Dichloro-diphenyl-trichloroethane (DDT)

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21 Diseases Researched for Dichloro-diphenyl-trichloroethane (DDT)
NameACCKFocus
Pesticide Toxicity 18107Locked
Breast Cancer982Locked
Prenatal Chemical Exposures432Locked
Hypothyroidism220Locked
Pregnancy: Environmental Exposures220Locked
Pesticide-Induced Toxicity: Organochlorines212Locked
Bladder Cancer110Locked
Breastfeeding Concerns: Chemical Exposure110Locked
Multiple Myeloma110Locked
Chemically-Induced Liver Damage48Locked
Obesity36Locked
Chronic Kidney Disease (CKD)12Locked
Diabetes Mellitus: Type 212Locked
Fetal Origin of Adult Disease12Locked
Infertility: Male12Locked
Inflammation12Locked
Autism Spectrum Disorders11Locked
Colorectal Cancer11Locked
Mitochondrial Dysfunction 11Locked
Oxidative Stress11Locked
Polio11Locked
4 Adverse Pharmacological Actions Researched for Dichloro-diphenyl-trichloroethane (DDT)
NameACCKFocus
Carcinogenic440Locked
Bioaccumulator110Locked
Inflammatory12Locked
Diabetogenic11Locked

View the Evidence:
35 Abstracts with Dichloro-diphenyl-trichloroethane (DDT) Research

[+]

Breast cancer patients have higher serum organochlorine residues, indicating that it may contribute to carcinogenesis.May 01, 2003

Pubmed Data : Occup Environ Med. 2003 May;60(5):348-51. PMID: 12709520
Article Published Date : May 01, 2003
Study Type : Human Study
Additional Links
Diseases : Breast Cancer
Problem Substances : Dichloro-diphenyl-trichloroethane (DDT) , Hexachlorobenzene (HCB)
Adverse Pharmacological Actions : Carcinogenic
[+]

DDE exposure at low concentrations could disrupt thyroid homeostasis during pregnancy.Jun 30, 2017

Pubmed Data : Environ Res. 2017 Jul ;156:597-604. Epub 2017 Apr 26. PMID: 28448812
Article Published Date : Jun 30, 2017
Study Type : Human Study
Additional Links
Diseases : Pesticide Toxicity , Prenatal Chemical Exposures
Problem Substances : Dichloro-diphenyl-trichloroethane (DDT)
[+]

DDT exposure in early childhood could raise the risk of breast cancer in adulthood.Jan 11, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Int. 2018 12 ;121(Pt 2):1106-1112. Epub 2018 Oct 28. PMID: 30376997
Article Published Date : Jan 11, 2018
Study Type : Human Study
Additional Links
Diseases : Breast Cancer, Pesticide Toxicity
Additional Keywords : Increased Risk
Problem Substances : Dichloro-diphenyl-trichloroethane (DDT)
[+]

DDT was associated with breast cancer through age 54 years.Feb 12, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Natl Cancer Inst. 2019 Feb 13. Epub 2019 Feb 13. PMID: 30759253
Article Published Date : Feb 12, 2019
Study Type : Human Study
Additional Links
Diseases : Breast Cancer, Pesticide Toxicity
Additional Keywords : Increased Risk
Problem Substances : Dichloro-diphenyl-trichloroethane (DDT) , Endocrine Disrupting Chemicals (EDCs)
[+]

DTT exposure is associated with increased breast cancer risk.Jan 01, 2010

Pubmed Data : Asian Pac J Cancer Prev. 2010;11(1):173-80. PMID: 20593953
Article Published Date : Jan 01, 2010
Study Type : Human Study
Additional Links
Diseases : Breast Cancer
Problem Substances : Dichloro-diphenyl-trichloroethane (DDT) , Organochlorine pesticides, Pesticides
Adverse Pharmacological Actions : Carcinogenic
[+]

Early prenatal exposure to DDT may affect fetal BRCA1 gene methylation.Apr 30, 2018

