Arsenic

Name	AC	CK
Arsenic Poisoning	51	132
Autism Spectrum Disorders	5	50
Childhood Cognitive Disorders	3	40
Intelligence Quotient (IQ): Low/Impaired	3	40
Heavy Metal Toxicity	5	24
Prenatal Chemical Exposures	2	22
Chemically-Induced Liver Damage	11	20
Childhood Chemical Exposures	2	20
Oxidative Stress	10	17
DNA damage	4	14
Cardiovascular Diseases	2	12
Dysbiosis	2	12
Basal Cell Carcinoma	1	10
Bladder Cancer	1	10
Cadmium Poisoning	1	10
Children: Impaired Growth	1	10
Copper Toxicity	1	10
Diabetes Mellitus: Type 2	1	10
Folic Acid/Folate Deficiency	1	10
Infertility: Female	1	10
Iron Poisoning	1	10
Kidney Damage: Chemically-Induced	5	10
Lead Poisoning	1	10
Mercury Poisoning	1	10
Pneumonia	1	10
Skin Cancer	1	10
Sleep Disorders	1	10
Spina Bifida	1	10
Squamous cell carcinoma	1	10
Water Contamination	1	10
Chemotherapy-Induced Toxicity: Arsenic Trioxide	3	5
Infertility: Male	1	4
Inflammation	2	4
Sperm Quality: Low	1	4
Leukemia: Acute promyelocytic leukemia	2	3
Lung Cancer	3	3
Mitochondrial Dysfunction	2	3
Anxiety	1	2
Birth Defects	1	2
Bisphenol Toxicity	1	2
Chronic Kidney Disease of Unknown Etiology (CKDu)	1	2
Depression	1	2
Glyphosate Toxicity	1	2
Lipid Peroxidation	1	2
Liver Damage	1	2
Lung Injury: Acute	1	2
Neurodegenerative Diseases	1	2
Pesticide Toxicity	1	2
Benzo[a]pyrene-induced Toxicity	1	1
Brain Cancer	1	1
Breast Cancer	1	1
Cancers: Estrogen Responsive	1	1
Cardiotoxicity: Chemotherapy-Induced	1	1
Estrogen Dominance	1	1
Learning disorders	1	1
Memory Disorders	1	1

Name	AC	CK
Neurotoxic	4	50
Cardiotoxic	2	4
Inflammatory	1	2
Interleukin-6 up-regulation	1	2
Interleukin-8 up-regulation	1	2
MCP-1 (CCL2) up-regulation	1	2
P-selectin upregulation	1	2
Teratogenic	1	2
Vascular Cell Adhesion Molecule-1 (VCAM-1) Up-Regulation	1	2
Estrogenic	1	1
Genotoxic	1	1

Children with autism spectrum disorder had significantly higher levels of mercury and arsenic.May 07, 2017

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Pubmed Data : Biol Trace Elem Res. 2017 May 8. Epub 2017 May 8. PMID: 28480499

Article Published Date : May 07, 2017

Study Type : Human Study

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Diseases : Autism Spectrum Disorders

Problem Substances : Arsenic, Mercury

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Pubmed Data : Environ Health. 2015 ;14(1):34. Epub 2015 Apr 10. PMID: 25885259

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Pubmed Data : Biol Trace Elem Res. 2022 Dec ;200(12):4967-4976. Epub 2022 Jan 22. PMID: 35064870

Article Published Date : Nov 30, 2022

Study Type : Human Study

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Substances : Ginkgo biloba

Diseases : Arsenic Poisoning

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-17 downregulation

Additional Keywords : Plant Extracts

Problem Substances : Arsenic

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Heavy metal accumulation and associated biochemical alterations are found in Autistic Spectrum Disorder.Jul 14, 2011

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Pubmed Data : Biol Trace Elem Res. 2011 Jul 14. Epub 2011 Jul 14. PMID: 21755304

