Butylated Hydroxytoluene (BHT)

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9 Diseases Researched for Butylated Hydroxytoluene (BHT)
NameACCKFocus
Lung Cancer1121Locked
Bladder Cancer34Locked
Chemically-Induced Liver Damage24Locked
Prenatal Chemical Exposures24Locked
DNA damage33Locked
Gastric Cancer23Locked
Inflammation12Locked
Oxidative Stress12Locked
Liver Cancer11Locked

View the Evidence:
44 Abstracts with Butylated Hydroxytoluene (BHT) Research

[+]

Butylated hydroxyanisole (BHA), butylated hydroxytoluene (BHT) and sodium L-ascorbate are capable of promoting chemically-induced forestomach and bladder cancer in male rats. Sep 01, 1984

Pubmed Data : Gann. 1984 Sep;75(9):769-75. PMID: 6500233
Article Published Date : Sep 01, 1984
Study Type : Animal Study
Additional Links
Diseases : Bladder Cancer, Gastric Cancer
Problem Substances : Butylated hydroxyanisole (BHA), Butylated Hydroxytoluene (BHT), Sodium Ascorbate
[+]

Butylated hydroxytoluene (BHT) activates the lung carcinogenic effect of 3-methylcoholanthrene. Jul 15, 1997

Pubmed Data : Cancer Res. 1997 Jul 15;57(14):2832-4. PMID: 9230183
Article Published Date : Jul 15, 1997
Study Type : Animal Study
Additional Links
Diseases : Lung Cancer
Problem Substances : Butylated Hydroxytoluene (BHT)
[+]

Butylated hydroxytoluene (BHT) adversely and permanently effects weight gain in rats exposued in utero and via lactation. Aug 01, 1997

Pubmed Data : Food Chem Toxicol. 1997 Aug;35(8):753-67. PMID: 9350220
Article Published Date : Aug 01, 1997
Study Type : Animal Study
Additional Links
Diseases : Prenatal Chemical Exposures
Problem Substances : Butylated Hydroxytoluene (BHT)
[+]

Butylated hydroxytoluene (BHT) consumption results in increased liver weight and decreased vitamin E levels. Oct 01, 1996

Pubmed Data : Toxicol Lett. 1996 Oct;87(2-3):103-8. PMID: 8914617
Article Published Date : Oct 01, 1996
Study Type : Animal Study
Additional Links
Problem Substances : Butylated Hydroxytoluene (BHT)
[+]

Butylated hydroxytoluene (BHT) exhibits liver toxicity in rats. Apr 01, 1999

Pubmed Data : Histol Histopathol. 1999 Apr;14(2):391-406. PMID: 10212800
Article Published Date : Apr 01, 1999
Study Type : Animal Study
Additional Links
Diseases : Chemically-Induced Liver Damage
Problem Substances : Butylated Hydroxytoluene (BHT)
[+]

Butylated hydroxytoluene (BHT) has been used to induce lung and liver toxicity in experiments with rats. Nov 01, 2003

Pubmed Data : Indian J Exp Biol. 2003 Nov;41(11):1294-9. PMID: 15332500
Article Published Date : Nov 01, 2003
Study Type : Animal Study
Additional Links
Problem Substances : Butylated Hydroxytoluene (BHT)
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Butylated hydroxytoluene (BHT) is associated abnormal changes of the thyroid gland in rats. Feb 01, 1982

Pubmed Data : Toxicol Lett. 1982 Feb;10(2-3):239-44. PMID: 7080091
Article Published Date : Feb 01, 1982
Study Type : Animal Study
Additional Links
Problem Substances : Butylated Hydroxytoluene (BHT)
[+]

Butylated hydroxytoluene (BHT) is associated hemorrhagic toxicosis in rats. Jul 01, 1981

