Herbicide

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39 Diseases Researched for Herbicide
NameACCKFocus
Lymphoma: Non-Hodgkin220Locked
Hormonal Disorders: Children212Locked
Cancers: All211Locked
Testosterone: Too Low211Locked
Diabetes Mellitus: Type 2110Locked
Hairy Leukoplakia110Locked
Lymphoma110Locked
Myelodysplastic Syndrome110Locked
Myocardial Infarction110Locked
Pesticide Toxicity 110Locked
Rhinitis110Locked
Prenatal Chemical Exposures69Locked
DNA damage46Locked
Oxidative Stress26Locked
Blood Diseases15Locked
Glyphosate Toxicity35Locked
Hemolytic Anemia15Locked
Herbicide Toxicity25Locked
Endocrine Diseases23Locked
Infertility: Male23Locked
Alzheimer's Disease12Locked
Brain Inflammation 12Locked
Chemical Poisoning: Accumulated Environmental Toxins12Locked
Mercury Poisoning12Locked
Microcephaly12Locked
Neurotoxicity12Locked
Nonalcoholic fatty liver disease (NAFLD)12Locked
Parkinson's Disease12Locked
Parkinsonism12Locked
Postnatal Care: Breastfeeding12Locked
Pregnancy: Environmental Exposures12Locked
Skin Cancer22Locked
Botulism11Locked
Botulism: Infantile11Locked
Chronic Kidney Disease of Unknown Etiology (CKDu)11Locked
Genital Diseases: Male11Locked
Kidney Damage: Chemically-Induced11Locked
Kidney Diseases11Locked
Mitochondrial Dysfunction 11Locked
21 Adverse Pharmacological Actions Researched for Herbicide
NameACCKFocus
Carcinogen321Locked
Endocrine Disruptor821Locked
Genotoxic610Locked
Aquacidal36Locked
Biocide35Locked
Cytotoxic45Locked
Hepatotoxic24Locked
Neurotoxic24Locked
Teratogenic24Locked
Oxidant23Locked
Bioaccumulator12Locked
Excitotoxic12Locked
Mutagenic22Locked
Aromatase Disruptor11Locked
Carcinogenic11Locked
Endocrine Disruptor: Testes11Locked
Glutathione Down-Regulation11Locked
Glutathione S-transferase Inducer (xenobiotic)11Locked
Immunosuppressive11Locked
Necrotic11Locked
Nephrotoxic11Locked
Related Topics

The Following are Sub-Topics of Herbicide

View the Evidence:
60 Abstracts with Herbicide Research

[+]

2,4-D exposure is associated with perturbations of lipid and glucose metabolism which may be associated with higher risk for acute myocardial infarction and type-2 diabets.Jan 01, 2010

Pubmed Data : Environ Health. 2010;9:11. Epub 2010 Feb 26. PMID: 20187939
Article Published Date : Jan 01, 2010
Study Type : Human Study
Additional Links
Diseases : Diabetes Mellitus: Type 2, Myocardial Infarction
Problem Substances : Chlorophenoxy herbicide
[+]

Conventional wheat production requires the use of carcinogenic herbicides and proximity to wheat agiculture is associated with higher prevalance of a variety of cancers.Sep 01, 2000

Pubmed Data : Environ Health Perspect. 2000 Sep;108(9):873-81. PMID: 11017893
Article Published Date : Sep 01, 2000
Study Type : Human Study
Additional Links
Diseases : Cancers: All
Problem Substances : Chlorophenoxy herbicide
[+]

Exposure to various chemicals is associated with increased risk for myelodysplastic syndrome according to the WHO.Feb 01, 2011

Pubmed Data : Am J Hematol. 2011 Feb;86(2):163-169. PMID: 21264898
Article Published Date : Feb 01, 2011
Study Type : Human Study
Additional Links
Diseases : Myelodysplastic Syndrome
Problem Substances : Benzene, Crude Oil/Petroleum, Herbicide, Pesticides, Tobacco: Smoking
[+]

Glyphosate can be detected in the urine of farmers and their families in farms where Roundup pesticide is used. Mar 01, 2004

