Benzene

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31 Diseases Researched for Benzene

Name	AC	CK
Leukemia	6	34
Benzene Toxicity	9	32
Leukemia: Acute myelogenous leukemia (AML)	4	31
DNA damage	6	25
Chronic Myeloid Leukemia	3	21
Acute Myeloid Leukemia	1	10
Air Pollution Linked Toxicity	1	10
All-Cause Mortality	1	10
Atopic Disease	1	10
Breast Cancer	1	10
Cancer Mortality	1	10
Cardiac Mortality	1	10
Endothelial Dysfunction	1	10
Hypertension	1	10
Infertility: Male	1	10
Leukemia: Monocytic	1	10
Lymphoma	1	10
Multiple Myeloma	1	10
Myelodysplastic Syndrome	1	10
Prenatal Chemical Exposures	1	10
Sick Building Syndrome	1	10
Smoking	1	10
Sperm Quality: Low	1	10
Oxidative Stress	2	3
Chemically-Induced Liver Damage	1	2
Dysbiosis	1	2
Leucopenia	1	2
Leukopenia	1	2
Testicular Injury: Chemical/Metal Induced	1	2
Cancers: All	1	1
Hematologic Diseases	1	1

3 Adverse Pharmacological Actions Researched for Benzene

Name	AC	CK
Carcinogen	1	10
Carcinogenic	1	10
Hypertensive	1	10

Research Articles 36
Cumulative Knowledge Score 58
Overall Research Rating GOOD

View the Evidence:
36 Abstracts with Benzene Research

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[+]

A broccoli seed and sprout extract significantly upregulated detoxification of the tobacco carcinogens benzene, acrolein, and crotonaldehyde.Apr 23, 2022

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Cancers (Basel). 2022 Apr 24 ;14(9). Epub 2022 Apr 24. PMID: 35565256

Article Published Date : Apr 23, 2022

Study Type : Human Study

Additional Links

Substances : Broccoli Sprouts

Diseases : Benzene Toxicity, Smoking

Pharmacological Actions : Detoxifier

Problem Substances : Benzene

[+]

Benzene and Aspergillus exposures are associated with sick building syndrome.Sep 15, 2009

Click here to read the entire abstract

Pubmed Data : Sci Total Environ. 2009 Sep 15;407(19):5223-8. Epub 2009 Jul 15. PMID: 19608217

Article Published Date : Sep 15, 2009

Study Type : Human Study

Additional Links

Diseases : Sick Building Syndrome

Problem Substances : Aspergillus, Benzene

[+]

Benzene exposure at below 1 part per million (1 ppm) causes hematotoxicity in exposed workers.Mar 19, 2010

Click here to read the entire abstract

Pubmed Data : Chem Biol Interact. 2010 Mar 19;184(1-2):86-93. Epub 2009 Dec 21. PMID: 20026094

Article Published Date : Mar 19, 2010

Study Type : Human Study

Additional Links

Diseases : DNA damage

Problem Substances : Benzene

[+]

Benzene exposure in parts per billion has been shown to adversely effect DNA in a manner consisent with increased risk for lymphoma and leukemia.May 30, 2005

Click here to read the entire abstract

Pubmed Data : Chem Biol Interact. 2005 May 30;153-154:75-83. Epub 2005 Apr 1. PMID: 15935802

Article Published Date : May 30, 2005

Study Type : Human Study

Additional Links

Diseases : DNA damage, Leukemia, Lymphoma

Problem Substances : Benzene

[+]

Benzene exposure is associated with hypertension, possibly due to disturbance of nitric oxide process.Jul 01, 2007

Click here to read the entire abstract

Pubmed Data : Cardiovasc J Afr. 2007 Jul-Aug;18(4):264-5. PMID: 17940673

Article Published Date : Jul 01, 2007

Study Type : Human Study

Additional Links

Diseases : Endothelial Dysfunction, Hypertension

Problem Substances : Benzene

Adverse Pharmacological Actions : Hypertensive

[+]

Benzene exposure is associated with leukemia-associated changes in the peripheral blood lymphocytes of workers.Jan 07, 2011

