Acrylamide

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28 Diseases Researched for Acrylamide
NameACCKFocus
Acrylamide-induced toxicity58101Locked
Oxidative Stress1731Locked
Breast Cancer220Locked
Lipid Peroxidation314Locked
Kidney Damage: Chemically-Induced612Locked
Breast Cancer: Prevention211Locked
Chemically-Induced Liver Damage611Locked
C-Reactive Protein110Locked
Cholesterol: Oxidation110Locked
Endometrial Cancer110Locked
Ovarian Cancer110Locked
Testicular Injury: Chemical/Metal Induced510Locked
Neurodegenerative Diseases48Locked
Aluminum Toxicity 36Locked
Brain Inflammation 36Locked
DNA damage35Locked
Inflammation24Locked
Autism Spectrum Disorders12Locked
Cognitive Decline/Dysfunction12Locked
Depression12Locked
Diabetic Complications12Locked
Eye Damage12Locked
Infertility: Female12Locked
Infertility: Male12Locked
Prenatal Chemical Exposures12Locked
Atherosclerosis11Locked
Cancers: All11Locked
Cardiovascular Diseases11Locked
8 Adverse Pharmacological Actions Researched for Acrylamide
NameACCKFocus
Genotoxic314Locked
Inflammatory313Locked
Atherogenic110Locked
Carcinogenic110Locked
Cardiotoxic11Locked
Cycloogenase-2 enzyme upregulation11Locked
Mutagenic11Locked
iNOS upregulation11Locked

View the Evidence:
71 Abstracts with Acrylamide Research

[+]

Chronic ingestion of acrylamide-containing products (potato chips) induces a proinflammatory state, a risk factor for progression of atherosclerosis.Mar 01, 2009

Pubmed Data : Am J Clin Nutr. 2009 Mar ;89(3):773-7. Epub 2009 Jan 21. PMID: 19158207
Article Published Date : Mar 01, 2009
Study Type : Human Study
Additional Links
Diseases : C-Reactive Protein, Cholesterol: Oxidation, Lipid Peroxidation
Pharmacological Actions : Interleukin-6 Downregulation
Problem Substances : Acrylamide , Potato, Potato Chips
Adverse Pharmacological Actions : Atherogenic, Inflammatory
[+]

Hazardous air pollutants and breast cancer risk in California teachers: a cohort study.Jan 29, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Health. 2015 Jan 30 ;14(1):14. Epub 2015 Jan 30. PMID: 25636809
Article Published Date : Jan 29, 2015
Study Type : Human Study
Additional Links
Diseases : Breast Cancer
Problem Substances : Acrylamide , Benzene, Vinyl chloride
Adverse Pharmacological Actions : Carcinogenic
[+]

Pre-diagnostic exposure to acrylamide may be related to mortality among breast cancer patients and that this may especially concern the most endocrine related type of breast cancer.Jun 13, 2012

Pubmed Data : Toxicology. 2012 Jun 14 ;296(1-3):67-72. Epub 2012 Mar 20. PMID: 22465873
Article Published Date : Jun 13, 2012
Study Type : Human Study
Additional Links
Diseases : Breast Cancer, Breast Cancer: Prevention
Problem Substances : Acrylamide
Adverse Pharmacological Actions : Genotoxic
[+]

There is a positive associations with endometrial and ovarian cancers and acrylamide exposure. Sep 30, 2010

Pubmed Data : Cancer Epidemiol Biomarkers Prev. 2010 Oct ;19(10):2503-15. Epub 2010 Aug 6. PMID: 20693310
Article Published Date : Sep 30, 2010
Study Type : Human Study
Additional Links
Diseases : Endometrial Cancer, Ovarian Cancer
Pharmacological Actions : Carcinogens
Problem Substances : Acrylamide
[+]

Acrylamide aggravates cognitive deficits at night period via the gut-brain axis by reprogramming the brain circadian clock.Oct 28, 2018

Pubmed Data : Arch Toxicol. 2018 Oct 29. Epub 2018 Oct 29. PMID: 30374679
Article Published Date : Oct 28, 2018
Study Type : Animal Study
Additional Links
Diseases : Acrylamide-induced toxicity, Cognitive Decline/Dysfunction
Additional Keywords : Gut-brain Axis
Problem Substances : Acrylamide
[+]

Allicin alleviates mitochondrial dysfunction in acrylamide-induced rat kidney involving the regulation of SIRT1.Oct 24, 2023

Pubmed Data : J Agric Food Chem. 2023 Oct 25 ;71(42):15785-15795. Epub 2023 Oct 13. PMID: 37830900
Article Published Date : Oct 24, 2023
Study Type : Animal Study
Additional Links
Substances : Allicin
Diseases : Acrylamide-induced toxicity
Pharmacological Actions : Anti-Apoptotic, SIRT1 Activator
Problem Substances : Acrylamide
[+]

