Glyphosate

Name	AC	CK
Glyphosate Toxicity	235	721
Oxidative Stress	23	86
Prenatal Chemical Exposures	29	72
Pesticide Toxicity	12	70
DNA damage	15	53
Infertility: Male	17	49
Lymphoma: Non-Hodgkin	2	40
Chemically-Induced Liver Damage	13	39
Non-Hodgkin Lymphoma	3	32
Inflammation	8	30
Lymphoma	2	30
Diabetes Mellitus: Type 2	4	25
Hormonal Disorders: Children	2	24
Herbicide Toxicity	4	23
Testosterone: Too Low	3	23
Kidney Damage: Chemically-Induced	8	22
Hairy Leukoplakia	1	20
Dysbiosis	11	18
Depression	5	17
Infertility: Female	8	15
Parkinson's Disease	5	15
Obesity	3	14
Skin Cancer	3	14
Alzheimer's Disease	2	12
Chemical Exposure	3	12
Hypertension	2	12
Multiple Myeloma	2	12
Cognitive Decline/Dysfunction	2	11
Nonalcoholic fatty liver disease (NAFLD)	4	11
Aging	1	10
All-Cause Mortality	1	10
Allergic Airway Diseases	1	10
Anemia	1	10
Blood Diseases	1	10
Bone Diseases	1	10
Cardiovascular Diseases	1	10
Hemolytic Anemia	1	10
Leukemia	1	10
Low Testosterone	1	10
Lung Damage	1	10
Melanoma	1	10
Metabolic Syndrome X	1	10
Muscular Diseases	1	10
Neurodegenerative Diseases	7	10
Osteoarthritis	1	10
Pregnancy Complications	1	10
Rheumatoid Arthritis	1	10
Rhinitis	1	10
Neurotoxicity	5	9
Liver Cancer	2	8
Parkinsonian Disorders	4	8
Brain Inflammation	3	6
Endocrine Diseases	2	6
Female Reproductive Development Abnormalities	4	6
Lipid Peroxidation	4	6
Testicular Injury: Chemical/Metal Induced	3	6
Insulin Resistance	2	5
Male Reproductive Development Abnormalities	3	5
Parkinsonism	2	5
Cancers: All	2	4
Chemical Poisoning: Accumulated Environmental Toxins	1	4
Chronic Kidney Disease of Unknown Etiology (CKDu)	2	4
Dopamine Levels: Low	2	4
Mercury Poisoning	1	4
Microcephaly	1	4
Postnatal Care: Breastfeeding	1	4
Pregnancy: Environmental Exposures	1	4
Sperm Quality: Low	2	4
Substantia Nigra: Damage	2	4
Breast Cancer	3	3
Lipopolysaccharide-Induced Toxicity	2	3
Meningitis: Aseptic	1	3
Vaccine-induced Toxicity	1	3
Aflatoxicosis	1	2
Air Pollution Linked Toxicity	1	2
Anxiety	1	2
Arsenic Poisoning	1	2
Asthma	1	2
Autism	2	2
Autism Spectrum Disorders	2	2
Bee Colony Collapse	1	2
Botulism	1	2
Botulism: Infantile	1	2
Brain: Oxidative Stress	1	2
Breast Diseases	1	2
Endothelial Dysfunction	1	2
Fatty Liver	1	2
Gastrointestinal Inflammation	1	2
Heavy Metal Toxicity	1	2
Hepatic Steatosis	1	2
High Fat Diet	1	2
Kidney Diseases	1	2
Learning disorders	1	2
Lung Diseases	1	2
Lung Inflammation	1	2
Neurodevelopmental Disorders	1	2
Osteoporosis	1	2
Thyroid Diseases	2	2
Acetaminophen (Tylenol) Toxicity	1	1
Aluminum Toxicity	1	1
Antibiotic Toxicity	1	1
Breast Cancer: Chemically-Induced	1	1
Breast Cancer: estrogen receptor alpha-positive	1	1
Cancer Metastasis	1	1
Cancers: Drug Resistant	1	1
Cholangiocarcinoma	1	1
Chronic Kidney Disease (CKD)	1	1
Clostridium Infections	1	1
Escherichia coli Infections	1	1
Genital Diseases: Male	1	1
Glioblastoma	1	1
Kidney Damage	1	1
Liver Damage	1	1
Lymphatic Cancer	1	1
Mitochondrial Dysfunction	1	1
Neurological Damage	1	1
Pesticide Toxicity: Cypermethrin	1	1
Uranium Poisoning	1	1

