Light-Emitting Diodes (LEDs) Therapy

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75 Diseases Researched for Light-Emitting Diodes (LEDs) Therapy
NameACCKFocus
Wound Healing1340Locked
Acne220Locked
Muscle Fatigue220Locked
Scars220Locked
Alzheimer's Disease213Locked
Dementia213Locked
Chemotherapy and Radiation Toxicity212Locked
Hyperbilirubinemia: Hereditary212Locked
Jaundice: Neonatal212Locked
Obesity212Locked
Oral Mucositis212Locked
Aging Skin211Locked
Athletic Performance: Recovery 110Locked
Dental Plaque110Locked
Dermatitis110Locked
Diabetes Mellitus: Type 2110Locked
Drug-Induced Toxicity: Methotrexate110Locked
Leukoplakia110Locked
Muscle Damage: Exercise-Induced110Locked
Muscle Soreness110Locked
Precancerous Conditions110Locked
Traumatic Brain Injury110Locked
Inflammation58Locked
Melanoma28Locked
Periodontal Diseases26Locked
Acinetobacter baumannii infection15Locked
Lymphoma15Locked
Tongue Cancer15Locked
Burns24Locked
Root Canal Therapy14Locked
Stroke: Ischemic24Locked
Brain Injury: Traumatic13Locked
Colon Cancer23Locked
Graft vs Host Disease13Locked
Leg Ulcer13Locked
Staphylococcus aureus: Methicillin-resistant (MRSA)33Locked
Asthma12Locked
Athletic Performance12Locked
Atopic Dermatitis12Locked
Burns: Severe12Locked
Cervical Cancer22Locked
Chemotherapy-Induced Toxicity: 5-fluorouracil 12Locked
Diabetic Complications12Locked
Fatigue12Locked
Fibrosarcoma12Locked
Formaldehyde Toxicity12Locked
Heart Failure12Locked
Hyperglycemia12Locked
Lung Inflammation12Locked
Oral Cancer22Locked
Oxidative Stress12Locked
Pain12Locked
Periodontitis12Locked
Skin Diseases22Locked
Stroke: Attenuation/Recovery 12Locked
Tendon Injury12Locked
Ultraviolet Radiation Induced Damage12Locked
Vitamin D Deficiency12Locked
Wounds and Injuries12Locked
Brain Inflammation 11Locked
Cancers: Drug Resistant11Locked
Cholangiocarcinoma11Locked
Diabetic Ulcer11Locked
Escherichia coli Infections11Locked
Eye Damage11Locked
Fibrosis11Locked
Foodborne Pathogens: Prevention/Food Preservation11Locked
Ischemia11Locked
Keloid11Locked
Leukemia: Acute promyelocytic leukemia 11Locked
Lymphoma: B-Cell11Locked
Neurologic Disorders11Locked
Pseudomonas aeruginosa11Locked
Psoriasis11Locked
Retinal Diseases11Locked

View the Evidence:
87 Abstracts with Light-Emitting Diodes (LEDs) Therapy Research

[+]

A muscular pre-conditioning regimen using LEDT before intense exercises could modulate metabolic and renal function to achieve better performance.Jun 30, 2015

Pubmed Data : Physiother Theory Pract. 2015 Jul ;31(5):354-61. Epub 2015 Jan 14. PMID: 25585514
Article Published Date : Jun 30, 2015
Study Type : Human Study
Additional Links
Therapeutic Actions : Exercise, Light-Emitting Diodes (LEDs) Therapy
[+]

A newly designed LED device was an effective treatment for moderate to severe acne vulgaris, with mild and reversible side effects.Jun 22, 2015

Pubmed Data : Photodiagnosis Photodyn Ther. 2015 Jun 23. Epub 2015 Jun 23. PMID: 26116283
Article Published Date : Jun 22, 2015
Study Type : Human Study
Additional Links
Diseases : Acne
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
[+]

Blue light phototherapy, using a narrow-band LED light source, appears to be a safe and effective additional therapy for mild to moderate acne.Dec 31, 2014

Pubmed Data : J Cosmet Laser Ther. 2015 ;17(4):170-6. Epub 2015 Feb 20. PMID: 25594129
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Diseases : Acne
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Curcumin has a potential to disaggregate oral plaque.Oct 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Photomed Laser Surg. 2014 Nov ;32(11):627-32. Epub 2014 Oct 24. PMID: 25343373
Article Published Date : Oct 31, 2014
Study Type : Human Study
Additional Links
Substances : Curcumin
Diseases : Dental Plaque
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
[+]

Early application of 830-nm LED-based photobiomodulation treatment significantly prevents hypertrophic scar formation.Aug 31, 2022

Pubmed Data : Lasers Med Sci. 2022 Sep 1. Epub 2022 Sep 1. PMID: 36045183
Article Published Date : Aug 31, 2022
Study Type : Human Study
Additional Links
Diseases : Scars
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions : Analgesics
Additional Keywords : Risk Reduction
[+]

