Aluminum Chloride

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19 Diseases Researched for Aluminum Chloride
NameACCKFocus
Aluminum Toxicity 50104Locked
Alzheimer's Disease1632Locked
Oxidative Stress1121Locked
Breast Cancer38Locked
Lipid Peroxidation48Locked
Neurodegenerative Diseases48Locked
Cancer Metastasis27Locked
Brain: Oxidative Stress36Locked
Breast Cancer: Triple Negative 15Locked
Cognitive Decline/Dysfunction24Locked
DNA damage24Locked
Memory Disorders24Locked
Anxiety12Locked
Brain Inflammation 12Locked
Chemotherapy and Radiation Toxicity12Locked
Fluoride Toxicity 12Locked
Neurodevelopmental Disorders12Locked
Parkinson's Disease12Locked
Osteoporosis11Locked
5 Adverse Pharmacological Actions Researched for Aluminum Chloride
NameACCKFocus
Neurotoxic36Locked
Inflammatory15Locked
Genotoxic12Locked
Renotoxic12Locked
Carcinogenic11Locked

View the Evidence:
74 Abstracts with Aluminum Chloride Research

[+]

Aluminum could increase the migration of human breast cancer cells irrespective of their oestrogen responsiveness.Sep 07, 2015

Pubmed Data : J Inorg Biochem. 2015 Sep 8. Epub 2015 Sep 8. PMID: 26365320
Article Published Date : Sep 07, 2015
Study Type : Human In Vitro
Additional Links
Diseases : Aluminum Toxicity , Breast Cancer, Breast Cancer: Triple Negative , Cancer Metastasis
Additional Keywords : Risk Factors
Problem Substances : Aluminum, Aluminum Chloride, Antiperspirants
[+]

Aluminum induces inflammatory and proteolytic alterations in human monocytic cell line.Sep 20, 2015

Pubmed Data : J Inorg Biochem. 2015 Sep 21. Epub 2015 Sep 21. PMID: 26421828
Article Published Date : Sep 20, 2015
Study Type : Human In Vitro
Additional Links
Diseases : Aluminum Toxicity
Problem Substances : Aluminum, Aluminum Chloride
Adverse Pharmacological Actions : Inflammatory
[+]

6-shogaol and could be a cost-effective candidate for the prevention and treatment of urolithiasis.May 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Saudi J Biol Sci. 2021 Jun ;28(6):3418-3423. Epub 2021 Mar 14. PMID: 34121880
Article Published Date : May 31, 2021
Study Type : Animal Study
Additional Links
Substances : 6-Shogaol
Diseases : Aluminum Toxicity , Kidney Damage: Chemically-Induced, Urolithiasis
Pharmacological Actions : Renoprotective
Problem Substances : Aluminum Chloride
[+]

A combination of resveratrol and curcumin is effective against aluminum chloride-induced neuroinflammation in rats.Feb 06, 2017

Pubmed Data : J Alzheimers Dis. 2017 Feb 7. Epub 2017 Feb 7. PMID: 28222524
Article Published Date : Feb 06, 2017
Study Type : Animal Study
Additional Links
Substances : Curcumin, Resveratrol
Diseases : Aluminum Toxicity , Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
Additional Keywords : Natural Substance Synergy
Problem Substances : Aluminum Chloride
[+]

Acute aluminum chloride toxicity revisited.Jan 14, 2019

Pubmed Data : Life Sci. 2019 Jan 15 ;217:202-211. Epub 2018 Dec 5. PMID: 30528774
Article Published Date : Jan 14, 2019
Study Type : Animal Study
Additional Links
Diseases : DNA damage, Oxidative Stress
Problem Substances : Aluminum Chloride
Adverse Pharmacological Actions : Neurotoxic
[+]

Aluminium chloride impairs long-term memory in rats.Sep 01, 2014

Pubmed Data : Toxicology. 2014 Sep 2 ;323:95-108. Epub 2014 Jun 25. PMID: 24973631
Article Published Date : Sep 01, 2014
Study Type : Animal Study
Additional Links
Diseases : Aluminum Toxicity , Memory Disorders
Additional Keywords : Aluminum Chloride, aluminum toxicity, Memory Disorders
Problem Substances : Aluminum Chloride
[+]

Aluminium salts could be environmental breast carcinogens.Dec 14, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Cancer. 2016 Dec 15 ;139(12):2781-2790. Epub 2016 Sep 7. PMID: 27541736
Article Published Date : Dec 14, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Diseases : Aluminum Toxicity , Breast Cancer, Cancer Metastasis
Pharmacological Actions : Anti-metastatic
Problem Substances : Aluminum Chloride
[+]