Pubmed Data : Acta Pharmacol Toxicol (Copenh). 1981 Jul;49(1):14-20. PMID: 7336960
Article Published Date : Jul 01, 1981
Study Type : Animal Study
Additional Links
Problem Substances : Butylated Hydroxytoluene (BHT)
[+]

Butylated hydroxytoluene (BHT) is associated with behavioral and developmental effects in rats in utero and in the lactation period. Jan 01, 1980

Pubmed Data : Toxicology. 1980;16(3):247-58. PMID: 7191588
Article Published Date : Jan 01, 1980
Study Type : Animal Study
Additional Links
Diseases : Prenatal Chemical Exposures
Problem Substances : Butylated Hydroxytoluene (BHT)
[+]

Butylated hydroxytoluene (BHT) is associated with hematological changes in rats. Oct 01, 1985

Pubmed Data : Food Chem Toxicol. 1985 Oct;23(10):937-9. PMID: 3934053
Article Published Date : Oct 01, 1985
Study Type : Animal Study
Additional Links
Problem Substances : Butylated Hydroxytoluene (BHT)
[+]

Butylated hydroxytoluene (BHT) is associated with lung injury in mice. Jan 01, 1977

Pubmed Data : Lab Invest. 1977 Jan;36(1):26-32. PMID: 830993
Article Published Date : Jan 01, 1977
Study Type : Animal Study
Additional Links
Problem Substances : Butylated Hydroxytoluene (BHT)
[+]

Butylated hydroxytoluene (BHT) is associated with potentially adverse changes in the liver. Jul 01, 1989

Pubmed Data : Cancer Lett. 1989 Jul 1;46(1):31-6. PMID: 2736505
Article Published Date : Jul 01, 1989
Study Type : Animal Study
Additional Links
Problem Substances : Butylated Hydroxytoluene (BHT)
[+]

Butylated hydroxytoluene (BHT) may act as a lung cancer promoting agent - Article 2. Aug 01, 2002

Pubmed Data : Chem Res Toxicol. 2002 Aug;15(8):1106-12. PMID: 12184795
Article Published Date : Aug 01, 2002
Study Type : Animal Study
Additional Links
Diseases : Lung Cancer
Problem Substances : Butylated Hydroxytoluene (BHT)
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Butylated hydroxytoluene (BHT) may act as a lung cancer promoting agent - Article 3. Mar 07, 2001

Pubmed Data : Toxicology. 2001 Mar 7;160(1-3):197-205. PMID: 11246140
Article Published Date : Mar 07, 2001
Study Type : Animal Study
Additional Links
Diseases : Lung Cancer
Problem Substances : Butylated Hydroxytoluene (BHT)
[+]

Butylated hydroxytoluene (BHT) may act as a lung cancer promoting agent - Article 4. Apr 01, 2001

Pubmed Data : Exp Lung Res. 2001 Apr-May;27(3):197-216. PMID: 11293324
Article Published Date : Apr 01, 2001
Study Type : Animal Study
Additional Links
Diseases : Inflammation, Lung Cancer
Problem Substances : Butylated Hydroxytoluene (BHT)
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Butylated hydroxytoluene (BHT) may act as a lung cancer promoting agent - Article 5. Dec 01, 2000

Pubmed Data : Exp Lung Res. 2000 Dec;26(8):709-30. PMID: 11195466
Article Published Date : Dec 01, 2000
Study Type : Animal Study
Additional Links
Diseases : Lung Cancer
Problem Substances : Butylated Hydroxytoluene (BHT)
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Butylated hydroxytoluene (BHT) may act as a lung cancer promoting agent - Article 6. Oct 18, 1999

Pubmed Data : Cancer Lett. 1999 Oct 18;145(1-2):101-6. PMID: 10530776
Article Published Date : Oct 18, 1999
Study Type : Animal Study
Additional Links
Diseases : Lung Cancer
Problem Substances : Butylated Hydroxytoluene (BHT)
[+]

Butylated hydroxytoluene (BHT) may act as a lung cancer promoting agent - Article 7. Sep 15, 1998