Effects of LED photobiomodulation therapy on the subcutaneous fatty tissue of obese individuals.Sep 07, 2022

Pubmed Data : J Cosmet Laser Ther. 2022 Sep 8:1-7. Epub 2022 Sep 8. PMID: 36074934
Article Published Date : Sep 07, 2022
Study Type : Human Study
Additional Links
Diseases : Obesity
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Additional Keywords : Anti-Obesity Agents
[+]

Evening exposure to blue light stimulates the expression of the clock gene PER2 in humans.Jan 31, 2006

Pubmed Data : Eur J Neurosci. 2006 Feb ;23(4):1082-6. PMID: 16519674
Article Published Date : Jan 31, 2006
Study Type : Human Study
Additional Links
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions : PER2 Protein Expression Up-regulation
Additional Keywords : Circadian Rhythm, Dose Response, PER2 Protein
[+]

Home-type phototherapy units are as effective as CFP units in the treatment of neonatal hyperbilirubinemia.Mar 31, 2015

Pubmed Data : J Trop Pediatr. 2015 Apr ;61(2):113-8. Epub 2015 Jan 23. PMID: 25617633
Article Published Date : Mar 31, 2015
Study Type : Human Study
Additional Links
Diseases : Hyperbilirubinemia: Hereditary, Jaundice: Neonatal
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
[+]

LED therapy can be useful to reduce muscle damage, pain, and atrophy, as well as to increase muscle mass and recovery.Apr 14, 2016

Pubmed Data : Am J Phys Med Rehabil. 2016 Apr 15. Epub 2016 Apr 15. PMID: 27088469
Article Published Date : Apr 14, 2016
Study Type : Human Study
Additional Links
Diseases : Muscle Fatigue, Muscle Soreness
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Superoxide Dismutase Up-regulation
[+]

LED therapy prevented significant increases of creatine kinase in blood in athletes when applied before official volleyball matches.Apr 30, 2015

Pubmed Data : Lasers Med Sci. 2015 May ;30(4):1281-7. Epub 2015 Feb 27. PMID: 25722067
Article Published Date : Apr 30, 2015
Study Type : Human Study
Additional Links
Diseases : Athletic Performance: Recovery , Muscle Damage: Exercise-Induced
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
[+]

LED therapy prior to radiation therapy might be effective in decreasing the incidence of radiation-induced skin toxicity in breast cancer patients.May 31, 2017

Pubmed Data : Strahlenther Onkol. 2017 Jun ;193(6):491-498. Epub 2017 Feb 27. PMID: 28243723
Article Published Date : May 31, 2017
Study Type : Human Study
Additional Links
Diseases : Chemotherapy and Radiation Toxicity, Dermatitis
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions : Radioprotective
[+]

Light-emitting diode based LLLT treatment suppressed the formation of scars after thyroidectomy.Mar 31, 2016

Pubmed Data : Dermatol Surg. 2016 Apr ;42(4):526-34. PMID: 26981718
Article Published Date : Mar 31, 2016
Study Type : Human Study
Additional Links
Diseases : Scars, Wound Healing
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
[+]

Light-emitting diode therapy had a positive effect on performance when irradiating 6 points on the superficial quadriceps.Jan 31, 2017

Pubmed Data : J Strength Cond Res. 2017 Feb ;31(2):395-402. PMID: 27359205
Article Published Date : Jan 31, 2017
Study Type : Human Study
Additional Links
Diseases : Muscle Fatigue
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
[+]

Light-emitting diode therapy in combination with moderate exercise acutely decreased the glucose levels in men with T2DM.Jan 31, 2019

Pubmed Data : Complement Ther Med. 2019 Feb ;42:178-183. Epub 2018 Nov 15. PMID: 30670240
Article Published Date : Jan 31, 2019
Study Type : Human Study
Additional Links
Diseases : Diabetes Mellitus: Type 2
Therapeutic Actions : Exercise, Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions : Hypoglycemic Agents
[+]

Light-emitting diodes (LED) therapy has a skin rejuvenating effect in human subjects.Jul 27, 2007

Pubmed Data : J Photochem Photobiol B. 2007 Jul 27;88(1):51-67. Epub 2007 May 1. PMID: 17566756
Article Published Date : Jul 27, 2007
Study Type : Human Study
Additional Links
Diseases : Aging Skin
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
[+]

Photobiomodulation shows potential for home treatment of patients with dementia and Alzheimer's disease.Feb 09, 2017

Pubmed Data : Photomed Laser Surg. 2017 Feb 10. Epub 2017 Feb 10. PMID: 28186867
Article Published Date : Feb 09, 2017
Study Type : Human Study
Additional Links
Diseases : Alzheimer's Disease, Dementia
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
[+]

Photodynamic therapy appears to be a feasible alternative to conventional therapy for oral premalignant lesions.Dec 31, 2015