Click here to read the entire abstract

Pubmed Data : Carcinogenesis. 2011 Jan 7. Epub 2011 Jan 7. PMID: 21216845

Article Published Date : Jan 07, 2011

Study Type : Human Study

Additional Links

Diseases : Leukemia: Acute myelogenous leukemia (AML)

Problem Substances : Benzene

Adverse Pharmacological Actions : Carcinogen

[+]

Benzene exposure near the US permissible limit is associated wtih sperm aneuploidy (chromosomal abnormality).Jan 06, 2010

Click here to read the entire abstract

Pubmed Data : Environ Health Perspect. 2010 Jan 6. Epub 2010 Jan 6. PMID: 20418200

Article Published Date : Jan 06, 2010

Study Type : Human Study

Additional Links

Diseases : Infertility: Male, Sperm Quality: Low

Problem Substances : Benzene

[+]

Crude oil exposure has been linked to acute myelogenous leukemia and multiple myeloma, in part due to benzene.Feb 01, 2008

Click here to read the entire abstract

Pubmed Data : Cancer Causes Control. 2008 Feb;19(1):13-23. Epub 2007 Sep 29. PMID: 17906934

Article Published Date : Feb 01, 2008

Study Type : Human Study

Additional Links

Diseases : Leukemia: Acute myelogenous leukemia (AML) , Multiple Myeloma

Problem Substances : Benzene, Crude Oil/Petroleum

[+]

Electromagnetic fields have a greater influence on women with a predisposition to allergic responses who are exposed to toxic traffic emissions than women without predispostions to allergic responses.Jul 01, 2000

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Ind Health. 2000 Jul ;38(3):294-300. PMID: 10943077

Article Published Date : Jul 01, 2000

Study Type : Human Study

Additional Links

Diseases : Atopic Disease

Additional Keywords : EMF

Anti Therapeutic Actions : Electromagnetic Field Harms, Electromagnetic Radiation

Problem Substances : Benzene, Lead

[+]

Exposure to toxic compounds from an oil spill is correlated with an increased risk of health effects among pregnant women. Mar 01, 2009

Click here to read the entire abstract

Pubmed Data : J Prev Med Public Health. 2009 Mar;42(2):96-103. PMID: 19349738

Article Published Date : Mar 01, 2009

Study Type : Human Study

Additional Links

Diseases : Prenatal Chemical Exposures

Problem Substances : Benzene, Crude Oil/Petroleum, Ethylbenzene, Toluene, Xylene

[+]

Exposure to various chemicals is associated with increased risk for myelodysplastic syndrome according to the WHO.Feb 01, 2011

Click here to read the entire abstract

Pubmed Data : Am J Hematol. 2011 Feb;86(2):163-169. PMID: 21264898

Article Published Date : Feb 01, 2011

Study Type : Human Study

Additional Links

Diseases : Myelodysplastic Syndrome

Problem Substances : Benzene, Crude Oil/Petroleum, Herbicide, Pesticides, Tobacco: Smoking

[+]

Hazardous air pollutants and breast cancer risk in California teachers: a cohort study.Jan 29, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Environ Health. 2015 Jan 30 ;14(1):14. Epub 2015 Jan 30. PMID: 25636809

Article Published Date : Jan 29, 2015

Study Type : Human Study

Additional Links

Diseases : Breast Cancer

Problem Substances : Acrylamide , Benzene, Vinyl chloride

Adverse Pharmacological Actions : Carcinogenic

[+]

Long-term exposure to low-level ambient benzene significantly increases mortality risk in the general population.Dec 20, 2023

Click here to read the entire abstract

Pubmed Data : Am J Respir Crit Care Med. 2023 Dec 21. Epub 2023 Dec 21. PMID: 38128545

Article Published Date : Dec 20, 2023

Study Type : Human Study

Additional Links

Diseases : All-Cause Mortality, Cancer Mortality, Cardiac Mortality

Problem Substances : Benzene

[+]

Myeloid leukemia was associated with benzene, a nonspecific group of solvents, occupational pesticides, and working with or near powerlines.Nov 01, 2009