Pubmed Data : Toxicology. 1998 Sep 15;130(2-3):115-27. PMID: 9865479
Article Published Date : Sep 15, 1998
Study Type : Animal Study
Additional Links
Diseases : Lung Cancer
Problem Substances : Butylated Hydroxytoluene (BHT)
[+]

Butylated hydroxytoluene (BHT) may act as a lung cancer promoting agent - Article 8. Aug 01, 1996

Pubmed Data : Cancer Res. 1996 Aug 1;56(15):3480-5. PMID: 8758915
Article Published Date : Aug 01, 1996
Study Type : Animal Study
Additional Links
Problem Substances : Butylated Hydroxytoluene (BHT)
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Butylated hydroxytoluene (BHT) may act as a lung cancer promoting agent - Article 9. Aug 01, 2008

Pubmed Data : Chem Res Toxicol. 2008 Aug;21(8):1631-41. Epub 2008 Jul 3. PMID: 18597497
Article Published Date : Aug 01, 2008
Study Type : Animal Study
Additional Links
Diseases : Lung Cancer
Problem Substances : Butylated Hydroxytoluene (BHT)
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Butylated hydroxytoluene (BHT) may act as a lung cancer promoting agent - Article 9.Feb 01, 1978

Pubmed Data : Toxicology. 1978 Feb;9(1-2):137-46. PMID: 653734
Article Published Date : Feb 01, 1978
Study Type : Animal Study
Additional Links
Diseases : Lung Cancer
Problem Substances : Butylated Hydroxytoluene (BHT)
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Butylated hydroxytoluene (BHT) may act as a lung cancer promoting agent. Mar 06, 2003

Pubmed Data : Chem Biol Interact. 2003 Mar 6;145(1):41-51. PMID: 12606153
Article Published Date : Mar 06, 2003
Study Type : Animal Study
Additional Links
Diseases : Lung Cancer
Problem Substances : Butylated Hydroxytoluene (BHT)
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Butylated hydroxytoluene (BHT) may have deleterious effect on blood coagulation. Feb 01, 1986

Pubmed Data : Arch Toxicol. 1986 Feb;58(3):177-81. PMID: 3964081
Article Published Date : Feb 01, 1986
Study Type : Animal Study
Additional Links
Problem Substances : Butylated Hydroxytoluene (BHT)
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Butylated hydroxytoluene (BHT) may potentiate the neurotoxicty and mortality associated with methylmercury toxicity. Jul 01, 1978

Pubmed Data : Bull Environ Contam Toxicol. 1978 Jul;20(1):102-10. PMID: 698413
Article Published Date : Jul 01, 1978
Study Type : Animal Study
Additional Links
Problem Substances : Butylated Hydroxytoluene (BHT)
[+]

Butylated hydroxytoluene (BHT) potentiates vitamin A induced liver damage in rats. Aug 01, 1987

Pubmed Data : Toxicol Appl Pharmacol. 1987 Aug;90(1):1-9. PMID: 3629584
Article Published Date : Aug 01, 1987
Study Type : Animal Study
Additional Links
Diseases : Chemically-Induced Liver Damage
Additional Keywords : Drug-Plant-Vitamin Synergies
Problem Substances : Butylated Hydroxytoluene (BHT)
[+]

Dietary protein levels increase the toxic effects of butylated hydroxytoluene (BHT) in rats. Jan 01, 1983

Pubmed Data : Drug Nutr Interact. 1983;2(1):57-68. PMID: 6678747
Article Published Date : Jan 01, 1983
Study Type : Animal Study
Additional Links
Problem Substances : Butylated Hydroxytoluene (BHT)
[+]

Intravenous butylated hydroxytoluene (BHT) is associated with lung damage in mice - Article 2. Dec 01, 1977