Article Published Date : Jul 14, 2011

Study Type : Human Study

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Diseases : Arsenic Poisoning, Autism Spectrum Disorders, Copper Toxicity, Heavy Metal Toxicity, Iron Poisoning, Mercury Poisoning

Additional Keywords : Diseases that are Linked

Problem Substances : Arsenic, Industrial Copper (inorganic), Industrial Iron, Mercury

Adverse Pharmacological Actions : Neurotoxic

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Independent and combined associations of urinary arsenic exposure and serum sex steroid hormones among 6-19-year old children and adolescents.Mar 09, 2023

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Pubmed Data : Sci Total Environ. 2023 Mar 10 ;863:160883. Epub 2022 Dec 13. PMID: 36526194

Article Published Date : Mar 09, 2023

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Selenium attenuates the association of co-exposure to arsenic, cadmium, and lead with cognitive function.Dec 21, 2022

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Pubmed Data : Environ Sci Pollut Res Int. 2022 Dec 22. Epub 2022 Dec 22. PMID: 36547832

Article Published Date : Dec 21, 2022

Study Type : Human Study

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Substances : Selenium

Diseases : Arsenic Poisoning, Cadmium Poisoning , Lead Poisoning

Pharmacological Actions : Neuroprotective Agents

Problem Substances : Arsenic, Cadmium, Lead

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These findings support an association between low-to-moderate levels of arsenic in drinking water and bladder cancer risk.Aug 31, 2016

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Pubmed Data : J Natl Cancer Inst. 2016 Sep ;108(9). Epub 2016 May 2. PMID: 27140955

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Pubmed Data : Environ Sci Pollut Res Int. 2016 Nov 17. Epub 2016 Nov 17. PMID: 27858272

Article Published Date : Nov 16, 2016

Study Type : Human Study

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Diseases : Sleep Disorders

Additional Keywords : Risk Factors

Problem Substances : Aromatic hydrocarbons, Arsenic, Heavy Metals, Pesticides, Phthalates

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Protective effects of crocetin on arsenic trioxide-induced oxidative stress.Oct 31, 2021

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Pubmed Data : Nagoya J Med Sci. 2015 Feb ;77(1-2):145-53. PMID: 25797979

Article Published Date : Jan 31, 2015

Study Type : Animal Study

Additional Links

Substances : Amla Fruit

Diseases : Arsenic Poisoning

Pharmacological Actions : Antioxidants, Hepatoprotective, Renoprotective

Additional Keywords : Plant Extracts

Problem Substances : Arsenite

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An ethanol leaf extract of A. conyzoides possess strong potentials to protect against toxicities induced by sodium arsenite.Feb 29, 2016

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Pubmed Data : Food Chem Toxicol. 2016 Aug ;94:112-27. Epub 2016 May 24. PMID: 27234133

Article Published Date : Jul 31, 2016

Study Type : Animal Study

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Substances : Ginkgo biloba, Red Clover

Diseases : Neurodegenerative Diseases

Pharmacological Actions : Neuroprotective Agents, Prophylactic Agents

Additional Keywords : Natural Substance Synergy

Problem Substances : Arsenite

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Grape seed and skin extract has the potential to protect against arsenic trioxide-induced cardiotoxicity.Jul 28, 2015

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Pubmed Data : Can J Physiol Pharmacol. 2015 Jul 29:1-9. Epub 2015 Jul 29. PMID: 26560635

Problem Substances : Arsenic

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Moringa oleifera may be useful in reducing the effects of arsenic-induced toxicity.Apr 30, 2014

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Pubmed Data : Asian Pac J Trop Biomed. 2014 May ;4(Suppl 1):S353-8. PMID: 25183111

Article Published Date : Apr 30, 2014

Study Type : Animal Study

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Substances : Moringa oleifera

Diseases : Arsenic Poisoning

Pharmacological Actions : Cytoprotective

Problem Substances : Arsenic

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Neuroprotective mechanisms of selenium against arsenic-induced behavioral impairments in rats.Oct 30, 2019