Pubmed Data : Environ Health Perspect. 2004 Mar;112(3):321-6. PMID: 14998747
Article Published Date : Mar 01, 2004
Study Type : Human Study
Additional Links
Problem Substances : Glyphosate, Roundup (herbicide)
[+]

Glyphosate pesticide (Roundup) exposure is a risk factor for non-Hodgkin lymphoma and Hairy Cell leukemia.May 01, 2002

Pubmed Data : Leuk Lymphoma. 2002 May;43(5):1043-9. PMID: 12148884
Article Published Date : May 01, 2002
Study Type : Human Study
Additional Links
Diseases : Hairy Leukoplakia, Lymphoma, Lymphoma: Non-Hodgkin
Problem Substances : Glyphosate, Roundup (herbicide)
Adverse Pharmacological Actions : Carcinogen
[+]

Glyphosate pesticide (Roundup) exposure is a risk factor for non-Hodgkin lymphoma.Oct 01, 2008

Pubmed Data : Int J Cancer. 2008 Oct 1;123(7):1657-63. PMID: 18623080
Article Published Date : Oct 01, 2008
Study Type : Human Study
Additional Links
Diseases : Lymphoma: Non-Hodgkin
Problem Substances : Glyphosate, Roundup (herbicide)
Adverse Pharmacological Actions : Carcinogen
[+]

Glyphosphate exposure has been linked to rhinitis among pesticide applicators. Jan 01, 2010

Pubmed Data : J Toxicol Environ Health A. 2010;73(20):1382-93. PMID: 20818537
Article Published Date : Jan 01, 2010
Study Type : Human Study
Additional Links
Diseases : Rhinitis
Problem Substances : Pesticides, Roundup (herbicide)
[+]

Prepubertal exposure to commercial formulation of the herbicide glyphosate alters testosterone levels and testicular morphology.Apr 01, 2010

Pubmed Data : Arch Toxicol. 2010 Apr;84(4):309-17. Epub 2009 Dec 12. PMID: 20012598
Article Published Date : Apr 01, 2010
Study Type : Human Study
Additional Links
Diseases : Hormonal Disorders: Children, Pesticide Toxicity , Testosterone: Too Low
Additional Keywords : Environmental Pollutant
Problem Substances : Glyphosate, Roundup (herbicide)
Adverse Pharmacological Actions : Endocrine Disruptor
[+]

The effect of metabolites and impurities of glyphosate on human erythrocytes (in vitro).Jan 31, 2014

Pubmed Data : Pestic Biochem Physiol. 2014 Feb ;109:34-43. Epub 2014 Jan 25. PMID: 24581382
Article Published Date : Jan 31, 2014
Study Type : Human In Vitro
Additional Links
Diseases : Blood Diseases, Hemolytic Anemia, Oxidative Stress
Problem Substances : Aminomethylphosphonic acid (AMPA), Glyphosate, Roundup (herbicide)
[+]

Both the general health condition and reproductive success of J. multidenatata (fish) could be seriously affected by Roundup.Dec 31, 2011

Pubmed Data : Arch Environ Contam Toxicol. 2012 Jan ;62(1):107-17. Epub 2011 Jun 4. PMID: 21643816
Article Published Date : Dec 31, 2011
Study Type : Animal Study
Additional Links
Problem Substances : Glyphosate formulations, Roundup (herbicide)
Adverse Pharmacological Actions : Aquacidal, Endocrine Disruptor, Genotoxic
[+]

Commercial glyphosate herbicides exhibit genotoxicity in fish.Jul 01, 2007

Pubmed Data : Mutagenesis. 2007 Jul;22(4):263-8. Epub 2007 Apr 10. PMID: 17426049
Article Published Date : Jul 01, 2007
Study Type : Animal Study
Additional Links
Diseases : DNA damage
Problem Substances : Glyphosate, Roundup (herbicide)
Adverse Pharmacological Actions : Genotoxic
[+]

Compositional differences in soybeans on the market: Glyphosate accumulates in Roundup Ready GM soybeans.Jun 14, 2014