Click here to read the entire abstract

Pubmed Data : Ann Hematol. 2009 Nov ;88(11):1079-88. Epub 2009 Mar 18. PMID: 19294385

Article Published Date : Nov 01, 2009

Study Type : Human Study

Additional Links

Diseases : Acute Myeloid Leukemia, Chronic Myeloid Leukemia, Leukemia

Additional Keywords : EMF, RF-EMF and Cancers

Anti Therapeutic Actions : Electromagnetic Field Harms, Electromagnetic Radiation, Microwave Radiation

Problem Substances : Benzene, Pesticides

[+]

Offshore workers have a higher risk of acute myelogenous leukemia, probably due to benzene exposure.Oct 21, 2004

Click here to read the entire abstract

Pubmed Data : Tidsskr Nor Laegeforen. 2004 Oct 21;124(20):2627-9. PMID: 15534638

Article Published Date : Oct 21, 2004

Study Type : Human Study

Additional Links

Diseases : Leukemia: Acute myelogenous leukemia (AML)

Problem Substances : Benzene, Crude Oil/Petroleum

[+]

Pathological protein adducts are associated with benzene and benzene metabolite exposures. May 30, 2005

Click here to read the entire abstract

Pubmed Data : Chem Biol Interact. 2005 May 30;153-154:103-9. Epub 2005 Apr 9. PMID: 15935805

Article Published Date : May 30, 2005

Study Type : Human Study

Additional Links

Problem Substances : Benzene, Benzene Metabolites

[+]

Sulforaphane detoxifies benzene, an air pollutant, in a dose-dependent manner and may attentuate attenuate associated long-term health risks of air pollution. Jul 03, 2019

Click here to read the entire abstract

Pubmed Data : Am J Clin Nutr. 2019 Jul 3. Epub 2019 Jul 3. PMID: 31268126

Article Published Date : Jul 03, 2019

Study Type : Human Study

Additional Links

Substances : Broccoli Sprouts, Sulforaphane

Diseases : Air Pollution Linked Toxicity, Benzene Toxicity

Pharmacological Actions : Antioxidant Effects, Detoxifier

Additional Keywords : Airborne Pollution, Broccoli, Broccoli Sprouts, Cruciferous Vegetables, Dose Response, Environmental Pollutant, Environmental Pollution

Problem Substances : Airborne Pollution, Benzene

[+]

Workers exposed to petroleum products may have increased risk for certain leukemias, in part due to benzene exposure.Mar 01, 1997

Click here to read the entire abstract

Pubmed Data : Occup Environ Med. 1997 Mar;54(3):152-66. PMID: 9155776

Article Published Date : Mar 01, 1997

Study Type : Human Study

Additional Links

Diseases : Chronic Myeloid Leukemia, Leukemia, Leukemia: Monocytic

Problem Substances : Benzene, Crude Oil/Petroleum

[+]

An extract of moringa oleifera demonstrated chemopreventive and anti-leukemic activities as much as the standard anti-leukemic drug cyclophosphamide.Dec 31, 2013

Click here to read the entire abstract

Pubmed Data : Curr Pharm Biotechnol. 2014 ;15(6):563-8. PMID: 25051949

Article Published Date : Dec 31, 2013

Study Type : Animal Study

Additional Links

Substances : Moringa oleifera

Diseases : Leukemia

Pharmacological Actions : Chemopreventive

Additional Keywords : Natural Substances Versus Drugs, Plant Extracts

Problem Substances : Benzene

[+]

Antioxidant mechanism of diallyl sulfide in inhibiting leucopenia in peripheral blood induced by benzene.Oct 19, 2019

Click here to read the entire abstract

Pubmed Data : Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2019 Oct 20 ;37(10):737-745. PMID: 31726503

Article Published Date : Oct 19, 2019

Study Type : Animal Study

Additional Links

Substances : Diallyl sulfide

Diseases : Benzene Toxicity, Leucopenia, Oxidative Stress

Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation, Superoxide Dismutase Up-regulation

Problem Substances : Benzene

[+]

