Chlorpyrifos

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5 Diseases Researched for Chlorpyrifos
NameACCKFocus
Multiple Sclerosis110Locked
Pesticide Toxicity 110Locked
Hypothyroidism12Locked
Lead Poisoning12Locked
Pesticide-Induced Toxicity: Organophosphates12Locked
1 Adverse Pharmacological Actions Researched for Chlorpyrifos
NameACCKFocus
Immunotoxic110Locked

View the Evidence:
78 Abstracts with Chlorpyrifos Research

[+]

Adverse neurodevelopmental effects were associated with early childhood chlorpyrifos exposure.May 09, 2019

Pubmed Data : Environ Pollut. 2019 May 10 ;251:538-546. Epub 2019 May 10. PMID: 31108286
Article Published Date : May 09, 2019
Study Type : Human Study
Additional Links
Diseases : Neurodevelopmental Disorders, Pesticide Toxicity
Problem Substances : Chlorpyrifos
[+]

Exposure to pesticides like chlorpyrifos may contribute to the pathogenesis of multiple sclerosis. May 01, 2002

Pubmed Data : Arch Environ Health. 2002 May-Jun;57(3):181-7. PMID: 12507170
Article Published Date : May 01, 2002
Study Type : Human Study
Additional Links
Diseases : Multiple Sclerosis, Pesticide Toxicity
Problem Substances : Chlorpyrifos, Pesticides
Adverse Pharmacological Actions : Immunotoxic
[+]

Honey supplementation enhanced DNA repair activity in a residential population chronically exposed to pesticides.Apr 29, 2016

Pubmed Data : Mol Nutr Food Res. 2016 Apr 30. Epub 2016 Apr 30. PMID: 27129605
Article Published Date : Apr 29, 2016
Study Type : Human Study
Additional Links
Substances : Honey
Diseases : Pesticide Toxicity
Pharmacological Actions : DNA Repair Up-regulation, Genoprotective
Problem Substances : Chlorpyrifos, Glyphosate
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Lymphocytes DNA damages and exposure to chlorpyrifos, deltamethrin, penconazole, copper oxicloride.Nov 15, 2018

Pubmed Data : Biomarkers. 2018 Nov 16:1-13. Epub 2018 Nov 16. PMID: 30514118
Article Published Date : Nov 15, 2018
Study Type : Human Study
Additional Links
Diseases : DNA damage, Pesticide Toxicity
Problem Substances : Chlorpyrifos, Deltamethrin, Pesticides
[+]

Magnesium chloride neutralized the effects of chlorpyrifos.May 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmacol Res Perspect. 2018 Jun ;6(3):e00401. Epub 2018 Apr 30. PMID: 29736246
Article Published Date : May 31, 2018
Study Type : Human Study
Additional Links
Substances : magnesium chloride
Diseases : Pesticide Toxicity
Problem Substances : Chlorpyrifos
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This case-control study found that chlorpyrifos and some other pesticide exposure during pregnancy was positively associated with developmental delay in children aged under 5 years.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : F1000Res. 2020 ;9:1501. Epub 2020 Dec 23. PMID: 34557296
Article Published Date : Dec 31, 2019
Study Type : Human Study
Additional Links
Diseases : Developmental Disorder: Children, Pesticide Toxicity
Additional Keywords : Increased Risk
Problem Substances : Chlorpyrifos, Pesticides
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This study found deficits in 9-month motor function in infants with prenatal exposure to naled and chlorpyrifos.Aug 31, 2017

Pubmed Data : Environ Int. 2017 Sep ;106:248-256. Epub 2017 Jun 8. PMID: 28602489
Article Published Date : Aug 31, 2017
Study Type : Human Study
Additional Links
Diseases : Pesticide Toxicity , Prenatal Chemical Exposures
Problem Substances : Chlorpyrifos
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This study provides preliminary evidence of an association between occupational exposure to chlorpyrifos and ADHD symptoms among adolescent pesticide applicators.May 07, 2019

Pubmed Data : Neurotoxicology. 2019 May 8 ;74:1-6. Epub 2019 May 8. PMID: 31077682
Article Published Date : May 07, 2019
Study Type : Human Study
Additional Links
Diseases : Attention Deficit Disorder with Hyperactivity, Pesticide Toxicity
Additional Keywords : Increased Risk
Problem Substances : Chlorpyrifos
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A 6-Gingerol-rich fraction from ginger protective effects on chlorpyrifos induced toxicity in the brain and reproductive organs of rats.May 24, 2017

Pubmed Data : Chem Biol Interact. 2017 May 25 ;270:15-23. Epub 2017 Mar 31. PMID: 28373059
Article Published Date : May 24, 2017
Study Type : Animal Study
Additional Links
Substances : Gingerol
Diseases : Pesticide Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
Problem Substances : Chlorpyrifos
[+]

A neuroprotective role of kaempferol against chlorpyrifos-induced oxidative stress and memory deficits.Oct 31, 2018