Pubmed Data : Food Chem. 2014 Jun 15 ;153:207-15. Epub 2013 Dec 18. PMID: 24491722
Article Published Date : Jun 14, 2014
Study Type : Environmental, Plant Study
Additional Links
Additional Keywords : GMOs, Organic Versus Conventional, Substantial Equivalence
Problem Substances : Glyphosate, Glyphosate formulations, Roundup (herbicide)
[+]

Genotoxic effects of the herbicide Roundup(®) have been observed in the fish species Corydoras paleatus after short-term, environmentally low concentration exposure.Jul 21, 2012

Pubmed Data : Environ Monit Assess. 2012 Jul 22. Epub 2012 Jul 22. PMID: 22821326
Article Published Date : Jul 21, 2012
Study Type : Animal Study, Environmental
Additional Links
Diseases : Glyphosate Toxicity
Problem Substances : Glyphosate, Glyphosate formulations, Roundup (herbicide)
Adverse Pharmacological Actions : Aquacidal, Genotoxic
[+]

Glyphosate and especially Roundup Ultra bioaccumulates and causes oxidative stress in freshwater worms.Jan 01, 2009

Pubmed Data : Environ Pollut. 2009 Jan;157(1):57-63. Epub 2008 Sep 14. PMID: 18790555
Article Published Date : Jan 01, 2009
Study Type : Animal Study
Additional Links
Problem Substances : Glyphosate, Roundup (herbicide)
Adverse Pharmacological Actions : Biocide
[+]

Glyphosate and Roundup toxicity to aquatic invertebrates have been underestimated and that current European Commission and US EPA toxicity classification of these chemicals need to be revised.Dec 05, 2012

Pubmed Data : Ecotoxicology. 2012 Dec 6. Epub 2012 Dec 6. PMID: 23224423
Article Published Date : Dec 05, 2012
Study Type : Animal Study
Additional Links
Diseases : Chemical Poisoning: Accumulated Environmental Toxins
Problem Substances : Glyphosate, Roundup (herbicide)
[+]

Glyphosate herbicides (Roundup) exhibit pre- and postnatal toxicity in rats.Sep 01, 2007

Pubmed Data : Arch Toxicol. 2007 Sep;81(9):665-73. Epub 2007 Jul 19. PMID: 17634926
Article Published Date : Sep 01, 2007
Study Type : Animal Study
Additional Links
Diseases : Postnatal Care: Breastfeeding, Pregnancy: Environmental Exposures, Prenatal Chemical Exposures
Problem Substances : Glyphosate, Polyoxyethylene amine, Roundup (herbicide)
Adverse Pharmacological Actions : Endocrine Disruptor
[+]

Glyphosate herbicides exhibit a wide range of toxicities to tadpoles.Jul 29, 2010

Pubmed Data : Arch Environ Contam Toxicol. 2010 Jul 29. Epub 2010 Jul 29. PMID: 20669015
Article Published Date : Jul 29, 2010
Study Type : Animal Study
Additional Links
Problem Substances : Glyphosate, Roundup (herbicide)
[+]

Glyphosate mediated control of giant reed results in adverse side-effects on the structure and function of a nearby river ecosystem.Aug 01, 2010

Pubmed Data : Environ Res. 2010 Aug;110(6):556-64. Epub 2010 Jun 11. PMID: 20541186
Article Published Date : Aug 01, 2010
Study Type : Animal Study
Additional Links
Additional Keywords : Environmental Pollutant
Problem Substances : Glyphosate, Roundup (herbicide)
[+]

Glyphosate-based herbicides produce teratogenic (birth defect causing) effects including microcephaly in vertebrates by impairing retinoic acid signaling. Oct 17, 2010

Pubmed Data : Chem Res Toxicol. 2010 Oct 18 ;23(10):1586-95. Epub 2010 Aug 9. PMID: 20695457
Article Published Date : Oct 17, 2010
Study Type : Animal Study
Additional Links
Diseases : Microcephaly
Problem Substances : Glyphosate, Roundup (herbicide)
Adverse Pharmacological Actions : Teratogenic
[+]

Groundup herbicide exhibits toxicity in North American frog species and results in malformations in tadpoles due perhaps to its endocrine disrupting activity.Aug 01, 2004

