Electromagnetic Hypersensitivity https://greenmedinfo.com/category/keywords/Electromagnetic%20Hypersensitivity en This study indicates that tinnitus is associated with subjective electromagnetic hypersensitivity. https://greenmedinfo.com/article/study-indicates-tinnitus-associated-subjective-electromagnetic-hypersensitivit PMID:  PLoS One. 2009 ;4(3):e5026. Epub 2009 Mar 27. PMID: 19325894 Abstract Title:  Association of tinnitus and electromagnetic hypersensitivity: hints for a shared pathophysiology? Abstract:  BACKGROUND: Tinnitus is a frequent condition with high morbidity and impairment in quality of life. The pathophysiology is still incompletely understood. Electromagnetic fields are discussed to be involved in the multi-factorial pathogenesis of tinnitus, but data proofing this relationship are very limited. Potential health hazards of electromagnetic fields (EMF) have been under discussion for long. Especially, individuals claiming themselves to be electromagnetic hypersensitive suffer from a variety of unspecific symptoms, which they attribute to EMF-exposure. The aim of the study was to elucidate the relationship between EMF-exposure, electromagnetic hypersensitivity and tinnitus using a case-control design.METHODOLOGY: Tinnitus occurrence and tinnitus severity were assessed by questionnaires in 89 electromagnetic hypersensitive patients and 107 controls matched for age-, gender, living surroundings and workplace. Using a logistic regression approach, potential risk factors for the development of tinnitus were evaluated.FINDINGS: Tinnitus was significantly more frequent in the electromagnetic hypersensitive group (50.72% vs. 17.5%) whereas tinnitus duration and severity did not differ between groups. Electromagnetic hypersensitivity and tinnitus were independent risk factors for sleep disturbances. However, measures of individual EMF-exposure like e.g. cell phone use did not show any association with tinnitus.CONCLUSIONS: Our data indicate that tinnitus is associated with subjective electromagnetic hypersensitivity. An individual vulnerability probably due to an over activated cortical distress network seems to be responsible for, both, electromagnetic hypersensitivity and tinnitus. Hence, therapeutic efforts should focus on treatment strategies (e.g. cognitive behavioral therapy) aiming at normalizing this dysfunctional distress network. <p><a href="https://greenmedinfo.com/article/study-indicates-tinnitus-associated-subjective-electromagnetic-hypersensitivit" target="_blank">read more</a></p> https://greenmedinfo.com/article/study-indicates-tinnitus-associated-subjective-electromagnetic-hypersensitivit#comments Tinnitus Electromagnetic Field Harms Electromagnetic Radiation Microwave Radiation Mobile Phone Radiation Electromagnetic Hypersensitivity EMF Human Study Fri, 16 Aug 2019 19:35:58 +0000 greenmedinfo 193965 at https://greenmedinfo.com 50 Hz magnetic fields and 915 MHz microwaves can induce genotoxic damage in both healthy and electromagnetic hypersensitive lymphocytes in vitro. https://greenmedinfo.com/article/50-hz-magnetic-fields-and-915-mhz-microwaves-can-induce-genotoxic-damage-both- PMID:  Bioelectromagnetics. 2005 Apr ;26(3):173-84. PMID: 15768430 Abstract Title:  915 MHz microwaves and 50 Hz magnetic field affect chromatin conformation and 53BP1 foci in human lymphocytes from hypersensitive and healthy persons. Abstract:  We used exposure to microwaves from a global system for mobile communication (GSM) mobile phone (915 MHz, specific absorption rate (SAR) 37 mW/kg) and power frequency magnetic field (50 Hz, 15 muT peak value) to investigate the response of lymphocytes from healthy subjects and from persons reporting hypersensitivity to electromagnetic field (EMF). The hypersensitive and healthy donors were matched by gender and age and the data were analyzed blind to treatment condition. The changes in chromatin conformation were measured with the method of anomalous viscosity time dependencies (AVTD). 53BP1 protein, which has been shown to colocalize in foci with DNA double strand breaks (DSBs), was analyzed by immunostaining in situ. Exposure at room temperature to either 915 MHz or 50 Hz resulted in significant condensation of chromatin, shown as AVTD changes, which was similar to the effect of heat shock at 41 degrees C. No significant differences in responses between normal and hypersensitive subjects were detected. Neither 915 MHz nor 50 Hz exposure induced 53BP1 foci. On the contrary, a distinct decrease in background level of 53BP1 signaling was observed upon these exposures as well as after heat shock treatments. This decrease correlated with the AVTD data and may indicate decrease in accessibility of 53BP1 to antibodies because of stress-induced chromatin condensation. Apoptosis was determined by morphological changes and by apoptotic fragmentation of DNA