Pubmed Data : J Lasers Med Sci. 2016 ;7(1):30-6. Epub 2016 Jan 7. PMID: 27330695
Article Published Date : Dec 31, 2015
Study Type : Human Study
Additional Links
Diseases : Leukoplakia, Precancerous Conditions
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy, Photodynamic therapy
[+]

The effect of combined red, blue, and near-infrared light-emitting diode (LED) photobiomodulation therapy on speed of wound healing after superficial ablative fractional resurfacing.Mar 26, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Lasers Med Sci. 2024 Mar 27 ;39(1):94. Epub 2024 Mar 27. PMID: 38532146
Article Published Date : Mar 26, 2024
Study Type : Human Study
Additional Links
Diseases : Wound Healing
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
[+]

These findings suggest that light-emitting diode therapy has similar effects to low-level laser therapy to avoid and treat oral mucositis.Apr 23, 2021

Pubmed Data : Support Care Cancer. 2021 Apr 24. Epub 2021 Apr 24. PMID: 33893842
Article Published Date : Apr 23, 2021
Study Type : Human Study
Additional Links
Diseases : Drug-Induced Toxicity: Methotrexate, Oral Mucositis
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy, Photobiomodulation
Pharmacological Actions : Chemoprotective Agents
Problem Substances : Methotrexate
[+]

Transcranial LED treatment improved sleep and led to fewer post-traumatic stress disorder symptoms.May 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Neurotrauma. 2014 Jun 1 ;31(11):1008-17. Epub 2014 May 8. PMID: 24568233
Article Published Date : May 31, 2014
Study Type : Human Study
Additional Links
Diseases : Traumatic Brain Injury
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
[+]

Blue LED irradiation induces apoptotic cell death by activating the mitochondria-mediated pathway and reduces the early growth rate of melanoma cells.Dec 31, 2014

Pubmed Data : J Photochem Photobiol B. 2015 Jan ;142:197-203. Epub 2014 Dec 12. PMID: 25550119
Article Published Date : Dec 31, 2014
Study Type : Human In Vitro
Additional Links
Diseases : Melanoma
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions : Antiproliferative , Apoptotic, Chemopreventive, Tumor Suppressor Protein p53 Upregulation
[+]

HMME combined with green light-emitting diode irradiation results in efficient apoptosis on human tongue squamous cell carcinoma.Aug 31, 2015

Pubmed Data : Lasers Med Sci. 2015 Sep ;30(7):1941-8. Epub 2015 Jul 26. PMID: 26210547
Article Published Date : Aug 31, 2015
Study Type : Human In Vitro
Additional Links
Diseases : Tongue Cancer
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy, Photodynamic therapy
[+]

Irradiation with blue LED light induced apoptotic cell death through autophagosome activation in RAMOS cells.Feb 29, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Data Brief. 2016 Mar ;6:630-3. Epub 2016 Jan 15. PMID: 26909378
Article Published Date : Feb 29, 2016
Study Type : Human In Vitro
Additional Links
Diseases : Lymphoma
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions : Apoptotic
[+]

LED irradiation promoted elastin gene expression more in elderly than in younger adults.Mar 31, 2016

Pubmed Data : J Biol Regul Homeost Agents. 2016 Apr-Jun;30(2 Suppl 1):161-7. PMID: 27469564
Article Published Date : Mar 31, 2016
Study Type : Human In Vitro
Additional Links
Diseases : Periodontal Diseases
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Additional Keywords : Gene Expression Regulation
[+]

This represents the first conclusive example of a direct role for the photodynamic therapy in breaking antibiotic resistance.May 31, 2017

Pubmed Data : Photodiagnosis Photodyn Ther. 2017 Jun ;18:1-5. Epub 2017 Jan 12. PMID: 28088439
Article Published Date : May 31, 2017
Study Type : Human In Vitro
Additional Links
Diseases : Acinetobacter baumannii infection
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions : Antimicrobial
[+]

Photodynamic therapy in root canal disinfection: A case series and mini-review.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Lasers Med Sci. 2022 ;13:e19. Epub 2022 Apr 29. PMID: 35996480
Article Published Date : Dec 31, 2021
Study Type : Human: Case Report, Review
Additional Links
Diseases : Root Canal Therapy
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy, Photodynamic therapy
Pharmacological Actions : Dental Disinfectants
[+]

Blue light promotes vitamin C-mediated ferroptosis of melanoma through specifically upregulating transporter SVCT2 and generating Fe2.May 30, 2023

Pubmed Data : Biomaterials. 2023 May 31 ;299:122186. Epub 2023 May 31. PMID: 37276798
Article Published Date : May 30, 2023
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Vitamin C
Diseases : Melanoma
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions : Chemopreventive
[+]

Irradiation with LED is a novel method of treatment of chronic wounds. Aug 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Indian J Plast Surg. 2014 Sep-Dec;47(3):432-5. PMID: 25593435
Article Published Date : Aug 31, 2014
Study Type : Human: Case Report
Additional Links
Diseases : Leg Ulcer, Wound Healing
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
[+]

