Anticoagulants

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41 Diseases Researched for Anticoagulants
NameACCKFocus
Intracerebral Hemorrhage6120Locked
Coronary Artery Disease790Locked
Intraventricular hemorrhage160Locked
Cerebral Microbleeds240Locked
Coronary Stenting 240Locked
Hemodialysis240Locked
Myocardial Infarction330Locked
Osteoporosis230Locked
Atrial Fibrillation321Locked
Cardiac Arrest120Locked
Cardiac Mortality 220Locked
Drug-Induced Toxicity 120Locked
Head Trauma120Locked
Intraocular Hemorrhage220Locked
Mortality: All-Cause120Locked
Stroke220Locked
Allergic Airway Diseases110Locked
Aortic Calcification110Locked
Arterial Calcification110Locked
Brain Injury: Traumatic110Locked
Brain Ischemia110Locked
Cardiovascular Diseases110Locked
Chemical Poisoning110Locked
Heart Attack110Locked
Intracranial Hemmorhage110Locked
Macular Degeneration110Locked
Prostate Cancer110Locked
Traumatic Brain Injury110Locked
Purple Toes Syndrome26Locked
Skin Necrosis24Locked
Cholesterol Microembolism13Locked
Hematoma: Retrobulbar13Locked
Intracapsular hemorrhage13Locked
Total Hip Arthroplasty13Locked
Breast Cancer12Locked
Cancer Mortality12Locked
Kidney Failure: Chronic12Locked
Vascular Calcification12Locked
Prenatal Chemical Exposures11Locked
Stroke: Prevention 11Locked
Thrombosis11Locked
4 Adverse Pharmacological Actions Researched for Anticoagulants
NameACCKFocus
Necrotic24Locked
Hemorrhagic 13Locked
Embryotoxic11Locked
Teratogenic11Locked
Related Topics

The Following are Sub-Topics of Anticoagulants

View the Evidence:
49 Abstracts with Anticoagulants Research

[+]

Vascular and valvular calcification are potential side effects of Vitamin K antagonists.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Cardiovasc Med. 2022 ;9:938567. Epub 2022 Aug 19. PMID: 36061545
Article Published Date : Dec 31, 2021
Study Type : Meta Analysis, Review
Additional Links
Diseases : Arterial Calcification, Vascular Calcification
Additional Keywords : Increased Risk
Problem Substances : Anticoagulants
[+]

In patients 5 or more microbleeds, the high risk and mortality of intracerebral hemorrhage seem to outweigh the modest benefit of antithrombotic agents.Nov 01, 2008

Pubmed Data : J Neurol. 2008 Nov;255(11):1679-86. Epub 2008 Dec 8. PMID: 19156486
Article Published Date : Nov 01, 2008
Study Type : Meta Analysis
Additional Links
Diseases : Cerebral Microbleeds, Intracerebral Hemorrhage
Problem Substances : Thrombolytics, Warfarin
[+]

Long-term use of warfarin was associated with osteoporotic fractures, at least in men with atrial fibrillation. Jan 23, 2006

Pubmed Data : Arch Intern Med. 2006 Jan 23;166(2):241-6. PMID: 16432096
Article Published Date : Jan 23, 2006
Study Type : Meta Analysis
Additional Links
Diseases : Drug-Induced Toxicity , Osteoporosis
Problem Substances : Warfarin
[+]

Preinjury warfarin worsens outcome in elderly patients who fall from standing.Jun 01, 2009

Pubmed Data : J Trauma. 2009 Jun;66(6):1518-22; discussion 1523-4. PMID: 19509609
Article Published Date : Jun 01, 2009
Study Type : Meta Analysis
Additional Links
Diseases : Head Trauma, Mortality: All-Cause
Problem Substances : Warfarin
[+]

The incidence of anticoagulant-associated intracerebral hemorrhage quintupled in our population during the 1990s. The majority of this change can be explained by increasing warfarin use. Jan 09, 2007