Allicin is highly effective in the treatment and prevention of acrylamide-induced intestinal injury.Oct 24, 2021

Pubmed Data : J Agric Food Chem. 2021 Oct 25. Epub 2021 Oct 25. PMID: 34694121
Article Published Date : Oct 24, 2021
Study Type : Animal Study
Additional Links
Substances : Allicin
Diseases : Acrylamide-induced toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents, Gastroprotective
Problem Substances : Acrylamide
[+]

Blueberry anthocyanins extract attenuates acrylamide-induced oxidative stress and neuroinflammation.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2022 ;2022:7340881. Epub 2022 May 23. PMID: 35651724
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Anthocyanins, Blueberry
Diseases : Brain Inflammation , Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Brain-derived neurotrophic factor modulator, Neuroprotective Agents
Problem Substances : Acrylamide
[+]

Boron could protect against acrylamide induced oxidative stress and inflammation. Jun 14, 2018

Pubmed Data : Food Chem Toxicol. 2018 Jun 15. Epub 2018 Jun 15. PMID: 29913234
Article Published Date : Jun 14, 2018
Study Type : Animal Study
Additional Links
Substances : Boron
Diseases : Acrylamide-induced toxicity, Brain Inflammation , Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective, Hypolipidemic
Problem Substances : Acrylamide
[+]

Carnosic acid attenuates acrylamide-induced retinal toxicity in zebrafish embryos.Jan 09, 2018

Pubmed Data : Exp Eye Res. 2018 10 ;175:103-114. Epub 2018 Jun 18. PMID: 29928899
Article Published Date : Jan 09, 2018
Study Type : Animal Study
Additional Links
Substances : Carnosic Acid
Diseases : Acrylamide-induced toxicity, Eye Damage, Oxidative Stress
Pharmacological Actions : Antioxidants, Neuroprotective Agents, Superoxide Dismutase Up-regulation
Problem Substances : Acrylamide
[+]

Carvacrol prevents acrylamide-induced oxidative and inflammatory liver damage and dysfunction.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2023 ;14:1161448. Epub 2023 Apr 5. PMID: 37089925
Article Published Date : Dec 31, 2022
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Acrylamide-induced toxicity, Chemically-Induced Liver Damage
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective, Interleukin-1 beta downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Acrylamide
[+]

Co-exposure to aluminum and acrylamide exhibited synergism and more pronounced toxic effects compared with their individual effects.Apr 08, 2015

Pubmed Data : Environ Toxicol. 2015 Apr 9. Epub 2015 Apr 9. PMID: 25858877
Article Published Date : Apr 08, 2015
Study Type : Animal Study
Additional Links
Diseases : Acrylamide-induced toxicity, Aluminum Toxicity , Kidney Damage: Chemically-Induced
Additional Keywords : Synergistic Toxicity
Problem Substances : Acrylamide , Aluminum
Adverse Pharmacological Actions : Genotoxic, Inflammatory
[+]

Concomitant administration of resveratrol and resistance training ameliorates acrylamide-induced spatial learning impairment.Dec 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Avicenna J Phytomed. 2024 ;14(2):177-188. PMID: 38966625
Article Published Date : Dec 31, 2023
Study Type : Animal Study
Additional Links
Diseases : Acrylamide-induced toxicity
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Acrylamide
[+]

Dark chocolate can be used as effective supplement to decrease the dietary acrylamide cerebellar neuronal risks.Oct 17, 2021

Pubmed Data : Mol Neurobiol. 2021 Oct 18. Epub 2021 Oct 18. PMID: 34661852
Article Published Date : Oct 17, 2021
Study Type : Animal Study
Additional Links
Substances : Chocolate
Diseases : Acrylamide-induced toxicity
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Acrylamide
[+]

Dietary lipoic acid alleviates autism-like behavior induced by acrylamide.Apr 01, 2024

Pubmed Data : Food Funct. 2024 Apr 2 ;15(7):3395-3410. Epub 2024 Apr 2. PMID: 38465655
Article Published Date : Apr 01, 2024
Study Type : Animal Study
Additional Links
Substances : Alpha-Lipoic Acid
Diseases : Autism Spectrum Disorders, Depression
Pharmacological Actions : Gastrointestinal Agents
Additional Keywords : Gut-brain Axis
Problem Substances : Acrylamide
[+]

Effect of carnosic acid on acrylamide induced neurotoxicity.Nov 18, 2020

Pubmed Data : Drug Chem Toxicol. 2020 Nov 19:1-8. Epub 2020 Nov 19. PMID: 33213219
Article Published Date : Nov 18, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Carnosic Acid
Diseases : Acrylamide-induced toxicity
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Malondialdehyde Down-regulation, Neuroprotective Agents
Problem Substances : Acrylamide
[+]

