Allopurinol

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9 Diseases Researched for Allopurinol

Name	AC	CK	Focus
Drug-Induced Toxicity	3	21
Eosinophilia	1	10
Liver Failure: Drug Induced	1	10
Aplastic Anemia	1	3
Hyperuricemia	2	3
Kidney Failure: Chronic	1	3
Uric Acid Nephropathy	1	2
Aspirin-Induced Toxicity	1	1
Hypersensitivity	1	1

1 Adverse Pharmacological Actions Researched for Allopurinol

Name	AC	CK	Focus
Hepatotoxic	1	10

Research Articles 7
Cumulative Knowledge Score 11
Overall Research Rating GOOD

View the Evidence:
7 Abstracts with Allopurinol Research

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Allopurinol use has been associated with Drug Rash with Eoinophilia and Sytematic Symptoms (DRESS syndrome).Oct 01, 2005

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Pubmed Data : Isr Med Assoc J. 2005 Oct;7(10):656-60. PMID: 16259349

Article Published Date : Oct 01, 2005

Study Type : Human Study

Additional Links

Diseases : Eosinophilia

Problem Substances : Allopurinol

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Allopurinol-induced hypersensitivity syndrome resulting in death has been reported.Apr 01, 2010

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Pubmed Data : Med Klin (Munich). 2010 Apr;105(4):262-6. PMID: 20455046

Article Published Date : Apr 01, 2010

Study Type : Human Study

Additional Links

Diseases : Drug-Induced Toxicity

Problem Substances : Allopurinol

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Fatal liver necrosis due to allopurinol has been reported.Dec 01, 1998

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Pubmed Data : Acta Med Port. 1998 Dec;11(12):1141-4. PMID: 10192993

Article Published Date : Dec 01, 1998

Study Type : Human Study

Additional Links

Diseases : Drug-Induced Toxicity , Liver Failure: Drug Induced

Problem Substances : Allopurinol

Adverse Pharmacological Actions : Hepatotoxic

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Allopurinol induced aplastic anemia in a patient with chronic renal failure.Jul 31, 1990

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Pubmed Data : Ryumachi. 1990 Aug ;30(4):281-6. PMID: 2287969

Article Published Date : Jul 31, 1990

Study Type : Human: Case Report

Additional Links

Diseases : Aplastic Anemia, Kidney Failure: Chronic

Problem Substances : Allopurinol

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"Tanshinone IIA prevents uric acid nephropathy in rats through NF-κB inhibition."May 31, 2012

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Pubmed Data : Planta Med. 2012 Jun ;78(9):866-73. Epub 2012 May 15. PMID: 22588836

Article Published Date : May 31, 2012

Study Type : Animal Study

Additional Links

Substances : Tanshinone IIA

Diseases : Hyperuricemia, Uric Acid Nephropathy

Pharmacological Actions : NF-kappaB Inhibitor

Additional Keywords : Drug: Allopurinol, Natural Substances Versus Drugs

Problem Substances : Allopurinol

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"Pharmacology of drugs for hyperuricemia. Mechanisms, kinetics and interactions."Dec 31, 2004

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Pubmed Data : Contrib Nephrol. 2005 ;147:35-46. PMID: 15604604

Article Published Date : Dec 31, 2004

Study Type : Review

Additional Links

Diseases : Hyperuricemia

Problem Substances : Allopurinol, Probenecid, Rasburicase

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HLA-related and other genetic markers involved in severe hypersensitivity reactions to aspirin and other drugsJul 31, 2010

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Pubmed Data : Curr Opin Allergy Clin Immunol. 2010 Aug ;10(4):280-90. PMID: 20485159

Article Published Date : Jul 31, 2010

Study Type : Review

Additional Links

Diseases : Aspirin-Induced Toxicity , Drug-Induced Toxicity , Hypersensitivity

Problem Substances : Allopurinol, Antibiotics, Aspirin

Research Articles 7
Cumulative Knowledge Score 11
Overall Research Rating GOOD

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