Donepezil (trade name Aricept)

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15 Diseases Researched for Donepezil (trade name Aricept)
NameACCKFocus
Alzheimer's Disease673Locked
Bradycardia343Locked
Dementia324Locked
Diarrhea: Drug-Associated120Locked
Epileptic Seizures120Locked
Seizures120Locked
Cervical Dystonia13Locked
Dementia with Lewy bodies (DLB)13Locked
Liver Failure: Drug Induced13Locked
Alcohol Toxicity 12Locked
Amnesia: Drug-Induced12Locked
Neurodegenerative Diseases12Locked
Parkinson's Disease11Locked
Parkinsonism11Locked
Tremor11Locked
1 Adverse Pharmacological Actions Researched for Donepezil (trade name Aricept)
NameACCKFocus
Neurotoxic323Locked
Related Topics

Donepezil (trade name Aricept) is a Sub of the following Topic

View the Evidence:
10 Abstracts with Donepezil (trade name Aricept) Research

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21 percent of patients who receive donepezil discontinue treatment due to adverse side effects.Dec 07, 2009

Pubmed Data : Ugeskr Laeger. 2009 Dec 7;171(50):3690-3. PMID: 20003864
Article Published Date : Dec 07, 2009
Study Type : Meta Analysis
Additional Links
Diseases : Alzheimer's Disease, Diarrhea: Drug-Associated
Problem Substances : Donepezil (trade name Aricept)
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Cholinesterase inhibitor drug use is associated with increased incidence of bradycardia.Nov 01, 2009

Pubmed Data : J Am Geriatr Soc. 2009 Nov;57(11):1997-2003. Epub 2009 Sep 28. PMID: 19793162
Article Published Date : Nov 01, 2009
Study Type : Meta Analysis
Additional Links
Diseases : Alzheimer's Disease, Bradycardia, Dementia
Problem Substances : Cholinesterase Inhibitor Drugs, Donepezil (trade name Aricept)
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Donepezil and memantine are known to cause bradycardia and to reduce the epileptogenic threshold.May 01, 2010

Pubmed Data : Therapie. 2010 May-Jun;65(3):255-9. Epub 2010 Aug 11. PMID: 20699079
Article Published Date : May 01, 2010
Study Type : Meta Analysis
Additional Links
Diseases : Alzheimer's Disease, Bradycardia, Epileptic Seizures
Problem Substances : Donepezil (trade name Aricept), Memantine
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The WHO reports 71,471 seizures from a variety of neuroactive drugs between 1968-2006.Mar 01, 2010

Pubmed Data : Seizure. 2010 Mar;19(2):69-73. Epub 2009 Dec 24. PMID: 20036167
Article Published Date : Mar 01, 2010
Study Type : Meta Analysis
Additional Links
Diseases : Seizures
Problem Substances : Amoxapine, Buproprione , Chlorprothiexene , Clozapine, Donepezil (trade name Aricept), Escitaloprame, Maprotilene , Quetiapine, Rivastigmine, Trimipramine
Adverse Pharmacological Actions : Neurotoxic
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Acupuncture improves the overall function, cognition and activity of daily life in patients and the efficacy was superior to donepezil.Nov 30, 2014

Pubmed Data : Zhongguo Zhen Jiu. 2014 Dec ;34(12):1156-60. PMID: 25876339
Article Published Date : Nov 30, 2014
Study Type : Human Study
Additional Links
Diseases : Alzheimer's Disease
Therapeutic Actions : Acupuncture
Additional Keywords : Donepezil Alternatives, Mind-Body Medicine, Therapeutic Action Superior to Drug Therapy
Problem Substances : Donepezil (trade name Aricept)
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A case of dementia with Lewy bodies showing cervical dystonia after donepezil administration has been reported.Mar 01, 2010

Pubmed Data : Rinsho Shinkeigaku. 2010 Mar;50(3):147-50. PMID: 20235482
Article Published Date : Mar 01, 2010
Study Type : Human: Case Report
Additional Links
Diseases : Cervical Dystonia, Liver Failure: Drug Induced
Problem Substances : Donepezil (trade name Aricept)
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Donepezil-associated bradyarrhythmia in a patient with dementia with Lewy bodies (DLB) has been reported.Apr 01, 2010

Pubmed Data : Alzheimer Dis Assoc Disord. 2010 Apr-Jun;24(2):209-11. PMID: 20505440
Article Published Date : Apr 01, 2010
Study Type : Human: Case Report
Additional Links
Diseases : Bradycardia, Dementia, Dementia with Lewy bodies (DLB)
Problem Substances : Donepezil (trade name Aricept)
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Donepezil markedly potentiates memantine neurotoxicity.Feb 01, 2008

Pubmed Data : Neurobiol Aging. 2008 Feb ;29(2):153-67. Epub 2006 Nov 16. PMID: 17112636
Article Published Date : Feb 01, 2008
Study Type : Animal Study
Additional Links
Diseases : Alzheimer's Disease, Neurodegenerative Diseases
Pharmacological Actions : Apoptotic
Additional Keywords : Drug Synergy
Problem Substances : Donepezil (trade name Aricept), Memantine
Adverse Pharmacological Actions : Neurotoxic
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Rosmarinic acid represents a potential therapeutic option against chronic ethanol-induced amnesia.Jun 30, 2016

Pubmed Data : Nutr Neurosci. 2016 Jul 1:1-8. Epub 2016 Jul 1. PMID: 27367870
Article Published Date : Jun 30, 2016
Study Type : Animal Study
Additional Links
Substances : Rosmarinic acid
Diseases : Alcohol Toxicity , Amnesia: Drug-Induced
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Dose Response, Natural Substances Versus Drugs
Problem Substances : Donepezil (trade name Aricept)
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The cholinesterase inhibitor drugs may increase tremor and exacerbation of Parkinson's disease.Oct 01, 2007

Pubmed Data : Prescrire Int. 2007 Oct;16(91):197-8. PMID: 17926835
Article Published Date : Oct 01, 2007
Study Type : Review
Additional Links
Diseases : Alzheimer's Disease, Dementia, Parkinson's Disease, Parkinsonism, Tremor
Problem Substances : Cholinesterase Inhibitor Drugs, Donepezil (trade name Aricept), Galantamine, Rivastigmine
Adverse Pharmacological Actions : Neurotoxic

Donepezil (trade name Aricept) Related Articles

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Could the active ingredient in marijuana, responsible for its characteristic "high," help turn the tide against the accelerating Alzheimer's epidemic? A remarkable study published in the journal Molecular Pharmacology in 2006, found that this long vilified plant may contain a compound with not one, but two therapeutic properties ideal for addressing both the surface symptom (memory problems) and root cause (brain plaque) of Alzheimer’s disease
Declaring Chemical Warfare On The Brain: Alzheimer's Drugs Are Neurotoxicants
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What does the 4 billion a year, blockbuster Alzheimer's drug donepezil (trade name Aricept) have in common with insecticides, chemical weapons and venom? Quite a lot more than consumers taking them have been lead to believe.
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Alzheimer's disease is expanding unchecked throughout the modern world, despite billions spent annually on pharmaceutical interventions. Could the calcification of the brain play a role?

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