Pubmed Data : J Toxicol Environ Health. 1977 Dec;3(5-6):829-36. PMID: 599582
Article Published Date : Dec 01, 1977
Study Type : Animal Study
Additional Links
Problem Substances : Butylated Hydroxytoluene (BHT)
[+]

Intravenous butylated hydroxytoluene (BHT) is associated with lung damage in mice. Oct 01, 1995

Pubmed Data : Indian J Exp Biol. 1995 Oct;33(10):796-7. PMID: 8575813
Article Published Date : Oct 01, 1995
Study Type : Animal Study
Additional Links
Problem Substances : Butylated Hydroxytoluene (BHT)
[+]

Long-term administration of butyl hydroxytoluene (BHT) is capable of inducing pathological oxidative and metabolic alterations. Jan 01, 2006

Pubmed Data : Exp Toxicol Pathol. 2006 Jan;57(3):221-6. Epub 2005 Dec 9. PMID: 16338125
Article Published Date : Jan 01, 2006
Study Type : Animal Study
Additional Links
Diseases : Oxidative Stress
Problem Substances : Butylated Hydroxytoluene (BHT)
[+]

Retinyl acetate when combined with butylated hydroxytoluene (BHT) resulted in hepatic fibrosis and bile duct hyperplasia in rats. Oct 01, 1986

Pubmed Data : Cancer Res. 1986 Oct;46(10):5264-9. PMID: 3093062
Article Published Date : Oct 01, 1986
Study Type : Animal Study
Additional Links
Problem Substances : Butylated Hydroxytoluene (BHT)
[+]

Butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT) are capable of promoting urinary bladder carcinogenesis. Jan 01, 1983

Pubmed Data : Carcinogenesis. 1983;4(7):895-9. PMID: 6135514
Article Published Date : Jan 01, 1983
Study Type : In Vitro Study
Additional Links
Diseases : Bladder Cancer
Problem Substances : Butylated hydroxyanisole (BHA), Butylated Hydroxytoluene (BHT)
[+]

Butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT) have proxidant properties, capable of inducing cytotoxicity and programmed cell death. Nov 01, 2003

Pubmed Data : Anticancer Res. 2003 Nov-Dec;23(6C):4693-701. PMID: 14981915
Article Published Date : Nov 01, 2003
Study Type : In Vitro Study
Additional Links
Problem Substances : Butylated hydroxyanisole (BHA), Butylated Hydroxytoluene (BHT)
[+]

Butylated hydroxyanisole (BHA), butylated hydroxytoluene (BHT) and sodium L-ascorbate may promote certain cancers. Jan 01, 1985

Pubmed Data : Crit Rev Toxicol. 1985;15(2):109-50. PMID: 3899519
Article Published Date : Jan 01, 1985
Study Type : Review
Additional Links
Diseases : Bladder Cancer, Gastric Cancer, Liver Cancer
Additional Keywords : Drug-Plant-Vitamin Synergies
Problem Substances : Butylated hydroxyanisole (BHA), Butylated Hydroxytoluene (BHT), Sodium Ascorbate
[+]

Butylated hydroxytoluene (BHT) and butylated hydroxyanisole (BHA) have an additive effect on the activation of aflatoxin B1 and bezo[a]pyrene. Sep 26, 1997

Pubmed Data : Toxicology. 1997 Sep 26;122(1-2):61-72. PMID: 9274802
Article Published Date : Sep 26, 1997
Study Type : In Vitro Study
Additional Links
Problem Substances : Butylated hydroxyanisole (BHA), Butylated Hydroxytoluene (BHT)
[+]

Butylated hydroxytoluene (BHT) enhances urethan tumorigenesis in mouse lung cells. Feb 01, 1977

Pubmed Data : J Natl Cancer Inst. 1977 Feb;58(2):301-5. PMID: 833878
Article Published Date : Feb 01, 1977
Study Type : In Vitro Study
Additional Links
Diseases : Lung Cancer
Problem Substances : Butylated Hydroxytoluene (BHT)
[+]