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Pubmed Data : Neurotoxicology. 2019 Oct 31 ;76:99-110. Epub 2019 Oct 31. PMID: 31678059

Article Published Date : Oct 30, 2019

Study Type : Animal Study

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Substances : Selenium

Diseases : Arsenic Poisoning

Pharmacological Actions : Acetylcholinesterase Inhibitor, Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents

Problem Substances : Arsenic

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Organic brown rice syrup (OBRS) may have high levels of arsenic. Feb 16, 2012

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Pubmed Data : Environ Health Perspect. 2012 Feb 16. Epub 2012 Feb 16. PMID: 22336149

Article Published Date : Feb 16, 2012

Study Type : Environmental

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Problem Substances : Arsenic

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Pomegranate fruit extract reversed arsenic-induced hepatotoxicity and apoptosis.Sep 05, 2016

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Pubmed Data : J Nutr Biochem. 2016 Sep 6 ;38:25-40. Epub 2016 Aug 6. PMID: 27723467

Article Published Date : Sep 05, 2016

Study Type : Animal Study

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Substances : Pomegranate

Diseases : Chemically-Induced Liver Damage

Pharmacological Actions : Anti-Apoptotic, Hepatoprotective

Problem Substances : Arsenic

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Potency of spirulina on arsenic-induced lipid peroxidation.May 31, 2021

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Pubmed Data : Appl Biochem Biotechnol. 2018 Mar 2. Epub 2018 Mar 2. PMID: 29497947

Article Published Date : Mar 01, 2018

Study Type : Animal Study

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Substances : Hydroxytyrosol

Diseases : Arsenic Poisoning

Pharmacological Actions : Antioxidants, Neuroprotective Agents

Problem Substances : Arsenic

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Protective effects of 6-gingerol on cardiotoxicity induced by arsenic trioxide.Dec 31, 2021

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Pubmed Data : Biometals. 2020 Oct 7. Epub 2020 Oct 7. PMID: 33026605

Article Published Date : Oct 06, 2020

Study Type : Animal Study

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Substances : Guduchi

Diseases : Chemically-Induced Liver Damage, Kidney Damage: Chemically-Induced

Pharmacological Actions : Hepatoprotective, Renoprotective

Problem Substances : Arsenic

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The present findings showed that kolaviron might be a potent product for mitigating NaAsO2 toxicity in the gastrointestinal tract.Jun 30, 2015

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Pubmed Data : Pharmacognosy Res. 2015 Jul-Sep;7(3):268-76. PMID: 26130939

Article Published Date : Jun 30, 2015

Study Type : Animal Study

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Substances : Flavonoids, Garcinia kola

Diseases : Arsenic Poisoning

Pharmacological Actions : Anti-Inflammatory Agents, Gastroprotective

Problem Substances : Arsenic

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Thymoquinone plays a protective role against arsenic-induced toxicity in kidney and may potentially be used as a remedial agent.Oct 28, 2015

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Pubmed Data : Ren Fail. 2015 Oct 29:1-7. Epub 2015 Oct 29. PMID: 26513487

Article Published Date : Oct 28, 2015

Study Type : Animal Study

Additional Links

Substances : Thymoquinone

Diseases : Kidney Damage: Chemically-Induced, Oxidative Stress

Pharmacological Actions : Anti-Apoptotic, Renoprotective

Problem Substances : Arsenic

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Thymoquinone supplementation mitigates arsenic-induced cytotoxic and genotoxic alterations.Sep 12, 2022

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Pubmed Data : J Trace Elem Med Biol. 2022 Sep 13 ;74:127067. Epub 2022 Sep 13. PMID: 36155422

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Pubmed Data : Naunyn Schmiedebergs Arch Pharmacol. 2020 08 ;393(8):1365-1372. Epub 2020 Feb 6. PMID: 32025748