Pubmed Data : Pestic Biochem Physiol. 2018 Nov ;152:29-37. Epub 2018 Aug 13. PMID: 30497708
Article Published Date : Oct 31, 2018
Study Type : Animal Study
Additional Links
Diseases : Memory Disorders, Pesticide Toxicity
Pharmacological Actions : Antioxidants, Neuroprotective Agents, Nrf2 activation
Problem Substances : Chlorpyrifos
[+]

Aerobic exercise and eugenol supplementation ameliorated liver injury induced by chlorpyrifos.Feb 24, 2020

Pubmed Data : Environ Toxicol. 2020 Feb 25. Epub 2020 Feb 25. PMID: 32096903
Article Published Date : Feb 24, 2020
Study Type : Animal Study
Additional Links
Substances : Eugenol
Diseases : Chemically-Induced Liver Damage, Pesticide Toxicity
Therapeutic Actions : Exercise: Aerobic
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective
Problem Substances : Chlorpyrifos
[+]

Alpha lipoic acid possess protective effects against chlorpyrifos induced liver injury.Feb 22, 2018

Pubmed Data : Environ Toxicol Pharmacol. 2018 Feb 23 ;59:17-23. Epub 2018 Feb 23. PMID: 29500983
Article Published Date : Feb 22, 2018
Study Type : Animal Study
Additional Links
Substances : Alpha-Lipoic Acid
Diseases : Chemically-Induced Liver Damage, Pesticide Toxicity
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Hepatoprotective
Problem Substances : Chlorpyrifos, Pesticides
[+]

Alpha-lipoic acid could help protect against the harmful effects of pesticides. Dec 22, 2015

Pubmed Data : Toxicol Ind Health. 2015 Dec 23. Epub 2015 Dec 23. PMID: 26697883
Article Published Date : Dec 22, 2015
Study Type : Animal Study
Additional Links
Substances : Alpha-Lipoic Acid
Diseases : Pesticide Toxicity
Pharmacological Actions : Anti-Inflammatory Agents
Problem Substances : Chlorpyrifos, Deltamethrin
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Alpha-lipoic acid could protect against chlorpyrifos and deltamethrin.May 06, 2018

Pubmed Data : Environ Sci Pollut Res Int. 2018 May 7. Epub 2018 May 7. PMID: 29736639
Article Published Date : May 06, 2018
Study Type : Animal Study
Additional Links
Substances : Alpha-Lipoic Acid
Diseases : Oxidative Stress, Pesticide Toxicity
Pharmacological Actions : Antioxidants
Problem Substances : Chlorpyrifos, Deltamethrin
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Antioxidant and anti-inflammatory potential of thymoquinone and lycopene mitigate the chlorpyrifos-induced toxic neuropathy.Sep 19, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmaceuticals (Basel). 2021 Sep 20 ;14(9). Epub 2021 Sep 20. PMID: 34577640
Article Published Date : Sep 19, 2021
Study Type : Animal Study
Additional Links
Substances : Lycopene, Thymoquinone
Diseases : Pesticide Toxicity
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Chlorpyrifos
[+]

Atrazine-induced up-regulation of CtCYP6EX3 enhanced the toxicity of chlorpyrifos.Oct 31, 2017

Pubmed Data : Chemosphere. 2017 Nov ;186:68-77. Epub 2017 Jul 27. PMID: 28768160
Article Published Date : Oct 31, 2017
Study Type : Insect Study
Additional Links
Diseases : Pesticide Toxicity
Additional Keywords : Synergistic Toxicity
Problem Substances : Chlorpyrifos, Pesticides
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Beneficial effects of crataegus oxyacantha extract on neurobehavioral deficits and brain tissue damages induced by an insecticide mixtures.May 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2019 Jun ;114:108795. Epub 2019 Mar 22. PMID: 30909143
Article Published Date : May 31, 2019
Study Type : Animal Study
Additional Links
Substances : Hawthorn
Diseases : Pesticide Toxicity
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Chlorpyrifos, Deltamethrin
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Caffeic acid phenethyl ester prevented the neurodegenerations in brain tissue in chlorpyrifos induced Parkinson's disease.Dec 31, 2017

Pubmed Data : Pestic Biochem Physiol. 2018 Jan ;144:36-41. Epub 2017 Nov 10. PMID: 29463406
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Caffeic acid phenethyl ester
Diseases : Parkinson's Disease, Pesticide Toxicity
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Chlorpyrifos
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Carnosic acid alleviates chlorpyrifos-induced oxidative stress and inflammation in mice cerebral and ocular tissues.Jan 21, 2020

Pubmed Data : Environ Sci Pollut Res Int. 2020 Jan 22. Epub 2020 Jan 22. PMID: 31965510
Article Published Date : Jan 21, 2020
Study Type : Animal Study
Additional Links
Substances : Carnosic Acid
Diseases : Brain: Oxidative Stress, Brain Inflammation , Pesticide Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Interleukin-6 Downregulation
Problem Substances : Chlorpyrifos
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Chlorpyrifos and chlorpyrifos oxon impair the transport of membrane bound organelles in rat cortical axons.Jun 11, 2017