Name	AC	CK
Neurotoxic	40	101
Genotoxic	18	50
Endocrine Disruptor	11	45
Carcinogen	3	42
Oxidant	7	38
Cytotoxic	10	21
Anti-Fertility	1	20
Aquacidal	8	20
Gastrotoxic	8	13
Hepatotoxic	6	13
Biocide	3	10
Diabetogenic	1	10
Teratogenic	3	10
Aromatase Disruptor	2	7
Bioaccumulator	3	7
Acetylcholinesterase inhibitor (xenobiotic)	3	6
Inflammatory	3	6
Clastogenic	1	5
Mutagenic	3	5
Apoptotic	3	4
Cardiotoxic	2	4
Endocrine Disruptor: Testes	2	4
Immunosuppressive	2	4
Immunotoxic	3	4
Carcinogenic	2	3
Cell Cycle Inhibitor	3	3
Glutathione Down-Regulation	2	3
Glutathione S-transferase Inducer (xenobiotic)	2	3
Nephrotoxic	2	3
Excitotoxic	1	2
Malondialdehyde (MDA) Up-Regulation	1	2
Necrotic	1	2
Obesogenic	1	2
Renotoxic	1	2
Estrogenic	1	1
Immunoreactive	1	1
Proliferative	1	1

[+]

Widespread occurrence of glyphosate in urine from pet dogs and cats in New York State, USA.Mar 31, 2019

Click here to read the entire abstract

Pubmed Data : Sci Total Environ. 2019 Apr 1 ;659:790-795. Epub 2018 Dec 31. PMID: 31096409

Article Published Date : Mar 31, 2019

Study Type : Animal Study

Additional Links

Diseases : Glyphosate Toxicity

Problem Substances : Glyphosate

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Zinc supplementation mitigated glyphosate-based herbicide immunotoxicity.Dec 31, 2022

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Int Med Res. 2023 Jan ;51(1):3000605221147188. PMID: 36636770

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Pubmed Data : J Toxicol Environ Health B Crit Rev. 2012 ;15(1):39-96. PMID: 22202229

Article Published Date : Jan 01, 2012

Study Type : Review

Additional Links

Additional Keywords : Junk Science

Problem Substances : Glyphosate

[+]

"Effect of pesticides on cell survival in liver and brain rat tissues."Oct 01, 2009

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Pubmed Data : Ecotoxicol Environ Saf. 2009 Oct ;72(7):2025-32. Epub 2009 Jun 2. PMID: 19493570

[+]

Exposure to glyphosate- and/or Mn/Zn-ethylene-bis-dithiocarbamate-containing pesticides leads to degeneration ofγ-aminobutyric acid and dopamine neurons in Caenorhabditis elegans.Apr 01, 2012

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Pubmed Data : Neurotox Res. 2012 Apr ;21(3):281-90. Epub 2011 Sep 16. PMID: 21922334

Article Published Date : Apr 01, 2012

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Pubmed Data : Chemosphere. 2009 Oct ;77(4):582-9. Epub 2009 Jul 21. PMID: 19625069

Article Published Date : Oct 01, 2009

Study Type : Plant Study

Additional Links

Problem Substances : Aminomethylphosphonic acid (AMPA), Glyphosate

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Glyphosate and AMPA could disturb chlorophyll contents and reduce photosynthesis rates of willow species. May 31, 2016

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Pubmed Data : Pestic Biochem Physiol. 2016 Jun ;130:65-70. Epub 2015 Nov 28. PMID: 27155486