Pubmed Data : Neurology. 2007 Jan 9;68(2):116-21. PMID: 17210891
Article Published Date : Jan 09, 2007
Study Type : Meta Analysis
Additional Links
Diseases : Intracerebral Hemorrhage
Problem Substances : Anticoagulants, Warfarin
[+]

The use of thrombolytic medications to treat cardiac arrrest demonstrates a lack of benefit and potential harm.Dec 01, 2010

Pubmed Data : Ann Pharmacother. 2010 Dec;44(12):2007-13. Epub 2010 Nov 30. PMID: 21119096
Article Published Date : Dec 01, 2010
Study Type : Meta Analysis
Additional Links
Diseases : Cardiac Arrest
Problem Substances : Thrombolytics, Warfarin
[+]

Warfarin use is associated with an excess of cerebral microbleeds, a potential risk factor for intracerebral hemorrhage.Jan 01, 2011

Pubmed Data : Ann Vasc Surg. 2011 Jan;25(1):25-31. PMID: 20889291
Article Published Date : Jan 01, 2011
Study Type : Meta Analysis
Additional Links
Diseases : Cerebral Microbleeds, Intracerebral Hemorrhage
Problem Substances : Clopidogrel
[+]

Warfarin use was associated with larger initial intracerebral hemorrhage (ICH) volume which likely accounts for excess mortality in this group.Sep 30, 2008

Pubmed Data : Neurology. 2008 Sep 30;71(14):1084-9. PMID: 18824672
Article Published Date : Sep 30, 2008
Study Type : Meta Analysis
Additional Links
Diseases : Intracerebral Hemorrhage
Problem Substances : Warfarin
[+]

Warfarin-associated intraventricular hemorrhage is associated with higher mortality, especially in patients with panventricular involvement. Oct 01, 2007

Pubmed Data : Neurol Res. 2007 Oct;29(7):661-3. PMID: 18173903
Article Published Date : Oct 01, 2007
Study Type : Meta Analysis
Additional Links
Diseases : Intraventricular hemorrhage
Problem Substances : Anticoagulants, Clopidogrel, Thrombolytics, Warfarin
[+]

Activated charcoal could be used in rivaroxaban overdose and accidental ingestion to antagonise absorption.Jun 30, 2017

Pubmed Data : Clin Pharmacokinet. 2017 Jul ;56(7):793-801. PMID: 27910037
Article Published Date : Jun 30, 2017
Study Type : Human Study
Additional Links
Substances : Activated Charcoal
Diseases : Chemical Poisoning
Problem Substances : Anticoagulants
[+]

Among patients receiving clopidogrel following acute myocardial infarction, concomitant therapy with proton pump inhibitors other than pantoprazole was associated with a loss of the beneficial effects of clopidogrel and an increased risk of reinfarction.Mar 31, 2009

Pubmed Data : CMAJ. 2009 Mar 31;180(7):713-8. Epub 2009 Jan 28. PMID: 19176635
Article Published Date : Mar 31, 2009
Study Type : Human Study
Additional Links
Diseases : Myocardial Infarction
Problem Substances : Clopidogrel
[+]

Aspirin with or without chronic oral anticoagulant treatment does not reduce mortality or reinfarction, reduces stroke, but is associated with significantly more major bleeding. Mar 01, 2010

Pubmed Data : Am J Med. 2010 Mar;123(3):250-8. PMID: 20193834
Article Published Date : Mar 01, 2010
Study Type : Human Study
Additional Links
Diseases : Cardiac Mortality , Heart Attack
Problem Substances : Anticoagulants, Antiplatelet Drugs, Aspirin
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Clopidogrel in combination with proton pump inhibitors is associated with increased death and/or hospitalization due to myocardial infarction. Dec 08, 2009

Pubmed Data : Circulation. 2009 Dec 8;120(23):2322-9. Epub 2009 Nov 23. PMID: 19933932
Article Published Date : Dec 08, 2009
Study Type : Human Study
Additional Links
Diseases : Myocardial Infarction
Problem Substances : Clopidogrel
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Clopidogrel therapy in the absence of a loading dose is associated with a significantly higher risk of death or myocardial infarction.Jun 01, 2004