Photobiomodulation therapy alleviates tissue fibroses associated with chronic graft-versus-host disease.Oct 18, 2017

Pubmed Data : Photomed Laser Surg. 2017 Oct 19. Epub 2017 Oct 19. PMID: 29053051
Article Published Date : Oct 18, 2017
Study Type : Human: Case Report
Additional Links
Diseases : Graft vs Host Disease
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy, Photobiomodulation
[+]

Transcranial LED therapy increased the cerebral blood flow in an elderly women.Dec 31, 2014

Pubmed Data : Lasers Med Sci. 2015 Jan ;30(1):339-46. Epub 2014 Oct 3. PMID: 25277249
Article Published Date : Dec 31, 2014
Study Type : Human: Case Report
Additional Links
Diseases : Alzheimer's Disease, Dementia
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Additional Keywords : Significant Treatment Outcome
[+]

Two cases of improved cognitive function After transcranial, light-emitting diode treatments in chronic, traumatic brain injury.Dec 23, 2010

Pubmed Data : Photomed Laser Surg. 2010 Dec 23. Epub 2010 Dec 23. PMID: 21182447
Article Published Date : Dec 23, 2010
Study Type : Human: Case Report
Additional Links
Diseases : Brain Injury: Traumatic
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
[+]

A combination of 660nm and 890nm LEDs significantly promoted the healing of skin wounds in undernourished rats.Oct 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : An Bras Dermatol. 2014 Nov-Dec;89(6):899-904. PMID: 25387494
Article Published Date : Oct 31, 2014
Study Type : Animal Study
Additional Links
Diseases : Wound Healing
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy, Photodynamic therapy
[+]

Blue LED irradiation inhibits cancer cell migration and invasion in vitro and in vivo.Jan 17, 2017

Pubmed Data : J Cell Physiol. 2017 Jan 18. Epub 2017 Jan 18. PMID: 28098340
Article Published Date : Jan 17, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Diseases : Colon Cancer, Fibrosarcoma
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions : Anti-metastatic, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]

Combinational therapy of LED and water bath might be used as a steroid-free alternative therapeutic strategy for the treatment of AD.Dec 31, 2015

Pubmed Data : Photodermatol Photoimmunol Photomed. 2016 Jan ;32(1):34-43. Epub 2015 Nov 6. PMID: 26479265
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Diseases : Atopic Dermatitis
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy, Spa Bathing
[+]

Combined blue and green spectra might be effective against neonatal hyperbilirubinemia.Jun 30, 2015

Pubmed Data : Early Hum Dev. 2015 Jul ;91(7):381-5. Epub 2015 May 15. PMID: 25984653
Article Published Date : Jun 30, 2015
Study Type : Animal Study
Additional Links
Diseases : Hyperbilirubinemia: Hereditary, Jaundice: Neonatal, Oxidative Stress
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy, Photodynamic therapy
[+]

Effects of photobiomodulation therapy with red LED on inflammatory cells during the healing of skin burns.Mar 01, 2022

Pubmed Data : Lasers Med Sci. 2022 Mar 2. Epub 2022 Mar 2. PMID: 35237887
Article Published Date : Mar 01, 2022
Study Type : Animal Study
Additional Links
Diseases : Burns, Wound Healing
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions : Anti-Inflammatory Agents
[+]

LED light irradiation at 660 nm accelerated palatal wound healing. Apr 30, 2015

Pubmed Data : J Periodontol. 2015 May ;86(5):674-81. Epub 2015 Jan 29. PMID: 25630628
Article Published Date : Apr 30, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Diseases : Wound Healing
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
[+]

LED photobiomodulation significantly reduced the presence of Aβ plaques and improved spatial memory and behavioural and motor skills in animals.Apr 30, 2017

Pubmed Data : Lasers Med Sci. 2017 May ;32(4):749-756. Epub 2017 Mar 2. PMID: 28255783
Article Published Date : Apr 30, 2017
Study Type : Animal Study
Additional Links
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions : Neuroprotective Agents
[+]

LED phototherapy with gelatin sponge promotes wound healing in mice.Jul 31, 2017

Pubmed Data : Photochem Photobiol. 2017 Aug 1. Epub 2017 Aug 1. PMID: 28763104
Article Published Date : Jul 31, 2017
Study Type : Animal Study
Additional Links
Diseases : Wound Healing
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
[+]

LED therapy can attenuate neuroinflammatory responses and tissue damage following ischemic stroke.Feb 05, 2017

Pubmed Data : J Biophotonics. 2017 Feb 6. Epub 2017 Feb 6. PMID: 28164443
Article Published Date : Feb 05, 2017
Study Type : Animal Study
Additional Links
Diseases : Stroke: Ischemic
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-18 down-regulation, Interleukin-1 beta downregulation, NF-kappaB Inhibitor
[+]