Article Published Date : May 31, 2016

Study Type : Plant Study

Additional Links

Diseases : Glyphosate Toxicity

Problem Substances : Aminomethylphosphonic acid (AMPA), Glyphosate

[+]

Glyphosate as a direct or indirect activator of pro-inflammatory signaling and cognitive impairment.Sep 30, 2024

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Pubmed Data : Neural Regen Res. 2024 Oct 1 ;19(10):2212-2218. Epub 2023 Dec 21. PMID: 38488555

Article Published Date : Sep 30, 2024

Study Type : Review

Additional Links

Diseases : Cognitive Decline/Dysfunction, Glyphosate Toxicity

Pharmacological Actions : Neuroprotective Agents

Problem Substances : Glyphosate

Adverse Pharmacological Actions : Neurotoxic

[+]

Glyphosate dramatically affects nutritional seed composition in glyphosate-resistant soybean.Apr 14, 2010

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Pubmed Data : J Agric Food Chem. 2010 Apr 14 ;58(7):4517-22. PMID: 20307082

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Bioengineered. 2021 Dec ;12(1):63-69. PMID: 33345705

Click here to read the entire abstract

Pubmed Data : Chem Res Toxicol. 2009 Jan;22(1):97-105. PMID: 19105591

Article Published Date : Jan 01, 2009

Study Type : In Vitro Study

Additional Links

Diseases : Prenatal Chemical Exposures

Problem Substances : Glyphosate, Glyphosate formulations, Roundup (herbicide)

Adverse Pharmacological Actions : Necrotic

[+]

Glyphosate has been linked to lymphatic cancer. Jan 01, 2003

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Pubmed Data : Med Pr. 2003 ;54(6):579-83. PMID: 15055003

Article Published Date : Jan 01, 2003

Study Type : Review

Additional Links

Diseases : Lymphatic Cancer

Problem Substances : Glyphosate

[+]

Glyphosate has genotoxic properties. Jan 01, 2006

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Glyphosate's synergistic toxicity in combination with other factors as a cause of chronic kidney disease of unknown origin.Jul 30, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Environ Res Public Health. 2019 Jul 31 ;16(15). Epub 2019 Jul 31. PMID: 31370256

Article Published Date : Jul 30, 2019

Study Type : Review

Additional Links

Diseases : Chronic Kidney Disease (CKD), Glyphosate Toxicity, Kidney Damage: Chemically-Induced

Additional Keywords : Synergistic Toxicity

Problem Substances : Glyphosate, Paraquat

[+]

Glyphosate, despite its low mobility in soils, is capable of reaching groundwater. 41% of 140 groundwater samples from Catalonia Spain contained high levels, technically beyond the limit of quantification. Nov 20, 2011

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Pubmed Data : Anal Bioanal Chem. 2011 Nov 20. Epub 2011 Nov 20. PMID: 22101424

Article Published Date : Nov 20, 2011

Study Type : Review

Additional Links

Additional Keywords : Groundwater Contamination

Problem Substances : Glyphosate

[+]

Glyphosate, hard water and nephrotoxic metals: are they the culprits behind the epidemic of chronic kidney disease of unknown etiology in sri lanka?Dec 31, 2013

[+]

Glyphosphate exhibits genotoxicity in human cells. Sep 01, 2005

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Pubmed Data : Biomedica. 2005 Sep;25(3):335-45. PMID: 16276681

Article Published Date : Sep 01, 2005

Study Type : In Vitro Study

Additional Links

Diseases : DNA damage

Problem Substances : Glyphosate

Adverse Pharmacological Actions : Genotoxic

[+]

Glyphosphate exhibits toxicity as very low concentrations. Jan 01, 2011

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Pubmed Data : Ecotoxicology. 2011 Jan;20(1):255-63. Epub 2010 Nov 18. PMID: 21086158

Pubmed Data : Plant Biol (Stuttg). 2023 Jun ;25(4):571-578. Epub 2023 Mar 30. PMID: 36920172