Benzene exposure induces gut microbiota dysbiosis and metabolic disorder in mice.Feb 24, 2020

Click here to read the entire abstract

Pubmed Data : Sci Total Environ. 2020 Feb 25 ;705:135879. Epub 2019 Dec 2. PMID: 31972927

Article Published Date : Feb 24, 2020

Study Type : Animal Study

Additional Links

Diseases : Benzene Toxicity, Dysbiosis

Additional Keywords : Risk Factors

Problem Substances : Benzene

[+]

Pre-treatment with beta carotene gives protection against nephrotoxicity induced by bromobenzene.Aug 12, 2019

Click here to read the entire abstract

Pubmed Data : Appl Biochem Biotechnol. 2019 Aug 13. Epub 2019 Aug 13. PMID: 31407161

Article Published Date : Aug 12, 2019

Study Type : Animal Study

Additional Links

Substances : beta-Carotene

Diseases : Chemically-Induced Liver Damage

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Problem Substances : Benzene

[+]

Shikonin targets to m6A-modified oxidative damage pathway to alleviate benzene-induced testicular injury.Nov 30, 2022

Click here to read the entire abstract

Pubmed Data : Food Chem Toxicol. 2022 Dec ;170:113496. Epub 2022 Oct 25. PMID: 36306860

Article Published Date : Nov 30, 2022

Study Type : Animal Study

Additional Links

Substances : Shikonin

Diseases : Benzene Toxicity, Testicular Injury: Chemical/Metal Induced

Pharmacological Actions : Antioxidants

Problem Substances : Benzene

[+]

The protective effects of diallyl sulfide (DAS) on benzene-induced leukopenia.Apr 19, 2019

Click here to read the entire abstract

Pubmed Data : Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2019 Apr 20 ;37(4):247-254. PMID: 31177688

Article Published Date : Apr 19, 2019

Study Type : Animal Study

Additional Links

Substances : Diallyl sulfide

Diseases : Benzene Toxicity, Leukopenia

Problem Substances : Benzene

[+]

The protective effects of diallyl sulfide (DAS) on genotoxicity induced by benzene.Aug 19, 2022

Click here to read the entire abstract

Pubmed Data : Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2022 Aug 20 ;40(8):568-572. PMID: 36052584

Article Published Date : Aug 19, 2022

Study Type : Animal Study

Additional Links

Substances : Diallyl sulfide

Diseases : Benzene Toxicity, DNA damage

Pharmacological Actions : Genoprotective

Problem Substances : Benzene

[+]

Benzene and its metabolites are leukemogenic.May 01, 2010

Click here to read the entire abstract

Pubmed Data : Leukemia. 2010 May;24(5):986-91. Epub 2010 Mar 25. PMID: 20339439

Article Published Date : May 01, 2010

Study Type : In Vitro Study

Additional Links

Diseases : Chronic Myeloid Leukemia, Leukemia, Leukemia: Acute myelogenous leukemia (AML)

Problem Substances : Benzene, Benzene Metabolites, Hydroquinone

[+]

Benzene exposure may occur through inhalation, ingestion and topical exposures.Mar 19, 2010

Click here to read the entire abstract

Pubmed Data : Chem Biol Interact. 2010 Mar 19;184(1-2):58-66. Epub 2010 Jan 6. PMID: 20056112

Article Published Date : Mar 19, 2010

Study Type : Review

Additional Links

Problem Substances : Benzene

[+]

Benzene is a well-known carcinogen which appears to exert its deleterious effects through DNA damage.Mar 19, 2010

Click here to read the entire abstract

Pubmed Data : Chem Biol Interact. 2010 Mar 19;184(1-2):269-72. Epub 2010 Jan 6. PMID: 20056111

Article Published Date : Mar 19, 2010

Study Type : Commentary

Additional Links

Diseases : Cancers: All, DNA damage

Problem Substances : Benzene, Benzene Metabolites

[+]

Benzene metabolites may contribute to mutagenesis by overriding apoptosis and attenuating DNA repair capacity. May 01, 1999