Pubmed Data : Minerva Cardioangiol. 2004 Jun;52(3):195-208. PMID: 15194981
Article Published Date : Jun 01, 2004
Study Type : Human Study
Additional Links
Diseases : Cardiac Mortality , Coronary Artery Disease
Problem Substances : Clopidogrel
[+]

Clopidopgrel use before an acute coronary syndrome had a higher rate of major adverse cardiovascular events than patients who were not. Jun 01, 2009

Pubmed Data : Catheter Cardiovasc Interv. 2009 Jun 1;73(7):866-70. PMID: 19198009
Article Published Date : Jun 01, 2009
Study Type : Human Study
Additional Links
Diseases : Cardiovascular Diseases, Coronary Artery Disease, Myocardial Infarction
Problem Substances : Clopidogrel
[+]

Combination therapy with aspirin, clopidogrel and warfarin following coronary stenting is associated with a significant risk of bleeding.Apr 01, 2006

Pubmed Data : J Invasive Cardiol. 2006 Apr;18(4):162-4. PMID: 16729401
Article Published Date : Apr 01, 2006
Study Type : Human Study
Additional Links
Diseases : Coronary Artery Disease, Coronary Stenting
Problem Substances : Anticoagulants, Antiplatelet Drugs, Aspirin , Clopidogrel, Warfarin
[+]

Concomitant use of a proton pump inhibitor and clopidogrel compared with clopidogrel alone was associated with a higher rate of major adverse cardiovascular events within 1 year after coronary stent placement.Aug 01, 2010

Pubmed Data : Pharmacotherapy. 2010 Aug;30(8):787-96. PMID: 20653354
Article Published Date : Aug 01, 2010
Study Type : Human Study
Additional Links
Diseases : Coronary Artery Disease, Coronary Stenting
Additional Keywords : Drug Interaction
Problem Substances : Clopidogrel, Proton-Pump Inhibitors
[+]

Concomitant use of clopidogrel and proton pump inhibitors after hospital discharge for acute coronary syndrome was associated with an increased risk of adverse outcomes than use of clopidogrel without proton pumpin inhibitors. Mar 04, 2009

Pubmed Data : JAMA. 2009 Mar 4;301(9):937-44. PMID: 19258584
Article Published Date : Mar 04, 2009
Study Type : Human Study
Additional Links
Additional Keywords : Drug Interaction
Problem Substances : Clopidogrel
[+]

In this large cohort of older patients with atrial fibrillation, they observed the highest rate of ischemic stroke in the first 30 days after warfarin initiation.Mar 31, 2015

Pubmed Data : Stroke. 2015 Apr ;46(4):1120-2. Epub 2015 Feb 19. PMID: 25700291
Article Published Date : Mar 31, 2015
Study Type : Human Study
Additional Links
Diseases : Brain Ischemia, Stroke
Additional Keywords : Risk Factors
Problem Substances : Warfarin
[+]

Preoperative use of aspirin plus clopidogrel is associated with an increased risk of infection after coronary artery bypass surgery. Apr 27, 2009

Pubmed Data : Arch Intern Med. 2009 Apr 27;169(8):788-96. PMID: 19398691
Article Published Date : Apr 27, 2009
Study Type : Human Study
Additional Links
Diseases : Coronary Artery Disease
Problem Substances : Aspirin , Clopidogrel
[+]

Reduced bone density in patients on long-term warfarin.Jul 01, 2009

Pubmed Data : Int J Rheum Dis. 2009 Jul;12(2):130-5. PMID: 20374330
Article Published Date : Jul 01, 2009
Study Type : Human Study
Additional Links
Diseases : Osteoporosis
Problem Substances : Warfarin
[+]

The effectiveness of anticoagulation therapy for atrial fibrillation is lower in actual practice than in the context of a controlled clinical trial.Sep 12, 1994