Effect of royal jelly on acrylamide-induced neurotoxicity in rats.Nov 01, 2023

Pubmed Data : J Chem Neuroanat. 2023 Nov 2 ;134:102358. Epub 2023 Nov 2. PMID: 37925036
Article Published Date : Nov 01, 2023
Study Type : Animal Study
Additional Links
Substances : Royal Jelly
Diseases : Acrylamide-induced toxicity
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Problem Substances : Acrylamide
[+]

Eruca sativa seed extract modulates oxidative stress and apoptosis and up-regulates the expression of Bcl-2 and Bax genes in acrylamide-induced testicular dysfunction.Sep 30, 2021

Pubmed Data : Environ Sci Pollut Res Int. 2021 Oct ;28(38):53249-53266. Epub 2021 May 23. PMID: 34024031
Article Published Date : Sep 30, 2021
Study Type : Animal Study
Additional Links
Substances : Arugula
Diseases : Acrylamide-induced toxicity, Oxidative Stress, Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Anti-Apoptotic, Antioxidants
Additional Keywords : Plant Extracts
Problem Substances : Acrylamide
[+]

Eugenol alleviates acrylamide-induced rat testicular toxicity.Jan 21, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2024 Jan 22 ;14(1):1910. Epub 2024 Jan 22. PMID: 38253778
Article Published Date : Jan 21, 2024
Study Type : Animal Study
Additional Links
Substances : Eugenol
Diseases : Acrylamide-induced toxicity, Testicular Injury: Chemical/Metal Induced
Problem Substances : Acrylamide
[+]

Evaluating the effect of alpha-mangostin on neural toxicity induced by acrylamide.Aug 31, 2023

Pubmed Data : Environ Sci Pollut Res Int. 2023 Sep ;30(42):95789-95800. Epub 2023 Aug 9. PMID: 37556057
Article Published Date : Aug 31, 2023
Study Type : Animal Study
Additional Links
Substances : Xanthones
Diseases : Acrylamide-induced toxicity, Neurodegenerative Diseases, Oxidative Stress
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents
Problem Substances : Acrylamide
[+]

Extra virgin olive oil can decrease the frequency of cardiac complications and genotoxicity induced by co-exposure to aluminum and acrylamide.Sep 01, 2015

Pubmed Data : Food Funct. 2015 Sep 2 ;6(9):3098-108. PMID: 26215160
Article Published Date : Sep 01, 2015
Study Type : Animal Study
Additional Links
Substances : Olive Oil
Diseases : Acrylamide-induced toxicity, Aluminum Toxicity
Pharmacological Actions : Antioxidants, Cardioprotective, Genoprotective
Problem Substances : Acrylamide , Aluminum
Adverse Pharmacological Actions : Genotoxic
[+]

Extra virgin olive oil may have a beneficial role in decreasing the liver damage induced by both aluminum and acrylamide.Mar 31, 2015

Pubmed Data : Food Funct. 2015 Apr ;6(4):1126-35. PMID: 25690328
Article Published Date : Mar 31, 2015
Study Type : Animal Study
Additional Links
Substances : Olive Oil
Diseases : Acrylamide-induced toxicity, Aluminum Toxicity , Chemically-Induced Liver Damage
Pharmacological Actions : Hepatoprotective
Problem Substances : Acrylamide , Aluminum
[+]

Extra virgin olive oil might provide a basis for developing a new dietary supplementation strategy in order to prevent lung tissue damage.Jul 03, 2016

Pubmed Data : Environ Sci Pollut Res Int. 2016 Jul 4. Epub 2016 Jul 4. PMID: 27378219
Article Published Date : Jul 03, 2016
Study Type : Animal Study
Additional Links
Substances : Olive Oil
Diseases : DNA damage, Oxidative Stress
Pharmacological Actions : Cytoprotective
Problem Substances : Acrylamide , Aluminum Chloride
[+]

L. sativum seed oil attenuated ovarian damage and could potentially be a new supplemental agent against female infertility. Jun 30, 2024

Pubmed Data : Chem Biodivers. 2024 Jul ;21(7):e202400062. Epub 2024 Jun 22. PMID: 38743868
Article Published Date : Jun 30, 2024
Study Type : Animal Study
Additional Links
Substances : Garden Cress (Lepidium sativum)
Diseases : Acrylamide-induced toxicity, DNA damage, Infertility: Female, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Fertility Agents: Female
Problem Substances : Acrylamide
[+]

Lactobacillus reuteri JCM 1112 ameliorates chronic acrylamide-induced glucose metabolism disorder.Jun 16, 2024

