Ozone Therapy

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10 Diseases Researched for Ozone Therapy
NameACCKFocus
Herniated Disk220Locked
Ear Infection211Locked
Low Back Pain 110Locked
Multiple Myeloma110Locked
Neck Pain110Locked
Osteonecrosis110Locked
Otitis media110Locked
Ear Diseases11Locked
Inner Ear Disease11Locked
Periodontal Diseases11Locked

View the Evidence:
41 Abstracts with Ozone Therapy Research

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Effectiveness of ozone therapy compared to other therapies for low back pain.Sep 10, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Rev Bras Anestesiol. 2019 Sep 11. Epub 2019 Sep 11. PMID: 31521383
Article Published Date : Sep 10, 2019
Study Type : Meta Analysis, Review
Additional Links
Diseases : Low Back Pain
Therapeutic Actions : Ozone Therapy
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Intra-articular infiltrations of ozone can be used as an optional effective treatment for the management of pain related to knee osteoarthritis.Jan 27, 2019

Pubmed Data : PM R. 2019 Jan 28. Epub 2019 Jan 28. PMID: 30689297
Article Published Date : Jan 27, 2019
Study Type : Meta Analysis
Additional Links
Diseases : Osteoarthritis: Knee
Therapeutic Actions : Ozone Therapy
Pharmacological Actions : Analgesics
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"Ozone oxidative post-conditioning reduces oxidative protein damage in patients with disc hernia."Jan 01, 2012

Pubmed Data : Neurol Res. 2012 Jan ;34(1):59-67. PMID: 22196863
Article Published Date : Jan 01, 2012
Study Type : Human Study
Additional Links
Diseases : Herniated Disc, Neck Pain
Therapeutic Actions : Ozone Therapy
Pharmacological Actions : Antioxidants
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A systematic review of ozone therapy for the treatment of chronic wounds.Mar 12, 2018

Pubmed Data : Int Wound J. 2018 Mar 13. Epub 2018 Mar 13. PMID: 29536625
Article Published Date : Mar 12, 2018
Study Type : Human Study
Additional Links
Diseases : Wound Healing
Therapeutic Actions : Ozone Therapy
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Administration of ozone therapy along with the conventional medical treatment in patients hospitalised for COVID-19 could reduce mortality.Jul 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Clin Pract. 2021 Aug ;75(8):e14321. Epub 2021 May 24. PMID: 33971067
Article Published Date : Jul 31, 2021
Study Type : Human Study
Additional Links
Diseases : Coronavirus Infection
Therapeutic Actions : Ozone Therapy
Additional Keywords : Risk Reduction
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Efficacy of comprehensive ozone therapy in diabetic foot ulcer healing.Jan 31, 2019

Pubmed Data : Diabetes Metab Syndr. 2019 Jan - Feb;13(1):822-825. Epub 2018 Dec 1. PMID: 30641815
Article Published Date : Jan 31, 2019
Study Type : Human Study
Additional Links
Diseases : Diabetic Ulcer, Wound Healing
Therapeutic Actions : Ozone Therapy
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Innovative treatment of infantile atopic dermatitis with topical ozone application is safe and effective.Feb 27, 2018

Pubmed Data : Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2018 Feb 28 ;43(2):163-167. PMID: 29559600
Article Published Date : Feb 27, 2018
Study Type : Human Study
Additional Links
Diseases : Atopic Dermatitis: Infant & Childhood
Therapeutic Actions : Ozone Therapy
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Oxygen and ozone treatments are safe and efficacious in the treatment of herniated lumbar discsApr 01, 2010

Pubmed Data : J Vasc Interv Radiol. 2010 Apr;21(4):534-48. Epub 2010 Feb 25. PMID: 20188591
Article Published Date : Apr 01, 2010
Study Type : Human Study
Additional Links
Diseases : Herniated Disc, Low Back Pain
Therapeutic Actions : Hyperbaric Treatment, Oxygen Therapy , Ozone Therapy
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Ozone therapy accelerates cure time in patients treated for chronic suppurative otitis media.Jan 01, 1998

Pubmed Data : Vestn Otorinolaringol. 1998(6):11-2. PMID: 10081391
Article Published Date : Jan 01, 1998
Study Type : Human Study
Additional Links
Diseases : Ear Infection, Otitis media
Therapeutic Actions : Ozone Therapy
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Ozone therapy in 65 patients with fibromyalgia: an effective therapy.Jan 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Eur Rev Med Pharmacol Sci. 2019 Feb ;23(4):1786-1788. PMID: 30840304
Article Published Date : Jan 31, 2019
Study Type : Human Study
Additional Links
Diseases : Fibromyalgia
Therapeutic Actions : Ozone Therapy
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Ozone therapy is a potential therapeutic alternative for Multiple sclerosis patients.Sep 14, 2017