Roundup Disrupted Male Reproductive Functions By Triggering Calcium-Mediated Cell Death In Rat Testis And Sertoli Cells.Jun 28, 2013

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Pubmed Data : Free Radic Biol Med. 2013 Jun 29. Epub 2013 Jun 29. PMID: 23820267

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Pubmed Data : Arch Toxicol. 2012 Feb 14. Epub 2012 Feb 14. PMID: 22331240

Article Published Date : Feb 14, 2012

Study Type : In Vitro Study

Additional Links

Diseases : Cancers: All, DNA damage

Problem Substances : Glyphosate, Roundup (herbicide)

Adverse Pharmacological Actions : Genotoxic

[+]

Roundup is a common herbicide that has been used in suicide due to its high level of toxicity. Jul 22, 2010

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Pubmed Data : J Clin Neurosci. 2010 Jul 22. Epub 2010 Jul 22. PMID: 20655231

Article Published Date : Jul 22, 2010

Study Type : Commentary

Additional Links

Problem Substances : Glyphosate, Isopropylamine (IPA), Polyoxyethylene amine, Roundup (herbicide)

[+]

Sub-lethal glyphosate exposure alters flowering phenology and causes transient male-sterility in Brassica spp.Dec 31, 2013

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Article Publish Status : This is a free article. Click here to read the complete article.

This review reveals a coherent body of evidence indicating that GlyBH could be toxic below the regulatory lowest observed adverse effect level for chronic toxic effects.Aug 13, 2015

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Pubmed Data : Food Chem Toxicol. 2015 Aug 14. Epub 2015 Aug 14. PMID: 26282372

Article Published Date : Aug 13, 2015

Study Type : Review

Additional Links

Diseases : Herbicide Toxicity

Problem Substances : Glyphosate

Adverse Pharmacological Actions : Endocrine Disruptor

[+]

Toxicity induced by glyphosate and glyphosate-based herbicides in the zebrafish hepatocyte cell line.Oct 29, 2018

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Pubmed Data : Ecotoxicol Environ Saf. 2018 Oct 30 ;162:201-207. Epub 2018 Jul 11. PMID: 29990732

Article Published Date : Oct 29, 2018

Study Type : In Vitro Study

Additional Links

Diseases : Glyphosate Toxicity

Problem Substances : Glyphosate

[+]

Toxicity of pesticides toward human immune cells U-937 and HL-60.Dec 31, 2019

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Pubmed Data : J Environ Sci Health B. 2020 ;55(8):719-725. Epub 2020 Jun 13. PMID: 32538258

Article Published Date : Dec 31, 2019

Study Type : In Vitro Study

Additional Links

Diseases : Glyphosate Toxicity, Pesticide Toxicity

Problem Substances : Deltamethrin, Glyphosate, Pesticides

Adverse Pharmacological Actions : Immunoreactive

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View the Evidence: 396 Abstracts with Glyphosate Research

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Widespread occurrence of glyphosate in urine from pet dogs and cats in New York State, USA.Mar 31, 2019

Zinc supplementation mitigated glyphosate-based herbicide immunotoxicity.Dec 31, 2022

Glyphosate-based herbicide formulations and reproductive toxicity in animals.Nov 30, 2020

Roundup exposure may adversely affect human reproduction and fetal development in case of contamination. Jul 01, 2007

The glyphosate formulation Roundup® LB plus influences the global metabolome of pig gut microbiota in vitro.Jul 16, 2020

"2,4-Dichlorophenoxyacetic acid (2,4-D)–resistant crops and the potential for evolution of 2,4-D–resistant weeds."Mar 15, 2011

"A glyphosate-based herbicide induces necrosis and apoptosis in mature rat testicular cells in vitro, and testosterone decrease at lower levels."Dec 19, 2011

"Developmental and reproductive outcomes in humans and animals after glyphosate exposure: a critical analysis."Jan 01, 2012

"Effect of pesticides on cell survival in liver and brain rat tissues."Oct 01, 2009