Article Published Date : Dec 31, 2019

Study Type : In Vitro Study

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Substances : Aloe Vera

Diseases : Oxidative Stress

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cardioprotective

Problem Substances : Arsenic Trioxide

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Alpha-mangostin protects PC12 cells against neurotoxicity induced by cadmium and arsenic.Nov 28, 2022

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Pubmed Data : Biol Trace Elem Res. 2022 Nov 29. Epub 2022 Nov 29. PMID: 36445559

Article Published Date : Nov 28, 2022

Study Type : In Vitro Study

Additional Links

Substances : Mangosteen

Diseases : Arsenic Poisoning, Cadmium Poisoning

Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents

Problem Substances : Arsenic, Cadmium

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Pubmed Data : Oncotarget. 2017 Sep 12 ;8(39):65302-65312. Epub 2017 Jun 21. PMID: 29029432

Article Published Date : Sep 11, 2017

Study Type : In Vitro Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Arsenic Poisoning, Chemically-Induced Liver Damage

Pharmacological Actions : Antioxidants, Hepatoprotective, Nrf2 activation

Problem Substances : Arsenic

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Ellagic acid treatment exerts a significant protective effect on sodium arsenic-induced cardio and hematotoxicity.Jan 29, 2018

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Pubmed Data : Cardiovasc Toxicol. 2018 Jan 30. Epub 2018 Jan 30. PMID: 29383632

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Pubmed Data : Physiol Mol Biol Plants. 2020 Jan ;26(1):63-81. Epub 2019 Nov 27. PMID: 32158121

Article Published Date : Dec 31, 2019

Study Type : Plant Study

Additional Links

Substances : Holy Basil, Neem, Rice

Pharmacological Actions : Antioxidants

Problem Substances : Arsenic

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Nickel, chromate, and arsenite may contribute to lung cancer and other adverse health effects through altering the expression of genes. Apr 01, 2009

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Pubmed Data : Toxicol Appl Pharmacol. 2009 Apr 1;236(1):78-84. Epub 2009 Jan 27. PMID: 19371620

Article Published Date : Apr 01, 2009

Study Type : In Vitro Study

Additional Links

Diseases : Lung Cancer

Problem Substances : Arsenite, Chromate

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Pectic polysaccharides of Momordica charantia in combination with curcumin had liver protective effects.Aug 31, 2017

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Pubmed Data : Biochem Biophys Rep. 2017 Sep ;11:64-71. Epub 2017 Jun 23. PMID: 28955769

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Pubmed Data : Front Pharmacol. 2019 ;10:497. Epub 2019 May 8. PMID: 31139082

Article Published Date : Dec 31, 2018

Study Type : In Vitro Study

Additional Links

Substances : Pterostilbene

Diseases : Arsenic Poisoning

Pharmacological Actions : Antioxidants, Nrf2 activation

Problem Substances : Arsenic

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Rosa roxburghii could be an effective prevention and control strategies for arsenic poisoning.Dec 31, 2021

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The Following are Sub-Topics of Arsenic

View the Evidence: 141 Abstracts with Arsenic Research

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Children who live in an arsenicosis area or a slight arsenicosis area have lower IQ than those who live in a non-arsenicosis area.Jan 01, 2009

Alcohol consumption moderated the association between levels of high blood lead or total urinary arsenic and bone loss.Dec 31, 2020

Autism spectrum disorder prevalence and proximity to industrial facilities releasing arsenic, lead or mercury.Nov 30, 2015

Autism spectrum disorders in relation to distribution of hazardous air pollutants in the san francisco bay area.Aug 31, 2006

Children with autism spectrum disorder had significantly higher levels of mercury and arsenic.May 07, 2017

Children's growth and intelligence can be adversely affected by fluoride and arsenic exposure in drinking water.Apr 01, 2007

Curcumin reduces arsenic-induced DNA damage in human subjects. Mar 01, 2011

Dietary flavonoids improve urinary arsenic elimination among Mexican women.Jun 30, 2018