Pubmed Data : Environ Toxicol Chem. 2004 Aug;23(8):1928-38. PMID: 15352482
Article Published Date : Aug 01, 2004
Study Type : Animal Study
Additional Links
Problem Substances : Glyphosate, Polyoxyethylene amine, Roundup (herbicide)
[+]

Herbicide formulation with glyphosate adversely affects growth, acetylcholinesterase activity, and metabolic and hematological parameters in fish.Apr 01, 2010

Pubmed Data : Arch Environ Contam Toxicol. 2010 Apr;58(3):740-5. Epub 2010 Jan 30. PMID: 20112104
Article Published Date : Apr 01, 2010
Study Type : Animal Study
Additional Links
Additional Keywords : Environmental Pollutant
Problem Substances : Glyphosate, Roundup (herbicide)
Adverse Pharmacological Actions : Biocide
[+]

MECHANISMS UNDERLYING THE NEUROTOXICITY INDUCED BY GLYPHOSATE-BASED HERBICIDE IN IMMATURE RAT HIPPOCAMPUS: INVOLVEMENT OF GLUTAMATE EXCITOTOXICITY.Mar 13, 2014

Pubmed Data : Toxicology. 2014 Mar 14. Epub 2014 Mar 14. PMID: 24636977
Article Published Date : Mar 13, 2014
Study Type : Animal Study
Additional Links
Diseases : Alzheimer's Disease, Brain Inflammation , Neurotoxicity, Parkinson's Disease, Parkinsonism
Problem Substances : Glyphosate formulations, Roundup (herbicide)
Adverse Pharmacological Actions : Excitotoxic, Neurotoxic
[+]

Perinatal exposure to glyphosate-based herbicide alters the thyrotrophic axis and causes thyroid hormone homeostasis imbalance in male rats.Nov 30, 2016

Pubmed Data : Toxicology. 2016 Dec 1 ;377:25-37. Epub 2016 Dec 1. PMID: 27916585
Article Published Date : Nov 30, 2016
Study Type : Animal Study
Additional Links
Diseases : Glyphosate Toxicity, Prenatal Chemical Exposures
Problem Substances : Glyphosate, Roundup (herbicide)
[+]

Roundup causes oxidative stress in liver and inhibits acetylcholinesterase in muscle and brain of a neotropical fish.Jan 01, 2010

Pubmed Data : Chemosphere. 2010 Jan;78(3):294-9. Epub 2009 Nov 11. PMID: 19910015
Article Published Date : Jan 01, 2010
Study Type : Animal Study
Additional Links
Additional Keywords : Environmental Pollutant
Problem Substances : Glyphosate, Roundup (herbicide)
Adverse Pharmacological Actions : Aquacidal, Hepatotoxic, Neurotoxic, Oxidant
[+]

Roundup herbicide exhibits significant acute and chronic toxicity to freshwater mussels.Oct 01, 2007

Pubmed Data : Environ Toxicol Chem. 2007 Oct;26(10):2094-100. PMID: 17867870
Article Published Date : Oct 01, 2007
Study Type : Animal Study
Additional Links
Problem Substances : Glyphosate, Polyoxyethylene amine, Roundup (herbicide)
[+]

Roundup herbicide exhibits significant toxicity in larval amphibians, killing 50% of test species after 96 hours at concentrations that range between .8 mg and 3.2 mg per Liter. Sep 01, 2009

Pubmed Data : Environ Toxicol Chem. 2009 Sep;28(9):2004-8. PMID: 19405783
Article Published Date : Sep 01, 2009
Study Type : Animal Study
Additional Links
Additional Keywords : Environmental Pollutant
Problem Substances : Glyphosate, Polyoxyethylene amine, Roundup (herbicide)
[+]

Roundup herbicide may contribute to widespread amphibian declines due to its significant toxicity on tadpoles.Aug 01, 2010

Pubmed Data : Environ Pollut. 2010 Aug;158(8):2610-7. Epub 2010 Jun 11. PMID: 20541298
Article Published Date : Aug 01, 2010
Study Type : Animal Study
Additional Links
Additional Keywords : Environmental Pollutant
Problem Substances : Glyphosate, Roundup (herbicide)
[+]