Pubmed Data : Food Funct. 2024 Jun 17 ;15(12):6450-6458. Epub 2024 Jun 17. PMID: 38804210
Article Published Date : Jun 16, 2024
Study Type : Animal Study
Additional Links
Substances : Lactobacillus reuteri
Diseases : Acrylamide-induced toxicity, Oxidative Stress
Pharmacological Actions : Antioxidants
Problem Substances : Acrylamide
[+]

Melatonin alleviated acrylamide induced lipid peroxidation and depressed antioxidant capacity.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2015;2015:703709. Epub 2015 Jun 21. PMID: 26185593
Article Published Date : Dec 31, 2014
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Melatonin
Diseases : Acrylamide-induced toxicity, Oxidative Stress
Pharmacological Actions : Antioxidants, Chemopreventive
Additional Keywords : Risk Reduction
Problem Substances : Acrylamide
[+]

Metabolomics analysis of the effects of quercetin on hepatotoxicity induced by acrylamide exposure.Jul 07, 2021

Pubmed Data : Free Radic Res. 2021 Jul 8:1-36. Epub 2021 Jul 8. PMID: 34238086
Article Published Date : Jul 07, 2021
Study Type : Animal Study
Additional Links
Substances : Quercetin
Diseases : Acrylamide-induced toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective
Problem Substances : Acrylamide
[+]

Neuroprotective effects of ellagic acid against acrylamide-induced neurotoxicity.Feb 07, 2019

Pubmed Data : Neurol Res. 2019 Feb 8:1-10. Epub 2019 Feb 8. PMID: 30735102
Article Published Date : Feb 07, 2019
Study Type : Animal Study
Additional Links
Substances : Ellagic Acid
Diseases : Acrylamide-induced toxicity
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Acrylamide
[+]

Oleuropein mitigates acrylamide-induced nephrotoxicity. Sep 30, 2023

Pubmed Data : Eurasian J Med. 2023 Oct ;55(3):228-233. PMID: 37909193
Article Published Date : Sep 30, 2023
Study Type : Animal Study
Additional Links
Substances : Oleuropein
Diseases : Acrylamide-induced toxicity, Kidney Damage: Chemically-Induced
Pharmacological Actions : Renoprotective
Problem Substances : Acrylamide
[+]

P. crispum showed protective effects against acrylamide-induced reproductive toxicity.Apr 15, 2024

Pubmed Data : Reprod Toxicol. 2024 Apr 16 ;126:108586. Epub 2024 Apr 16. PMID: 38614435
Article Published Date : Apr 15, 2024
Study Type : Animal Study
Additional Links
Substances : Parsley
Diseases : Acrylamide-induced toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Acrylamide
[+]

Pomegranate peel has anti-inflammatory, antiapoptotic, free-radical-scavenging, and powerful antioxidant activity that protects against acrylamide toxicity.Jan 30, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Life (Basel). 2022 Jan 31 ;12(2). Epub 2022 Jan 31. PMID: 35207511
Article Published Date : Jan 30, 2022
Study Type : Animal Study
Additional Links
Substances : Ellagic Acid, Pomegranate Peel
Diseases : Acrylamide-induced toxicity
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Hepatoprotective, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Nrf2 activation
Problem Substances : Acrylamide
[+]

Potential protective effects of Spirulina platensis on liver, kidney, and brain acrylamide toxicity.Jan 24, 2021

Pubmed Data : Environ Sci Pollut Res Int. 2021 Jan 25. Epub 2021 Jan 25. PMID: 33492591
Article Published Date : Jan 24, 2021
Study Type : Animal Study
Additional Links
Substances : Spirulina
Diseases : Acrylamide-induced toxicity
Pharmacological Actions : Hepatoprotective, Neuroprotective Agents, Renoprotective
Problem Substances : Acrylamide
[+]

Protective effect of acorus calamus against acrylamide induced neurotoxicity.Apr 30, 2002

Pubmed Data : Phytother Res. 2002 May ;16(3):256-60. PMID: 12164272
Article Published Date : Apr 30, 2002
Study Type : Animal Study
Additional Links
Substances : Acorus calamus
Diseases : Acrylamide-induced toxicity, Neurodegenerative Diseases
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Phytotherapy, Plant Extracts
Problem Substances : Acrylamide
[+]

Protective effect of Lycium ruthenicum polyphenols on oxidative stress against acrylamide induced liver injury.Jun 24, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2022 Jun 25 ;27(13). Epub 2022 Jun 25. PMID: 35807346
Article Published Date : Jun 24, 2022
Study Type : Animal Study
Additional Links
Substances : Goji, Polyphenols
Diseases : Acrylamide-induced toxicity, Oxidative Stress
Pharmacological Actions : Antioxidants, Hepatoprotective
Problem Substances : Acrylamide
[+]