Docosahexaenoic acid effect on prenatal exposure to arsenic and atopic dermatitis in Mexican preschoolers.Sep 07, 2022

Drinking water arsenic was associated with increased risk of cardiovascular disease among residents exposed to moderate levels of arsenic.Apr 11, 2015

Environmental arsenic exposure reduces the effectiveness of folic acid supplementation in preventing myelomeningocele.Dec 31, 2014

Exposure to fluoride and arsenic in drinking water is associated with decreased intelligence in children.Jan 01, 2007

Genetic variation in NOTCH2 increased the susceptibility to T2DM among people exposed to inorganic arsenic.Dec 31, 2012

Ginkgo biloba extract attenuates the disruption of pro- and anti-inflammatory balance of peripheral blood in arsenism patients.Nov 30, 2022

Heavy metal accumulation and associated biochemical alterations are found in Autistic Spectrum Disorder.Jul 14, 2011

Independent and combined associations of urinary arsenic exposure and serum sex steroid hormones among 6-19-year old children and adolescents.Mar 09, 2023

Inorganic arsenic contents in rice-based infant foods from Spain, UK, China and USA.Mar 31, 2012

Low level arsenic contamination in residential drinking water sources may further impair fertility among women.Jan 02, 2017

Low to moderate arsenic exposure may be a risk factor for pneumonia in children under 5 years of age. Dec 31, 2014

Physical training produces a decrease in erythrocyte concentrations of cadmium and lead.Jul 28, 2019

Potential value and mechanism of Rosa roxburghii tratt juice on pro-inflammatory responses in peripheral blood of patients with arsenic poisoning.Dec 31, 2021

Selenium attenuates the association of co-exposure to arsenic, cadmium, and lead with cognitive function.Dec 21, 2022

These findings support an association between low-to-moderate levels of arsenic in drinking water and bladder cancer risk.Aug 31, 2016

These results indicate significant alterations in the trace element and gut microbiota profiles of Chinese children with autism spectrum disorder.Mar 31, 2019

This population based study that shows the relationship between arsenic intoxication and non-melanoma skin cancers.Aug 17, 2015

Urinary arsenic, pesticides, heavy metals, phthalates, polyaromatic hydrocarbons, and polyfluoroalkyl compounds are associated with sleep troubles in adults.Nov 16, 2016

Protective effects of crocetin on arsenic trioxide-induced oxidative stress.Oct 31, 2021

Administration of tetrahydrocurcumin exhibited significant reversal of arsenic induced toxicity in hepatic tissue.Jun 24, 2015

Allicin provides protection against arsenic trioxide induced liver injury. Feb 28, 2017

Alpha-lipoic acid could prevent from mitochondria dysfunction.Apr 16, 2021

Ameliorative effects and mechanism of crocetin in arsenic trioxide‑induced cardiotoxicity.Nov 30, 2020

Amla fruit provides protection against arsenics induced inflammation and immunotoxicity.Dec 31, 2014

Amla leaf extract might have therapeutic application for protecting against arsenic-mediated toxicity.Jan 31, 2015

An ethanol leaf extract of A. conyzoides possess strong potentials to protect against toxicities induced by sodium arsenite.Feb 29, 2016

Aqueous C. papaya roots preparations might have therapeutic potential as a supplement that can be applied in arsenic poisoning.Mar 31, 2018

Aquoeus extracts of Daucus carota protected the postnatal developing cerebellum against arsenic-induced oxidative stress.Dec 30, 2021

Arsenic exposure alters the gut microbiome at the abundance level and also substantially disturbs its metabolic profiles at the function level.Feb 28, 2014

Arsenic trioxide alters the differentiation of mouse embryonic stem cell into cardiomyocytes.Dec 31, 2014

Arsenite is more harmful than arsenate to sperm quality and male fertility.Dec 31, 2017

Based on activation of p62-Keap1-Nrf2 pathway, hesperidin protects arsenic-trioxide-induced cardiotoxicity.Dec 31, 2020