Aluminum chloride exposure may cause embryonic developmental disorder in zebrafish and ab-normal neurobehaviour in juvenile fish.Mar 19, 2017

Pubmed Data : Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2017 Mar 20 ;35(3):166-170. PMID: 28511298
Article Published Date : Mar 19, 2017
Study Type : Animal Study
Additional Links
Diseases : Aluminum Toxicity , Neurodevelopmental Disorders
Problem Substances : Aluminum Chloride
[+]

Aluminum chloride presents genotoxic potential and is potentially a cause of pathological disorders.Feb 02, 2017

Pubmed Data : Chemosphere. 2017 Feb 3 ;175:130-137. Epub 2017 Feb 3. PMID: 28211326
Article Published Date : Feb 02, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Diseases : Aluminum Toxicity
Problem Substances : Aluminum Chloride
Adverse Pharmacological Actions : Genotoxic
[+]

Aluminum chloride-induced amyloid β accumulation and endoplasmic reticulum stress in rat brain are averted by melatonin.Oct 28, 2020

Pubmed Data : Food Chem Toxicol. 2020 Oct 29 ;146:111829. Epub 2020 Oct 29. PMID: 33130240
Article Published Date : Oct 28, 2020
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Aluminum Toxicity , Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Aluminum Chloride
[+]

Aluminum overload increases oxidative stress in four functional brain areas of neonatal ratsMay 20, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Biomed Sci. 2012 May 21 ;19:51. Epub 2012 May 21. PMID: 22613782
Article Published Date : May 20, 2012
Study Type : Animal Study
Additional Links
Diseases : Aluminum Toxicity , Oxidative Stress
Problem Substances : Aluminum Chloride
[+]

An apple polyphenol extract plays a role in the reduction of the toxic effects from aluminum chloride in rats.Jan 31, 2014

Pubmed Data : Can J Physiol Pharmacol. 2014 Feb ;92(2):109-16. Epub 2014 Jan 29. PMID: 24502633
Article Published Date : Jan 31, 2014
Study Type : Animal Study
Additional Links
Substances : Apple Polyphenols
Diseases : Aluminum Toxicity , Oxidative Stress
Pharmacological Actions : Hepatoprotective
Problem Substances : Aluminum Chloride
[+]

Aqeuous Lawsonia Inermis leaf extract alleviated aluminum-induced oxidative stress.Apr 29, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : JBRA Assist Reprod. 2019 Apr 30 ;23(2):117-122. Epub 2019 Apr 30. PMID: 30875169
Article Published Date : Apr 29, 2019
Study Type : Animal Study
Additional Links
Substances : Henna
Diseases : Aluminum Toxicity
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Problem Substances : Aluminum Chloride
[+]

Asiatic acid attenuates aluminium chloride-induced behavioral changes, neuronal loss and astrocyte activation.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Metab Brain Dis. 2022 08 ;37(6):1773-1785. Epub 2022 May 13. PMID: 35554794
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Asiatic Acid
Diseases : Aluminum Toxicity , Neurodegenerative Diseases, Oxidative Stress
Pharmacological Actions : Antioxidants, Neuroprotective Agents, Superoxide Dismutase Up-regulation
Problem Substances : Aluminum Chloride
[+]

Asiatic acid could be able to modulate various pathological features of Alzheimer's disease and could hold promise in its treatment.Jan 21, 2019

Pubmed Data : Neurotox Res. 2019 Jan 22. Epub 2019 Jan 22. PMID: 30671870
Article Published Date : Jan 21, 2019
Study Type : Animal Study
Additional Links
Substances : Asiatic Acid
Diseases : Aluminum Toxicity , Alzheimer's Disease
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Neuroprotective Agents
Problem Substances : Aluminum Chloride
[+]

Astaxanthin improves aluminum-induced impaired memory performances.Apr 14, 2016

Pubmed Data : Eur J Pharmacol. 2016 Apr 15 ;777:60-9. Epub 2016 Feb 27. PMID: 26927754
Article Published Date : Apr 14, 2016
Study Type : Animal Study
Additional Links
Substances : Astaxanthin
Diseases : Aluminum Toxicity , Brain: Oxidative Stress, Cognitive Decline/Dysfunction
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Aluminum Chloride
[+]

Bacopa monnieri alleviates aluminium chloride-induced anxiety.Jul 12, 2020

Pubmed Data : J Basic Clin Physiol Pharmacol. 2020 Jul 13. Epub 2020 Jul 13. PMID: 32651984
Article Published Date : Jul 12, 2020
Study Type : Animal Study
Additional Links
Substances : Bacopa
Diseases : Aluminum Toxicity , Alzheimer's Disease, Anxiety
Pharmacological Actions : Anti-Anxiety Agents
Problem Substances : Aluminum Chloride
[+]