Pubmed Data : Neurotoxicology. 2017 Jun 12 ;62:111-123. Epub 2017 Jun 12. PMID: 28600141
Article Published Date : Jun 11, 2017
Study Type : Animal Study
Additional Links
Diseases : Pesticide Toxicity
Problem Substances : Chlorpyrifos
Adverse Pharmacological Actions : Neurotoxic
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Chlorpyrifos and dichlorvos induced oxidative and neurogenic damage and icreases anxiety-like behaviour in animals.Nov 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Toxics. 2018 Dec 1 ;6(4). Epub 2018 Dec 1. PMID: 30513797
Article Published Date : Nov 30, 2018
Study Type : Animal Study
Additional Links
Diseases : Anxiety, Oxidative Stress, Pesticide Toxicity
Problem Substances : Chlorpyrifos, Dichlorvos
Adverse Pharmacological Actions : Neurotoxic
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Chlorpyrifos induced cytotoxicity may be explained by NF-κB activated inflammatory cascade.Mar 31, 2018

Pubmed Data : Environ Sci Pollut Res Int. 2018 Apr ;25(12):12072-12082. Epub 2018 Feb 16. PMID: 29453720
Article Published Date : Mar 31, 2018
Study Type : Animal Study
Additional Links
Diseases : Inflammation, Pesticide Toxicity
Problem Substances : Chlorpyrifos
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Chlorpyrifos may act as a breast cancer risk factor.Oct 01, 2018

Pubmed Data : J Steroid Biochem Mol Biol. 2018 Oct 2. Epub 2018 Oct 2. PMID: 30290214
Article Published Date : Oct 01, 2018
Study Type : Animal Study
Additional Links
Diseases : Breast Cancer: Chemically-Induced, Pesticide Toxicity
Additional Keywords : Epigenetic Modification, Risk Factors
Problem Substances : Chlorpyrifos
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Chlorpyrifos-induced reproductive toxicity in rats.Jul 31, 2019

Pubmed Data : Chemosphere. 2019 Aug ;229:94-102. Epub 2019 May 4. PMID: 31078036
Article Published Date : Jul 31, 2019
Study Type : Animal Study
Additional Links
Diseases : Infertility: Male, Pesticide Toxicity
Problem Substances : Chlorpyrifos
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Chronic exposure to chlorpyrifos is associated with higher sleep apnea index and modifies respiratory patterns in sleeping juvenile and adult rats.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2018 ;13(1):e0191237. Epub 2018 Jan 22. PMID: 29357379
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Diseases : Pesticide Toxicity , Sleep Apnea
Additional Keywords : Risk Factors
Problem Substances : Chlorpyrifos, Pesticides
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Clorpyrifos significantly altered the gut microbiota composition.May 31, 2016

Pubmed Data : Chemosphere. 2016 Jun ;153:287-93. Epub 2016 Mar 26. PMID: 27018521
Article Published Date : May 31, 2016
Study Type : Animal Study
Additional Links
Diseases : Dysbiosis, Lipopolysaccharide-Induced Toxicity, Pesticide Toxicity
Additional Keywords : Microbiota
Problem Substances : Chlorpyrifos, Pesticides
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Curcumin has an ameliorative effect on chlorpyrifos-induced biochemical changes in Cyprinus carpio. Apr 29, 2018

Pubmed Data : Ecotoxicol Environ Saf. 2018 Apr 30 ;151:49-54. Epub 2018 Jan 3. PMID: 29306070
Article Published Date : Apr 29, 2018
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Pesticide Toxicity
Pharmacological Actions : Antioxidants
Problem Substances : Chlorpyrifos
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Disruption of kidney metabolism in rats after subchronic combined exposure to low-dose cadmium and chlorpyrifos.Nov 29, 2018

Pubmed Data : Chem Res Toxicol. 2018 Nov 30. Epub 2018 Nov 30. PMID: 30500169
Article Published Date : Nov 29, 2018
Study Type : Animal Study
Additional Links
Diseases : Kidney Damage: Chemically-Induced, Pesticide Toxicity
Additional Keywords : Synergistic Toxicity
Problem Substances : Cadmium, Chlorpyrifos
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Excessive pesticide use in the Sebitoli area may contribute to facial dysplasia in chimpanzees and baboons.Apr 24, 2017

Pubmed Data : Sci Total Environ. 2017 Apr 25 ;598:647-656. Epub 2017 Apr 25. PMID: 28454037
Article Published Date : Apr 24, 2017
Study Type : Animal Study
Additional Links
Diseases : Pesticide Toxicity
Problem Substances : Chlorpyrifos, Cypermethrin, Dichloro-diphenyl-trichloroethane (DDT) , Glyphosate, Pesticides
[+]

Hesperidin protects against the chlorpyrifos-induced chronic hepato-renal toxicity.Apr 27, 2021