Roundup is able to induce a dose-dependent formation of DNA adducts in the kidneys and liver of mice.Jan 01, 1998

Pubmed Data : Environ Mol Mutagen. 1998 ;31(1):55-9. PMID: 9464316
Article Published Date : Jan 01, 1998
Study Type : Animal Study
Additional Links
Diseases : DNA damage
Problem Substances : Roundup (herbicide)
Adverse Pharmacological Actions : Genotoxic
[+]

Roundup may interfere with spermatogenesis and impair fertility in male gonad.Apr 30, 2017

Pubmed Data : Exp Toxicol Pathol. 2017 May 1. Epub 2017 May 1. PMID: 28473188
Article Published Date : Apr 30, 2017
Study Type : Animal Study
Additional Links
Diseases : Infertility: Male
Problem Substances : Roundup (herbicide)
[+]

Study: Oral and intracheal toxicities of Roundup and its components.Jun 01, 1997

Pubmed Data : Vet Hum Toxicol. 1997 Jun;39(3):147-51. PMID: 9167243
Article Published Date : Jun 01, 1997
Study Type : Animal Study
Additional Links
Problem Substances : Glyphosate, Polyoxyethylene amine, Roundup (herbicide)
Adverse Pharmacological Actions : Cytotoxic
[+]

The glyphosate herbicide Roundup exhibits teratogenic potential in rats. Apr 30, 2003

Pubmed Data : Toxicol Lett. 2003 Apr 30;142(1-2):45-52. PMID: 12765238
Article Published Date : Apr 30, 2003
Study Type : Animal Study
Additional Links
Diseases : Prenatal Chemical Exposures
Problem Substances : Glyphosate, Roundup (herbicide)
Adverse Pharmacological Actions : Endocrine Disruptor, Teratogenic
[+]

The glyphosate-based formula Roundup sigificantly increases the bioaccumulation of mercury in water fleas.Nov 01, 2005

Pubmed Data : Environ Pollut. 2005 Nov;138(1):59-68. PMID: 15878796
Article Published Date : Nov 01, 2005
Study Type : Animal Study
Additional Links
Diseases : Mercury Poisoning
Problem Substances : Glyphosate, Roundup (herbicide)
Adverse Pharmacological Actions : Bioaccumulator
[+]

The herbicide Roundup may cause disorder in the morphophysiology of the male genital system of animals.Feb 01, 2007

Pubmed Data : Reprod Toxicol. 2007 Feb;23(2):182-91. Epub 2006 Nov 11. PMID: 17166697
Article Published Date : Feb 01, 2007
Study Type : Animal Study
Additional Links
Diseases : Endocrine Diseases, Hormonal Disorders: Children
Problem Substances : Glyphosate, Roundup (herbicide)
Adverse Pharmacological Actions : Endocrine Disruptor
[+]

These results reveal that melatonin is a protective agent against experimentally induced maternal and embryo toxicity from herbicides.Mar 31, 2017

Pubmed Data : Acta Histochem. 2017 Apr ;119(3):220-227. Epub 2017 Feb 13. PMID: 28202179
Article Published Date : Mar 31, 2017
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Herbicide Toxicity
Pharmacological Actions : Cytoprotective, Hepatoprotective
Problem Substances : Herbicide, Roundup (herbicide)
[+]

Ultra-low dose of Roundup herbicide non-alcoholic contributes to fatty liver disease in rats following chronic exposure.Jan 08, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2017 Jan 9 ;7:39328. Epub 2017 Jan 9. PMID: 28067231
Article Published Date : Jan 08, 2017
Study Type : Animal Study
Additional Links
Diseases : Nonalcoholic fatty liver disease (NAFLD)
Additional Keywords : glyphosate, glyphosate-based herbicides (GBH), Nonalcoholic fatty liver disease (NAFLD), Roundup (herbicide)
Problem Substances : Glyphosate, Roundup (herbicide)
Adverse Pharmacological Actions : Hepatotoxic
[+]

Roundup exposure may adversely affect human reproduction and fetal development in case of contamination. Jul 01, 2007