Protective effect of taxifolin against prooxidant and proinflammatory kidney damage associated with acrylamide.Jun 30, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2021 Jul ;139:111660. Epub 2021 May 11. PMID: 34243628
Article Published Date : Jun 30, 2021
Study Type : Animal Study
Additional Links
Substances : Flavonoids
Diseases : Acrylamide-induced toxicity, Inflammation, Kidney Damage: Chemically-Induced, Oxidative Stress
Pharmacological Actions : anti-inflammatory, Antioxidants, Interleukin-1 beta downregulation, Malondialdehyde Down-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Acrylamide
[+]

Protective effects of crocin on acrylamide-induced testis damage.Jul 25, 2021

Pubmed Data : Andrologia. 2021 Jul 26:e14176. Epub 2021 Jul 26. PMID: 34309867
Article Published Date : Jul 25, 2021
Study Type : Animal Study
Additional Links
Substances : Crocin
Diseases : Acrylamide-induced toxicity, Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Antioxidants
Problem Substances : Acrylamide
[+]

Protective effects of hesperidin and diosmin against acrylamide-induced liver, kidney, and brain oxidative damage.Nov 30, 2019

Pubmed Data : Environ Sci Pollut Res Int. 2019 Dec ;26(34):35151-35162. Epub 2019 Nov 4. PMID: 31686333
Article Published Date : Nov 30, 2019
Study Type : Animal Study
Additional Links
Substances : Diosmin , Hesperidin
Diseases : Acrylamide-induced toxicity, Chemically-Induced Liver Damage, Kidney Damage: Chemically-Induced
Pharmacological Actions : Antioxidants, Hepatoprotective, Neuroprotective Agents, Renoprotective
Problem Substances : Acrylamide
[+]

Protective effects of vitamin E against acrylamide-induced hepatotoxicity and nephrotoxicity.Jan 17, 2024

Pubmed Data : Toxicology. 2024 Jan 18 ;502:153729. Epub 2024 Jan 18. PMID: 38242491
Article Published Date : Jan 17, 2024
Study Type : Animal Study
Additional Links
Substances : Vitamin E
Diseases : Acrylamide-induced toxicity, Chemically-Induced Liver Damage, Kidney Damage: Chemically-Induced, Prenatal Chemical Exposures
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
Problem Substances : Acrylamide
[+]

Protective efficacy of rutin against acrylamide-induced oxidative stress, biochemical alterations and histopathological lesions in rats.Jan 31, 2022

Pubmed Data : Toxicol Res (Camb). 2022 Feb ;11(1):215-225. Epub 2022 Jan 26. PMID: 35237426
Article Published Date : Jan 31, 2022
Study Type : Animal Study
Additional Links
Substances : Rutin
Diseases : Acrylamide-induced toxicity
Pharmacological Actions : Antioxidants, Hepatoprotective, Renoprotective
Problem Substances : Acrylamide
[+]

Protective role of vitamin E against acrylamide-induced testicular toxicity from pregnancy to adulthood.Jul 28, 2023

Pubmed Data : Naunyn Schmiedebergs Arch Pharmacol. 2023 Jul 29. Epub 2023 Jul 29. PMID: 37515736
Article Published Date : Jul 28, 2023
Study Type : Animal Study
Additional Links
Substances : Vitamin E
Diseases : Acrylamide-induced toxicity, Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Aromatase Inhibitors
Problem Substances : Acrylamide
[+]

Punicalagin can protect against acrylamide-induced toxicity through antioxidant and anti-apoptotic properties.Jun 26, 2020

Pubmed Data : Phytother Res. 2020 Jun 27. Epub 2020 Jun 27. PMID: 32592417
Article Published Date : Jun 26, 2020
Study Type : Animal Study
Additional Links
Substances : Punicalagin
Diseases : Acrylamide-induced toxicity
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Hepatoprotective, Neuroprotective Agents
Problem Substances : Acrylamide
[+]

Quercetin is able to significantly alleviate the toxicity induced by acrylamide in rats.Jan 31, 2017

Pubmed Data : Biomed Pharmacother. 2017 Feb ;86:705-714. Epub 2016 Dec 28. PMID: 28039850
Article Published Date : Jan 31, 2017
Study Type : Animal Study
Additional Links
Substances : Quercetin
Diseases : Acrylamide-induced toxicity, Lipid Peroxidation, Neurodegenerative Diseases, Oxidative Stress
Pharmacological Actions : Antioxidants
Problem Substances : Acrylamide
[+]

Rutin has a protective effect against brain injury induced by acrylamide or gamma radiation.Sep 13, 2017