Pubmed Data : Eur J Pharmacol. 2017 Sep 15 ;811:148-154. Epub 2017 Jun 13. PMID: 28623000
Article Published Date : Sep 14, 2017
Study Type : Human Study
Additional Links
Diseases : Multiple Sclerosis
Therapeutic Actions : Ozone Therapy
Pharmacological Actions : Antioxidants, Interleukin-1 beta downregulation, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
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Ozone therapy may have a therapeutic role to play in bisphosphonate-associated osteonecrosis of the jaw in multiple myeloma patients. Sep 01, 2007

Pubmed Data : Haematologica. 2007 Sep;92(9):1289-90. PMID: 17768133
Article Published Date : Sep 01, 2007
Study Type : Human Study
Additional Links
Diseases : Multiple Myeloma, Osteonecrosis
Therapeutic Actions : Ozone Therapy
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Ozone therapy might be beneficial in terms of activating antioxidant system and merit further therapeutic potential to conventional heart failure treatment.Sep 30, 2017

Pubmed Data : Cardiovasc Toxicol. 2017 Oct ;17(4):426-433. PMID: 28097518
Article Published Date : Sep 30, 2017
Study Type : Human Study
Additional Links
Diseases : Heart Failure
Therapeutic Actions : Ozone Therapy
Pharmacological Actions : Antioxidants
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Ozone therapy resulted in the reduction of inflammation and normalization of local blood circulation in the periodontal tissues.Dec 31, 2016

Pubmed Data : Vopr Kurortol Fizioter Lech Fiz Kult. 2017 ;94(4):31-34. PMID: 29119958
Article Published Date : Dec 31, 2016
Study Type : Human Study
Additional Links
Diseases : Periodontal Diseases, Periodontitis
Therapeutic Actions : Ozone Therapy
Pharmacological Actions : Anti-Inflammatory Agents
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The study confirms the efficacy of ozone concerning pain relief, functional improvement, and quality of life in patients with knee osteoarthritis.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2017 ;12(7):e0179185. Epub 2017 Jul 24. PMID: 28738079
Article Published Date : Dec 31, 2016
Study Type : Human Study
Additional Links
Diseases : Osteoarthritis: Knee
Therapeutic Actions : Ozone Therapy
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Topical ozone therapy can effectively reduce S. aureus colony in skin lesions and alleviate the severity of atopic dermatitis.Feb 27, 2018

Pubmed Data : Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2018 Feb 28 ;43(2):157-162. PMID: 29559599
Article Published Date : Feb 27, 2018
Study Type : Human Study
Additional Links
Diseases : Staphylococcus aureus infection
Therapeutic Actions : Ozone Therapy
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Topical ozone therapy in patients with herpes zoster is helpful in relieving pain.Feb 27, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2018 Feb 28 ;43(2):168-172. PMID: 29559601
Article Published Date : Feb 27, 2018
Study Type : Human Study
Additional Links
Diseases : Herpes Zoster
Therapeutic Actions : Ozone Therapy
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Ozone gas plasma therapy may be helpful in prevention of gingival healing delay.Feb 28, 2018

Pubmed Data : Clin Oral Investig. 2018 Mar ;22(2):867-873. Epub 2017 Jul 11. PMID: 28699091
Article Published Date : Feb 28, 2018
Study Type : Human In Vitro
Additional Links
Diseases : Osteonecrosis, Wound Healing
Therapeutic Actions : Ozone Therapy
Pharmacological Actions : Genoprotective
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A case report of ozone therapy as a primary and sole treatment for acute bacterial infection.Jun 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Med Gas Res. 2018 Jul-Sep;8(3):121-124. Epub 2018 Sep 25. PMID: 30319768
Article Published Date : Jun 30, 2018
Study Type : Human: Case Report
Additional Links
Diseases : Bacterial Infections
Therapeutic Actions : Ozone Therapy
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A case report of treatment of osteoarthritis with low-level laser therapy, acupuncture, and herbal therapy.Mar 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Integr Med (Encinitas). 2018 Apr ;17(2):48-53. PMID: 30962785
Article Published Date : Mar 31, 2018
Study Type : Human: Case Report
Additional Links
Diseases : Osteoarthritis
Therapeutic Actions : Acupuncture, Ozone Therapy
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Biological assessment of ozone therapy on experimental oral candidiasis in immunosuppressed rats.Aug 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biochem Biophys Rep. 2018 Sep ;15:57-60. Epub 2018 Jul 11. PMID: 30069501
Article Published Date : Aug 31, 2018
Study Type : Animal Study
Additional Links
Diseases : Candidiasis
Therapeutic Actions : Ozone Therapy
Pharmacological Actions : Antifungal Agents
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Comparison of laser and ozone treatments on oral mucositis.Mar 31, 2017