"Formulated glyphosate activates the DNA-response checkpoint of the cell cycle leading to the prevention of G2/M transition."Dec 01, 2004

"Glyphosate and pendimethalin could potentially be present in high concentrations (>0.1 μg L(-1)) in both water originating from the drainage system and the shallow groundwater located at the depth of the drainage system."Jul 01, 2011

"Pool of resistance mechanisms to glyphosate in Digitaria insularis."Jan 17, 2012

A commercial formulation of glyphosate inhibits proliferation and differentiation to adipocytes and induces programmed cell death in 3T3-L1 fibroblasts.Apr 21, 2012

A glyphosate-based pesticide impinges on transcription.Feb 15, 2005

A glyphosate-mediated male plant sterility system using miRNA has been produced. Dec 31, 2017

A review of the impact of glyphosate-induced intestinal dysbiosis on the central nervous system.Aug 19, 2019

Activation of the N-methyl-d-aspartate receptor is involved in glyphosate-induced renal proximal tubule cell apoptosis.Jul 31, 2019

Agricultural practices that involve the use of herbicides such as Roundup affect non-target organisms and the water quality, modifying the structure and functionality of freshwater ecosystems.Apr 01, 2010

Aluminum-induced entropy in biological systems: implications for neurological disease.Dec 31, 2013

Ameliorative potential of vitamin C and E against Roundup-glyphosate induced genotoxicity.Jun 29, 2022

Bt toxins are not inert on nontarget human cells, and that they can present combined side-effects with other residues of pesticides specific to GM plants.Feb 15, 2012

Clarification of the molecular mechanisms underlying glyphosate-induced major depressive disorder.Jan 30, 2024

Clear toxicities of pollutants were observed cell lines at very low sub-agricultural dilutions.Jan 01, 2011

Comparative effects of the Roundup and glyphosate on mitochondrial oxidative phosphorylation.Nov 30, 2005

Could glyphosate and glyphosate-based herbicides be associated with increased thyroid diseases worldwide? Dec 31, 2020

Effective attenuation of glyphosate-induced oxidative stress and granulosa cell apoptosis by vitamins C and E in caprines.Nov 07, 2018

Effects of glyphosate and aminomethylphosphonic acid on an isogeneic model of the human blood-brain barrier.Dec 30, 2018

Effects of Glyphosate and Roundup on the mammalian nervous system: A review.Jul 18, 2022

Environmental glyphosate levels may deleteriously influence the gut-brain axis by boosting the growth of Clostridium bacteria in autistic toddlers.Apr 03, 2018

Epigenetic changes associated with exposure to glyphosate-based herbicides in mammals.Dec 31, 2020

Evidence the U.S. autism epidemic initiated by acetaminophen is aggravated by oral antibiotics and now exponentially by herbicide glyphosate.Jan 31, 2018

Exposure to glyphosate produces important alterations in the structure and function of the nervous system of humans, rodents, fish, and invertebrates.Apr 20, 2022

Exposure to glyphosate- and/or Mn/Zn-ethylene-bis-dithiocarbamate-containing pesticides leads to degeneration ofγ-aminobutyric acid and dopamine neurons in Caenorhabditis elegans.Apr 01, 2012

For the first time in a higher plant, two concurrent pathways capable of degrading glyphosate to AMPA, Pi, glyoxylate, sarcosine and formaldehyde as end products were identified.Dec 31, 2011

Formulants of glyphosate-based herbicides have more deleterious impact than glyphosate on TM4 Sertoli cells.Sep 30, 2018

Glyphosate (and its metabolite) herbicide degradation in soil may be delayed through interception by plants.Oct 01, 2009

Glyphosate and AMPA could disturb chlorophyll contents and reduce photosynthesis rates of willow species. May 31, 2016

Glyphosate as a direct or indirect activator of pro-inflammatory signaling and cognitive impairment.Sep 30, 2024

Glyphosate dramatically affects nutritional seed composition in glyphosate-resistant soybean.Apr 14, 2010

Glyphosate drives autophagy-dependent ferroptosis to inhibit testosterone synthesis in mouse Leydig cells.Feb 29, 2024