Pubmed Data : Life Sci. 2018 May 1 ;200:81-86. Epub 2018 Mar 15. PMID: 29551577
Article Published Date : Apr 30, 2018
Study Type : Human Study
Additional Links
Diseases : Pesticide Toxicity , Prenatal Chemical Exposures
Additional Keywords : DNA Methylation
Problem Substances : Dichloro-diphenyl-trichloroethane (DDT)
[+]

Effects of exposure to polychlorinated biphenyls and organochlorine pesticides have an adverse effect on thyroid function during pregnancy.Aug 01, 2008

Pubmed Data : Am J Epidemiol. 2008 Aug 1;168(3):298-310. Epub 2008 Jun 10. PMID: 18550560
Article Published Date : Aug 01, 2008
Study Type : Human Study
Additional Links
Diseases : Hypothyroidism, Pregnancy: Environmental Exposures
Problem Substances : Dichloro-diphenyl-trichloroethane (DDT) , Polychlorinated biphenyls (PCBs)
[+]

Exposure to DDE/DDT may adversely impact overall and breast cancer-specific survival.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Int. 2019 04 ;125:161-171. Epub 2019 Feb 1. PMID: 30716576
Article Published Date : Dec 31, 2018
Study Type : Human Study
Additional Links
Diseases : Breast Cancer, Pesticide Toxicity
Additional Keywords : Increased Risk
Problem Substances : Dichloro-diphenyl-trichloroethane (DDT) , Dichlorodiphenyldichloroethylene (DDE), Pesticides
[+]

Exposure to organochloride compounds alter thyroid hormone levels during pregnancy. Oct 15, 2009

Pubmed Data : Environ Sci Technol. 2009 Oct 15;43(20):7909-15. PMID: 19921913
Article Published Date : Oct 15, 2009
Study Type : Human Study
Additional Links
Diseases : Hypothyroidism, Pregnancy: Environmental Exposures
Problem Substances : Dichloro-diphenyl-trichloroethane (DDT) , Hexachlorobenzene (HCB), Organochlorine compounds, Organochlorine pesticides, Pesticides, Polychlorinated biphenyls (PCBs)
[+]

Exposure to organochlorine pesticides is an independent risk factor of hepatocellular carcinoma.Sep 14, 2011

Pubmed Data : J Expo Sci Environ Epidemiol. 2011 Sep 14. Epub 2011 Sep 14. PMID: 21915153
Article Published Date : Sep 14, 2011
Study Type : Human Study
Additional Links
Diseases : Pesticide-Induced Toxicity: Organochlorines
Problem Substances : Dichloro-diphenyl-trichloroethane (DDT) , Organochlorine pesticides
Adverse Pharmacological Actions : Carcinogenic
[+]

In utero DDT exposure and breast density before age 50.Nov 07, 2019

Pubmed Data : Reprod Toxicol. 2019 Nov 8. Epub 2019 Nov 8. PMID: 31711904
Article Published Date : Nov 07, 2019
Study Type : Human Study
Additional Links
Diseases : Pesticide Toxicity
Problem Substances : Dichloro-diphenyl-trichloroethane (DDT)
[+]

Non-occupational rganochlorine pesticide exposure is associated with increased risk of breast cancer. Jul 01, 2006

Pubmed Data : Wei Sheng Yan Jiu. 2006 Jul;35(4):391-4. PMID: 16986505
Article Published Date : Jul 01, 2006
Study Type : Human Study
Additional Links
Diseases : Breast Cancer
Problem Substances : Dichloro-diphenyl-trichloroethane (DDT) , Hexachlorocyclohexane
Adverse Pharmacological Actions : Carcinogenic
[+]

Organochlorine and organophosphorus pesticides and bladder cancer.Aug 31, 2019

Pubmed Data : J Cell Biochem. 2019 Sep ;120(9):14847-14859. Epub 2019 Apr 22. PMID: 31009110
Article Published Date : Aug 31, 2019
Study Type : Human Study
Additional Links
Diseases : Bladder Cancer, Pesticide Toxicity
Additional Keywords : Increased Risk
Problem Substances : Dichloro-diphenyl-trichloroethane (DDT) , Organochlorine pesticides, Pesticides
[+]