Pubmed Data : Arch Physiol Biochem. 2017 Sep 14:1-9. Epub 2017 Sep 14. PMID: 28906145
Article Published Date : Sep 13, 2017
Study Type : Animal Study
Additional Links
Substances : Rutin
Diseases : Acrylamide-induced toxicity
Pharmacological Actions : Neuroprotective Agents, Radioprotective
Problem Substances : Acrylamide
[+]

The protective effects of 18β-glycyrrhetinic acid against acrylamide-induced cellular damage in diabetic rats.Jun 10, 2021

Pubmed Data : Environ Sci Pollut Res Int. 2021 Jun 11. Epub 2021 Jun 11. PMID: 34117542
Article Published Date : Jun 10, 2021
Study Type : Animal Study
Additional Links
Substances : 18β-Glycyrrhetinic Acid
Diseases : Acrylamide-induced toxicity, Chemically-Induced Liver Damage, Diabetic Complications, Kidney Damage: Chemically-Induced
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Renoprotective
Problem Substances : Acrylamide
[+]

Therapeutic effects of thymoquinone or capsaicin on acrylamide-induced reproductive toxicity.Jul 06, 2021

Pubmed Data : Drug Chem Toxicol. 2021 Jul 7:1-13. Epub 2021 Jul 7. PMID: 34233550
Article Published Date : Jul 06, 2021
Study Type : Animal Study
Additional Links
Substances : Capsaicin, Thymoquinone
Diseases : Infertility: Male, Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, NF-kappaB Inhibitor
Problem Substances : Acrylamide
[+]

These findings for the first time demonstrate that the neuromodulatory propensity of geraniol is indeed comparable to that of curcumin.Nov 04, 2014

Pubmed Data : Chem Biol Interact. 2014 Nov 5 ;223:27-37. Epub 2014 Sep 6. PMID: 25199698
Article Published Date : Nov 04, 2014
Study Type : Animal Study
Additional Links
Substances : Curcumin, Geraniol
Diseases : Acrylamide-induced toxicity, Neurodegenerative Diseases, Oxidative Stress
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Problem Substances : Acrylamide
[+]

These findings suggest that extract of Ginkgo biloba can mitigate neurotoxicity induced by acrylamide.Jul 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neural Regen Res. 2017 Aug ;12(8):1287-1293. PMID: 28966643
Article Published Date : Jul 31, 2017
Study Type : Animal Study
Additional Links
Substances : Ginkgo biloba
Diseases : Acrylamide-induced toxicity
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Hippocampus Regeneration, Plant Extracts
Problem Substances : Acrylamide
[+]

Thymoquinone exhibited protective effects against ACR-induced neurotoxicity in Wistar rats through reduction of lipid peroxidation in cerebral cortex.Nov 30, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Basic Med Sci. 2014 Dec ;17(12):1007-11. PMID: 25859305
Article Published Date : Nov 30, 2014
Study Type : Animal Study
Additional Links
Substances : Thymoquinone
Diseases : Acrylamide-induced toxicity, Lipid Peroxidation, Oxidative Stress
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Acrylamide
[+]

Thymoquinone has neuroprotective effects against acrylamide.Feb 05, 2019

Pubmed Data : Neurochem Res. 2019 Feb 6. Epub 2019 Feb 6. PMID: 30725239
Article Published Date : Feb 05, 2019
Study Type : Animal Study
Additional Links
Substances : Thymoquinone
Diseases : Acrylamide-induced toxicity
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Neuroprotective Agents
Problem Substances : Acrylamide
[+]

Vitamin C administration could be used to reduce acrylamide-induced neurotoxicity.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Basic Clin Neurosci. 2018 Jan-Feb;9(1):27-34. PMID: 29942437
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Vitamin C
Diseases : Acrylamide-induced toxicity
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Acrylamide
[+]

Vitexin inhibits acrylamide-induced neuroinflammation and improves behavioral changes.May 30, 2019

Pubmed Data : Neurotoxicol Teratol. 2019 May 31 ;74:106811. Epub 2019 May 31. PMID: 31158445
Article Published Date : May 30, 2019
Study Type : Animal Study
Additional Links
Substances : Vitexins
Diseases : Acrylamide-induced toxicity, Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents
Problem Substances : Acrylamide
[+]

Acrylamide and its analogues exhibit mutagenicity in vitro.Dec 01, 1985

Pubmed Data : Mutat Res. 1985 Dec;158(3):129-33. PMID: 3908926
Article Published Date : Dec 01, 1985
Study Type : In Vitro Study
Additional Links
Problem Substances : Acrylamide
Adverse Pharmacological Actions : Mutagenic
[+]