as analyzed by pulsed-field gel electrophoresis (PFGE). No apoptosis was induced by exposure to 50 Hz and 915 MHz microwaves. In conclusion, 50 Hz magnetic field and 915 MHz microwaves under specified conditions of exposure induced comparable responses in lymphocytes from healthy and hypersensitive donors that were similar but not identical to stress response induced by heat shock. <p><a href="https://greenmedinfo.com/article/50-hz-magnetic-fields-and-915-mhz-microwaves-can-induce-genotoxic-damage-both-" target="_blank">read more</a></p> https://greenmedinfo.com/article/50-hz-magnetic-fields-and-915-mhz-microwaves-can-induce-genotoxic-damage-both-#comments DNA damage Electromagnetic Field Harms Electromagnetic Radiation Electromagnetic Hypersensitivity Radio Frequency Electromagnetic Radiation Exposure Human In Vitro Wed, 25 Sep 2019 14:55:32 +0000 greenmedinfo 197194 at https://greenmedinfo.com A review of electromagnetic field induced biological effects in humans. https://greenmedinfo.com/article/review-electromagnetic-field-induced-biological-effects-humans PMID:  Przegl Lek. 2015 ;72(11):636-41. PMID: 27012122 Abstract Title:  Electromagnetic field induced biological effects in humans. Abstract:  Exposure to artificial radio frequency electromagnetic fields (EMFs) has increased significantly in recent decades. Therefore, there is a growing scientific and social interest in its influence on health, even upon exposure significantly below the applicable standards. The intensity of electromagnetic radiation in human environment is increasing and currently reaches astronomical levels that had never before experienced on our planet. The most influential process of EMF impact on living organisms, is its direct tissue penetration. The current established standards of exposure to EMFs in Poland and in the rest of the world are based on the thermal effect. It is well known that weak EMF could cause all sorts of dramatic non-thermal effects in body cells, tissues and organs. The observed symptoms are hardly to assign to other environmental factors occurring simultaneously in the human environment. Although, there are still ongoing discussions on non-thermal effects of EMF influence, on May 31, 2011--International Agency for Research on Cancer (IARC)--Agenda of World Health Organization (WHO) has classified radio electromagnetic fields, to a category 2B as potentially carcinogenic. Electromagnetic fields can be dangerous not only because of the risk of cancer, but also other health problems, including electromagnetic hypersensitivity (EHS). Electromagnetic hypersensitivity (EHS) is a phenomenon characterized by the appearance of symptoms after exposure of people to electromagnetic fields, generated by EHS is characterized as a syndrome with a broad spectrum of non-specific multiple organ symptoms including both acute and chronic inflammatory processes located mainly in the skin and nervous systems, as well as in respiratory, cardiovascular systems, and musculoskeletal system. WHO does not consider the EHS as a disease-- defined on the basis of medical diagnosis and symptoms associated with any known syndrome. The symptoms may be associated with a single source of EMF or be derived from a combination of many sources. Reported symptoms associated with electromagnetic fields are characterized by the overlapping effect with other individuals with these symptoms exhibited a broad spectrum of clinical manifestations, related to exposure to a single or multiple sources of EMF. The phenomenon of electromagnetic hypersensitivity in the form of dermatological disease is associated with mastocytosis. The biopsies taken from skin lesions of patients with EHS indicated on infiltration of the skin layers of the epidermis with mastocytes and their degranulation, as well as on release anaphylactic reaction mediators such as histamine, chymase and tryptase. The number of people suffering from EHS in the world is growing describing themselves as severely dysfunctional, showing multi organ non-specific symptoms upon exposure to low doses of electromagnetic radiation, often associated with hypersensitivity to many chemical agents (Multiple Chemical Sensitivity-MCS) and/or other environmental intolerances (Sensitivity Related Illness-SRI). <p><a href="https://greenmedinfo.com/article/review-electromagnetic-field-induced-biological-effects-humans" target="_blank">read more</a></p> https://greenmedinfo.com/article/review-electromagnetic-field-induced-biological-effects-humans#comments Electromagnetic Field Harms Electromagnetic Hypersensitivity Review Tue, 25 Sep 2018 21:39:34 +0000 greenmedinfo 171253 at https://greenmedinfo.com According to this animal study, electromagnetic radiation may inhibit autophagy in certain brain regions. https://greenmedinfo.com/article/according-animal-study-electromagnetic-radiation-may-inhibit-autophagy-certain PMID:  Toxicol Ind Health. 