Pubmed Data : Arch Environ Contam Toxicol. 2007 Jul;53(1):126-33. Epub 2007 May 4. PMID: 17486286
Article Published Date : Jul 01, 2007
Study Type : In Vitro Study
Additional Links
Diseases : Endocrine Diseases, Prenatal Chemical Exposures
Problem Substances : Glyphosate, Roundup (herbicide)
Adverse Pharmacological Actions : Aromatase Disruptor, Endocrine Disruptor
[+]

"A glyphosate-based herbicide induces necrosis and apoptosis in mature rat testicular cells in vitro, and testosterone decrease at lower levels."Dec 19, 2011

Pubmed Data : Toxicol In Vitro. 2011 Dec 19. Epub 2011 Dec 19. PMID: 22200534
Article Published Date : Dec 19, 2011
Study Type : In Vitro Study
Additional Links
Diseases : Glyphosate Toxicity, Testosterone: Too Low
Problem Substances : Glyphosate, Roundup (herbicide)
Adverse Pharmacological Actions : Endocrine Disruptor: Testes
[+]

Agricultural practices that involve the use of herbicides such as Roundup affect non-target organisms and the water quality, modifying the structure and functionality of freshwater ecosystems.Apr 01, 2010

Pubmed Data : Ecotoxicology. 2010 Apr;19(4):710-21. Epub 2009 Nov 29. PMID: 20091117
Article Published Date : Apr 01, 2010
Study Type : Review
Additional Links
Problem Substances : Glyphosate, Roundup (herbicide)
[+]

Aronia berry concentrate at low doses restores the homeostatic redox environment of neurons treated with paraquat.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2016 ;2016:5296271. Epub 2015 Dec 6. PMID: 26770655
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Chokeberry
Diseases : Herbicide Toxicity
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Problem Substances : Herbicide, Paraquat
[+]

Comparative effects of the Roundup and glyphosate on mitochondrial oxidative phosphorylation.Nov 30, 2005

Pubmed Data : Chemosphere. 2005 Dec ;61(8):1115-22. Epub 2005 Apr 26. PMID: 16263381
Article Published Date : Nov 30, 2005
Study Type : In Vitro Study
Additional Links
Diseases : Mitochondrial Dysfunction
Additional Keywords : Drug Synergy
Problem Substances : Glyphosate formulations, Roundup (herbicide)
[+]

Glyphosate formulations induce apoptosis and necrosis in human umbilical, embryonic, and placental cells.Jan 01, 2009

Pubmed Data : Chem Res Toxicol. 2009 Jan;22(1):97-105. PMID: 19105591
Article Published Date : Jan 01, 2009
Study Type : In Vitro Study
Additional Links
Diseases : Prenatal Chemical Exposures
Problem Substances : Glyphosate, Glyphosate formulations, Roundup (herbicide)
Adverse Pharmacological Actions : Necrotic
[+]

Glyphosate herbicides may exhibit sublethal adverse effects on non-pest insects.Feb 01, 2010

Pubmed Data : Chemosphere. 2010 Feb;78(7):871-6. Epub 2009 Dec 16. PMID: 20018344
Article Published Date : Feb 01, 2010
Study Type : In Vitro Study
Additional Links
Additional Keywords : Environmental Pollutant
Problem Substances : Glyphosate, Roundup (herbicide)
[+]

Glyphosate pesticide (Roundup) exposure may adversely alter estrogen-related gene expression.Sep 01, 2007

Pubmed Data : Hum Exp Toxicol. 2007 Sep;26(9):747-52. PMID: 17984146
Article Published Date : Sep 01, 2007
Study Type : In Vitro Study
Additional Links
Diseases : Prenatal Chemical Exposures
Problem Substances : Glyphosate, Roundup (herbicide)
Adverse Pharmacological Actions : Endocrine Disruptor, Genotoxic
[+]

Glyphosate pesticides are cytotoxic to human peripheral blood mononuclear cells.Dec 01, 2007

Pubmed Data : Biomedica. 2007 Dec;27(4):594-604. PMID: 18320126
Article Published Date : Dec 01, 2007
Study Type : In Vitro Study
Additional Links
Problem Substances : Glyphosate, Roundup (herbicide)
Adverse Pharmacological Actions : Cytotoxic
[+]

