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11 Diseases Researched for Caffeine

Name	AC	CK
Abortion: Spontaneous	3	30
Miscarriage	3	30
Dopamine Deficiency	1	10
Hypoglycemia	1	10
Menarche: Early Onset	1	10
Neural Tube Defects	1	10
Premature Puberty	1	10
Prenatal Nutrition: Health of the Offspring	1	10
Spina Bifida	1	10
Tourette Syndrome	1	10
Calcium Homeostasis: Impairment	1	2

1 Adverse Pharmacological Actions Researched for Caffeine

Name	AC	CK	Focus
Teratogenic	4	40

Research Articles 9
Cumulative Knowledge Score 14
Overall Research Rating GOOD

View the Evidence:
9 Abstracts with Caffeine Research

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Acute ingestion of caffeine is associated with sympathoadrenal activation and awareness of hypoglycemia at a glucose level not usually considered hypoglycemic.Oct 15, 1993

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Pubmed Data : Ann Intern Med. 1993 Oct 15;119(8):799-804. PMID: 8379601

Article Published Date : Oct 15, 1993

Study Type : Human Study

Additional Links

Diseases : Hypoglycemia

Problem Substances : Caffeine

[+]

Caffeine has effects on dopaminergic neurotransmission in the human brain, which may be differential in the striatum and the thalamus.Feb 09, 2004

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Pubmed Data : Neuroreport. 2004 Feb 9 ;15(2):281-5. PMID: 15076753

Article Published Date : Feb 09, 2004

Study Type : Human Study

Additional Links

Diseases : Dopamine Deficiency

Pharmacological Actions : Dopaminergic

Problem Substances : Caffeine

[+]

Consumption of caffeinated and artificially sweetened soft drinks was positively associated with risk of early menarche in a US cohort of African American and Caucasian girls.Jul 14, 2015

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Pubmed Data : Am J Clin Nutr. 2015 Jul 15. Epub 2015 Jul 15. PMID: 26178725

Article Published Date : Jul 14, 2015

Study Type : Human Study

Additional Links

Diseases : Menarche: Early Onset, Premature Puberty

Additional Keywords : Increased Risk

Problem Substances : Artificially Sweetened Beverages, Caffeine

[+]

Heavy caffeine consumption (especially when there is nausea) during pregnancy may increase the risk of spontaneous abortion.May 01, 1991

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Pubmed Data : Epidemiology. 1991 May;2(3):168-74. PMID: 2054397

Article Published Date : May 01, 1991

Study Type : Human Study

Additional Links

Diseases : Abortion: Spontaneous, Miscarriage

Problem Substances : Caffeine

Adverse Pharmacological Actions : Teratogenic

[+]

Maternal caffeine consumption has been linked to neural tube defects.Nov 01, 2009

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Pubmed Data : Birth Defects Res A Clin Mol Teratol. 2009 Nov;85(11):879-89. PMID: 19711421

Article Published Date : Nov 01, 2009

Study Type : Human Study

Additional Links

Diseases : Neural Tube Defects, Prenatal Nutrition: Health of the Offspring, Spina Bifida

Problem Substances : Caffeine

Adverse Pharmacological Actions : Teratogenic

[+]

Maternal caffeine consumption is associated with an increased risk of spontaneous abortion.May 01, 1996

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Pubmed Data : Epidemiology. 1996 May;7(3):250-5. PMID: 8728437

Article Published Date : May 01, 1996

Study Type : Human Study

Additional Links

Diseases : Abortion: Spontaneous, Miscarriage

Problem Substances : Caffeine, Coffee, Tea

Adverse Pharmacological Actions : Teratogenic

[+]

The consumption of caffeine containing substances, e.g. coke and coffee, worsen tics in Tourette syndrome probably due to its dopaminergic activities.Apr 01, 2008

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Pubmed Data : Acta Paediatr. 2008 Apr;97(4):442-6. Epub 2008 Feb 27. PMID: 18307557

Article Published Date : Apr 01, 2008

Study Type : Human Study

Additional Links

Diseases : Tourette Syndrome

Problem Substances : Caffeine, Sugary soda

[+]

The ingestion of caffeine may increase the risk of an early spontaneous abortion among non-smoking women carrying fetuses with normal karyotypes.Dec 21, 2000

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Pubmed Data : N Engl J Med. 2000 Dec 21;343(25):1839-45. PMID: 11117975

Article Published Date : Dec 21, 2000

Study Type : Human Study

Additional Links

Diseases : Abortion: Spontaneous, Miscarriage

Problem Substances : Caffeine

Adverse Pharmacological Actions : Teratogenic

[+]

Animal study: Daily intake of coffee/caffeine caused serious adverse effects on calcium metabolismDec 31, 2009

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Braz Dent J. 2010 ;21(3):199-204. PMID: 21203700

Article Published Date : Dec 31, 2009

Study Type : Animal Study

Additional Links

Diseases : Calcium Homeostasis: Impairment

Problem Substances : Caffeine, Coffee

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Focus Your Research

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View the Evidence: 9 Abstracts with Caffeine Research

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Currently Available Sorting Options

Acute ingestion of caffeine is associated with sympathoadrenal activation and awareness of hypoglycemia at a glucose level not usually considered hypoglycemic.Oct 15, 1993

Caffeine has effects on dopaminergic neurotransmission in the human brain, which may be differential in the striatum and the thalamus.Feb 09, 2004

Consumption of caffeinated and artificially sweetened soft drinks was positively associated with risk of early menarche in a US cohort of African American and Caucasian girls.Jul 14, 2015

Heavy caffeine consumption (especially when there is nausea) during pregnancy may increase the risk of spontaneous abortion.May 01, 1991

Maternal caffeine consumption has been linked to neural tube defects.Nov 01, 2009

Maternal caffeine consumption is associated with an increased risk of spontaneous abortion.May 01, 1996

The consumption of caffeine containing substances, e.g. coke and coffee, worsen tics in Tourette syndrome probably due to its dopaminergic activities.Apr 01, 2008

The ingestion of caffeine may increase the risk of an early spontaneous abortion among non-smoking women carrying fetuses with normal karyotypes.Dec 21, 2000

Animal study: Daily intake of coffee/caffeine caused serious adverse effects on calcium metabolismDec 31, 2009

Caffeine Related Articles

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Caffeine

View the Evidence:
9 Abstracts with Caffeine Research