2018 Jan ;34(1):23-35. Epub 2017 Nov 22. PMID: 29166827 Abstract Title:  Exposure to 835 MHz radiofrequency electromagnetic field induces autophagy in hippocampus but not in brain stem of mice. Abstract:  The exploding popularity of mobile phones and their close proximity to the brain when in use has raised public concern regarding possible adverse effects from exposure to radiofrequency electromagnetic fields (RF-EMF) on the central nervous system. Numerous studies have suggested that RF-EMF emitted by mobile phones can influence neuronal functions in the brain. Currently, there is still very limited information on what biological mechanisms influence neuronal cells of the brain. In the present study, we explored whether autophagy is triggered in the hippocampus or brain stem after RF-EMF exposure. C57BL/6 mice were exposed to 835 MHz RF-EMF with specific absorption rates (SAR) of 4.0 W/kg for 12 weeks; afterward, the hippocampus and brain stem of mice were dissected and analyzed. Quantitative real-time polymerase chain reaction (qRT-PCR) analysis demonstrated that several autophagic genes, which play key roles in autophagy regulation, were significantly upregulated only in the hippocampus and not in the brain stem. Expression levels of LC3B-II protein and p62, crucial autophagic regulatory proteins, were significantly changed only in the hippocampus. In parallel, transmission electron microscopy (TEM) revealed an increase in the number of autophagosomes and autolysosomes in the hippocampal neurons of RF-EMF-exposed mice. The present study revealed that autophagy was induced in the hippocampus, not in the brain stem, in 835 MHz RF-EMF with an SAR of 4.0 W/kg for 12 weeks. These results could suggest that among the various adaptation processes to the RF-EMF exposure environment, autophagic degradation is one possible mechanism in specific brain regions. <p><a href="https://greenmedinfo.com/article/according-animal-study-electromagnetic-radiation-may-inhibit-autophagy-certain" target="_blank">read more</a></p> https://greenmedinfo.com/article/according-animal-study-electromagnetic-radiation-may-inhibit-autophagy-certain#comments Cell Phone Exposure Electromagnetic Field Harms Electromagnetic Radiation Microwave Radiation Mobile Phone Radiation Autophagy Inhibitors Brain Function Cell Phones electromagnetic fields electromagnetic frequencies Electromagnetic Hypersensitivity electromagnetic radiation EMF Radio Frequency Electromagnetic Radiation Exposure Animal Study Sat, 03 Aug 2019 00:53:14 +0000 greenmedinfo 192730 at https://greenmedinfo.com Average daily phone call duration is associated with severity of headaches in both men and women. https://greenmedinfo.com/article/average-daily-phone-call-duration-associated-severity-headaches-both-men-and-w PMID:  Environ Health Toxicol. 2016 ;31:e2016022. Epub 2016 Oct 26. PMID: 27788568 Abstract Title:  A cross-sectional study of the association between mobile phone use and symptoms of ill health. Abstract:  OBJECTIVES: This study analyzed the associations between mobile phone call frequency and duration with non-specific symptoms.METHODS: This study was conducted with a population group including 532 non-patient adults established by the Korean Genome and Epidemiology Study. The pattern of phone call using a mobile phone was investigated through face-to-face interview. Structured methods applied to quantitatively assess health effects are Headache Impact Test-6 (HIT-6), Psychosocial Well-being Index-Short Form, Beck Depression Inventory, Korean-Instrumental Activities of Daily Living, Perceived Stress Scale (PSS), Pittsburgh Sleep Quality Index, and 12-item Short Form Health Survey where a higher score represents a higher greater health effect.RESULTS: The average daily phone call frequency showed a significant correlation with the PSS score in female subjects. Increases in the average duration of one phone call were significantly correlated with increases in the severity of headaches in both sexes. The mean (standard deviation) HIT-6 score in the subgroup of subjects whose average duration of one phone call was five minutes or longer was 45.98 (8.15), as compared with 42.48 (7.20) in those whose average duration of one phone call was<p><a href="https://greenmedinfo.com/article/average-daily-phone-call-duration-associated-severity-headaches-both-men-and-w" target="_blank">read more</a></p> https://greenmedinfo.com/article/average-daily-phone-call-duration-associated-severity-headaches-both-men-and-w#comments Headache Cell Phone Exposure Electromagnetic Field Harms Electromagnetic Radiation Mobile Phone Radiation Cell Phones electromagnetic fields Electromagnetic Hypersensitivity electromagnetic radiation EMF Human Study Wed, 31 Jul 2019 23:15:06 +0000 greenmedinfo 192427 at https://greenmedinfo.com Cell phone users experience subjective symptoms, like headaches and fatigue, associated with intensity of use. https://greenmedinfo.com/article/cell-phone-users-experience-subjective-symptoms-headaches-and-fatigue-associat PMID:  Int J Occup Med Environ Health. 