Black pepper significantly improved memory in aluminum chloride induced neurotoxicity mouse model.Dec 31, 2015

Pubmed Data : Curr Pharm Biotechnol. 2016;17(11):962-73. PMID: 27396401
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Black Pepper
Diseases : Aluminum Toxicity , Neurodegenerative Diseases, Oxidative Stress
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : aluminum toxicity, Black Pepper, Neurodegenerative diseases, Neuroprotective Agents, oxidative stress, Plant Extracts
Problem Substances : Aluminum Chloride
[+]

Caffeine provides a significant neuroprotection against aluminum chloride induced neurotoxicity.Mar 06, 2018

Pubmed Data : Nutr Neurosci. 2018 Mar 7:1-8. Epub 2018 Mar 7. PMID: 29514562
Article Published Date : Mar 06, 2018
Study Type : Animal Study
Additional Links
Substances : Caffeine
Diseases : Aluminum Toxicity
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Aluminum Chloride
[+]

Celastrol and thymoquinone alleviate aluminum chloride-induced neurotoxicity.May 12, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2022 May 13 ;151:113072. Epub 2022 May 13. PMID: 35576663
Article Published Date : May 12, 2022
Study Type : Animal Study
Additional Links
Substances : Celastrol, Thymoquinone
Diseases : Neurodegenerative Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Aluminum Chloride
[+]

Chronic caffeine consumption has a potentially good protective effect against Alzheimer's disease.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Clin Exp Pathol. 2015 ;8(7):7710-28. Epub 2015 Jul 1. PMID: 26339337
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Caffeine
Diseases : Aluminum Toxicity
Pharmacological Actions : Brain-derived neurotrophic factor modulator, Neuroprotective Agents
Problem Substances : Aluminum Chloride
[+]

Differential neuroprotective effect of curcuminoid formulations in aluminum chloride-induced Alzheimer's disease.May 06, 2022

Pubmed Data : Environ Sci Pollut Res Int. 2022 May 7. Epub 2022 May 7. PMID: 35525893
Article Published Date : May 06, 2022
Study Type : Animal Study
Additional Links
Substances : Turmeric
Diseases : Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Aluminum Chloride
[+]

Effects of baicalein with memantine on aluminium chloride-induced neurotoxicity.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2023 ;14:1034620. Epub 2023 Feb 22. PMID: 36909151
Article Published Date : Dec 31, 2022
Study Type : Animal Study
Additional Links
Diseases : Aluminum Toxicity
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Aluminum Chloride
[+]

Effects of Phoenix dactylifera against Streptozotocin-aluminium chloride induced Alzheimer's.Dec 31, 2022

Pubmed Data : Biomed Res Int. 2023 ;2023:1725638. Epub 2023 Jan 9. PMID: 36654869
Article Published Date : Dec 31, 2022
Study Type : Animal Study
Additional Links
Substances : Dates
Diseases : Aluminum Toxicity , Alzheimer's Disease
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Additional Keywords : Plant Extracts
Problem Substances : Aluminum Chloride
[+]

EGCG nanoparticles attenuate aluminum chloride induced neurobehavioral deficits.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Aging Neurosci. 2018 ;10:244. Epub 2018 Aug 13. PMID: 30150930
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Aluminum Toxicity , Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Aluminum Chloride
[+]

Ethyl acetate leaf fraction of Tamarindus indica was associated with some protective potential during prenatal aluminum chloride exposure.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Exp Pharmacol. 2022 ;14:275-289. Epub 2022 Oct 20. PMID: 36303592
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Tamarind
Diseases : Aluminum Toxicity , Prenatal Chemical Exposures
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Aluminum Chloride
[+]

Eugenol holds potential as a neuroprotective agent against aluminium induced brain toxicity.Feb 28, 2017

Pubmed Data : Arh Hig Rada Toksikol. 2017 Mar 1 ;68(1):27-37. PMID: 28365674
Article Published Date : Feb 28, 2017
Study Type : Animal Study
Additional Links
Substances : Eugenol
Diseases : Aluminum Toxicity
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Neuroprotective Agents
Additional Keywords : aluminum toxicity, Anti-Apoptotic, Antioxidants, eugenol, Neuroprotective Agents
Problem Substances : Aluminum Chloride
[+]

Evaluation of anti-Alzheimer activity of Echinacea purpurea extracts in aluminum chloride-induced neurotoxicity.Feb 28, 2023