Glyphosate suppresses the antagonistic effect of Enterococcus spp. on Clostridium botulinum.Feb 05, 2013

Pubmed Data : Anaerobe. 2013 Feb 6. Epub 2013 Feb 6. PMID: 23396248
Article Published Date : Feb 05, 2013
Study Type : In Vitro Study, Review
Additional Links
Diseases : Botulism, Botulism: Infantile
Problem Substances : Glyphosate, Glyphosate formulations, Roundup (herbicide)
Adverse Pharmacological Actions : Immunosuppressive
[+]

Glyphosate, hard water and nephrotoxic metals: are they the culprits behind the epidemic of chronic kidney disease of unknown etiology in sri lanka?Dec 31, 2013

Pubmed Data : Int J Environ Res Public Health. 2014 ;11(2):2125-47. Epub 2014 Feb 20. PMID: 24562182
Article Published Date : Dec 31, 2013
Study Type : Review
Additional Links
Diseases : Chronic Kidney Disease of Unknown Etiology (CKDu), Kidney Damage: Chemically-Induced, Kidney Diseases
Problem Substances : Glyphosate, Roundup (herbicide)
Adverse Pharmacological Actions : Nephrotoxic
[+]

Glyphosate-based herbicides are toxic and endocrine disruptors in human cell lines at exceedingly small concentrations (.5 ppm to 10 ppm).Aug 21, 2009

Pubmed Data : Toxicology. 2009 Aug 21;262(3):184-91. Epub 2009 Jun 17. PMID: 19539684
Article Published Date : Aug 21, 2009
Study Type : In Vitro Study
Additional Links
Diseases : DNA damage
Additional Keywords : Estrogen Receptor Beta
Problem Substances : Glyphosate, Roundup (herbicide)
Adverse Pharmacological Actions : Cytotoxic, Endocrine Disruptor, Mutagenic
[+]

Glyphosphate has a tumor-promoting effect in mouse skin. Mar 10, 2010

Pubmed Data : J Proteomics. 2010 Mar 10;73(5):951-64. Epub 2010 Jan 4. PMID: 20045496
Article Published Date : Mar 10, 2010
Study Type : In Vitro Study
Additional Links
Diseases : Skin Cancer
Problem Substances : Glyphosate, Roundup (herbicide)
Adverse Pharmacological Actions : Carcinogen
[+]

Roundup affects cell cycle regulation by delaying activation of the CDK1/cyclin B complex, by synergic effect of glyphosate and formulation products. Mar 01, 2002

Pubmed Data : Chem Res Toxicol. 2002 Mar ;15(3):326-31. PMID: 11896679
Article Published Date : Mar 01, 2002
Study Type : In Vitro Study
Additional Links
Problem Substances : Glyphosate, Roundup (herbicide)
Adverse Pharmacological Actions : Cytotoxic
[+]

Roundup and glyphosphate formulations exhibit toxicity by interfering with intracellular transport, and possibly intracellular Ca(2+) balance.Apr 01, 2010

Pubmed Data : Toxicol In Vitro. 2010 Apr;24(3):795-802. Epub 2009 Dec 29. PMID: 20036731
Article Published Date : Apr 01, 2010
Study Type : In Vitro Study
Additional Links
Problem Substances : Glyphosate, Roundup (herbicide)
[+]

Roundup contains compounds which exhibit significant toxicity to bacteria, microalgae, protozoa and crustaceans.Aug 01, 2003

Pubmed Data : Chemosphere. 2003 Aug;52(7):1189-97. PMID: 12821000
Article Published Date : Aug 01, 2003
Study Type : In Vitro Study
Additional Links
Additional Keywords : Environmental Pollutant
Problem Substances : Glyphosate, Isopropylamine (IPA), Polyoxyethylene amine, Roundup (herbicide)
Adverse Pharmacological Actions : Biocide
[+]

Roundup Disrupted Male Reproductive Functions By Triggering Calcium-Mediated Cell Death In Rat Testis And Sertoli Cells.Jun 28, 2013