LED therapy provides an analgesic effect and modifies the expression of COX-2, PGE2, and proinflammatory cytokines in incised skin.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pain Res Manag. 2017 ;2017:4792489. Epub 2017 Apr 2. PMID: 28469528
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Diseases : Wound Healing
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions : Analgesics, Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Postaglandin PGE2 downregulation
[+]

LED therapy was able to increase the functional capacity evaluated by distance covered, time, and speed of exercise in rats with HF.Apr 07, 2016

Pubmed Data : Lasers Med Sci. 2016 Apr 8. Epub 2016 Apr 8. PMID: 27059227
Article Published Date : Apr 07, 2016
Study Type : Animal Study
Additional Links
Diseases : Fatigue, Heart Failure
Therapeutic Actions : Exercise, Light-Emitting Diodes (LEDs) Therapy
[+]

LED treatment ameliorates allergic lung inflammation in experimental model of asthma.Apr 17, 2017

Pubmed Data : J Biophotonics. 2017 Apr 18. Epub 2017 Apr 18. PMID: 28417574
Article Published Date : Apr 17, 2017
Study Type : Animal Study
Additional Links
Diseases : Asthma
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions : Anti-Inflammatory Agents, Interferon-gamma (IFN-gamma) inducer, Interleukin-10 upregulation
[+]

LED treatment reduced the release of IL-6 and TNF-α and increased the release of IL-10, improving the inflammatory response in OVX rats.Dec 31, 2015

Pubmed Data : Lasers Med Sci. 2016 Jan ;31(1):33-40. Epub 2015 Oct 27. PMID: 26507001
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Diseases : Tendon Injury
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Light-emitting diode therapy increases collagen deposition during the repair process of skeletal muscle.Feb 11, 2016

Pubmed Data : Lasers Med Sci. 2016 Feb 12. Epub 2016 Feb 12. PMID: 26873500
Article Published Date : Feb 11, 2016
Study Type : Animal Study
Additional Links
Diseases : Inflammation, Wounds and Injuries
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions : Anti-Inflammatory Agents, Matrix metalloproteinase-2 (MMP-2) inhibitor
[+]

Light-emitting diode therapy reduces persistent inflammatory pain.Mar 17, 2016

Pubmed Data : Neuroscience. 2016 Mar 18 ;324:485-495. Epub 2016 Mar 18. PMID: 27001179
Article Published Date : Mar 17, 2016
Study Type : Animal Study
Additional Links
Diseases : Inflammation, Pain
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions : Antioxidants, Catalase Up-Regulation, Interleukin-10 upregulation, Superoxide Dismutase Up-regulation
[+]

Low level laser therapy reduces the development of lung inflammation induced by formaldehyde exposure.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2015 ;10(11):e0142816. Epub 2015 Nov 16. PMID: 26569396
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Diseases : Formaldehyde Toxicity, Lung Inflammation
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions : Interleukin-10 upregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Formaldehyde
[+]

Low-level light emitting diode therapy promotes long-term functional recovery after experimental stroke in mice.May 01, 2017

Pubmed Data : J Biophotonics. 2017 May 2. Epub 2017 May 2. PMID: 28464523
Article Published Date : May 01, 2017
Study Type : Animal Study
Additional Links
Diseases : Stroke: Attenuation/Recovery
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
[+]

Non-irradiated control animals display inflammatory areas almost five times greater than the treated group.Sep 15, 2016

Pubmed Data : J Biophotonics. 2016 Sep 16. Epub 2016 Sep 16. PMID: 27635634
Article Published Date : Sep 15, 2016
Study Type : Animal Study
Additional Links
Diseases : Hyperglycemia, Inflammation, Obesity
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy, Photodynamic therapy
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Organic light emitting diode treatment improves diabetic cutaneous wound healing in rats.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Wound Repair Regen. 2015 Jan-Feb;23(1):104-14. Epub 2015 Mar 31. PMID: 25684653
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Diseases : Diabetic Complications, Wound Healing
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
[+]

Preventive laser and LED photo-biomodulation treatments were effective in diminishing the oral mucositis lesions.Mar 31, 2014

Pubmed Data : Clin Oral Investig. 2014 Apr ;18(3):1005-13. Epub 2013 Aug 15. PMID: 23949015
Article Published Date : Mar 31, 2014
Study Type : Animal Study
Additional Links
Diseases : Chemotherapy and Radiation Toxicity, Chemotherapy-Induced Toxicity: 5-fluorouracil , Oral Mucositis
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy, Photobiomodulation
Pharmacological Actions : Chemoprotective Agents
[+]

Red laser, infrared, photodynamic therapy and green LED light favored the healing process of third-degree burns in rats.Dec 31, 2014

Pubmed Data : Lasers Med Sci. 2015 Jan ;30(1):421-8. Epub 2014 Nov 13. PMID: 25391372
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Diseases : Burns, Burns: Severe, Wound Healing
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy, Photodynamic therapy
[+]