Pubmed Data : Environ Toxicol. 2021 Apr 28. Epub 2021 Apr 28. PMID: 33908150
Article Published Date : Apr 27, 2021
Study Type : Animal Study
Additional Links
Substances : Hesperidin
Diseases : Chemically-Induced Liver Damage, Kidney Damage: Chemically-Induced, Pesticide Toxicity
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Hepatoprotective, Renoprotective
Problem Substances : Chlorpyrifos
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Imidacloprid and chlorpyrifos insecticides impair migratory ability in a seed-eating songbird.Jan 08, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2017 11 9 ;7(1):15176. Epub 2017 Nov 9. PMID: 29123163
Article Published Date : Jan 08, 2017
Study Type : Animal Study
Additional Links
Diseases : Pesticide Toxicity
Additional Keywords : Bird Population Decline
Problem Substances : Chlorpyrifos, Pesticides
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Impaired innate and conditioned social behavior in adult C57Bl6/J mice prenatally exposed to chlorpyrifos.Feb 28, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Behav Brain Funct. 2019 Mar 1 ;15(1):2. Epub 2019 Mar 1. PMID: 30823929
Article Published Date : Feb 28, 2019
Study Type : Animal Study
Additional Links
Diseases : Neurodevelopmental Disorders, Pesticide Toxicity , Prenatal Chemical Exposures
Problem Substances : Chlorpyrifos
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Low doses of chlorpyrifos interfere with spermatogenesis of rats.Jul 17, 2017

Pubmed Data : Environ Sci Pollut Res Int. 2017 Jul 18. Epub 2017 Jul 18. PMID: 28721614
Article Published Date : Jul 17, 2017
Study Type : Animal Study
Additional Links
Diseases : Infertility: Male, Pesticide Toxicity
Problem Substances : Chlorpyrifos, Pesticides
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Modulatory effect of papaya extract against chlorpyrifos-induced oxidative stress, immune suppression, endocrine disruption, and DNA damage.Jan 11, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Environ Res Public Health. 2022 04 12 ;19(8). Epub 2022 Apr 12. PMID: 35457505
Article Published Date : Jan 11, 2022
Study Type : Animal Study
Additional Links
Substances : Papaya
Diseases : DNA damage, Oxidative Stress, Pesticide Toxicity
Pharmacological Actions : Antioxidants, Hepatoprotective, Renoprotective
Additional Keywords : Plant Extracts
Problem Substances : Chlorpyrifos, Pesticides
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NAC may significantly ameliorate chlorpyrifos-induced damages to spermatogonia, spermatocytes, spermatids cell counts and sperm parameters.Mar 31, 2019

Pubmed Data : Int J Fertil Steril. 2019 Apr ;13(1):51-56. Epub 2019 Jan 6. PMID: 30644245
Article Published Date : Mar 31, 2019
Study Type : Animal Study
Additional Links
Substances : NAC (N-acetyl-L-cysteine)
Diseases : Pesticide Toxicity , Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Cytoprotective
Problem Substances : Chlorpyrifos
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Nephroprotective role of Beta vulgaris L. root extract against chlorpyrifos-induced renal injury in rats.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2019 ;2019:3595761. Epub 2019 Nov 22. PMID: 31885644
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Beet
Diseases : Kidney Damage: Chemically-Induced, Pesticide Toxicity
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
Problem Substances : Chlorpyrifos
[+]

Neuroprotective efficacy of berberine following developmental exposure to chlorpyrifos in F1 generation of Wistar rats.Apr 15, 2022

Pubmed Data : Sci Total Environ. 2022 Apr 16 ;834:155292. Epub 2022 Apr 16. PMID: 35439518
Article Published Date : Apr 15, 2022
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Pesticide Toxicity
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents
Problem Substances : Chlorpyrifos
[+]

New insights into baicalein's effect on chlorpyrifos-induced liver injury.Mar 07, 2023

Pubmed Data : J Agric Food Chem. 2023 Mar 8 ;71(9):4132-4143. Epub 2023 Feb 27. PMID: 36848483
Article Published Date : Mar 07, 2023
Study Type : Animal Study
Additional Links
Substances : Baicalein
Diseases : Chemically-Induced Liver Damage
Pharmacological Actions : Hepatoprotective
Problem Substances : Chlorpyrifos, Pesticides
[+]

Olive leaf extract attenuates chlorpyrifos-induced neuro-and reproductive toxicity.Sep 26, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Life (Basel). 2022 Sep 27 ;12(10). Epub 2022 Sep 27. PMID: 36294935
Article Published Date : Sep 26, 2022
Study Type : Animal Study
Additional Links
Substances : Olive leaf extract
Diseases : Pesticide Toxicity
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Problem Substances : Chlorpyrifos
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Oral intake of hydrogen-rich water ameliorated chlorpyrifos-induced neurotoxicity in rats.Sep 30, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Toxicol Appl Pharmacol. 2014 Oct 1 ;280(1):169-76. Epub 2014 Jun 24. PMID: 24967689
Article Published Date : Sep 30, 2014
Study Type : Animal Study
Additional Links
Substances : Hydrogen Water
Diseases : Pesticide Toxicity
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Chlorpyrifos
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Potential role of N-acetylcysteine on chlorpyrifos-induced neurotoxicity in rats.May 17, 2019