Biochanin A ameliorates arsenic-induced hepato- and hematotoxicity in rats.Jan 08, 2016

Carnosic acid attenuates arsenic-induced hepatotoxicity.Dec 31, 2017

Chlorogenic acid could be a potential therapeutic to minimize sodium arsenite-induced hepatic injury.Jan 31, 2020

Chrysin attenuates sodium arsenite-induced nephrotoxicity in rats by suppressing oxidative stress and inflammation.Sep 26, 2021

Co-administration of vitamin C and E significantly prevented arsenic-induced alterations in this study. Oct 31, 2016

Crocetin attenuates the oxidative stress, inflammation and apoptosis in arsenic trioxide-induced nephrotoxic rats.Sep 08, 2020

Curcumin compensated the adverse effects of sodium arsenite on kidney tissue, lipid peroxidation and total antioxidant capacity of serum.Nov 27, 2016

Curcumin functions as an anti-inflammatory and antioxidant agent on arsenic-induced hepatic and kidney injury.Jul 16, 2021

EGCG could attenuate Sodium arsenite-induced cardiotoxicity.May 07, 2016

EGCG inhibits arsenic-induced inflammation and apoptosis through suppression of oxidative stress in mice.Apr 02, 2017

EGCG may be useful for reducing hepatotoxicity associated with oxidative stressJun 20, 2017

Ellagic acid can effectively protect brain tissue against sodium arsenate-induced neurotoxicity.Mar 31, 2018

Epigallocatechin gallate attenuates arsenic induced genotoxicity via regulation of oxidative stress.Jul 25, 2019

Eriodictyol attenuates arsenic trioxide-induced liver injury by activation of Nrf2.Sep 14, 2017

Feather meal products represent a previously unrecognized source of arsenic in the food system, and may pose additional risks to humans as a result of its use as an organic fertilizer and when animal waste is managed.Feb 15, 2012

Ferulic acid attenuates arsenic induced cardiotoxicity.Oct 03, 2019

Findings suggest that agrochemicals especially phosphate fertilizers are a major source of inorganic arsenic in CKDu endemic areas in Sri Lanka.Dec 31, 2014

Fisetin attenuates arsenic-induced hepatic damage.Dec 31, 2021

Fluoride and arsenic exhibit cardiotoxic properties related to their pro-inflammatory effect.Mar 16, 2012

Gallic acid ameliorates sodium arsenite-induced renal and hepatic toxicity.Mar 24, 2019

Ginkgo biloba and red clover in combination was more effective as protective agents compared to each one of them alone.Jul 31, 2016

Grape seed and skin extract has the potential to protect against arsenic trioxide-induced cardiotoxicity.Jul 28, 2015

Grape seed proanthocyanidin extract alleviates arsenic-induced lung damage through NF-κB signaling.Feb 28, 2019

Grape seed procyanidin extract reduces arsenic-induced renal inflammatory injury in male mice.Jun 30, 2017

Green tea could protect against arsenic induced neurotoxicity. Jan 31, 2017

Hesperidin has a protective effect on sodium arsenite-induced nephrotoxicity and hepatotoxicity.Jul 30, 2018

Imidacloprid combined with arsenic possessed synergistic toxicity on rat livers. Sep 30, 2018

Immunomodulatory effects of nanocurcumin in arsenic-exposed rats.Aug 31, 2013

Joint toxicity of arsenic, copper and glyphosate on behaviour, reproduction and heat Shock protein response in Caenorhabditis elegans.Mar 31, 2017

Kolaviron attenuated arsenic acid induced-cardiorenal dysfunction.Jun 30, 2018

Lentinan alleviates arsenic-induced hepatotoxicity in mice.Jan 21, 2022

Low levels of selenium, fluoride and arsenic are toxic to rat embryos.Mar 30, 1999

Arsenic

View the Evidence:
141 Abstracts with Arsenic Research