Click here to read the entire abstract

Pubmed Data : Mol Pharmacol. 1999 May;55(5):894-901. PMID: 10220568

Article Published Date : May 01, 1999

Study Type : In Vitro Study

Additional Links

Diseases : DNA damage, Oxidative Stress

Problem Substances : Benzene, Benzene Metabolites

[+]

Benzene metabolites oxidize DNA and induced programmed cell death. Nov 15, 1996

Click here to read the entire abstract

Pubmed Data : Cancer Res. 1996 Nov 15;56(22):5172-8. PMID: 8912853

Article Published Date : Nov 15, 1996

Study Type : In Vitro Study

Additional Links

Diseases : DNA damage

Problem Substances : Benzene, Benzene Metabolites

[+]

Crude mineral oil contains benzene as a natural constituent of approximately 0.1%.Jan 01, 1985

Click here to read the entire abstract

Pubmed Data : Am J Ind Med. 1985;7(5-6):375-83. PMID: 4003400

Article Published Date : Jan 01, 1985

Study Type : Commentary

Additional Links

Problem Substances : Benzene, Crude Oil/Petroleum

[+]

European and North American countries limit indoor occupational exposures to benzene between 1.63-3.25mg/m3 (0.5-1 ppm). May 30, 2005

Click here to read the entire abstract

Pubmed Data : Chem Biol Interact. 2005 May 30;153-154:43-53. Epub 2005 Apr 18. PMID: 15935799

Article Published Date : May 30, 2005

Study Type : Review

Additional Links

Problem Substances : Benzene

[+]

Plant isoflavones can prevent adverse effects of benzene on porcine ovarian activity.May 21, 2020

Click here to read the entire abstract

Pubmed Data : Environ Sci Pollut Res Int. 2020 May 22. Epub 2020 May 22. PMID: 32445151

Article Published Date : May 21, 2020

Study Type : In Vitro Study

Additional Links

Substances : Apigenin, Daidzein, Isoflavones, Rutin

Diseases : Benzene Toxicity

Pharmacological Actions : Anti-Apoptotic

Problem Substances : Benzene

[+]

Sodium or potassium benzoate with ascorbic acid has been shown to produce low levels of benzene in fruit-flavored soft drinks.Nov 01, 1993

Click here to read the entire abstract

Pubmed Data : J AOAC Int. 1993 Nov-Dec;76(6):1213-9. PMID: 8286958

Article Published Date : Nov 01, 1993

Study Type : Commentary

Additional Links

Problem Substances : Benzene, Benzene Metabolites, Potassium benzoate, Sodium Benzoate

[+]

Sunscreen significantly enhances the absorption of benzene through the skin. Aug 08, 1997

Click here to read the entire abstract

Pubmed Data : J Toxicol Environ Health. 1997 Aug 8;51(5):447-62. PMID: 9233379

Article Published Date : Aug 08, 1997

Study Type : In Vitro Study

Additional Links

Diseases : Benzene Toxicity

Additional Keywords : Toxic Substance Synergy

Problem Substances : Benzene, Sunscreen

[+]

The consumption of aspartame is associated with higher serum levels of a benzene metabolite associated with blood disorders and leukemia. Jan 01, 2006

Click here to read the entire abstract

Pubmed Data : Biomarkers. 2006 Jan-Feb;11(1):14-27. PMID: 16484134

Article Published Date : Jan 01, 2006

Study Type : Commentary

Additional Links

Diseases : Hematologic Diseases, Leukemia

Problem Substances : Aspartame, Benzene

Research Articles 36
Cumulative Knowledge Score 58
Overall Research Rating GOOD

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This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

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Focus Your Research

Click any topic below to filter + focus research

View the Evidence: 36 Abstracts with Benzene Research

Limited to Members Only

Currently Available Sorting Options

A broccoli seed and sprout extract significantly upregulated detoxification of the tobacco carcinogens benzene, acrolein, and crotonaldehyde.Apr 23, 2022

Benzene and Aspergillus exposures are associated with sick building syndrome.Sep 15, 2009

Benzene exposure at below 1 part per million (1 ppm) causes hematotoxicity in exposed workers.Mar 19, 2010