Pubmed Data : J Chem Neuroanat. 2023 Mar ;128:102234. Epub 2023 Jan 11. PMID: 36640914
Article Published Date : Feb 28, 2023
Study Type : Animal Study
Additional Links
Substances : Echinacea
Diseases : Aluminum Toxicity , Alzheimer's Disease
Additional Keywords : Plant Extracts
Problem Substances : Aluminum Chloride
[+]

Extra virgin olive oil might provide a basis for developing a new dietary supplementation strategy in order to prevent lung tissue damage.Jul 03, 2016

Pubmed Data : Environ Sci Pollut Res Int. 2016 Jul 4. Epub 2016 Jul 4. PMID: 27378219
Article Published Date : Jul 03, 2016
Study Type : Animal Study
Additional Links
Substances : Olive Oil
Diseases : DNA damage, Oxidative Stress
Pharmacological Actions : Cytoprotective
Problem Substances : Acrylamide , Aluminum Chloride
[+]

Fenugreek seed powder attenuated aluminum chloride-induced tau pathology, oxidative stress, and inflammation.Feb 24, 2017

Pubmed Data : J Alzheimers Dis. 2017 Feb 25. Epub 2017 Feb 25. PMID: 28269780
Article Published Date : Feb 24, 2017
Study Type : Animal Study
Additional Links
Substances : Fenugreek
Diseases : Aluminum Toxicity , Alzheimer's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
Problem Substances : Aluminum Chloride
[+]

Fenugreek seed powder nullified aluminium chloride induced memory loss.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2016 ;11(11):e0165955. Epub 2016 Nov 28. PMID: 27893738
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Fenugreek
Diseases : Aluminum Toxicity , Alzheimer's Disease, Memory Disorders
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Aluminum Chloride
[+]

Fisetin exerts neuroprotection against aluminum chloride induced brain pathology.Feb 28, 2013

Pubmed Data : Neuromolecular Med. 2013 Mar ;15(1):192-208. Epub 2013 Jan 13. PMID: 23315010
Article Published Date : Feb 28, 2013
Study Type : Animal Study
Additional Links
Substances : Fisetin
Diseases : Aluminum Toxicity , Lipid Peroxidation
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Additional Keywords : aluminum toxicity, Antioxidants, Fisetin, Lipid Peroxidation, Neuroprotective Agents
Problem Substances : Aluminum Chloride
[+]

Fisetin may slow or prevent neurodegneration and can be utilised as neuroprotective agent against Alzheimer's and Parkinson's disease.Aug 07, 2015

Pubmed Data : J Nutr Biochem. 2015 Aug 8. Epub 2015 Aug 8. PMID: 26411262
Article Published Date : Aug 07, 2015
Study Type : Animal Study
Additional Links
Substances : Fisetin
Diseases : Aluminum Toxicity , Alzheimer's Disease, Neurodegenerative Diseases, Parkinson's Disease
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents
Problem Substances : Aluminum Chloride
Adverse Pharmacological Actions : Neurotoxic
[+]

Gallic and hesperidin ameliorate electrolyte imbalances in AlCl3-induced nephrotoxicity.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biochem Res Int. 2022 ;2022:6151684. Epub 2022 Oct 10. PMID: 36263197
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Gallic Acid, Hesperidin
Diseases : Aluminum Toxicity , Kidney Damage: Chemically-Induced
Pharmacological Actions : Renoprotective
Problem Substances : Aluminum Chloride
[+]

Ginkgo biloba extract alleviates oxidative stress and some neurotransmitters changes induced by aluminum chloride in rats.Feb 28, 2017

Pubmed Data : Nutrition. 2017 Mar ;35:93-99. Epub 2016 Oct 26. PMID: 28241996
Article Published Date : Feb 28, 2017
Study Type : Animal Study
Additional Links
Substances : Ginkgo biloba
Diseases : Aluminum Toxicity
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Additional Keywords : Plant Extracts
Problem Substances : Aluminum Chloride
[+]

Ginkgo biloba extract mitigates the neurotoxicity of AlCl 3 in Alzheimer rat's model.May 29, 2022

Pubmed Data : Int J Neurosci. 2022 May 30:1-16. Epub 2022 May 30. PMID: 35634646
Article Published Date : May 29, 2022
Study Type : Animal Study
Additional Links
Substances : Ginkgo biloba
Diseases : Aluminum Toxicity , Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Aluminum Chloride
[+]

Ginsenoside Rg3 alleviates aluminum chloride-induced bone impairment in rats.Nov 02, 2021

Pubmed Data : J Agric Food Chem. 2021 Nov 3 ;69(43):12634-12644. Epub 2021 Oct 25. PMID: 34694773
Article Published Date : Nov 02, 2021
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Ginsenosides
Diseases : Aluminum Toxicity
Pharmacological Actions : Osteoprotective , Transforming growth factor beta (TGF-β) upregulation
Problem Substances : Aluminum Chloride
[+]