Pubmed Data : Environ Sci Pollut Res Int. 2019 May 18. Epub 2019 May 18. PMID: 31104238
Article Published Date : May 17, 2019
Study Type : Animal Study
Additional Links
Substances : NAC (N-acetyl-L-cysteine)
Diseases : Pesticide Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Chlorpyrifos
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Propolis relieves the cardiotoxicity of chlorpyrifos in diabetic rats.Aug 31, 2019

Pubmed Data : Pestic Biochem Physiol. 2019 Sep ;159:127-135. Epub 2019 Jun 12. PMID: 31400774
Article Published Date : Aug 31, 2019
Study Type : Animal Study
Additional Links
Substances : Bee Propolis
Diseases : Pesticide Toxicity
Pharmacological Actions : Antioxidants, Cardioprotective, Paraoxonase down-regulation, Xanthine oxidase inhibitor
Problem Substances : Chlorpyrifos
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Protective effect of chrysin against chlorpyrifos-induced hepatotoxicity.Oct 24, 2022

Pubmed Data : Curr Pharm Biotechnol. 2022 Oct 25. Epub 2022 Oct 25. PMID: 36284384
Article Published Date : Oct 24, 2022
Study Type : Animal Study
Additional Links
Substances : Chrysin
Diseases : Chemically-Induced Liver Damage, Pesticide Toxicity
Pharmacological Actions : Hepatoprotective
Problem Substances : Chlorpyrifos
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Protective effect of chrysin against chlorpyrifos-induced metabolic impairment and pancreatitis.Feb 19, 2023

Pubmed Data : Curr Mol Pharmacol. 2023 Feb 20. Epub 2023 Feb 20. PMID: 36825695
Article Published Date : Feb 19, 2023
Study Type : Animal Study
Additional Links
Substances : Chrysin
Diseases : Pancreatitis, Pesticide Toxicity
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation, Pancreato Protective Agents
Problem Substances : Chlorpyrifos
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Protective effects of chrysin on hippocampal damage induced by chlorpyrifos.Mar 01, 2023

Pubmed Data : Curr Drug Discov Technol. 2023 Mar 2. Epub 2023 Mar 2. PMID: 36861795
Article Published Date : Mar 01, 2023
Study Type : Animal Study
Additional Links
Substances : Chrysin
Diseases : Pesticide Toxicity
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Chlorpyrifos
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Protective effects of molecular hydrogen on hepatotoxicity induced by sub-chronic exposure to chlorpyrifos.Sep 10, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ann Agric Environ Med. 2020 Sep 11 ;27(3):368-373. Epub 2020 Aug 11. PMID: 32955216
Article Published Date : Sep 10, 2020
Study Type : Animal Study
Additional Links
Substances : Hydrogen Water
Diseases : Chemically-Induced Liver Damage, Oxidative Stress
Pharmacological Actions : Antioxidants, Hepatoprotective
Problem Substances : Chlorpyrifos
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Quercetin plays protective role in oxidative induced apoptotic events during chronic chlorpyrifos exposure to rats.Apr 15, 2019

Pubmed Data : J Biochem Mol Toxicol. 2019 Apr 16:e22341. Epub 2019 Apr 16. PMID: 30990955
Article Published Date : Apr 15, 2019
Study Type : Animal Study
Additional Links
Substances : Quercetin
Diseases : Pesticide Toxicity
Pharmacological Actions : Anti-Apoptotic, Antioxidants
Problem Substances : Chlorpyrifos
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Red beetroot could be used as a potential therapeutic intervention to minimize chlorpyrifos hepatotoxicity.Jul 06, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomolecules. 2019 Jul 7 ;9(7). Epub 2019 Jul 7. PMID: 31284640
Article Published Date : Jul 06, 2019
Study Type : Animal Study
Additional Links
Substances : Beet
Diseases : Chemically-Induced Liver Damage, Pesticide Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective, Nrf2 activation
Problem Substances : Chlorpyrifos
[+]

Red beetroot extract abrogates chlorpyrifos-induced cortical damage.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2020 ;2020:2963020. Epub 2020 Mar 9. PMID: 32215171
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Beet
Diseases : Pesticide Toxicity
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
Problem Substances : Chlorpyrifos
[+]

Red beetroot extract could help prevent chlorpyrifos-induced testicular damage via antioxidant, anti-inflammatory, and anti-apoptotic pathways.Dec 09, 2019

Pubmed Data : Environ Sci Pollut Res Int. 2019 Dec 10. Epub 2019 Dec 10. PMID: 31823260
Article Published Date : Dec 09, 2019
Study Type : Animal Study
Additional Links
Substances : Beet
Diseases : Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants
Problem Substances : Chlorpyrifos
[+]