Pubmed Data : Arch Intern Med. 1994 Sep 12;154(17):1945-53. PMID: 8074598
Article Published Date : Sep 12, 1994
Study Type : Human Study
Additional Links
Diseases : Atrial Fibrillation
Problem Substances : Warfarin
[+]

The preoperative use of clopidogrel in patients undergoing coronary artery bypass graft surgery showed limited clinical benefits and is associated with increased risk of bleeding and blood transfusion. Sep 01, 2005

Pubmed Data : Ann Thorac Surg. 2005 Sep;80(3):928-33. PMID: 16122457
Article Published Date : Sep 01, 2005
Study Type : Human Study
Additional Links
Diseases : Coronary Artery Disease
Problem Substances : Clopidogrel
[+]

The use of a combination of clopidogrel and aspirin after coronary artery bypass surgery is associated with adverse events. Dec 01, 2001

Pubmed Data : Crit Care Med. 2001 Dec;29(12):2271-5. PMID: 11801823
Article Published Date : Dec 01, 2001
Study Type : Human Study
Additional Links
Diseases : Coronary Artery Disease
Problem Substances : Aspirin , Clopidogrel
[+]

There is an association between anticoagulant medication and massive intraocular hemorrhage in age-related macular degeneration.Jun 01, 2000

Pubmed Data : Graefes Arch Clin Exp Ophthalmol. 2000 Jun;238(6):482-5. PMID: 10943671
Article Published Date : Jun 01, 2000
Study Type : Human Study
Additional Links
Diseases : Intraocular Hemorrhage, Macular Degeneration
Problem Substances : Anticoagulants, Aspirin
[+]

There is an association between anticoagulants and intraocular hemorrhage in patients with neovascular age-related macular degeneration.Nov 01, 2010

Pubmed Data : Retina. 2010 Nov-Dec;30(10):1573-8. PMID: 21060269
Article Published Date : Nov 01, 2010
Study Type : Human Study
Additional Links
Diseases : Intraocular Hemorrhage
Problem Substances : Anticoagulants
[+]

There is high mortality rate associated with aspirin or clopidogrel or both in elderly patients who have head trauma resulting in intracranial hemmorhage. Oct 01, 2008

Pubmed Data : J Trauma. 2008 Oct;65(4):785-8. PMID: 18849791
Article Published Date : Oct 01, 2008
Study Type : Human Study
Additional Links
Diseases : Brain Injury: Traumatic, Intracranial Hemmorhage
Problem Substances : Aspirin , Clopidogrel
[+]

These results implicate several pesticides that are commonly used in agricultural and residential settings with adverse respiratory effects.Jul 05, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Health Perspect. 2016 Jul 6. Epub 2016 Jul 6. PMID: 27384423
Article Published Date : Jul 05, 2016
Study Type : Human Study
Additional Links
Diseases : Allergic Airway Diseases
Additional Keywords : Increased Risk
Problem Substances : Glyphosate, Permethrin, Warfarin
[+]

Traumatic brain injury patients on clopidogrel may have increased long-term disability and fatal consequences when compared with patients who are not on these drugs or on other anticoagulants. Dec 01, 2008

Pubmed Data : J Trauma. 2008 Dec;65(6):1303-8. PMID: 19077618
Article Published Date : Dec 01, 2008
Study Type : Human Study
Additional Links
Diseases : Traumatic Brain Injury
Problem Substances : Clopidogrel
[+]

Warfarin increases mortality of intracerebral hemorrhage (ICH).Sep 28, 2004

Pubmed Data : Neurology. 2004 Sep 28;63(6):1059-64. PMID: 15452298
Article Published Date : Sep 28, 2004
Study Type : Human Study
Additional Links
Diseases : Intracerebral Hemorrhage
Problem Substances : Warfarin
[+]

Warfarin use associates with increased risk for stroke in hemodialysis patients with atrial fibrillation.Oct 01, 2009