Gotu kola could protect cognitive from impairments and morphological alterations caused by D-galactose and aluminium chloride toxicity.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2019 Jan ;109:853-864. Epub 2018 Nov 5. PMID: 30551539
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Gotu Kola
Diseases : Aluminum Toxicity
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Aluminum Chloride
[+]

Hepatoprotective potential of Tamarindus indica following prenatal aluminum exposure.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Toxicol Rep. 2023 ;10:376-381. Epub 2023 Mar 4. PMID: 36926661
Article Published Date : Dec 31, 2022
Study Type : Animal Study
Additional Links
Substances : Tamarind
Diseases : Aluminum Toxicity , Chemically-Induced Liver Damage, Prenatal Chemical Exposures
Pharmacological Actions : Hepatoprotective
Problem Substances : Aluminum Chloride
[+]

Hesperidin and silibinin exert neuroprotective effects against aluminum chloride induced cognitive impairment and neurochemical changes.May 27, 2015

Pubmed Data : Biol Trace Elem Res. 2015 May 28. Epub 2015 May 28. PMID: 26018497
Article Published Date : May 27, 2015
Study Type : Animal Study
Additional Links
Substances : Hesperidin, Silibinin
Diseases : Aluminum Toxicity
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Aluminum Chloride
[+]

Hesperidin might be a potent option for treating the symptoms of cognitive impairment in Alzheimer's disease.Apr 22, 2018

Pubmed Data : Neurotox Res. 2018 Apr 23. Epub 2018 Apr 23. PMID: 29687202
Article Published Date : Apr 22, 2018
Study Type : Animal Study
Additional Links
Substances : Hesperidin
Diseases : Aluminum Toxicity , Alzheimer's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
Problem Substances : Aluminum Chloride
[+]

Hypericum perforatum extract has neuroprotection actions against aluminum chloride-induced Alzheimer's disease like pathology.May 12, 2017

Pubmed Data : Biomed Pharmacother. 2017 May 13 ;91:931-937. Epub 2017 May 13. PMID: 28514831
Article Published Date : May 12, 2017
Study Type : Animal Study
Additional Links
Substances : St. Johns Wort
Diseases : Aluminum Toxicity , Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Aluminum Chloride
[+]

Mangiferin protects rats against aluminum chloride induced neurotoxicity.Jun 30, 2015

Pubmed Data : J Trace Elem Med Biol. 2015 Jul ;31:107-12. Epub 2015 Apr 22. PMID: 26004900
Article Published Date : Jun 30, 2015
Study Type : Animal Study
Additional Links
Substances : Mangiferin
Diseases : Aluminum Toxicity , Brain: Oxidative Stress, Cognitive Decline/Dysfunction
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Aluminum Chloride
[+]

Melatonin alleviates aluminium chloride-induced immunotoxicity.May 29, 2019

Pubmed Data : Ecotoxicol Environ Saf. 2019 May 30 ;173:131-141. Epub 2019 Feb 13. PMID: 30771656
Article Published Date : May 29, 2019
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Aluminum Toxicity , Oxidative Stress
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Nrf2 activation
Problem Substances : Aluminum Chloride
[+]

Mentha longifolia is a source of lead compounds and a promising food supplement protective against Alzheimer's disease.Feb 14, 2021

Pubmed Data : J Food Biochem. 2021 Feb 15:e13644. Epub 2021 Feb 15. PMID: 33587299
Article Published Date : Feb 14, 2021
Study Type : Animal Study
Additional Links
Substances : Mint
Diseases : Aluminum Toxicity , Alzheimer's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents, NF-kappaB Inhibitor
Problem Substances : Aluminum Chloride
[+]

Naringin regulates glutamate-nitric oxide cGMP pathway in ammonium chloride induced neurotoxicity.Nov 30, 2016

Pubmed Data : Biomed Pharmacother. 2016 Dec ;84:1717-1726. Epub 2016 Nov 9. PMID: 27836465
Article Published Date : Nov 30, 2016
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Aluminum Toxicity , Lipid Peroxidation, Neurodegenerative Diseases
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Problem Substances : Aluminum Chloride
[+]

Neuroprotective effects of phytochemicals against aluminum chloride-induced Alzheimer's Disease.Aug 16, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmaceuticals (Basel). 2022 Aug 17 ;15(8). Epub 2022 Aug 17. PMID: 36015156
Article Published Date : Aug 16, 2022
Study Type : Animal Study
Additional Links
Substances : Thymol, Thymoquinone
Diseases : Aluminum Toxicity , Alzheimer's Disease
Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Neuroprotective Agents, Nrf2 activation
Problem Substances : Aluminum Chloride
[+]