2014 Apr ;27(2):293-303. Epub 2014 Apr 1. PMID: 24692074 Abstract Title:  The risk of subjective symptoms in mobile phone users in Poland--an epidemiological study. Abstract:  OBJECTIVES: To assess the type and incidence of subjective symptoms related to the use of mobile phones in Polish users.MATERIAL AND METHODS: The study was conducted in 2005 using a questionnaire survey. Although it has been quite a long time, up to now, no such data have been published for Poland. The questionnaire consisted of 53 questions concerning sex, age, education, general health, characteristics of a mobile phone (hand-held, loud-speaking unit) as well as the habits associated with its use (frequency and duration of calls, text messages, etc.) and complaints associated with using a mobile phone.RESULTS: As many as 1800 questionnaires were sent. The response was obtained from 587 subjects aged 32.6± 11.3 (48.9% women, 51.1% men); the age did not differ significantly between men and women. The subjects owned a cell phone for an average of 3 years. Majority of the respondents used the phone intensively, i.e. daily (74%) or almost daily (20%). Headaches were reported significantly more often bythe people who talked frequently and long in comparison with other users (63.2% of the subjects, p = 0.0029), just like the symptoms of fatigue (45%, p = 0.013). Also, the feeling of warmth around the ear and directly to the auricle was reported significantly more frequently by the intensive mobilephone users, compared with other mobile phone users (47.3%, p = 0.00004 vs. 44.6%, p = 0.00063, respectively). Most symptoms appeared during or immediately after a call and disappeared within 2 h after the call. Continuous headache, persisting for longer than 6 h since the end of a call, was reported by 26% of the subjects.CONCLUSIONS: Our results show that the mobile phone users may experience subjective symptoms, the intensity of which depends on the intensity of use of mobile phones. <p><a href="https://greenmedinfo.com/article/cell-phone-users-experience-subjective-symptoms-headaches-and-fatigue-associat" target="_blank">read more</a></p> https://greenmedinfo.com/article/cell-phone-users-experience-subjective-symptoms-headaches-and-fatigue-associat#comments Fatigue Headaches Cell Phone Exposure Electromagnetic Field Harms Electromagnetic Radiation Mobile Phone Radiation Electromagnetic Hypersensitivity Radio Frequency Electromagnetic Radiation Exposure Human Study Mon, 16 Sep 2019 22:04:44 +0000 greenmedinfo 196587 at https://greenmedinfo.com Characteristics of perceived electromagnetic hypersensitivity in the general population. https://greenmedinfo.com/article/characteristics-perceived-electromagnetic-hypersensitivity-general-population PMID:  Scand J Psychol. 2018 Aug ;59(4):422-427. Epub 2018 May 9. PMID: 29741795 Abstract Title:  Characteristics of perceived electromagnetic hypersensitivity in the general population. Abstract:  Health problems evoked in the presence of electrical equipment is a concern, calling for better understanding for characteristics of electromagnetic hypersensitivity (EHS) in the general population. The present study investigated demographics, lifestyle factors, frequency and duration, coping strategies, proportion meeting clinical criteria for intolerance attributed to electromagnetic fields (EMF) and comorbidity. Using data from a large-scale population-based questionnaire study, we investigated persons with self-reported (n = 91) EHS in comparison to referents (n = 3,250). Middle age, female sex and poor perceived health was found to be associated with EHS. More than 50% in the EHS group reported having EMF-related symptoms more often than once a week, and the mean number of years experiencing EHS was 10.5. More than half of the EHS group reported that their symptoms started after a high-dose or long-term EMF exposure, that they actively tried to avoid EMF sources and that they mostly could affect the EMF environment. A minority of the EHS group had sought medical attention, been diagnosed by a physician orreceived treatment. Exhaustion syndrome, anxiety disorder, back/joint/muscle disorder, depression, functional somatic syndrome and migraine were comorbid with EHS. The results provide ground for future study of these characteristic features being risk factors for development of EHS and or consequences of EHS. <p><a href="https://greenmedinfo.com/article/characteristics-perceived-electromagnetic-hypersensitivity-general-population" target="_blank">read more</a></p> https://greenmedinfo.com/article/characteristics-perceived-electromagnetic-hypersensitivity-general-population#comments