Rosmarinic acid mitigates chlorpyrifos-induced oxidative stress, inflammation, and kidney injury.Jan 14, 2023

Pubmed Data : Life Sci. 2023 Jan 15 ;313:121281. Epub 2022 Dec 12. PMID: 36521549
Article Published Date : Jan 14, 2023
Study Type : Animal Study
Additional Links
Substances : Rosemaric Acid
Diseases : Inflammation, Kidney Damage: Chemically-Induced, Oxidative Stress, Pesticide Toxicity
Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Interleukin-1 beta downregulation, NF-kappaB Inhibitor, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Chlorpyrifos
[+]

Selenium is an antioxidant that reduces the toxic effects caused by chlorpyrifos.Feb 09, 2021

Pubmed Data : Biol Trace Elem Res. 2021 Feb 10. Epub 2021 Feb 10. PMID: 33566284
Article Published Date : Feb 09, 2021
Study Type : Animal Study
Additional Links
Substances : Selenium
Diseases : Pesticide Toxicity
Pharmacological Actions : Antioxidants
Problem Substances : Chlorpyrifos
[+]

Single and joint effects of chronic exposure to chlorpyrifos and glyphosate based pesticides on structural biomarkers in Cnesterodon decemmaculatus.Jul 08, 2019

Pubmed Data : Chemosphere. 2019 Jul 9 ;236:124311. Epub 2019 Jul 9. PMID: 31310974
Article Published Date : Jul 08, 2019
Study Type : Animal Study
Additional Links
Diseases : Glyphosate Toxicity, Pesticide Toxicity
Additional Keywords : Toxic Substance Synergy
Problem Substances : Chlorpyrifos, Glyphosate
[+]

Spirulina platensis reduced oxidative damage induced by chlorpyrifos toxicity in nile tilapia.Mar 11, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Animals (Basel). 2020 Mar 12 ;10(3). Epub 2020 Mar 12. PMID: 32178251
Article Published Date : Mar 11, 2020
Study Type : Animal Study
Additional Links
Substances : Spirulina
Diseases : Oxidative Stress, Pesticide Toxicity
Pharmacological Actions : Antioxidants
Problem Substances : Chlorpyrifos
[+]

sublethal concentrations of the chlorpyrifos pesticide may affect the fitness and survival of the larvae of R. arenarum.Dec 06, 2018

Pubmed Data : Chemosphere. 2018 Dec 7 ;219:671-677. Epub 2018 Dec 7. PMID: 30557723
Article Published Date : Dec 06, 2018
Study Type : Animal Study
Additional Links
Diseases : Pesticide Toxicity
Problem Substances : Chlorpyrifos
[+]

Synergic effects of aerobic exercise and eugenol supplement on germ cell development and testicular tissue structure in chlorpyrifos-treated animal model.Mar 08, 2020

Pubmed Data : Environ Sci Pollut Res Int. 2020 Mar 9. Epub 2020 Mar 9. PMID: 32152857
Article Published Date : Mar 08, 2020
Study Type : Animal Study
Additional Links
Substances : Eugenol
Diseases : Infertility: Male, Pesticide Toxicity , Testicular Injury: Chemical/Metal Induced
Therapeutic Actions : Exercise: Aerobic
Pharmacological Actions : Cytoprotective
Problem Substances : Chlorpyrifos
[+]

Taurine may be useful for prophylaxis against disruptions in thyroid function in animals that are exposed to environmental chlorpyrifos and lead.Aug 24, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Vet Res Commun. 2016 Aug 25. Epub 2016 Aug 25. PMID: 27562511
Article Published Date : Aug 24, 2016
Study Type : Animal Study
Additional Links
Substances : Taurine
Diseases : Thyroid Diseases
Pharmacological Actions : Cytoprotective, Prophylactic Agents
Problem Substances : Chlorpyrifos, Lead
[+]

The study concludes that crocin can alleviate the toxic effect of chlorpyrifos caused by oxidative stress on cardiac muscle.Apr 30, 2019

Pubmed Data : Acta Histochem. 2019 May ;121(4):472-483. Epub 2019 Apr 9. PMID: 30975443
Article Published Date : Apr 30, 2019
Study Type : Animal Study
Additional Links
Substances : Crocin, Saffron
Diseases : Pesticide Toxicity
Pharmacological Actions : Antioxidants, Cardioprotective
Problem Substances : Chlorpyrifos
[+]

These findings indicate that chlorpyrifos has adverse effects on sperm cells and reproductive system of male rats.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Vet Res Forum. 2017 ;8(4):319-326. Epub 2017 Dec 15. PMID: 29326791
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Diseases : Infertility: Male, Pesticide Toxicity
Problem Substances : Chlorpyrifos, Organophosphate Pesticides
[+]

These results suggest that dietary exposure to chlorpyrifos aggravated tissue injuries in mice with DSS-induced chronic colitis.Dec 31, 2019