Benzene exposure in parts per billion has been shown to adversely effect DNA in a manner consisent with increased risk for lymphoma and leukemia.May 30, 2005

Benzene exposure is associated with hypertension, possibly due to disturbance of nitric oxide process.Jul 01, 2007

Benzene exposure is associated with leukemia-associated changes in the peripheral blood lymphocytes of workers.Jan 07, 2011

Benzene exposure near the US permissible limit is associated wtih sperm aneuploidy (chromosomal abnormality).Jan 06, 2010

Crude oil exposure has been linked to acute myelogenous leukemia and multiple myeloma, in part due to benzene.Feb 01, 2008

Electromagnetic fields have a greater influence on women with a predisposition to allergic responses who are exposed to toxic traffic emissions than women without predispostions to allergic responses.Jul 01, 2000

Exposure to toxic compounds from an oil spill is correlated with an increased risk of health effects among pregnant women. Mar 01, 2009

Exposure to various chemicals is associated with increased risk for myelodysplastic syndrome according to the WHO.Feb 01, 2011

Hazardous air pollutants and breast cancer risk in California teachers: a cohort study.Jan 29, 2015

Long-term exposure to low-level ambient benzene significantly increases mortality risk in the general population.Dec 20, 2023

Myeloid leukemia was associated with benzene, a nonspecific group of solvents, occupational pesticides, and working with or near powerlines.Nov 01, 2009

Offshore workers have a higher risk of acute myelogenous leukemia, probably due to benzene exposure.Oct 21, 2004

Pathological protein adducts are associated with benzene and benzene metabolite exposures. May 30, 2005

Sulforaphane detoxifies benzene, an air pollutant, in a dose-dependent manner and may attentuate attenuate associated long-term health risks of air pollution. Jul 03, 2019

Workers exposed to petroleum products may have increased risk for certain leukemias, in part due to benzene exposure.Mar 01, 1997

An extract of moringa oleifera demonstrated chemopreventive and anti-leukemic activities as much as the standard anti-leukemic drug cyclophosphamide.Dec 31, 2013

Antioxidant mechanism of diallyl sulfide in inhibiting leucopenia in peripheral blood induced by benzene.Oct 19, 2019

Benzene exposure induces gut microbiota dysbiosis and metabolic disorder in mice.Feb 24, 2020

Pre-treatment with beta carotene gives protection against nephrotoxicity induced by bromobenzene.Aug 12, 2019

Shikonin targets to m6A-modified oxidative damage pathway to alleviate benzene-induced testicular injury.Nov 30, 2022

The protective effects of diallyl sulfide (DAS) on benzene-induced leukopenia.Apr 19, 2019

The protective effects of diallyl sulfide (DAS) on genotoxicity induced by benzene.Aug 19, 2022

Benzene and its metabolites are leukemogenic.May 01, 2010

Benzene exposure may occur through inhalation, ingestion and topical exposures.Mar 19, 2010

Benzene is a well-known carcinogen which appears to exert its deleterious effects through DNA damage.Mar 19, 2010

Benzene metabolites may contribute to mutagenesis by overriding apoptosis and attenuating DNA repair capacity. May 01, 1999

Benzene metabolites oxidize DNA and induced programmed cell death. Nov 15, 1996

Crude mineral oil contains benzene as a natural constituent of approximately 0.1%.Jan 01, 1985

European and North American countries limit indoor occupational exposures to benzene between 1.63-3.25mg/m3 (0.5-1 ppm). May 30, 2005

Plant isoflavones can prevent adverse effects of benzene on porcine ovarian activity.May 21, 2020

Sodium or potassium benzoate with ascorbic acid has been shown to produce low levels of benzene in fruit-flavored soft drinks.Nov 01, 1993

Sunscreen significantly enhances the absorption of benzene through the skin. Aug 08, 1997

The consumption of aspartame is associated with higher serum levels of a benzene metabolite associated with blood disorders and leukemia. Jan 01, 2006

Benzene Related Articles

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Benzene

View the Evidence:
36 Abstracts with Benzene Research