthfully means NO sweets, but guess what? There are natural and delicious sweeteners that won't wreck your diet, and even have therapeutic 'side benefits'</strong></em></span></p> <p><span style="letter-spacing: 0px;">No arena of health and wellness is more debatable than what we </span><strong style="letter-spacing: 0px;"><em>should </em></strong><span style="letter-spacing: 0px;">be eating. Looking back through time, the foods that constitute a healthy diet have changed so dramatically, you can literally mark the passage of time by the coming and going of dietary fads.</span></p><p><a href="https://greenmedinfo.com/blog/4-sugar-alternatives-wont-poison-you" target="_blank">read more</a></p> https://greenmedinfo.com/blog/4-sugar-alternatives-wont-poison-you#comments Cardiovascular Disease Dental Caries Diabetes Honey Hypertension Molasses Nonalcoholic fatty liver disease (NAFLD) Obesity Overweight Stevia Xylitol GMOs High Fructose Corn Syrup Sugar Sugary soda Artificial Sweeteners GMO High Fructose Corn Syrup High Sugar Diet toxicity from artificial sweeteners Thu, 03 Nov 2022 13:01:16 +0000 Sayer Ji 152956 at https://greenmedinfo.com Aspartames break down product phenylalanine, can inhibit the protective effects of intestinal alkaline phosphatase. https://greenmedinfo.com/article/aspartames-break-down-product-phenylalanine-can-inhibit-protective-effects-int n/a PMID:  Appl Physiol Nutr Metab. 2016 Nov 18:1-7. Epub 2016 Nov 18. PMID: 27997218 Abstract Title:  Inhibition of the gut enzyme intestinal alkaline phosphatase may explain how aspartame promotes glucose intolerance and obesity in mice. Abstract:  Diet soda consumption has not been associated with tangible weight loss. Aspartame (ASP) commonly substitutes sugar and one of its breakdown products is phenylalanine (PHE), a known inhibitor of intestinal alkaline phosphatase (IAP), a gut enzyme shown to prevent metabolic syndrome in mice. We hypothesized that ASP consumption might contribute to the development of metabolic syndrome based on PHE&#039;s inhibition of endogenous IAP. The design of the study was such that for the in vitro model, IAP was added to diet and regular soda, and IAP activity was measured. For the acute model, a closed bowel loop was created in mice. ASP or water was instilled into it and IAP activity was measured. For the chronic model, mice were fed chow or high-fat diet (HFD) with/without ASP in the drinking water for 18 weeks. The results were that for the in vitro study, IAP activity was lower (p&lt;0.05) in solutions containing ASP compared with controls. For the acute model, endogenous IAP activity was reduced by 50% in the ASP group compared with controls (0.2± 0.03 vs 0.4 ± 0.24) (p = 0.02). For the chronic model, mice in the HFD + ASP group gained more weight compared with the HFD + water group (48.1 ± 1.6 vs 42.4 ± 3.1, p = 0.0001). Significant difference in glucose intolerance between the HFD ± ASP groups (53 913 ± 4000.58 (mg·min)/dL vs 42 003.75 ± 5331.61 (mg·min)/dL, respectively, p = 0.02). Fasting glucose and serum tumor necrosis factor-alpha levels were significantly higher in the HFD + ASP group (1.23- and 0.87-fold increases, respectively, p = 0.006 and p = 0.01). In conclusion, endogenous IAP&#039;s protective effects in regard to the metabolic syndrome may be inhibited by PHE, a metabolite of ASP, perhaps explaining the lack of expected weight loss and metabolic improvements associated with diet drinks. https://greenmedinfo.com/article/aspartames-break-down-product-phenylalanine-can-inhibit-protective-effects-int#comments Insulin Resistance Obesity Artificial Sweeteners Aspartame Obesogenic Artificial Sweeteners aspartame Insulin Resistance obesity Risk Factors Animal Study Tue, 27 Dec 2016 17:15:19 +0000 greenmedinfo 141025 at https://greenmedinfo.com