Red light modulates ultraviolet-induced gene expression in the epidermis of hairless mice.Sep 30, 2015

Pubmed Data : Photomed Laser Surg. 2015 Oct ;33(10):498-503. Epub 2015 Sep 23. PMID: 26398729
Article Published Date : Sep 30, 2015
Study Type : Animal Study
Additional Links
Diseases : Ultraviolet Radiation Induced Damage
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions : Cyclooxygenase 2 Inhibitors
Additional Keywords : Gene Expression Regulation
[+]

Short-range ultraviolet irradiation with LED device effectively increases serum levels of 25(OH)D.Oct 31, 2016

Pubmed Data : J Photochem Photobiol B. 2016 Nov ;164:256-263. Epub 2016 Sep 29. PMID: 27710873
Article Published Date : Oct 31, 2016
Study Type : Animal Study
Additional Links
Substances : Vitamin D
Diseases : Vitamin D Deficiency
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy, Light Therapy
[+]

Six bi-daily training sessions light-emitting diode regimens more than doubled muscle performance and increased ATP more than tenfold.Aug 31, 2015

Pubmed Data : J Biophotonics. 2015 Sep ;8(9):740-54. Epub 2014 Nov 6. PMID: 25378263
Article Published Date : Aug 31, 2015
Study Type : Animal Study
Additional Links
Diseases : Athletic Performance
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
[+]

These findings provide strong support for the promising therapeutic effect of photobiomodulation on neuronal repair following ischemic stroke.Oct 18, 2017

Pubmed Data : Exp Neurol. 2017 Oct 19. Epub 2017 Oct 19. PMID: 29056360
Article Published Date : Oct 18, 2017
Study Type : Animal Study
Additional Links
Diseases : Stroke: Ischemic
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy, Light Therapy, Photobiomodulation
Pharmacological Actions : Anti-Inflammatory Agents, Neurogenesis
[+]

Using curcumin as a photosensitizer and LED as the light source was effective in the treatment of induced periodontitis in rats.Jul 02, 2017

Pubmed Data : Lasers Med Sci. 2017 Jul 3. Epub 2017 Jul 3. PMID: 28674790
Article Published Date : Jul 02, 2017
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Periodontitis
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions : Photosensitizing Agents
[+]

280 nm UV LED irradiation inhibits proliferation and induces apoptosis and necrosis in cultured HL-60 human leukemia cells.Feb 29, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2016 Mar ;13(3):2506-10. Epub 2016 Jan 27. PMID: 26820261
Article Published Date : Feb 29, 2016
Study Type : In Vitro Study
Additional Links
Diseases : Leukemia: Acute promyelocytic leukemia
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions : Antiproliferative , Apoptotic, Bcl-2 protein down-regulation, Cell cycle arrest
Additional Keywords : Dose Response
[+]

Adjunctive 830 nm light-emitting diode therapy can improve the results following aesthetic procedures.Dec 29, 2015

Pubmed Data : Laser Ther. 2015 Dec 30 ;24(4):277-89. PMID: 26877592
Article Published Date : Dec 29, 2015
Study Type : Review
Additional Links
Diseases : Wound Healing
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
[+]

Blue light dosage affects carotenoids and tocopherols in microgreens.Jul 31, 2017

Pubmed Data : Food Chem. 2017 Aug 1 ;228:50-56. Epub 2017 Feb 1. PMID: 28317756
Article Published Date : Jul 31, 2017
Study Type : Plant Study
Additional Links
Substances : Carotenoids, Vitamin E
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Additional Keywords : Microgreens
[+]

Blue light emitting diode induces apoptosis in lymphoid cells by stimulating autophagy.Dec 31, 2015

Pubmed Data : Int J Biochem Cell Biol. 2016 Jan ;70:13-22. Epub 2015 Nov 10. PMID: 26555754
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Diseases : Lymphoma: B-Cell
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions : Apoptotic, Autophagy Up-regulation
[+]

Blue light triggers the cytotoxicity of riboflavins on HeLa cells in vitro.Jun 12, 2017

Pubmed Data : J Photochem Photobiol B. 2017 Jun 13 ;173:325-332. Epub 2017 Jun 13. PMID: 28633062
Article Published Date : Jun 12, 2017
Study Type : In Vitro Study
Additional Links
Substances : Riboflavin
Diseases : Cervical Cancer
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions : Apoptotic, Photosensitizing Agents
[+]

Chemoresistance to 5-FU was inhibited by 635 nm LED irradiation in CD133+ KB cell line.Sep 26, 2017

Pubmed Data : Lasers Med Sci. 2017 Sep 27. Epub 2017 Sep 27. PMID: 28956217
Article Published Date : Sep 26, 2017
Study Type : In Vitro Study
Additional Links
Diseases : Cancers: Drug Resistant, Oral Cancer
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions : Chemotherapeutic
Additional Keywords : Chemothapeutic Synergy: 5-flourouracil
[+]