Butylated hydroxytoluene (BHT) exhibits direct and indirect genotoxic activity. Aug 01, 1998

Pubmed Data : Biochem Pharmacol. 1998 Aug 1;56(3):361-70. PMID: 9744574
Article Published Date : Aug 01, 1998
Study Type : In Vitro Study
Additional Links
Diseases : DNA damage
Problem Substances : Butylated Hydroxytoluene (BHT)
[+]

Butylated hydroxytoluene (BHT) may break down into toxic metabolites. Mar 01, 1991

Pubmed Data : Drug Metab Dispos. 1991 Mar-Apr;19(2):467-72. PMID: 1676656
Article Published Date : Mar 01, 1991
Study Type : In Vitro Study
Additional Links
Problem Substances : Butylated Hydroxytoluene (BHT)
[+]

Butylated hydroxytoluene (BHT) may contribute to allergic diseases such as allergic rhinitis and asthma.Sep 01, 2007

Pubmed Data : Toxicol Appl Pharmacol. 2007 Sep 1;223(2):164-72. Epub 2007 May 24. PMID: 17604070
Article Published Date : Sep 01, 2007
Study Type : In Vitro Study
Additional Links
Problem Substances : Butylated Hydroxytoluene (BHT)
[+]

Butylated hydroxytoluene (BHT) may contribute to increasing chromosomal damage induced by radiation. Nov 01, 2006

Pubmed Data : Mutagenesis. 2006 Nov;21(6):405-10. Epub 2006 Oct 25. PMID: 17065160
Article Published Date : Nov 01, 2006
Study Type : In Vitro Study
Additional Links
Problem Substances : Butylated Hydroxytoluene (BHT)
[+]

Butylated hydroxytoluene (BHT) may contribute to tumor promotion. Sep 01, 1993

Pubmed Data : Chem Res Toxicol. 1993 Sep-Oct;6(5):731-8. PMID: 8292753
Article Published Date : Sep 01, 1993
Study Type : In Vitro Study
Additional Links
Problem Substances : Butylated Hydroxytoluene (BHT)
[+]

Butylated hydroxytoluene (BHT) may function as a tumor promoting agent, as demonstrated in mouse skin cells. Jul 01, 1989

Pubmed Data : Carcinogenesis. 1989 Jul;10(7):1261-8. PMID: 2472232
Article Published Date : Jul 01, 1989
Study Type : In Vitro Study
Additional Links
Problem Substances : Butylated Hydroxytoluene (BHT)
[+]

Butylated hydroxytoluene (BHT) metabolites appear to promote tumor formation. Feb 01, 1991

Pubmed Data : Proc Natl Acad Sci U S A. 1991 Feb 1;88(3):946-50. PMID: 1846971
Article Published Date : Feb 01, 1991
Study Type : In Vitro Study
Additional Links
Problem Substances : Butylated Hydroxytoluene (BHT)
[+]

Butylated hydroxytoluene (BHT) metabolites damages DNA through the generation of oxygen radicals. Jan 01, 1993

Pubmed Data : Arch Toxicol. 1993;67(8):552-7. PMID: 8285854
Article Published Date : Jan 01, 1993
Study Type : In Vitro Study
Additional Links
Diseases : DNA damage
Problem Substances : Butylated Hydroxytoluene (BHT)
[+]

Various food additives, preservatives, fungicides and artificial sweeteners have been demonstrated to have the potential to damage DNA in gastrointestinal organs. Aug 26, 2002

Pubmed Data : Mutat Res. 2002 Aug 26;519(1-2):103-19. PMID: 12160896
Article Published Date : Aug 26, 2002
Study Type : In Vitro Study
Additional Links
Diseases : DNA damage
Problem Substances : Biphenyl, Butylated hydroxyanisole (BHA), Butylated Hydroxytoluene (BHT), Saccharin, Sodium Cyclamate, Sodium o-phenylphenol, Sucralose (aka Splenda), Thiabendazole

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