Neuroprotective role of Asiatic acid in aluminium chloride induced rat model of Alzheimer's disease.Dec 31, 2017

Pubmed Data : Front Biosci (Schol Ed). 2018 01 1 ;10:262-275. Epub 2018 Jan 1. PMID: 28930532
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Gotu Kola
Diseases : Aluminum Toxicity , Oxidative Stress
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents
Problem Substances : Aluminum Chloride
[+]

Nootropic effect of neferine on aluminium chloride-induced Alzheimer's disease in experimental models. Jan 31, 2020

Pubmed Data : J Biochem Mol Toxicol. 2020 Feb ;34(2):e22429. Epub 2019 Dec 20. PMID: 31860774
Article Published Date : Jan 31, 2020
Study Type : Animal Study
Additional Links
Substances : Lotus
Diseases : Aluminum Toxicity , Alzheimer's Disease, Lipid Peroxidation, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Aluminum Chloride
[+]

Opuntia ficus-indica might be promising candidate for treating Alzheimer disease.Sep 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Saudi J Biol Sci. 2020 Oct ;27(10):2829-2838. Epub 2020 Jul 9. PMID: 32994743
Article Published Date : Sep 30, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Aluminum Toxicity , Alzheimer's Disease
Pharmacological Actions : Acetylcholinesterase Inhibitor, Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Aluminum Chloride
[+]

Oral administration of Ellagic acid and Ferulic acid may ameliorate gamma radiation and aluminium chloride induced oxidative damage.Jul 15, 2016

Pubmed Data : Life Sci. 2016 Jul 16. Epub 2016 Jul 16. PMID: 27436544
Article Published Date : Jul 15, 2016
Study Type : Animal Study
Additional Links
Substances : Ellagic Acid, Ferulic acid
Diseases : Chemotherapy and Radiation Toxicity
Pharmacological Actions : Antioxidants, Catalase Up-Regulation, Glutathione Upregulation , Malondialdehyde Down-regulation, Superoxide Dismutase Up-regulation
Problem Substances : Aluminum Chloride
[+]

Piper nigrum significantly improved learning and memory deficits associated with aluminium chloride and also showed the anticholinesterase activity with prevention of nerve degeneration.Mar 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Clin Diagn Res. 2015 Apr ;9(4):FF01-4. Epub 2015 Apr 1. PMID: 26023568
Article Published Date : Mar 31, 2015
Study Type : Animal Study
Additional Links
Substances : Black Pepper
Diseases : Alzheimer's Disease
Pharmacological Actions : Acetylcholinesterase Inhibitor, Antioxidants, Neuroprotective Agents
Additional Keywords : Prevention
Problem Substances : Aluminum Chloride
[+]

Pomegranate juice rescues developmental, neurobehavioral and biochemical disorders in aluminum chloride-treated male mice.Dec 31, 2020

Pubmed Data : J Trace Elem Med Biol. 2021 Jan ;63:126655. Epub 2020 Sep 29. PMID: 33045674
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Pomegranate
Diseases : Aluminum Toxicity
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Problem Substances : Aluminum Chloride
[+]

Protective effect of resveratrol and tannic acid combination on aluminium chloride induced neurotoxicity.May 04, 2023

Pubmed Data : Nutr Neurosci. 2023 May 5:1-13. Epub 2023 May 5. PMID: 37144738
Article Published Date : May 04, 2023
Study Type : Animal Study
Additional Links
Substances : Resveratrol, Tannic Acid
Diseases : Aluminum Toxicity
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Aluminum Chloride
[+]

Quercetin and α-lipoic acid complemented each other in protecting the rat brain against oxidative stress induced by aluminium chloride.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Toxicol. 2018 ;2018:2817036. Epub 2018 May 16. PMID: 29861723
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Alpha-Lipoic Acid, Quercetin
Diseases : Aluminum Toxicity
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Natural Substance Synergy
Problem Substances : Aluminum Chloride
[+]

Quercetin stimulates the non-amyloidogenic pathway via activation of ADAM10 and ADAM17 gene expression in aluminum chloride-induced Alzheimer's disease.Sep 15, 2021

Pubmed Data : Life Sci. 2021 Sep 16 ;285:119964. Epub 2021 Sep 16. PMID: 34537230
Article Published Date : Sep 15, 2021
Study Type : Animal Study
Additional Links
Substances : Quercetin
Diseases : Aluminum Toxicity , Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Aluminum Chloride
[+]

Raisin have neuroprotective effects and improves the spatial memory in Alzheimer's disease animal models.Aug 15, 2017