Pubmed Data : J Am Soc Nephrol. 2009 Oct;20(10):2223-33. Epub 2009 Aug 27. PMID: 19713308
Article Published Date : Oct 01, 2009
Study Type : Human Study
Additional Links
Diseases : Atrial Fibrillation, Hemodialysis, Stroke
Problem Substances : Warfarin
[+]

Warfarin use beyond two years following diagnosis is associated with poorer prognosis for prostate cancer.May 01, 2010

Pubmed Data : Pharmacoepidemiol Drug Saf. 2010 May;19(5):436-9. PMID: 20437456
Article Published Date : May 01, 2010
Study Type : Human Study
Additional Links
Diseases : Prostate Cancer
Problem Substances : Warfarin
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Warfarin use immediately prior to intracerebral hemorrhage is associated with increased mortality. Mar 01, 2008

Pubmed Data : J Neurol. 2008 Mar;255(3):347-52. Epub 2008 Feb 26. PMID: 18297333
Article Published Date : Mar 01, 2008
Study Type : Human Study
Additional Links
Diseases : Intracerebral Hemorrhage
Problem Substances : Warfarin
[+]

Warfarin use increases the risk of valvular calcification.Dec 01, 2009

Pubmed Data : J Thromb Haemost. 2009 Dec;7(12):2023-7. Epub 2009 Sep 28. PMID: 19793187
Article Published Date : Dec 01, 2009
Study Type : Human Study
Additional Links
Diseases : Aortic Calcification, Arterial Calcification
Problem Substances : Warfarin
[+]

Warfarin, aspirin, or clopidogrel prescription is associated with higher mortality among hemodialysis patients.Apr 01, 2009

Pubmed Data : J Am Soc Nephrol. 2009 Apr;20(4):872-81. Epub 2009 Mar 18. PMID: 19297555
Article Published Date : Apr 01, 2009
Study Type : Human Study
Additional Links
Diseases : Hemodialysis
Problem Substances : Anticoagulants, Antiplatelet Drugs, Aspirin , Clopidogrel, Thrombolytics, Warfarin
[+]

A case of retrobulbar hematoma due to warfarin toxicity has been reported.May 01, 2010

Pubmed Data : West J Emerg Med. 2010 May;11(2):208-10. PMID: 20823976
Article Published Date : May 01, 2010
Study Type : Human: Case Report
Additional Links
Diseases : Hematoma: Retrobulbar
Problem Substances : Warfarin
[+]

Late-onset warfarin-induced skin necrosis has been reported.Mar 01, 1998

Pubmed Data : Am J Hematol. 1998 Mar;57(3):233-7. PMID: 9495376
Article Published Date : Mar 01, 1998
Study Type : Human: Case Report
Additional Links
Diseases : Skin Necrosis
Problem Substances : Warfarin
Adverse Pharmacological Actions : Necrotic
[+]

Purple toes syndrome associated with warfarin therapy has been reported.May 01, 2003

Pubmed Data : Pharmacotherapy. 2003 May;23(5):674-7. PMID: 12741443
Article Published Date : May 01, 2003
Study Type : Human: Case Report
Additional Links
Diseases : Purple Toes Syndrome
Problem Substances : Warfarin
[+]

Warfarin-associated intracapsular hemorrhage causing an acutely painful total hip arthroplasty has been reported.Aug 01, 2000

Pubmed Data : J Arthroplasty. 2000 Aug;15(5):668-70. PMID: 10960007
Article Published Date : Aug 01, 2000
Study Type : Human: Case Report
Additional Links
Diseases : Intracapsular hemorrhage, Total Hip Arthroplasty
Problem Substances : Warfarin
Adverse Pharmacological Actions : Hemorrhagic
[+]

Warfarin-related purple toes syndrome due to cholesterol microembolization has been reported.Jun 01, 1987

Pubmed Data : Am J Med. 1987 Jun;82(6):1233-7. PMID: 3605140
Article Published Date : Jun 01, 1987
Study Type : Human: Case Report
Additional Links
Diseases : Cholesterol Microembolism, Purple Toes Syndrome
Problem Substances : Warfarin
[+]