Electrosensitivity Electromagnetic Field Harms Electromagnetic Radiation Electromagnetic Hypersensitivity Human Study Thu, 08 Aug 2019 19:10:50 +0000 greenmedinfo 193217 at https://greenmedinfo.com Chronic 2450 MHz RF-EMF fields exposure leads to adverse effects on the liver including occasional necrosis and inflammatory infiltrate. https://greenmedinfo.com/article/chronic-2450-mhz-rf-emf-fields-exposure-leads-adverse-effects-liver-including- PMID:  J Toxicol Environ Health A. 2015 ;78(6):353-6. PMID: 25734762 Abstract Title:  Structural and ultrastructural study of rat liver influenced by electromagnetic radiation. Abstract:  Mobile communication systems are undoubtedly an environmental source of electromagnetic radiation (EMR). There is an increasing concern regarding the interactions of EMR with the humans. The aim of this study was to examine the effects of EMR on Wistar rat liver. Mature rats were exposed to electromagnetic field of frequency 2.45 GHz and mean power density of 2.8 mW/cm2 for 3 h/d for 3 wk. Samples of the liver were obtained 3 h after the last irradiation and processed histologically for light and transmission electron microscopy. Data demonstrated the presence of moderate hyperemia, dilatation of liver sinusoids, and small inflammatory foci in the center of liver lobules. Structure of hepatocytes was not altered and all described changes were classified as moderate. Electron microscopy of hepatocytes revealed vesicles of different sizes and shapes, lipid droplets, and proliferation of smooth endoplasmic reticulum. Occasionally necrotizing hepatocytes were observed. Our observations demonstrate that EMR exposure produced adverse effects on rat liver. <p><a href="https://greenmedinfo.com/article/chronic-2450-mhz-rf-emf-fields-exposure-leads-adverse-effects-liver-including-" target="_blank">read more</a></p> https://greenmedinfo.com/article/chronic-2450-mhz-rf-emf-fields-exposure-leads-adverse-effects-liver-including-#comments Cell Phone Exposure Electromagnetic Field Harms Electromagnetic Radiation Electromagnetic Radiation: 2.4 GHz Hepatotoxic Inflammatory Microwave Radiation Mobile Phone Radiation Necrotic electromagnetic fields electromagnetic frequencies Electromagnetic Hypersensitivity electromagnetic radiation EMF Radio Frequency Electromagnetic Radiation Exposure Animal Study Fri, 02 Aug 2019 23:20:40 +0000 greenmedinfo 192699 at https://greenmedinfo.com Currently, there is insufficient data to draw firm conclusions about health effects from long-term low-level radiofrequency electromagnetic field exposure typically occurring in the everyday environment. https://greenmedinfo.com/article/currently-there-insufficient-data-draw-firm-conclusions-about-health-effects-l PMID:  Bull World Health Organ. 2010 Dec 1 ;88(12):887-896F. Epub 2010 Oct 5. PMID: 21124713 Abstract Title:  Systematic review on the health effects of exposure to radiofrequency electromagnetic fields from mobile phone base stations. Abstract:  OBJECTIVE: to review and evaluate the recent literature on the health effects of exposure to mobile phone base station (MPBS) radiation.METHODS: we performed a systematic review of randomized human trials conducted in laboratory settings and of epidemiological studies that investigated the health effects of MPBS radiation in the everyday environment.FINDINGS: we included in the analysis 17 articles that met our basic quality criteria: 5 randomized human laboratory trials and 12 epidemiological studies. The majority of the papers (14) examined self-reported non-specific symptoms of ill-health. Most of the randomized trials did not detect any association between MPBS radiation and the development of acute symptoms during or shortly after exposure. The sporadically observed associations did not show a consistent pattern with regard to symptoms or types of exposure. We also found that the more sophisticated the exposure assessment, the less likely it was that an effect would be reported. Studies on health effects other than non-specific symptoms and studies on MPBS exposure in children were scarce.CONCLUSION: the evidence for a missing relationship between MPBS exposure up to 10 volts per metre and acute symptom development can be considered strong because it is based on randomized, blinded human laboratory trials. At present, there is insufficient data to draw firm conclusions about health effects from long-term low-level exposure typically occurring in the everyday environment. <p><a href="https://greenmedinfo.com/article/currently-there-insufficient-data-draw-firm-conclusions-about-health-effects-l" target="_blank">read more</a></p> https://greenmedinfo.com/article/currently-there-insufficient-data-draw-firm-conclusions-about-health-effects-l#comments Radiation Induced Illness Electromagnetic Field Harms Electromagnetic