Pubmed Data : Nutr Neurosci. 2017 Aug 16:1-9. Epub 2017 Aug 16. PMID: 28812474
Article Published Date : Aug 15, 2017
Study Type : Animal Study
Additional Links
Substances : Raisins
Diseases : Aluminum Toxicity , Alzheimer's Disease
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation, Neuroprotective Agents
Problem Substances : Aluminum Chloride
[+]

Resveratrol pre-administration to rats ameliorates renal damage and improves renal function in aluminum chloride intoxicated rats.Mar 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Saudi Med J. 2016 Apr ;37(4):369-78. PMID: 27052279
Article Published Date : Mar 31, 2016
Study Type : Animal Study
Additional Links
Substances : Resveratrol
Diseases : Aluminum Toxicity , Oxidative Stress
Pharmacological Actions : Antioxidants, Interleukin-6 Downregulation, Renoprotective, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Aluminum Chloride
[+]

Rosa damascena extract with its high antioxidant content is able to exert a protective effect against aluminum-induced oxidative stress.Apr 26, 2018

Pubmed Data : Biol Trace Elem Res. 2018 Apr 27. Epub 2018 Apr 27. PMID: 29704206
Article Published Date : Apr 26, 2018
Study Type : Animal Study
Additional Links
Substances : Rose
Diseases : Aluminum Toxicity , Oxidative Stress
Pharmacological Actions : Antioxidants
Additional Keywords : Plant Extracts
Problem Substances : Aluminum Chloride
[+]

Selenium helps to combat oxidative stress produced by accumulation of aluminum in the brain and helps in prophylaxis of Alzheimer's diseases.Apr 30, 2015

Pubmed Data : Biol Trace Elem Res. 2015 May ;165(1):67-74. Epub 2015 Jan 23. PMID: 25613582
Article Published Date : Apr 30, 2015
Study Type : Animal Study
Additional Links
Substances : Selenium
Diseases : Aluminum Toxicity , Lipid Peroxidation
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Risk Reduction
Problem Substances : Aluminum Chloride
[+]

Selenium was effective in preventing lung damage cause by aluminum chloride.Aug 22, 2016

Pubmed Data : Biol Trace Elem Res. 2016 Aug 23. Epub 2016 Aug 23. PMID: 27550156
Article Published Date : Aug 22, 2016
Study Type : Animal Study
Additional Links
Substances : Selenium
Diseases : Aluminum Toxicity
Pharmacological Actions : Antioxidants
Problem Substances : Aluminum Chloride
[+]

Silibinin-loaded nanostructured lipid carriers (NLCs) ameliorated cognitive deficits and oxidative damages.Dec 31, 2021

Pubmed Data : Toxicology. 2022 07 ;477:153260. Epub 2022 Jul 16. PMID: 35850386
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Silibinin
Diseases : Aluminum Toxicity , Neurodegenerative Diseases, Oxidative Stress
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Problem Substances : Aluminum Chloride
[+]

Synergistic oxidative impact of aluminum chloride and sodium fluoride exposure during early stages of brain development.Feb 19, 2019

Pubmed Data : Environ Sci Pollut Res Int. 2019 Feb 20. Epub 2019 Feb 20. PMID: 30788699
Article Published Date : Feb 19, 2019
Study Type : Animal Study
Additional Links
Diseases : Aluminum Toxicity , Brain: Oxidative Stress, Fluoride Toxicity
Additional Keywords : Synergistic Toxicity
Problem Substances : Aluminum Chloride, Sodium Fluoride
Adverse Pharmacological Actions : Neurotoxic
[+]

Synergistic potential of propolis and vitamin E against sub-acute toxicity of aluminum chloride.Jan 05, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Physiol Res. 2019 03 6 ;68(1):67-74. Epub 2018 Oct 23. PMID: 30433801
Article Published Date : Jan 05, 2019
Study Type : Animal Study
Additional Links
Substances : Bee Propolis, Vitamin E
Diseases : Aluminum Toxicity
Pharmacological Actions : Cytoprotective
Additional Keywords : Natural Substance Synergy
Problem Substances : Aluminum Chloride
[+]

Tamarindus indica ameliorates behavioral and cytoarchitectural changes in the cerebellar cortex following prenatal aluminum chloride exposure.Sep 29, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Anat Cell Biol. 2022 Sep 30 ;55(3):320-329. Epub 2022 Aug 25. PMID: 36002437
Article Published Date : Sep 29, 2022
Study Type : Animal Study
Additional Links
Substances : Tamarind
Diseases : Aluminum Toxicity , Prenatal Chemical Exposures
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Aluminum Chloride
[+]