Dual anti-platelet therapy might pose a hazard when applied to a patient with undiagnosed and untreated malignant cancer prone to undergo vascular mimicry.Apr 02, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2018 Apr 3 ;9(25):17810-17824. Epub 2018 Apr 3. PMID: 29707148
Article Published Date : Apr 02, 2018
Study Type : Animal Study
Additional Links
Diseases : Breast Cancer, Cancer Mortality
Additional Keywords : Increased Risk, Molecular Mimicry
Problem Substances : Aspirin , Clopidogrel
[+]

Warfarin accelerated vascular calcification and worsened cardiac dysfunction in remnant kidney mice.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Chin Med Assoc. 2018 04 ;81(4):324-330. Epub 2018 Feb 13. PMID: 29395943
Article Published Date : Dec 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Diseases : Kidney Failure: Chronic, Vascular Calcification
Additional Keywords : Increased Risk
Problem Substances : Warfarin
[+]

Chronic warfarin therapy is contraindicated in 14% to 44% of patients with atrial fibrillation who are at risk for stroke.Nov 26, 2010

Pubmed Data : Int J Cardiol. 2010 Nov 26. Epub 2010 Nov 26. PMID: 21112648
Article Published Date : Nov 26, 2010
Study Type : Review
Additional Links
Diseases : Atrial Fibrillation
Problem Substances : Warfarin
[+]

Genetic differents in patients being administered warfarin may account for increased frequency of bleeding, and prolongation of hospitalization in patients with variant CYP2C9 alleles. Feb 01, 2001

Pubmed Data : Pharmacotherapy. 2001 Feb;21(2):235-42. PMID: 11213860
Article Published Date : Feb 01, 2001
Study Type : Review
Additional Links
Additional Keywords : Genetic Differences
Problem Substances : Warfarin
[+]

The combination of clopidogrel and aspirin may be harmful, compared with aspirin alone.Nov 01, 2007

Pubmed Data : Curr Treat Options Neurol. 2007 Nov;9(6):442-50. PMID: 18173943
Article Published Date : Nov 01, 2007
Study Type : Commentary
Additional Links
Diseases : Stroke: Prevention
Additional Keywords : Drug Interaction
Problem Substances : Aspirin , Clopidogrel
[+]

Warfarin and lovastatin exhibit embryotoxic potential.Aug 01, 2010

Pubmed Data : Reprod Toxicol. 2010 Aug;30(1):121-30. Epub 2010 May 20. PMID: 20493250
Article Published Date : Aug 01, 2010
Study Type : In Vitro Study
Additional Links
Diseases : Prenatal Chemical Exposures
Problem Substances : Lovastatin, Warfarin
Adverse Pharmacological Actions : Embryotoxic, Teratogenic
[+]

Warfarin induced skin necrosis has been reported as a rare but important complication. Mar 01, 2000

Pubmed Data : Br J Surg. 2000 Mar;87(3):266-72. PMID: 10718793
Article Published Date : Mar 01, 2000
Study Type : Commentary
Additional Links
Diseases : Skin Necrosis
Problem Substances : Warfarin
Adverse Pharmacological Actions : Necrotic
[+]

Warfarin metabolites may inhibt the metabolism of S-warfarin which could suppress feedback inhibition and cause adverse effects.May 17, 2010

Pubmed Data : Chem Res Toxicol. 2010 May 17;23(5):939-45. PMID: 20429590
Article Published Date : May 17, 2010
Study Type : In Vitro Study
Additional Links
Problem Substances : Warfarin
[+]

Warfarin withdrawal may result in a rebound (hyper-coagulant) effect. Apr 01, 1996

Pubmed Data : Clin Pharmacokinet. 1996 Apr;30(4):300-13. PMID: 8983860
Article Published Date : Apr 01, 1996
Study Type : Review
Additional Links
Diseases : Thrombosis
Additional Keywords : Drug Rebound Effect
Problem Substances : Warfarin

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