Pubmed Data : Arch Toxicol. 2020 01 ;94(1):141-150. Epub 2019 Dec 5. PMID: 31807802
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Diseases : Inflammatory Bowel Diseases, Pesticide Toxicity
Problem Substances : Chlorpyrifos
Adverse Pharmacological Actions : Immunosuppressive
[+]

This data provides a molecular basis for observed adverse effects of insecticides to bees.Apr 08, 2017

Pubmed Data : Environ Pollut. 2017 Apr 9 ;226:48-59. Epub 2017 Apr 9. PMID: 28402838
Article Published Date : Apr 08, 2017
Study Type : Insect Study
Additional Links
Diseases : Pesticide Toxicity
Additional Keywords : Gene Expression, Honeybee
Problem Substances : Chlorpyrifos, Organophosphate Pesticides, Pesticides
[+]

This paper highlights the potential use of lactic acid bacteria for the detoxification and removal of chlorpyrifos residues in the environment.Feb 05, 2016

Pubmed Data : J Environ Sci Health B. 2016 Feb 6:1-10. Epub 2016 Feb 6. PMID: 26852781
Article Published Date : Feb 05, 2016
Study Type : Environmental, Plant Study
Additional Links
Substances : Lactobacillus casei
Diseases : Pesticide Toxicity
Pharmacological Actions : Detoxifier
Problem Substances : Chlorpyrifos
[+]

Vitamin C ameliorates alterations in thyroid hormones concentrations induced by subchronic coadministration of chlorpyrifos and lead in wistar rats.Jan 01, 2011

Pubmed Data : J Thyroid Res. 2011;2011:214924. Epub 2011 May 23. PMID: 21687644
Article Published Date : Jan 01, 2011
Study Type : Animal Study
Additional Links
Substances : Vitamin C
Diseases : Hypothyroidism, Lead Poisoning, Pesticide-Induced Toxicity: Organophosphates
Problem Substances : Chlorpyrifos, Lead, Organophosphates, Pesticides
[+]

Vitamin C pretreatment ameliorated the chronic chlorpyrifos induced hemotoxicity in wistar rats.Dec 31, 2010

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Vet Med Int. 2011 ;2011:945439. Epub 2011 Apr 27. PMID: 21647348
Article Published Date : Dec 31, 2010
Study Type : Animal Study
Additional Links
Substances : Vitamin C
Diseases : Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
Problem Substances : Chlorpyrifos
[+]

Antioxidative and immunoprotective potential of chlorella vulgaris dietary supplementation against chlorpyrifos-induced toxicity.May 17, 2020

Pubmed Data : Fish Physiol Biochem. 2020 May 18. Epub 2020 May 18. PMID: 32424629
Article Published Date : May 17, 2020
Study Type : In Vitro Study
Additional Links
Substances : Chlorella (Algae)
Diseases : Pesticide Toxicity
Pharmacological Actions : Antioxidants, Immunomodulatory
Problem Substances : Chlorpyrifos
[+]

Berberine affords protection against oxidative stress and apoptotic damage in F1 generation of wistar rats following lactational exposure to chlorpyrifos.Oct 31, 2021

Pubmed Data : Pestic Biochem Physiol. 2021 Nov ;179:104977. Epub 2021 Oct 11. PMID: 34802527
Article Published Date : Oct 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Berberine
Diseases : Oxidative Stress, Pesticide Toxicity
Pharmacological Actions : Anti-Apoptotic, Antioxidants
Problem Substances : Chlorpyrifos
[+]

Betulinic acid protects against cardiotoxicity of the organophosphorus pesticide chlorpyrifos.Mar 31, 2023

Pubmed Data : Environ Sci Pollut Res Int. 2023 Apr ;30(17):51180-51190. Epub 2023 Feb 20. PMID: 36808036
Article Published Date : Mar 31, 2023
Study Type : In Vitro Study
Additional Links
Substances : Betulinic acid
Diseases : Inflammation, Oxidative Stress, Pesticide Toxicity
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Cardioprotective, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Chlorpyrifos, Pesticides
[+]

Chlorpyrifos activates cell pyroptosis and increases susceptibility on oxidative stress-induced toxicity.May 31, 2019

Pubmed Data : Environ Toxicol. 2019 Jun ;34(6):699-707. Epub 2019 Mar 5. PMID: 30835941
Article Published Date : May 31, 2019
Study Type : In Vitro Study
Additional Links
Diseases : Brain: Oxidative Stress, Parkinson's Disease, Pesticide Toxicity
Pharmacological Actions : Antioxidants, Neuroprotective Agents, Nrf2 activation
Problem Substances : Chlorpyrifos
[+]

Chlorpyrifos can decrease the viability of adipose tissue-derived stem cells-derived neurons and dysregulate the expression of some neuronal markers.Oct 31, 2016