Tannoid principles of E. officinalis may be a promising therapy in ameliorating neurotoxicity of aluminum.Apr 03, 2015

Pubmed Data : Nutr Neurosci. 2015 Apr 4. Epub 2015 Apr 4. PMID: 25842984
Article Published Date : Apr 03, 2015
Study Type : Animal Study
Additional Links
Substances : Amla Fruit
Diseases : Aluminum Toxicity , Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Significant Treatment Outcome
Problem Substances : Aluminum Chloride
[+]

The multifactorial role of vanillin in amelioration of aluminium chloride and D-galactose induced Alzheimer's disease.Sep 04, 2023

Pubmed Data : Eur J Pharmacol. 2023 Sep 5 ;954:175832. Epub 2023 Jun 16. PMID: 37329974
Article Published Date : Sep 04, 2023
Study Type : Animal Study
Additional Links
Substances : Vanillin
Diseases : Aluminum Toxicity , Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Aluminum Chloride
[+]

The possible neuroprotective effects of melatonin in aluminum chloride-induced neurotoxicity.Feb 03, 2019

Pubmed Data : Environ Sci Pollut Res Int. 2019 Feb 4. Epub 2019 Feb 4. PMID: 30719664
Article Published Date : Feb 03, 2019
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Aluminum Toxicity
Pharmacological Actions : Antioxidants, Neuroprotective Agents, Nrf2 activation
Problem Substances : Aluminum Chloride
[+]

This study indicates that aluminum chloride exposure induces oxidative stress and suppresses kidney function.Feb 23, 2016

Pubmed Data : Biol Trace Elem Res. 2016 Feb 24. Epub 2016 Feb 24. PMID: 26910335
Article Published Date : Feb 23, 2016
Study Type : Animal Study
Additional Links
Problem Substances : Aluminum Chloride
Adverse Pharmacological Actions : Renotoxic
[+]

Thymoquinone holds potential for neuroprotection and may be a promising approach for the treatment of neurodegenerative disorders.Mar 31, 2018

Pubmed Data : Neurol Res. 2018 Apr ;40(4):324-333. Epub 2018 Feb 21. PMID: 29464986
Article Published Date : Mar 31, 2018
Study Type : Animal Study
Additional Links
Substances : Thymoquinone
Diseases : Aluminum Toxicity , Alzheimer's Disease, Neurodegenerative Diseases
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Aluminum Chloride
[+]

Walnut protein hydrolysates play a protective role on neurotoxicity induced by d-galactose and aluminum chloride.Sep 09, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2018 Sep 10 ;23(9). Epub 2018 Sep 10. PMID: 30201912
Article Published Date : Sep 09, 2018
Study Type : Animal Study
Additional Links
Substances : Walnut
Diseases : Aluminum Toxicity
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Aluminum Chloride
[+]

β-sitosterol protects against aluminium chloride-mediated neurotoxicity.Mar 07, 2023

Pubmed Data : Curr Alzheimer Res. 2023 Mar 8. Epub 2023 Mar 8. PMID: 36892031
Article Published Date : Mar 07, 2023
Study Type : Animal Study
Additional Links
Substances : Stigmasterol
Diseases : Aluminum Toxicity
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Aluminum Chloride
[+]

Aluminium chloride promotes the growth of human mammary epithelial cells.Jan 06, 2012

Pubmed Data : J Appl Toxicol. 2012 Jan 6. Epub 2012 Jan 6. PMID: 22223356
Article Published Date : Jan 06, 2012
Study Type : In Vitro Study
Additional Links
Diseases : Aluminum Toxicity , Breast Cancer
Problem Substances : Aluminum Chloride, Antiperspirants
Adverse Pharmacological Actions : Carcinogenic
[+]

Ginsenoside Rb1 alleviates aluminum chloride-induced rat osteoblasts dysfunction.Aug 09, 2016

Pubmed Data : Toxicology. 2016 Aug 10 ;368-369:183-188. Epub 2016 Jul 25. PMID: 27470910
Article Published Date : Aug 09, 2016
Study Type : In Vitro Study
Additional Links
Substances : Ginsenosides
Diseases : Aluminum Toxicity , Osteoporosis, Oxidative Stress
Pharmacological Actions : Cytoprotective
Problem Substances : Aluminum Chloride

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Is Eating and Injecting Aluminum Safe as Our Regulators Say?
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Aluminum toxicity, a characteristically manmade problem, is now impossible to avoid, and has become a postmodern human rite of passage. Not only are we being exposed, daily, through environmental pollution in our water, soil and air, but many of our regulatory agencies consider it perfectly safe to intentionally consume or inject the stuff directly into our bodies

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