Allicin alleviated acrylamide-induced NLRP3 inflammasome activation.Jan 31, 2021

Pubmed Data : Food Chem Toxicol. 2021 Feb ;148:111937. Epub 2020 Dec 24. PMID: 33348049
Article Published Date : Jan 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Allicin
Diseases : Acrylamide-induced toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-18 down-regulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Acrylamide
[+]

Allicin alleviates acrylamide-induced oxidative stress in BRL-3A cells.Jun 07, 2019

Pubmed Data : Life Sci. 2019 Jun 8:116550. Epub 2019 Jun 8. PMID: 31185235
Article Published Date : Jun 07, 2019
Study Type : In Vitro Study
Additional Links
Substances : Allicin
Diseases : Acrylamide-induced toxicity, Oxidative Stress
Pharmacological Actions : Antioxidants
Problem Substances : Acrylamide
[+]

An in vitro approach to protective effect of lactoferrin on acrylamide-induced oxidative damage.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : An Acad Bras Cienc. 2022 ;94(suppl 3):e20201882. Epub 2022 Dec 5. PMID: 36477225
Article Published Date : Dec 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Lactoferrin
Diseases : Acrylamide-induced toxicity, Oxidative Stress
Pharmacological Actions : Antioxidants, Catalase Up-Regulation, Superoxide Dismutase Up-regulation
Problem Substances : Acrylamide
[+]

Carnosic acid protected retinal pigment epithelium cells from acrylamide-induced toxicity.Sep 30, 2017

Pubmed Data : Food Chem Toxicol. 2017 Oct ;108(Pt B):543-553. Epub 2017 Feb 1. PMID: 28159594
Article Published Date : Sep 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Carnosic Acid
Diseases : Acrylamide-induced toxicity
Pharmacological Actions : Antioxidants
Additional Keywords : Acrylamide-induced toxicity, Antioxidants, Carnosic Acid
Problem Substances : Acrylamide
[+]

Catechins protect against acrylamide- and glycidamide-induced cellular toxicity.Jun 19, 2022

Pubmed Data : Food Chem Toxicol. 2022 Jun 20:113253. Epub 2022 Jun 20. PMID: 35738327
Article Published Date : Jun 19, 2022
Study Type : In Vitro Study
Additional Links
Substances : Catechin
Diseases : Acrylamide-induced toxicity
Pharmacological Actions : Anti-Apoptotic, Cytoprotective
Problem Substances : Acrylamide
[+]

EGCG fortification is a feasible method to decreased acrylamide formation in baked bread by 37%.Feb 28, 2018

Pubmed Data : Food Chem. 2018 Mar 1 ;242:162-168. Epub 2017 Sep 12. PMID: 29037673
Article Published Date : Feb 28, 2018
Study Type : In Vitro Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Acrylamide-induced toxicity
Problem Substances : Acrylamide
[+]

Food contaminant acrylamide increases inflammation in breast cells.Jan 31, 2011

Pubmed Data : Toxicol Ind Health. 2011 Feb ;27(1):11-8. Epub 2010 Aug 16. PMID: 20713430
Article Published Date : Jan 31, 2011
Study Type : In Vitro Study
Additional Links
Diseases : Breast Cancer: Prevention
Pharmacological Actions : Cyclooxygenase 2 Inhibitors
Problem Substances : Acrylamide
Adverse Pharmacological Actions : Cycloogenase-2 enzyme upregulation, Inflammatory, iNOS upregulation
[+]

Gastrointestinal digestion increased the ability of blackberry extract to inhibit acrylamide induced oxidative stress in HepG2 cells.Jan 12, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2017 Jan 13 ;7:40514. Epub 2017 Jan 13. PMID: 28084406
Article Published Date : Jan 12, 2017
Study Type : In Vitro Study
Additional Links
Substances : Blackberry
Diseases : Chemically-Induced Liver Damage
Pharmacological Actions : Antioxidants, Catalase Up-Regulation, Hepatoprotective, Superoxide Dismutase Up-regulation
Problem Substances : Acrylamide
[+]

Mitochondrial, lysosomal and DNA damages induced by acrylamide attenuate by ellagic acid in human lymphocyte.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2021 ;16(2):e0247776. Epub 2021 Feb 26. PMID: 33635915
Article Published Date : Dec 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Ellagic Acid
Diseases : Acrylamide-induced toxicity, DNA damage
Pharmacological Actions : Antioxidants, Genoprotective
Problem Substances : Acrylamide
[+]

Mulberry provides potent protection against acrylamide-induced oxidative stress.Aug 31, 2017

Pubmed Data : Food Chem. 2017 Sep 1 ;230:306-315. Epub 2017 Mar 9. PMID: 28407916
Article Published Date : Aug 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Anthocyanins, Mulberry
Diseases : Acrylamide-induced toxicity, Oxidative Stress
Pharmacological Actions : Antioxidants
Problem Substances : Acrylamide
[+]