Combined blue light emitting diode-high frequency focused ultrasound treatment could have therapeutic benefits to alleviate cancer cell proliferation.Sep 27, 2017

Pubmed Data : Comput Assist Surg (Abingdon). 2017 Sep 28:1-7. Epub 2017 Sep 28. PMID: 28956464
Article Published Date : Sep 27, 2017
Study Type : In Vitro Study
Additional Links
Diseases : Cervical Cancer
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy, Ultrasound therapy
Pharmacological Actions : Antiproliferative
[+]

Effect of low-level light therapy before radiotherapy in oral squamous cell carcinoma.Aug 23, 2022

Pubmed Data : Lasers Med Sci. 2022 Aug 24. Epub 2022 Aug 24. PMID: 36001245
Article Published Date : Aug 23, 2022
Study Type : In Vitro Study
Additional Links
Diseases : Oral Cancer
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions : Radiosensitizer
[+]

Hypocrellin B and light-emitting diode has potential as a therapeutic strategy for keloid.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Biol Sci. 2017 ;13(3):319-326. Epub 2017 Feb 25. PMID: 28367096
Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Diseases : Keloid
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions : Apoptotic
[+]

Increase in yield of lycopene and lutein content in tomatoes grown under continuous PAR spectrum LED lighting.Dec 31, 2020

Pubmed Data : Front Plant Sci. 2021 ;12:611236. Epub 2021 Feb 26. PMID: 33719284
Article Published Date : Dec 31, 2020
Study Type : Plant Study
Additional Links
Substances : Lutein, Lycopene, Tomato
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
[+]

LED Blue Light-induced changes in phenolics and ethylene in citrus fruit: Implication in elicited resistance against Penicillium digitatum infection.Feb 28, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Chem. 2017 Mar 1 ;218:575-583. Epub 2016 Sep 16. PMID: 27719952
Article Published Date : Feb 28, 2017
Study Type : Plant Study
Additional Links
Substances : Fruit: All
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions : Anti-fungal effects
[+]

LED irradiation at 465 nm inhibited the proliferation of HT29 and HCT116 cells as well as promoted apoptosis in HT29 cells.Aug 31, 2014

Pubmed Data : Anticancer Res. 2014 Sep ;34(9):4709-16. PMID: 25202048
Article Published Date : Aug 31, 2014
Study Type : In Vitro Study
Additional Links
Diseases : Colon Cancer
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

LED is a useful light source for deactivating the cancer cells because it can excite the sensitizers.Oct 20, 2017

Pubmed Data : Bioorg Med Chem. 2017 Oct 21. Epub 2017 Oct 21. PMID: 29108834
Article Published Date : Oct 20, 2017
Study Type : In Vitro Study
Additional Links
Diseases : Cholangiocarcinoma
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions : Chemosensitizer, Chemotherapeutic
[+]

LED therapy could be a potential non-invasive approach for treatment of retinal damage.Apr 30, 2017

Pubmed Data : Biomed Pharmacother. 2017 May ;89:1320-1330. Epub 2017 Mar 18. PMID: 28320099
Article Published Date : Apr 30, 2017
Study Type : In Vitro Study
Additional Links
Diseases : Eye Damage, Retinal Diseases
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions : Anti-Apoptotic, Nitric Oxide Inhibitor
[+]

Light emitting diode illumination causes photodynamic inactivation of Salmonella on fresh-cut papaya without deterioration.Mar 31, 2017

Pubmed Data : Food Microbiol. 2017 Apr ;62:124-132. Epub 2016 Oct 3. PMID: 27889138
Article Published Date : Mar 31, 2017
Study Type : Plant Study
Additional Links
Substances : Papaya
Diseases : Foodborne Pathogens: Prevention/Food Preservation
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
[+]

Light-emitting diode phototherapy: pain relief and underlying mechanisms.Jun 30, 2022

Pubmed Data : Lasers Med Sci. 2022 Jul ;37(5):2343-2352. Epub 2022 Apr 11. PMID: 35404002
Article Published Date : Jun 30, 2022
Study Type : Review
Additional Links
Diseases : Inflammation
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions : Analgesics
[+]

Light-emitting diodes may have therapeutic value for skin as an anti-aging modality. Jun 01, 2008

Pubmed Data : J Med Food. 2008 Jun;11(2):215-23. PMID: 17173579
Article Published Date : Jun 01, 2008
Study Type : Review
Additional Links
Diseases : Aging Skin
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
[+]

Low-level light therapy has significant potential to become a cost effective modality for treatment of diabetic foot ulcer.Jan 06, 2016

Pubmed Data : Wound Repair Regen. 2016 Jan 7. Epub 2016 Jan 7. PMID: 26748691
Article Published Date : Jan 06, 2016
Study Type : Review
Additional Links
Diseases : Diabetic Ulcer
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
[+]