Persistent organochlorine pesticides are commonly found in breast milk samples from women in mainland China. Feb 01, 2011

Pubmed Data : Environ Pollut. 2011 Feb;159(2):524-31. Epub 2010 Nov 19. PMID: 21093969
Article Published Date : Feb 01, 2011
Study Type : Human Study
Additional Links
Diseases : Breastfeeding Concerns: Chemical Exposure
Additional Keywords : Meat-Pesticide Accumulation
Problem Substances : Dichloro-diphenyl-trichloroethane (DDT) , Organochlorine pesticides, Pesticides
Adverse Pharmacological Actions : Bioaccumulator
[+]

Serum levels of organochlorine pesticides and breast cancer risk in Iranian women.Oct 31, 2019

Pubmed Data : Arch Environ Contam Toxicol. 2019 Nov ;77(4):480-489. Epub 2019 Jul 19. PMID: 31324944
Article Published Date : Oct 31, 2019
Study Type : Human Study
Additional Links
Diseases : Breast Cancer, Pesticide Toxicity
Additional Keywords : Increased Risk
Problem Substances : Dichloro-diphenyl-trichloroethane (DDT) , Dichlorodiphenyldichloroethylene (DDE)
[+]

These findings suggest prenatal DDT exposure may have life-long consequence through alteration in genes relevant to breast cancer.Feb 25, 2019

Pubmed Data : Reprod Toxicol. 2019 Feb 26. Epub 2019 Feb 26. PMID: 30822522
Article Published Date : Feb 25, 2019
Study Type : Human Study
Additional Links
Diseases : Breast Cancer, Pesticide Toxicity , Prenatal Chemical Exposures
Additional Keywords : Increased Risk
Problem Substances : Dichloro-diphenyl-trichloroethane (DDT)
[+]

This study observed significant increases in Multiple myeloma risk for use of carbaryl, captan and DDT.Oct 14, 2016

Pubmed Data : Int J Cancer. 2016 Oct 15 ;139(8):1703-14. Epub 2016 Jun 28. PMID: 27261772
Article Published Date : Oct 14, 2016
Study Type : Human Study
Additional Links
Diseases : Multiple Myeloma
Additional Keywords : Increased Risk
Problem Substances : Dichloro-diphenyl-trichloroethane (DDT) , Pesticides
[+]

Vitamin C intervention may have important public health implications in protecting health by reducing body burdens of POPs.Apr 14, 2016

Pubmed Data : Food Chem Toxicol. 2016 Apr 15. Epub 2016 Apr 15. PMID: 27090108
Article Published Date : Apr 14, 2016
Study Type : Human Study
Additional Links
Substances : Vitamin C
Problem Substances : Dichloro-diphenyl-trichloroethane (DDT) , Dichlorodiphenyldichloroethylene (DDE), Organochlorine pesticides, Persistent organic pollutants (POPs), Polychlorinated biphenyls (PCBs)
[+]

Ancestral dichlorodiphenyltrichloroethane (DDT) exposure promotes epigenetic transgenerational inheritance of obesity.Oct 22, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Med. 2013 Oct 23 ;11:228. Epub 2013 Oct 23. PMID: 24228800
Article Published Date : Oct 22, 2013
Study Type : Animal Study
Additional Links
Diseases : Fetal Origin of Adult Disease, Obesity, Prenatal Chemical Exposures
Additional Keywords : Increased Risk, Transgenerational inheritance
Problem Substances : Dichloro-diphenyl-trichloroethane (DDT)
[+]

Ancestral p,p'-DDE exposure could induce transgenerational pancreatic impairment with Igf2/H19 epigenetic defect.Oct 04, 2017

Pubmed Data : Toxicol Lett. 2017 Oct 5 ;280:222-231. Epub 2017 Sep 1. PMID: 28867213
Article Published Date : Oct 04, 2017
Study Type : Animal Study
Additional Links
Diseases : Infertility: Male
Additional Keywords : Transgenerational Epigenetic Modification
Problem Substances : Dichloro-diphenyl-trichloroethane (DDT)
[+]

