Otitis https://greenmedinfo.com/category/keywords/Otitis en The results of this preliminary study indicate a possible role of honey eardrops in eczematous ear disease. https://greenmedinfo.com/article/results-preliminary-study-indicate-possible-role-honey-eardrops-eczematous-ear n/a PMID:  Otolaryngol Head Neck Surg. 2017 Jul 1:194599817718782. Epub 2017 Jul 1. PMID: 28695767 Abstract Title:  Treatment of Recurrent Eczematous External Otitis with Honey Eardrops: A Proof-of-Concept Study. Abstract:  Eczematous external otitis is a chronic inflammatory disease and often difficult to treat. Our objective was to investigate the clinical effect and in vitro antibacterial potential of medical honey eardrops as treatment of eczematous external otitis. In a prospective study, 15 patients diagnosed with recurrent eczematous external otitis were treated with medical honey eardrops for 2 weeks. The following clinical outcomes were evaluated: visual analog scale of ear complaints, score of eczema, and eradication of bacterial infection. Furthermore, the antibacterial effect of honey eardrops against different bacterial strains was tested in vitro. Treatment resulted in less discomfort and itching and decreased signs of eczema, with high patient satisfaction and without adverse reactions. Honey eardrops showed a strong in vitro inhibitory activity against all tested strains but did not eradicate Staphylococcus aureus infection in vivo. The results of this preliminary study indicate a possible role of honey eardrops in eczematous ear disease. https://greenmedinfo.com/article/results-preliminary-study-indicate-possible-role-honey-eardrops-eczematous-ear#comments Eczema Honey Otitis Anti-Bacterial Agents Anti-Bacterial Agents eczema Honey Otitis Human Study Human In Vitro Wed, 27 Sep 2017 23:17:42 +0000 greenmedinfo 153489 at https://greenmedinfo.com Thymoquinone may be considered for topical application alone in the treatment of acute otitis externa. https://greenmedinfo.com/article/thymoquinone-may-be-considered-topical-application-alone-treatment-acute-otiti n/a PMID:  J Int Adv Otol. 2017 Dec 14. Epub 2017 Dec 14. PMID: 29283096 Abstract Title:  The Role of Topical Thymoquinone in the Treatment of Acute Otitis Externa; an Experimental Study in Rats. Abstract:  OBJECTIVE: The aim of this experimental study was to compare the dose-related effect of topical thymoquinone (TQ) with other topical agents used in the management of acute otitis externa (AOE) in a rat model. MATERIALS AND METHODS: Forty-eight male Wistar albino rats were divided into six groups each with eight rats per group. Group I was the control group with no external otitis, whereas external otitis were created in the other five groups (study groups). Dexamethasone, 0.1% TQ, 0.4% TQ, ciprofloxacin, and 0.9% saline (NaCl) drops was applied once daily in Groups II-VI, respectively. The treatment was administered regularly for 10 days. Pathologic and microbiologic evaluation were performed. Pathologically, the thicknesses of the stroma and the epithelium in the external auditory canal (EAC) were measured using an occulometer. Edema in the stroma, density of inflammatory cells and blood vessels, presence of fibroblasts, and changes in collagen fibers in the EAC were evaluated in five different areas to obtain the area of highest concentration and classified into four grades (0=no change, 1=mild, 2=moderate, 3=severe). RESULTS: The higher concentration of TQ (0.4%) was more effective than dexamethasone and 0.1% TQ with respect to antibacterial and the anti-inflammatory properties. CONCLUSION: TQ, particularly at a concentration of 0.4%, may be considered for topical application alone in the treatment of AOE, without any requirement for a combined treatment. https://greenmedinfo.com/article/thymoquinone-may-be-considered-topical-application-alone-treatment-acute-otiti#comments Otitis Thymoquinone Anti-Bacterial Agents Anti-Inflammatory Agents Anti-Bacterial Agents Anti-Inflammatory Agents Otitis Superiority of Natural Substances versus Drugs thymoquinone Animal Study Tue, 09 Jan 2018 19:53:27 +0000 greenmedinfo 158254 at https://greenmedinfo.com