Pubmed Data : Environ Toxicol. 2016 Nov ;31(11):1510-1519. Epub 2015 May 27. PMID: 26018426
Article Published Date : Oct 31, 2016
Study Type : In Vitro Study
Additional Links
Diseases : Neurodegenerative Diseases, Pesticide Toxicity
Additional Keywords : Chlorpyrifos, Neurodegenerative diseases, Pesticide Toxicity
Problem Substances : Chlorpyrifos
[+]

Chlorpyrifos may affect neurodevelopment in a manner similar to that of several known and suspected neurotoxicants.Apr 30, 2014

Pubmed Data : Neurotoxicology. 2014 May ;42:58-70. Epub 2014 Apr 12. PMID: 24727577
Article Published Date : Apr 30, 2014
Study Type : In Vitro Study
Additional Links
Diseases : Oxidative Stress, Pesticide Toxicity
Additional Keywords : Chlorpyrifos, oxidative stress, Pesticide Toxicity
Problem Substances : Chlorpyrifos
[+]

Developmental neurotoxicity of the organophosphorus insecticide chlorpyrifos.Jul 31, 2017

Pubmed Data : J Neurochem. 2017 Aug ;142 Suppl 2:162-177. PMID: 28791702
Article Published Date : Jul 31, 2017
Study Type : Review
Additional Links
Diseases : Pesticide Toxicity
Additional Keywords : Chlorpyrifos, Pesticide Toxicity
Problem Substances : Chlorpyrifos
Adverse Pharmacological Actions : Neurotoxic
[+]

Extracts of Ilex paraguariensis protected splenocytes in vitro against chlorpyrifos.Jan 20, 2017

Pubmed Data : Rev Fac Cien Med Univ Nac Cordoba. 2017 12 21 ;74(4):325-330. Epub 2017 Dec 21. PMID: 29902138
Article Published Date : Jan 20, 2017
Study Type : In Vitro Study
Additional Links
Substances : Yerba Mate
Diseases : Pesticide Toxicity
Pharmacological Actions : Anti-Apoptotic
Additional Keywords : Plant Extracts
Problem Substances : Chlorpyrifos
[+]

Pinocembrin pretreatment counteracts the chlorpyrifos-induced HO-1 downregulation, mitochondrial dysfunction, and inflammation in the SH-SY5Y cells.Nov 30, 2021

Pubmed Data : Metab Brain Dis. 2021 Dec ;36(8):2377-2391. Epub 2021 Aug 2. PMID: 34338973
Article Published Date : Nov 30, 2021
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids
Diseases : Mitochondrial Dysfunction , Pesticide Toxicity
Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Nrf2 activation
Problem Substances : Chlorpyrifos
[+]

Pterostilbene alleviates chlorpyrifos-induced damage during porcine oocyte maturation.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Cell Dev Biol. 2021 ;9:803181. Epub 2021 Dec 21. PMID: 34993205
Article Published Date : Dec 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Pterostilbene
Diseases : Pesticide Toxicity
Pharmacological Actions : Anti-Apoptotic
Problem Substances : Chlorpyrifos
[+]

Sub-toxic chlorpyrifos exposure induces oxidative stress in muscle cells activating redox sensitive kinases.Nov 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Diabetes Metab Disord. 2018 Dec ;17(2):325-332. Epub 2018 Nov 28. PMID: 30918868
Article Published Date : Nov 30, 2018
Study Type : In Vitro Study
Additional Links
Diseases : Oxidative Stress, Pesticide Toxicity
Problem Substances : Chlorpyrifos
[+]

These results provide new understanding of the mechanisms contributing to the harmful effects of chlorpyrifos.Apr 13, 2018

Pubmed Data : Toxicology. 2018 Apr 14 ;402-403:17-27. Epub 2018 Apr 14. PMID: 29665406
Article Published Date : Apr 13, 2018
Study Type : In Vitro Study
Additional Links
Diseases : Neurodegenerative Diseases, Pesticide Toxicity
Problem Substances : Chlorpyrifos
[+]

These two pesticides in mixtures were verified to act together in a synergistic manner under experimental conditions.Jul 14, 2017

Pubmed Data : J Hazard Mater. 2017 Jul 15 ;334:121-131. Epub 2017 Mar 27. PMID: 28407539
Article Published Date : Jul 14, 2017
Study Type : In Vitro Study
Additional Links
Diseases : Oxidative Stress, Pesticide Toxicity
Additional Keywords : Synergistic Toxicity
Problem Substances : Chlorpyrifos, Cypermethrin, Pesticides
[+]

UV-C light irradiation enhances toxic effects of chlorpyrifos and its formulations.Jan 14, 2019

Pubmed Data : Food Chem. 2019 Jan 15 ;271:469-478. Epub 2018 Jul 31. PMID: 30236704
Article Published Date : Jan 14, 2019
Study Type : In Vitro Study
Additional Links
Diseases : Pesticide Toxicity
Additional Keywords : Increased Risk, Pesticide Residue In Foods, Ultraviolet C
Problem Substances : Chlorpyrifos, Pesticides

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