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5 Diseases Researched for Glucose

Name	AC	CK
Colon Cancer	1	2
DNA damage	1	2
Morphine Tolerance/Dependence	1	2
Aging	1	1
Cancers: All	1	1

1 Adverse Pharmacological Actions Researched for Glucose

Name	AC	CK	Focus
Progeriatric	1	1

Research Articles 5
Cumulative Knowledge Score 8
Overall Research Rating GOOD

View the Evidence:
10 Abstracts with Glucose Research

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High glucose levels spike reactive oxygen species production by mitochondria and neuron apoptosis.Nov 01, 2002

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Pubmed Data : FASEB J. 2002 Nov ;16(13):1738-48. PMID: 12409316

Article Published Date : Nov 01, 2002

Study Type : Human In Vitro

Additional Links

Diseases : Mitochondrial Dysfunction , Neurodegenerative Diseases, Oxidative Stress

Problem Substances : Glucose

[+]

Hyperglycemia induces mitochondrial dysfunction by a O-GlcNAc-independent mechanism.Apr 01, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biochem J. 2015 Apr 1 ;467(1):115-26. PMID: 25627821

Article Published Date : Apr 01, 2015

Study Type : Human In Vitro

Additional Links

Diseases : Mitochondrial Dysfunction , Oxidative Stress

Problem Substances : Glucose

[+]

Duodenal and portal glucose changes shown to regulate eating behaviour via brain area modulationsApr 03, 2012

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Pubmed Data : J Neuroendocrinol. 2012 Apr 4. Epub 2012 Apr 4. PMID: 22487360

Article Published Date : Apr 03, 2012

Study Type : Animal Study

Additional Links

Diseases : Blood-Brain-Barrier Disorders, Eating Disorders, Gut Brain Axis: Imbalance

Pharmacological Actions : Brain-derived neurotrophic factor modulator

Additional Keywords : Caudate, Orbitofrontal Cortex, Prepyriform, Putamen

Problem Substances : Glucose

[+]

Mutant Drosophilia flies genetically predisposed to mitochondrial dysfunction exhibit metabolic crisis with a high sugar diet.Jan 01, 2016

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Pubmed Data : PLoS One. 2016 ;11(1):e0145836. Epub 2016 Jan 26. PMID: 26812173

Article Published Date : Jan 01, 2016

Study Type : Animal Study

Additional Links

Diseases : Mitochondrial Dysfunction

Problem Substances : Glucose

[+]

Sucrose, glucose and fructose have similar genotoxicity in the rat colon. Feb 01, 2008

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Pubmed Data : Food Chem Toxicol. 2008 Feb;46(2):752-60. Epub 2007 Oct 1. PMID: 17988776

Article Published Date : Feb 01, 2008

Study Type : Animal Study

Additional Links

Diseases : Colon Cancer, DNA damage

Problem Substances : Fructose, Glucose, Sucrose

[+]

The antagonism of morphine-induced antinociception by glucose and fructose is due to a direct effect of these sugars or their metabolic products within the central nervous system.Feb 09, 1988

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Pubmed Data : Eur J Pharmacol. 1988 Feb 9 ;146(2-3):337-40. PMID: 3371404

Article Published Date : Feb 09, 1988

Study Type : Animal Study

Additional Links

Diseases : Morphine Tolerance/Dependence

Pharmacological Actions : Analgesics

Additional Keywords : Food Opioids, Fructose-Opiate Connection

Problem Substances : Fructose, Glucose

[+]

Glucose induces oxidative stress, especially by superoxide radical generation.Sep 01, 2002

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Pubmed Data : Curr Opin Clin Nutr Metab Care. 2002 Sep ;5(5):561-8. PMID: 12172481

Article Published Date : Sep 01, 2002

Study Type : Review

Additional Links

Diseases : Oxidative Stress

Pharmacological Actions : Antioxidants

Problem Substances : Glucose

[+]

Glucose signaling has a progeriatric effect on chronologically aged yeast cells.Oct 01, 2010

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Pubmed Data : Aging (Albany NY). 2010 Oct;2(10):643-9. PMID: 21076182

Article Published Date : Oct 01, 2010

Study Type : In Vitro Study

Additional Links

Diseases : Aging

Problem Substances : Glucose

Adverse Pharmacological Actions : Progeriatric

[+]

Increased glucose uptake activates known oncogenic pathways to induce malignant phenotypes. Jan 01, 2014

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Clin Invest. 2014 Jan 2 ;124(1):367-84. Epub 2013 Dec 9. PMID: 24316969

Article Published Date : Jan 01, 2014

Study Type : In Vitro Study

Additional Links

Diseases : Breast Cancer, Cancers: All

Additional Keywords : Cancer Glycolysis, Cell Transformation, Oncogenesis Promotion

Problem Substances : Glucose, Sugar

[+]

Sugars, primarily glucose and fructose, may contribute to cancer cell growth. Jan 01, 2010

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Pubmed Data : Int J Endocrinol. 2010;2010. Epub 2010 Jul 18. PMID: 20706540

Article Published Date : Jan 01, 2010

Study Type : Review

Additional Links

Diseases : Cancers: All

Problem Substances : Fructose, Glucose

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Focus Your Research

Click any topic below to filter + focus research

View the Evidence: 10 Abstracts with Glucose Research

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Currently Available Sorting Options

High glucose levels spike reactive oxygen species production by mitochondria and neuron apoptosis.Nov 01, 2002

Hyperglycemia induces mitochondrial dysfunction by a O-GlcNAc-independent mechanism.Apr 01, 2015

Duodenal and portal glucose changes shown to regulate eating behaviour via brain area modulationsApr 03, 2012

Mutant Drosophilia flies genetically predisposed to mitochondrial dysfunction exhibit metabolic crisis with a high sugar diet.Jan 01, 2016

Sucrose, glucose and fructose have similar genotoxicity in the rat colon. Feb 01, 2008

The antagonism of morphine-induced antinociception by glucose and fructose is due to a direct effect of these sugars or their metabolic products within the central nervous system.Feb 09, 1988

Glucose induces oxidative stress, especially by superoxide radical generation.Sep 01, 2002

Glucose signaling has a progeriatric effect on chronologically aged yeast cells.Oct 01, 2010

Increased glucose uptake activates known oncogenic pathways to induce malignant phenotypes. Jan 01, 2014

Sugars, primarily glucose and fructose, may contribute to cancer cell growth. Jan 01, 2010

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Glucose

View the Evidence:
10 Abstracts with Glucose Research