Pubmed Data : Lasers Med Sci. 2017 Apr ;32(3):673-677. Epub 2017 Feb 11. PMID: 28190112
Article Published Date : Mar 31, 2017
Study Type : Animal Study
Additional Links
Diseases : Oral Mucositis, Wound Healing
Therapeutic Actions : Laser Treatment: Low-Level, Ozone Therapy
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Effect of subcutaneous topical ozone therapy on second-degree burn wounds.Jun 15, 2021

Pubmed Data : J Burn Care Res. 2021 Jun 16. Epub 2021 Jun 16. PMID: 34136919
Article Published Date : Jun 15, 2021
Study Type : Animal Study
Additional Links
Diseases : Burns, Wound Healing
Therapeutic Actions : Ozone Therapy
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Efficacy of ozone and selenium therapy for alcoholic liver injury.Apr 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : In Vivo. 2019 May-Jun;33(3):763-769. PMID: 31028195
Article Published Date : Apr 30, 2019
Study Type : Animal Study
Additional Links
Substances : Selenium
Diseases : Alcoholic Liver Disease
Therapeutic Actions : Ozone Therapy
Pharmacological Actions : Antioxidants, Hepatoprotective
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Ozone prevents cochlear damage from ischemia-reperfusion injury.Jul 31, 2017

Pubmed Data : Artif Organs. 2017 Aug ;41(8):744-752. Epub 2017 Mar 5. PMID: 28261890
Article Published Date : Jul 31, 2017
Study Type : Animal Study
Additional Links
Diseases : Ischemia
Therapeutic Actions : Ozone Therapy
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Ozone protects rat heart against ischemia-reperfusion injury.Mar 31, 2017

Pubmed Data : Biomed Pharmacother. 2017 Apr ;88:1090-1097. Epub 2017 Feb 10. PMID: 28192883
Article Published Date : Mar 31, 2017
Study Type : Animal Study
Additional Links
Diseases : Myocardial Ischemia
Therapeutic Actions : Ozone Therapy
Pharmacological Actions : Antioxidants, Cardioprotective
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Ozone protects the rat lung from ischemia-reperfusion injury.Sep 14, 2018

Pubmed Data : Eur J Pharmacol. 2018 Sep 15 ;835:82-93. Epub 2018 Jul 31. PMID: 30075224
Article Published Date : Sep 14, 2018
Study Type : Animal Study
Additional Links
Diseases : Inflammation, Oxidative Stress
Therapeutic Actions : Ozone Therapy
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Nrf2 activation
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Ozone showed beneficial effects on acetaminophen hepatotoxicity at a statistically significant level.Nov 12, 2017

Pubmed Data : Pharmacol Rep. 2017 Nov 13 ;70(2):340-345. Epub 2017 Nov 13. PMID: 29477043
Article Published Date : Nov 12, 2017
Study Type : Animal Study
Additional Links
Diseases : Acetaminophen (Tylenol) Toxicity
Therapeutic Actions : Ozone Therapy
Pharmacological Actions : Hepatoprotective
Problem Substances : Acetaminophen, Paracetamol
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Ozone therapy ameliorates inflammation and endometrial injury in rats with pelvic inflammatory disease.Oct 31, 2018

Pubmed Data : Biomed Pharmacother. 2018 Nov ;107:1418-1425. Epub 2018 Sep 1. PMID: 30257358
Article Published Date : Oct 31, 2018
Study Type : Animal Study
Additional Links
Diseases : Inflammation, Pelvic Inflammatory Disease
Therapeutic Actions : Ozone Therapy
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
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Ozone therapy improved sciatic nerve injury recovery without causing an increase in fibrotic tissue.Aug 31, 2017

Pubmed Data : World Neurosurg. 2017 Sep ;105:702-708. Epub 2017 Jun 3. PMID: 28587982
Article Published Date : Aug 31, 2017
Study Type : Animal Study
Additional Links
Diseases : Sciatic Nerve Crush Injury
Therapeutic Actions : Ozone Therapy
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Ozone therapy reduces oxidative stress and testicular damage in an experimental model of testicular torsion.Oct 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int Braz J Urol. 2017 Nov-Dec;43(6):1160-1166. PMID: 28727368
Article Published Date : Oct 31, 2017
Study Type : Animal Study
Additional Links
Diseases : Oxidative Stress, Testicular Torsion
Therapeutic Actions : Ozone Therapy
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These biochemical and histopathological findings suggest that ellagic acid and ozone are effective against ovarian ischemia/reperfusion injury.Dec 31, 2015