Both pentachlorophenol and DDT have the potential to produce chronic inflammation.Oct 31, 2019

Pubmed Data : Environ Toxicol Pharmacol. 2019 Nov ;72:103263. Epub 2019 Sep 12. PMID: 31542660
Article Published Date : Oct 31, 2019
Study Type : Animal Study
Additional Links
Diseases : Inflammation, Pesticide-Induced Toxicity: Organochlorines, Pesticide Toxicity
Problem Substances : Dichloro-diphenyl-trichloroethane (DDT) , Organochlorine pesticides
Adverse Pharmacological Actions : Inflammatory
[+]

DDE exposure at concentrations relevant to human exposure accelerates mammary carcinogenesis in mice.Jul 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Health Perspect. 2012 Aug ;120(8):1170-6. Epub 2012 Apr 18. PMID: 22514210
Article Published Date : Jul 31, 2012
Study Type : Animal Study
Additional Links
Diseases : Breast Cancer, Pesticide Toxicity
Problem Substances : Dichloro-diphenyl-trichloroethane (DDT) , Dichlorodiphenyldichloroethylene (DDE)
[+]

Developmental origins of transgenerational sperm DNA methylation epimutations following ancestral DDT exposure.Jan 14, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Dev Biol. 2019 01 15 ;445(2):280-293. Epub 2018 Nov 27. PMID: 30500333
Article Published Date : Jan 14, 2019
Study Type : Animal Study
Additional Links
Diseases : Pesticide Toxicity
Additional Keywords : DNA Methylation, Transgenerational Epigenetic Modification
Problem Substances : Dichloro-diphenyl-trichloroethane (DDT) , Pesticides
[+]

Dichlorodiphenyltrichloroethane technical mixture regulates cell cycle and apoptosis genes through the activation of CAR and ERα in mouse livers.Aug 31, 2013

Pubmed Data : Toxicol Appl Pharmacol. 2013 Sep 1 ;271(2):137-43. Epub 2013 May 14. PMID: 23684557
Article Published Date : Aug 31, 2013
Study Type : Animal Study
Additional Links
Diseases : Chemically-Induced Liver Damage, Pesticide Toxicity
Problem Substances : Dichloro-diphenyl-trichloroethane (DDT)
[+]

Excessive pesticide use in the Sebitoli area may contribute to facial dysplasia in chimpanzees and baboons.Apr 24, 2017

Pubmed Data : Sci Total Environ. 2017 Apr 25 ;598:647-656. Epub 2017 Apr 25. PMID: 28454037
Article Published Date : Apr 24, 2017
Study Type : Animal Study
Additional Links
Diseases : Pesticide Toxicity
Problem Substances : Chlorpyrifos, Cypermethrin, Dichloro-diphenyl-trichloroethane (DDT) , Glyphosate, Pesticides
[+]

REDOX proteomics reveals energy metabolism alterations in the liver of M. spretus mice exposed to p, p'-DDE.Oct 31, 2017

Pubmed Data : Chemosphere. 2017 Nov ;186:848-863. Epub 2017 Aug 13. PMID: 28826133
Article Published Date : Oct 31, 2017
Study Type : Animal Study
Additional Links
Diseases : Chemically-Induced Liver Damage
Problem Substances : Dichloro-diphenyl-trichloroethane (DDT) , Pesticides
[+]

Sperm epimutation biomarkers of obesity and pathologies following DDT induced epigenetic transgenerational inheritance of disease.Mar 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Epigenet. 2019 Apr ;5(2):dvz008. Epub 2019 May 27. PMID: 31186947
Article Published Date : Mar 31, 2019
Study Type : Animal Study
Additional Links
Diseases : Chronic Kidney Disease (CKD), Obesity, Pesticide Toxicity
Additional Keywords : Increased Risk, Transgenerational Epigenetic Modification
Problem Substances : Dichloro-diphenyl-trichloroethane (DDT)
[+]

The effect of acute dichlorodiphenyltrichloroethane exposure on hypermethylation status and down-regulation of p53 and p16INK4a genes in rat liver.Apr 30, 2016