Protective effect of Aronia melanocarpa juice against acrylamide-induced cellular toxicity.Feb 02, 2023

Pubmed Data : J Environ Sci Health B. 2023 Feb 3:1-11. Epub 2023 Feb 3. PMID: 36734814
Article Published Date : Feb 02, 2023
Study Type : In Vitro Study
Additional Links
Substances : Chokeberry
Diseases : Acrylamide-induced toxicity
Pharmacological Actions : Cytoprotective
Problem Substances : Acrylamide
[+]

Resveratrol could be a promising compound in suppressing acrylamide-induced hepatotoxicity and balancing the circadian clock.Aug 06, 2019

Pubmed Data : J Agric Food Chem. 2019 Aug 7 ;67(31):8510-8519. Epub 2019 Jul 24. PMID: 31294559
Article Published Date : Aug 06, 2019
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol
Diseases : Acrylamide-induced toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Nrf2 activation
Problem Substances : Acrylamide
[+]

Rosmarinic acid attenuates acrylamide induced apoptosis of BRL-3A cells.Apr 30, 2021

Pubmed Data : Food Chem Toxicol. 2021 May ;151:112156. Epub 2021 Mar 26. PMID: 33781805
Article Published Date : Apr 30, 2021
Study Type : In Vitro Study
Additional Links
Substances : Rosemaric Acid
Diseases : Acrylamide-induced toxicity
Pharmacological Actions : Anti-Apoptotic, Antioxidants
Problem Substances : Acrylamide
[+]

Silymarin can effectively alleviate acrylamide induced neurotoxicity in PC12 cells.Mar 31, 2017

Pubmed Data : Food Chem Toxicol. 2017 Apr ;102:93-101. Epub 2017 Jan 27. PMID: 28137608
Article Published Date : Mar 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Silymarin
Diseases : Acrylamide-induced toxicity
Pharmacological Actions : Antioxidants, Glutathione Upregulation , Malondialdehyde Down-regulation, Neuroprotective Agents, Nrf2 activation
Problem Substances : Acrylamide
[+]

The effects of thymoquinone and quercetin on the toxicity of acrylamide in rat glioma cells.Feb 20, 2022

Pubmed Data : J Biochem Mol Toxicol. 2022 Feb 21:e22992. Epub 2022 Feb 21. PMID: 35187760
Article Published Date : Feb 20, 2022
Study Type : In Vitro Study
Additional Links
Substances : Quercetin, Thymoquinone
Diseases : Acrylamide-induced toxicity
Pharmacological Actions : Antioxidants, Autophagy Inhibitors, Nrf2 activation
Problem Substances : Acrylamide
[+]

This review concludes the effects of plant polyphenols in acrylamide formation and elimination.Oct 31, 2015

Pubmed Data : Food Chem. 2015 Nov 1 ;186:46-53. Epub 2015 Apr 4. PMID: 25976790
Article Published Date : Oct 31, 2015
Study Type : Review
Additional Links
Substances : Polyphenols
Diseases : Acrylamide-induced toxicity
Problem Substances : Acrylamide
[+]

Thymoquinone protected against acrylamide-mediated neurotoxicity.Nov 13, 2019

Pubmed Data : Neurochem Res. 2019 Nov 14. Epub 2019 Nov 14. PMID: 31728856
Article Published Date : Nov 13, 2019
Study Type : In Vitro Study
Additional Links
Substances : Thymoquinone
Diseases : Acrylamide-induced toxicity
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Neuroprotective Agents
Problem Substances : Acrylamide
[+]

Trans-unsaturated fatty acids and acrylamide in food appear to contribute to atherosclerosis progression.Jan 01, 2003

Pubmed Data : Acta Microbiol Pol. 2003 ;52 Suppl:75-81. PMID: 15058816
Article Published Date : Jan 01, 2003
Study Type : Review
Additional Links
Diseases : Atherosclerosis, Cardiovascular Diseases
Problem Substances : Acrylamide , Trans Fatty Acids
Adverse Pharmacological Actions : Cardiotoxic
[+]

Wasabi roots and leaves are effective ingredients for inhibiting the formation and genotoxicity of acrylamide.Sep 26, 2016

Pubmed Data : J Sci Food Agric. 2016 Sep 27. Epub 2016 Sep 27. PMID: 27670634
Article Published Date : Sep 26, 2016
Study Type : In Vitro Study
Additional Links
Substances : Wasabi
Diseases : Cancers: All
Pharmacological Actions : Anticarcinogenic Agents, Genoprotective
Problem Substances : Acrylamide

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