Radiation Electromagnetic Hypersensitivity Radio Frequency Electromagnetic Radiation Exposure Review Wed, 25 Sep 2019 13:43:43 +0000 greenmedinfo 197188 at https://greenmedinfo.com Dirty electricity raises plasma glucose in electrohypersensitive, diabetic individuals. https://greenmedinfo.com/article/dirty-electricity-raises-plasma-glucose-electrohypersensitive-diabetic-individ PMID:  Electromagn Biol Med. 2008 ;27(2):135-46. PMID: 18568931 Abstract Title:  Dirty electricity elevates blood sugar among electrically sensitive diabetics and may explain brittle diabetes. Abstract:  Transient electromagnetic fields (dirty electricity), in the kilohertz range on electrical wiring, may be contributing to elevated blood sugar levels among diabetics and pre-diabetics. By closely following plasma glucose levels in four Type 1 and Type 2 diabetics, we find that they responded directly to the amount of dirty electricity in their environment. In an electromagnetically clean environment, Type 1 diabetics require less insulin and Type 2 diabetics have lower levels of plasma glucose. Dirty electricity, generated by electronic equipment and wireless devices, is ubiquitous in the environment. Exercise on a treadmill, which produces dirty electricity, increases plasma glucose. These findings may explain why brittle diabetics have difficulty regulating blood sugar. Based on estimates of people who suffer from symptoms of electrical hypersensitivity (3-35%), as many as 5-60 million diabetics worldwide may be affected. Exposure to electromagnetic pollution in its various forms may account for higher plasma glucose levels and may contribute to the misdiagnosis of diabetes. Reducing exposure to electromagnetic pollution by avoidance or with specially designed GS filters may enable some diabetics to better regulate their blood sugar with less medication and borderline or pre-diabetics to remain non diabetic longer. <p><a href="https://greenmedinfo.com/article/dirty-electricity-raises-plasma-glucose-electrohypersensitive-diabetic-individ" target="_blank">read more</a></p> https://greenmedinfo.com/article/dirty-electricity-raises-plasma-glucose-electrohypersensitive-diabetic-individ#comments Diabetes Mellitus: Type 2 Electromagnetic Field Harms Electromagnetic Radiation Electromagnetic Hypersensitivity Human Study Mon, 04 Nov 2019 19:46:11 +0000 greenmedinfo 200922 at https://greenmedinfo.com Effective control of environmental Electrosmog immunomodulation may soon become necessary for successful therapy of autoimmune disease. https://greenmedinfo.com/article/effective-control-environmental-electrosmog-immunomodulation-may-soon-become-n PMID:  Immunol Res. 2017 02 ;65(1):129-135. PMID: 27412293 Abstract Title:  Electrosmog and autoimmune disease. Abstract:  Studies in mice have shown that environmental electromagnetic waves tend to suppress the murine immune system with a potency similar to NSAIDs, yet the nature of any Electrosmog effects upon humans remains controversial. Previously, we reported how the human Vitamin-D receptor (VDR) and its ligand, 1,25-dihydroxyvitamin-D (1,25-D), are associated with many chronic inflammatory and autoimmune diseases. We have shown how olmesartan, a drug marketed for mild hypertension, acts as a high-affinity partial agonist for the VDR, and that it seems to reverse disease activity resulting from VDR dysfunction. We here report that structural instability of the activated VDR becomes apparent when observing hydrogen bond behavior with molecular dynamics, revealing that the VDR pathway exhibits a susceptibility to Electrosmog. Further, we note that characteristic modes of instability lie in the microwave frequency range, which is currently populated by cellphone and WiFi communication signals, and that the susceptibility is ligand dependent. A case series of 64 patient-reported outcomes subsequent to use of a silver-threaded cap designed to protect the brain and brain stem from microwave Electrosmog resulted in 90 % reporting&quot;definite&quot;or&quot;strong&quot;changes in their disease symptoms. This is much higher than the 3-5 % rate reported for electromagnetic hypersensitivity in a healthy population and suggests that effective control of environmental Electrosmog immunomodulation may soon become necessary for successful therapy of autoimmune disease. <p><a href="https://greenmedinfo.com/article/effective-control-environmental-electrosmog-immunomodulation-may-soon-become-n" target="_blank">read more</a></p> https://greenmedinfo.com/article/effective-control-environmental-electrosmog-immunomodulation-may-soon-become-n#comments Autoimmune Diseases Electromagnetic Field Harms Mobile Phone Radiation Wi-Fi Radiation Electromagnetic Hypersensitivity Risk Factors Human Study Tue, 25 Sep 2018 21:18:32 +0000 greenmedinfo 171250 at https://greenmedinfo.com Electrohypersensitive individuals have high cutaneous immunoreactivity to electromagnetic fields and governments should acknowledge this and make attempts to accomodate the environment to electrohypersensitive individuals, like any other disability. https://greenmedinfo.com/article/electrohypersensitive-individuals-have-high-cutaneous-immunoreactivity-electro n/a PMID:  Rev Environ Health. 