Low-level light therapy is an effective biostimulator of adipose-derived stem cells in vascular regeneration.Jan 31, 2015

Pubmed Data : Lasers Med Sci. 2015 Feb ;30(2):533-41. Epub 2015 Jan 8. PMID: 25567209
Article Published Date : Jan 31, 2015
Study Type : In Vitro Study
Additional Links
Diseases : Ischemia, Wound Healing
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions : Regenerative
[+]

Photobotanical combinations may usher in new therapeutics or phototherapy adjuvants for the treatment of dermatologic diseases.Dec 31, 2016

Pubmed Data : Dermatol Surg. 2017 Jan ;43(1):81-86. PMID: 28027199
Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol
Diseases : Fibrosis, Skin Diseases
Therapeutic Actions : Integrative Medicine, Light-Emitting Diodes (LEDs) Therapy
[+]

Photodynamic inactivation of methicillin-resistant Staphylococcus aureus and Escherichia coli: A metalloporphyrin comparison.Nov 30, 2016

Pubmed Data : J Photochem Photobiol B. 2016 Dec ;165:51-57. Epub 2016 Oct 15. PMID: 27768953
Article Published Date : Nov 30, 2016
Study Type : In Vitro Study
Additional Links
Diseases : Escherichia coli Infections, Staphylococcus aureus: Methicillin-resistant (MRSA)
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions : Anti-Bacterial Agents
[+]

Pulsed light-emitting diodes could be used to promote higher phytochemical level in microgreens.Jun 14, 2017

Pubmed Data : J Agric Food Chem. 2017 Jun 15. Epub 2017 Jun 15. PMID: 28618783
Article Published Date : Jun 14, 2017
Study Type : Plant Study
Additional Links
Substances : Anthocyanins, Mustard Greens, Red Cabbage
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Additional Keywords : Microgreens
[+]

Red light-emitting diode light illumination could be a therapeutic option and positively affect wound healing processes.Jan 31, 2015

Pubmed Data : Dermatol Surg. 2015 Feb ;41(2):261-8. PMID: 25654197
Article Published Date : Jan 31, 2015
Study Type : In Vitro Study
Additional Links
Diseases : Wound Healing
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy, Light Therapy
[+]

Synergistic antimicrobial and antibiofilm activities were demonstrated when AgNPs were used in combination with blue light against P. aeruginosa.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Nanomedicine. 2016 ;11:1749-58. Epub 2016 Apr 27. PMID: 27175075
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Silver (nanoparticles)
Diseases : Pseudomonas aeruginosa
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions : Antimicrobial
[+]

The combination of curcumin with LED blue light united red light irradiation can attain a higher efficiency of regulating proliferation and apoptosis in skin keratinocytes.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2015;10(9):e0138754. Epub 2015 Sep 18. PMID: 26382065
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Inflammation, Psoriasis
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions : Anti-Inflammatory Agents, Antiproliferative
[+]

The triple combination of silver nanoparticles, blue light, and antibiotics is a promising therapy for infections caused by MRSA.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ann Clin Microbiol Antimicrob. 2016 ;15(1):48. Epub 2016 Aug 17. PMID: 27530257
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Silver (nanoparticles)
Diseases : Staphylococcus aureus: Methicillin-resistant (MRSA)
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions : Anti-Bacterial Agents
[+]

These results suggest that a synergistic effect between luteolin and LED could be a new effective therapy in relieving neuroinflammation.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Transl Res. 2018 ;10(1):283-291. Epub 2018 Jan 15. PMID: 29423013
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Luteolin
Diseases : Brain Inflammation
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

This concludes that both 405-nm laser and 405-nm LED’s on MRSA had similar antimicrobial effects.Sep 10, 2015

Pubmed Data : Lasers Med Sci. 2015 Sep 11. Epub 2015 Sep 11. PMID: 26362142
Article Published Date : Sep 10, 2015
Study Type : In Vitro Study
Additional Links
Diseases : Staphylococcus aureus: Methicillin-resistant (MRSA)
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy, Photobiomodulation
Pharmacological Actions : Antimicrobial
[+]

This paper also provides the basic mechanisms behind the effective LED therapies in treating cutaneous and neurological diseases.Sep 24, 2017

Pubmed Data : Ann Biomed Eng. 2017 Sep 25. Epub 2017 Sep 25. PMID: 28948402
Article Published Date : Sep 24, 2017
Study Type : Review
Additional Links
Diseases : Neurologic Disorders, Skin Diseases
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
[+]

Visible blue light and curcumin could be considered as a potential treatment for gram-negative periodontal pathogens.Mar 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Laser Ther. 2015 Mar 31 ;24(2):103-11. PMID: 26246690
Article Published Date : Mar 30, 2015
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Periodontal Diseases
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions : Anti-Bacterial Agents, Photosensitizing Agents

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