Pubmed Data : Free Radic Biol Med. 2013 Jun 29. Epub 2013 Jun 29. PMID: 23820267
Article Published Date : Jun 28, 2013
Study Type : In Vitro Study
Additional Links
Diseases : Genital Diseases: Male, Infertility: Male, Oxidative Stress
Problem Substances : Glyphosate, Glyphosate formulations, Herbicide, Roundup
Adverse Pharmacological Actions : Glutathione Down-Regulation, Glutathione S-transferase Inducer (xenobiotic)
[+]

Roundup has a direct toxicological effect on freshwater microbial communities, dramatically altering the ratios of organisms found there.Dec 01, 2007

Pubmed Data : Ecol Appl. 2007 Dec;17(8):2310-22. PMID: 18213971
Article Published Date : Dec 01, 2007
Study Type : In Vitro Study
Additional Links
Additional Keywords : Environmental Pollutant
Problem Substances : Glyphosate, Roundup (herbicide)
[+]

Roundup herbicide and its active ingredient glyphosate isopropylamine is genotoxic. Jun 01, 1993

Pubmed Data : Mutat Res. 1993 Jun;300(1):29-36. PMID: 7683765
Article Published Date : Jun 01, 1993
Study Type : In Vitro Study
Additional Links
Problem Substances : Glyphosate, Isopropylamine (IPA), Roundup (herbicide)
Adverse Pharmacological Actions : Mutagenic
[+]

Roundup herbicide exhibits carcinogenic properties in a human skin cell line model. Dec 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Article Published Date : Dec 31, 2012
Study Type : In Vitro Study
Additional Links
Diseases : Skin Cancer
Problem Substances : Glyphosate, Glyphosate formulations, Roundup (herbicide)
Adverse Pharmacological Actions : Carcinogenic, Oxidant
[+]

Roundup herbicide is more toxic than its constituent parts and is genotoxic in concentrations that concentrations that correspond to a 450-fold dilution of spraying used in agriculture. Feb 14, 2012

Pubmed Data : Arch Toxicol. 2012 Feb 14. Epub 2012 Feb 14. PMID: 22331240
Article Published Date : Feb 14, 2012
Study Type : In Vitro Study
Additional Links
Diseases : Cancers: All, DNA damage
Problem Substances : Glyphosate, Roundup (herbicide)
Adverse Pharmacological Actions : Genotoxic
[+]

Roundup is a common herbicide that has been used in suicide due to its high level of toxicity. Jul 22, 2010

Pubmed Data : J Clin Neurosci. 2010 Jul 22. Epub 2010 Jul 22. PMID: 20655231
Article Published Date : Jul 22, 2010
Study Type : Commentary
Additional Links
Problem Substances : Glyphosate, Isopropylamine (IPA), Polyoxyethylene amine, Roundup (herbicide)
[+]

The chemical constituents of Roundup exhibit non-selective toxicity to a wide range of aquatic microphotoautotrophs, cyanobacteria and eukaryotic algae.Aug 31, 2010

Pubmed Data : Ecotoxicol Environ Saf. 2010 Aug 31. Epub 2010 Aug 31. PMID: 20813408
Article Published Date : Aug 31, 2010
Study Type : In Vitro Study
Additional Links
Additional Keywords : Environmental Pollutant
Problem Substances : Glyphosate, Isopropylamine (IPA), Roundup (herbicide)
[+]

There is evidence indicating that Roundup is not superior to other pesticides in reducing environmental contamination and may represent a significant persistent pollutant. Mar 01, 2008

Pubmed Data : Pest Manag Sci. 2008 Mar;64(3):262-75. PMID: 18205189
Article Published Date : Mar 01, 2008
Study Type : In Vitro Study
Additional Links
Additional Keywords : Environmental Pollutant
Problem Substances : Glyphosate, Roundup (herbicide)
[+]

There is evidence that a glyphosate (Roundup) herbicide metabolite persists in the environment as a toxic pollutant. Oct 01, 2010

Pubmed Data : Environ Pollut. 2010 Oct;158(10):3172-8. Epub 2010 Aug 6. PMID: 20691521
Article Published Date : Oct 01, 2010
Study Type : Commentary
Additional Links
Additional Keywords : Environmental Pollutant
Problem Substances : Glyphosate, Roundup (herbicide)

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