2015 ;30(4):311-21. PMID: 26613327 Abstract Title:  Electrohypersensitivity: a functional impairment due to an inaccessible environment. Abstract:  In Sweden, electrohypersensitivity is recognized as a functional impairment which implies only the environment as the culprit. The Swedish view provides persons with this impairment a maximal legal protection, it gives them the right to get accessibility measures for free, as well as governmental subsidies and municipality economic support, and to provide them with special Ombudsmen (at the municipality, the EU, and the UN level, respectively), the right and economic means to form disability organizations and allow these to be part of national and international counterparts, all with the simple and single aim to allow persons with the functional impairment electrohypersensitivity to live an equal life in a society based on equality. They are not seen as patients, the do not have an overriding medical diagnosis, but the &#039;patient&#039; is only the inferior and potentially toxic environment. This does not mean that a subjective symptom of a functionally impaired can not be treated by a physician, as well as get sick-leave from their workplace as well as economic compensation, and already in the year 2000 such symptoms were identified in the Internal Code of Diagnoses, version 10 (ICD-10; R68.8/now W90), and have been since. But the underlying cause still remains only the environment. https://greenmedinfo.com/article/electrohypersensitive-individuals-have-high-cutaneous-immunoreactivity-electro#comments 5G Millimeter Wave Radiation Electromagnetic Field Harms Electromagnetic Radiation Electromagnetic Hypersensitivity Environmental Review Wed, 16 Oct 2019 20:06:45 +0000 greenmedinfo 199175 at https://greenmedinfo.com Electrohypersensitive persons in this study were suffering not only from their symptoms, but also from economical and social problems. https://greenmedinfo.com/article/electrohypersensitive-persons-study-were-suffering-not-only-their-symptoms-als PMID:  Pathophysiology. 2012 Apr ;19(2):95-100. Epub 2012 Mar 27. PMID: 22458999 Abstract Title:  Reported functional impairments of electrohypersensitive Japanese: A questionnaire survey. Abstract:  An increasing number of people worldwide complain that they have become electromagnetic hypersensitive (EHS). We conducted a questionnaire survey of EHS persons in Japan. The aim was to identify electromagnetic fields (EMF) and plausible EMF sources that caused their symptoms. Postal questionnaires were distributed via a self-help group, and 75 participants (95% women) responded. Reported major complaints were&quot;fatigue/tiredness&quot;(85%),&quot;headache&quot;,&quot;concentration, memory, and thinking&quot;difficulty (81%, respectively). Seventy-two per cent used some form of complementary/alternative therapy. The most plausible trigger of EHS onset was a mobile phone base station or personal handy-phone system (37%). Sixty-five percent experienced health problems to be due to the radiation from other passengers&#039; mobile phones in trains or buses, and 12% reported that they could not use public transportation at all. Fifty-three percent had a job before the onset, but most had lost their work and/or experienced a decrease in income. Moreover, 85.3% had to take measures to protect themselves from EMF, such as moving to low EMF areas, or buying low EMF electric appliances. EHS persons were suffering not only from their symptoms, but also from economical and social problems. <p><a href="https://greenmedinfo.com/article/electrohypersensitive-persons-study-were-suffering-not-only-their-symptoms-als" target="_blank">read more</a></p> https://greenmedinfo.com/article/electrohypersensitive-persons-study-were-suffering-not-only-their-symptoms-als#comments Cognitive Decline/Dysfunction Fatigue Headache Memory Disorders Electromagnetic Field Harms Electromagnetic Radiation Microwave Radiation Mobile Phone Radiation Electromagnetic Hypersensitivity EMF Human Study Thu, 15 Aug 2019 23:42:56 +0000 greenmedinfo 193867 at https://greenmedinfo.com Electrohypersensitivity may be diagnosable by MRI. https://greenmedinfo.com/article/electrohypersensitivity-may-be-diagnosable-mri PMID:  Rev Environ Health. 