Pubmed Data : Environ Toxicol. 2016 May ;31(5):584-92. Epub 2014 Nov 20. PMID: 25410620
Article Published Date : Apr 30, 2016
Study Type : Animal Study
Additional Links
Diseases : Chemically-Induced Liver Damage, Pesticide Toxicity
Additional Keywords : DNA Methylation
Problem Substances : Dichloro-diphenyl-trichloroethane (DDT)
[+]

Transcriptome signatures of p,p´-DDE-induced liver damage in Mus spretus mice.Jun 30, 2018

Pubmed Data : Environ Pollut. 2018 Jul ;238:150-167. Epub 2018 Mar 20. PMID: 29554563
Article Published Date : Jun 30, 2018
Study Type : Animal Study
Additional Links
Diseases : Chemically-Induced Liver Damage, Diabetes Mellitus: Type 2, Obesity, Pesticide Toxicity
Problem Substances : Dichloro-diphenyl-trichloroethane (DDT) , Dichlorodiphenyldichloroethylene (DDE), Organochlorine pesticides, Pesticides
[+]

Children were sprayed with DDT as part of polio eradication programs.Oct 01, 1995

Pubmed Data : Nat Genet. 1995 Oct ;11(2):105-6. PMID: 7550327
Article Published Date : Oct 01, 1995
Study Type : Commentary
Additional Links
Diseases : Polio
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Dichloro-diphenyl-trichloroethane (DDT)
[+]

Dichlorodiphenyltrichloroethane promotes aerobic glycolysis in colorectal cancer cells.Nov 12, 2019

Pubmed Data : Environ Toxicol. 2019 Nov 13. Epub 2019 Nov 13. PMID: 31724279
Article Published Date : Nov 12, 2019
Study Type : In Vitro Study
Additional Links
Diseases : Colorectal Cancer
Additional Keywords : Increased Risk
Problem Substances : Dichloro-diphenyl-trichloroethane (DDT)
[+]

Exposure to DDT and DDE at sublethal concentrations may influence protein expression in human pancreatic beta cells.Jul 13, 2015

Pubmed Data : Environ Res. 2015 Jul 14 ;142:257-263. Epub 2015 Jul 14. PMID: 26186133
Article Published Date : Jul 13, 2015
Study Type : In Vitro Study
Additional Links
Problem Substances : Dichloro-diphenyl-trichloroethane (DDT) , Dichlorodiphenyldichloroethylene (DDE), Organochlorine compounds
Adverse Pharmacological Actions : Diabetogenic
[+]

Expression of the miR-190 family is increased under DDT exposure in vivo and in vitro.Nov 30, 2018

Pubmed Data : Mol Biol Rep. 2018 Dec ;45(6):1937-1945. Epub 2018 Nov 12. PMID: 30421125
Article Published Date : Nov 30, 2018
Study Type : In Vitro Study
Additional Links
Diseases : Pesticide Toxicity
Problem Substances : Dichloro-diphenyl-trichloroethane (DDT)
[+]

Oxidative phosphorylation impairment by DDT and DDE.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Endocrinol (Lausanne). 2019 ;10:122. Epub 2019 Mar 12. PMID: 30915030
Article Published Date : Dec 31, 2018
Study Type : Review
Additional Links
Diseases : Mitochondrial Dysfunction , Oxidative Stress
Problem Substances : Dichloro-diphenyl-trichloroethane (DDT) , Dichlorodiphenyldichloroethylene (DDE)
[+]

There are evidence supporting the etiological link between exposure to environmental toxicants and the development of autism spectrum disorders.May 01, 2017

Pubmed Data : Environ Pollut. 2017 May 2 ;227:234-242. Epub 2017 May 2. PMID: 28475976
Article Published Date : May 01, 2017
Study Type : Review
Additional Links
Diseases : Autism Spectrum Disorders
Problem Substances : Dichloro-diphenyl-trichloroethane (DDT) , Lead, Mercury, Polychlorinated biphenyls (PCBs)

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