Glyphosate effect on biofilms formation, mutagenesis and stress response of E. сoli.Jan 04, 2024

Glyphosate escalates horizontal transfer of conjugative plasmid harboring antibiotic resistance genes.Nov 30, 2021

Glyphosate exposure could interfere with mouse oocyte maturation by generating oxidative stress and early apoptosis.Jul 22, 2019

Glyphosate exposure likely disrupts the balance of friendly and pathogenic bacteria in our guts.Dec 08, 2012

Glyphosate favored a more metastatic and chemoresistant behavior in cancer cells.Mar 25, 2024

Glyphosate formulations induce apoptosis and necrosis in human umbilical, embryonic, and placental cells.Jan 01, 2009

Glyphosate has been linked to lymphatic cancer. Jan 01, 2003

Glyphosate has genotoxic properties. Jan 01, 2006

Glyphosate herbicide: reproductive outcomes and multigenerational effects. Dec 31, 2020

Glyphosate herbicides may exhibit sublethal adverse effects on non-pest insects.Feb 01, 2010

Glyphosate induces cell death through apoptotic and autophagic mechanisms, indicating a mechanism behind the association between glyphosate exposure and Parkinsonism. Apr 04, 2012

Glyphosate induces growth of estrogen receptor alpha positive cholangiocarcinoma cells.Jun 07, 2018

Glyphosate induces human breast cancer cells growth via estrogen receptors.Jun 07, 2013

Glyphosate mimics 17β-estradiol effects promoting estrogen receptor alpha activity in breast cancer cells.Jan 31, 2023

Glyphosate negatively affects associative learning processes of foragers, cognitive and sensory abilities of young hive bees.Oct 17, 2019

Glyphosate pesticide (Roundup) exposure may adversely alter estrogen-related gene expression.Sep 01, 2007

Glyphosate pesticides are cytotoxic to human peripheral blood mononuclear cells.Dec 01, 2007

Glyphosate primes mammary cells for tumorigenesis by reprogramming the epigenome in a TET3-dependent manner.Dec 31, 2018

Glyphosate residues in soil affect crop plant germination and growth.Jan 22, 2019

Glyphosate suppresses the antagonistic effect of Enterococcus spp. on Clostridium botulinum.Feb 05, 2013

Glyphosate treatment led to a reduction in pollen viability of rose plants.Dec 31, 2020

Glyphosate's synergistic toxicity in combination with other factors as a cause of chronic kidney disease of unknown origin.Jul 30, 2019

Glyphosate, despite its low mobility in soils, is capable of reaching groundwater. 41% of 140 groundwater samples from Catalonia Spain contained high levels, technically beyond the limit of quantification. Nov 20, 2011

Glyphosate, hard water and nephrotoxic metals: are they the culprits behind the epidemic of chronic kidney disease of unknown etiology in sri lanka?Dec 31, 2013

Glyphosate-based herbicides are toxic and endocrine disruptors in human cell lines at exceedingly small concentrations (.5 ppm to 10 ppm).Aug 21, 2009

Glyphosate-based herbicides could potently affect the cardiovascular system in mammals.Mar 31, 2015

Glyphosate-based herbicides induces autophagy in IPEC-J2 cells and the intervention of N-acetylcysteine.Jul 31, 2022

Glyphosate-based herbicides was able to inhibit proliferation and differentiation of preadipocytes and to induce oxidative stress.Apr 03, 2016

Glyphosate-based pesticides adversely affect cell cycle regulation at concentrations 500 to 4000 times lower than used in agriculatural applications. Apr 01, 2004

Glyphosate-induced glioblastoma cell proliferation: Unraveling the interplay of oxidative, inflammatory, proliferative, and survival signaling pathways.Nov 30, 2023

Glyphosate: Impact on the microbiota-gut-brain axis and the immune-nervous system, and clinical cases of multiorgan toxicity.Jan 31, 2024

Glyphosate

View the Evidence:
396 Abstracts with Glyphosate Research