2017 Sep 26 ;32(3):291-299. PMID: 28678737 Abstract Title:  Functional brain MRI in patients complaining of electrohypersensitivity after long term exposure to electromagnetic fields. Abstract:  INTRODUCTION: Ten adult patients with electromagnetic hypersensitivity underwent functional magnetic resonance imaging (fMRI) brain scans. All scans were abnormal with abnormalities which were consistent and similar. It is proposed that fMRI brain scans be used as a diagnostic aid for determining whether or not a patient has electromagnetic hypersensitivity. Over the years we have seen an increasing number of patients who had developed multi system complaints after long term repeated exposure to electromagnetic fields (EMFs). These complaints included headaches, intermittent cognitive and memory problems, intermittent disorientation, and also sensitivity to EMF exposure. Regular laboratory tests were within normal limits in these patients. The patients refused to be exposed to radioactivity. This of course ruled out positron emission tomography (PET) and single-photon emission computed tomography (SPECT) brain scanning. This is why we ordered fMRI brain scans on these patients. We hoped that we could document objective abnormalities in these patients who had often been labeled as psychiatric cases.MATERIALS AND METHODS: Ten patients first underwent a regular magnetic resonance imaging (MRI) brain scan, using a 3 Tesla Siemens Verio MRI open system. A functional MRI study was then performed in the resting state using the following sequences: A three-dimensional, T1-weighted, gradient-echo (MPRAGE) Resting state network. The echo-planar imaging (EPI) sequences for this resting state blood oxygenation level dependent (BOLD) scan were then post processed on a 3D workstation and the independent component analysis was performed separating out the various networks. Arterial spin labeling. Tractography and fractional anisotropy.RESULTS: All ten patients had abnormal functional MRI brain scans. The abnormality was often described as hyper connectivity of the anterior component of the default mode in the medial orbitofrontal area. Other abnormalities were usually found. Regular MRI studies of the brain were mostly unremarkable in these patients.CONCLUSION: We propose that functional MRI studies should become a diagnostic aid when evaluating a patient who claims electrohypersensitivity (EHS) and has otherwise normal studies. Interestingly, the differential diagnosis for the abnormalities seen on the fMRI includes head injury. It turns out that many of our patients indeed had a history of head injury which was then followed sometime later by the development of EHS. Many of our patients also had a history of exposure to potentially neurotoxic chemicals, especially mold. Head injury and neurotoxic chemical exposure may make a patient more vulnerable to develop EHS. <p><a href="https://greenmedinfo.com/article/electrohypersensitivity-may-be-diagnosable-mri" target="_blank">read more</a></p> https://greenmedinfo.com/article/electrohypersensitivity-may-be-diagnosable-mri#comments Electromagnetic Field Harms Electromagnetic Radiation Electromagnetic Hypersensitivity Human Study Mon, 04 Nov 2019 13:56:49 +0000 greenmedinfo 200870 at https://greenmedinfo.com Electromagnetic hypersensitive individuals have altered glutathione and catalase activity along with a higher risk for polymorphisms in certain xenobiotic-metabolizing enzymes. https://greenmedinfo.com/article/electromagnetic-hypersensitive-individuals-have-altered-glutathione-and-catala PMID:  Mediators Inflamm. 2014 ;2014:924184. Epub 2014 Apr 9. PMID: 24812443 Abstract Title:  Metabolic and genetic screening of electromagnetic hypersensitive subjects as a feasible tool for diagnostics and intervention. Abstract:  Growing numbers of&quot;electromagnetic hypersensitive&quot;(EHS) people worldwide self-report severely disabling, multiorgan, non-specific symptoms when exposed to low-dose electromagnetic radiations, often associated with symptoms of multiple chemical sensitivity (MCS) and/or other environmental&quot;sensitivity-related illnesses&quot;(SRI). This cluster of chronic inflammatory disorders still lacks validated pathogenetic mechanism, diagnostic biomarkers, and management guidelines. We hypothesized that SRI, not being merely psychogenic, may share organic determinants of impaired detoxification of common physic-chemical stressors. Based on our previous MCS studies, we tested a panel of 12 metabolic blood redox-related parameters and of selected drug-metabolizing-enzyme gene polymorphisms, on 153 EHS, 147 MCS, and 132 control Italians, confirming MCS altered (P<p><a href="https://greenmedinfo.com/article/electromagnetic-hypersensitive-individuals-have-altered-glutathione-and-catala" target="_blank">read more</a></p> https://greenmedinfo.com/article/electromagnetic-hypersensitive-individuals-have-altered-glutathione-and-catala#comments Electromagnetic Field Harms Electromagnetic Radiation Electromagnetic Hypersensitivity Human Study Mon, 04 Nov 2019 15:14:01 +0000 greenmedinfo 200878 at https://greenmedinfo.com