Pubmed Data : J Obstet Gynaecol Res. 2016 Jan ;42(1):52-8. Epub 2015 Nov 10. PMID: 26555146
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Ellagic Acid
Diseases : Ischemia, Oxidative Stress
Therapeutic Actions : Ozone Therapy
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation, Superoxide Dismutase Up-regulation
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These preliminary results support the hypothesis that O3 therapy is effective against papillomavirus-induced lesions.Jul 31, 2018

Pubmed Data : Biomed Pharmacother. 2018 Aug ;104:275-279. Epub 2018 May 25. PMID: 29775895
Article Published Date : Jul 31, 2018
Study Type : Transgenic Animal Study
Additional Links
Diseases : Human Papillomavirus (HPV)
Therapeutic Actions : Ozone Therapy
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These results indicated that ozone therapy might reduce sterile renal inflammation and slow down chronic kidney disease progression.Jan 31, 2017

Pubmed Data : Int Immunopharmacol. 2017 Feb ;43:203-209. Epub 2016 Dec 27. PMID: 28038382
Article Published Date : Jan 31, 2017
Study Type : Animal Study
Additional Links
Diseases : Chronic Kidney Disease (CKD), Inflammation
Therapeutic Actions : Ozone Therapy
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Renoprotective
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A review of ozone therapy for diabetic foot ulcers.Jun 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Med Gas Res. 2018 Jul-Sep;8(3):111-115. Epub 2018 Sep 25. PMID: 30319766
Article Published Date : Jun 30, 2018
Study Type : Review
Additional Links
Diseases : Diabetic Complications, Diabetic Ulcer
Therapeutic Actions : Ozone Therapy
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Cannabidiol and oxygen-ozone combination induce cytotoxicity in human pancreatic ductal adenocarcinoma cell lines.Sep 26, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancers (Basel). 2020 Sep 27 ;12(10). Epub 2020 Sep 27. PMID: 32992648
Article Published Date : Sep 26, 2020
Study Type : In Vitro Study
Additional Links
Substances : Cannabidiol
Diseases : Pancreatic Cancer
Therapeutic Actions : Ozone Therapy
Pharmacological Actions : Chemotherapeutic
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Medical ozone inhibits the growth of periodontal pathogens. Aug 01, 2004

Pubmed Data : Am J Perinatol. 2004 Aug;21(6):333-9. PMID: 16353031
Article Published Date : Aug 01, 2004
Study Type : Commentary
Additional Links
Diseases : Periodontal Diseases
Therapeutic Actions : Ozone Therapy
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Ozone exerts cardioprotective and dermatoprotective effects during incubation with doxorubicin.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2019 ;2019:2169103. Epub 2019 Nov 18. PMID: 31827546
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Diseases : Chemotherapy-Induced Toxicity: Doxorubicin
Therapeutic Actions : Ozone Therapy
Pharmacological Actions : Cardioprotective, Chemoprotective Agents
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Ozone therapy may have therapeutic value in the treatment of patients with acute and chronic suppurative middle ear diseases.Jan 01, 2009

Pubmed Data : Vestn Otorinolaringol. 2009(3):34-5. PMID: 19692964
Article Published Date : Jan 01, 2009
Study Type : Commentary
Additional Links
Diseases : Ear Diseases, Ear Infection, Inner Ear Disease
Therapeutic Actions : Ozone Therapy
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Therapeutic relevance of ozone therapy in degenerative diseases.Mar 31, 2018

Pubmed Data : J Cell Physiol. 2018 Apr ;233(4):2705-2714. Epub 2017 Jul 11. PMID: 28594115
Article Published Date : Mar 31, 2018
Study Type : Review
Additional Links
Diseases : Spinal Pain
Therapeutic Actions : Ozone Therapy
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Nrf2 activation
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This review concludes that ozone therapy is a novel, safe, and inexpensive approach for reflex sympathetic dystrophy/complex regional pain syndrome, and an alternative to drugs.May 06, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Curr Pain Headache Rep. 2019 May 6 ;23(6):41. Epub 2019 May 6. PMID: 31062104
Article Published Date : May 06, 2019
Study Type : Review
Additional Links
Diseases : Complex Regional Pain Syndrome: Type I, Complex Regional Pain Syndrome: Type II, Reflex Sympathetic Dystrophy
Therapeutic Actions : Ozone Therapy

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Hyperbaric oxygen treatment is recognized by Medicare in the United States as a reimbursable treatment for 14 "approved" conditions. Indeed, it is one of the most natural and effective prescriptions offered by conventional medicine today.
Ozone Therapy is Powerful Medicine
Written by Valerie Burke
This little-known therapy is being used by 40,000 physicians and dentists in more than 50 countries for everything from herniated disks to endodontic infections to Lyme disease, with no virtually adverse effects

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