Insulin

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37 Diseases Researched for Insulin
NameACCKFocus
Diabetes Mellitus: Type 1: Prevention432Locked
Diabetes Mellitus: Type 2432Locked
Insulin Resistance322Locked
Cancers: All321Locked
Celiac Disease321Locked
High Cholesterol220Locked
Kidney Cancer120Locked
Liver Cancer120Locked
Lung Cancer120Locked
Pancreatic Cancer120Locked
Respiratory Cancers120Locked
Stomach Cancer120Locked
Hyperinsulinism517Locked
Diabetes Mellitus: Type 1413Locked
Hyperglycemia212Locked
All-Cause Mortality110Locked
Breastfeeding Concerns: Chemical Exposure110Locked
Cardiovascular Diseases110Locked
Diabetes: Cancer Risk110Locked
Diabetes: Cardiovascular Illness110Locked
Heart Disease: Ischemic110Locked
Myocardial Ischemia110Locked
Polycystic Ovary Syndrome110Locked
Statin-Induced Pathologies110Locked
Fatty Liver24Locked
Triglycerides: Elevated24Locked
Acne22Locked
Aging: Brain 12Locked
Atherosclerosis12Locked
Fructose-Induced Toxicity 12Locked
Hypertension12Locked
Inflammation12Locked
Liver Damage12Locked
Liver Stress: Fructose-Induced12Locked
Myopia12Locked
Weight Problems12Locked
Insulin: Elevated11Locked
9 Adverse Pharmacological Actions Researched for Insulin
NameACCKFocus
Carcinogenic120Locked
Carcinogenic (suspected)110Locked
Endocrine Disruptor: Insulin Resistance110Locked
Dyslipidemic12Locked
Gluconeogenesis Up-Regulation12Locked
Inflammatory12Locked
Lipogenesis Up-Regulation12Locked
Myopiagenic 12Locked
Insulinotropic11Locked
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View the Evidence:
68 Abstracts with Insulin Research

[+]

Meta-analysis: The use of insulin and insulin analogs increase the risk of various cancers.Oct 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Curr Drug Saf. 2013 Nov ;8(5):333-48. PMID: 24215311
Article Published Date : Oct 31, 2013
Study Type : Meta Analysis
Additional Links
Diseases : Kidney Cancer, Liver Cancer, Lung Cancer, Pancreatic Cancer, Respiratory Cancers, Stomach Cancer
Problem Substances : Insulin
Adverse Pharmacological Actions : Carcinogenic
[+]

"A Palaeolithic diet improves glucose tolerance more than a Mediterranean-like diet in individuals with ischaemic heart disease."Sep 01, 2007

Pubmed Data : Diabetologia. 2007 Sep ;50(9):1795-807. Epub 2007 Jun 22. PMID: 17583796
Article Published Date : Sep 01, 2007
Study Type : Human Study
Additional Links
Diseases : Diabetes Mellitus: Type 2, Heart Disease: Ischemic, Myocardial Ischemia
Therapeutic Actions : Dietary Modification: Paleolithic/Stone Age Diet
Problem Substances : Insulin
[+]

A glutenfree diet showed short-term benefits by reducing GI symptoms and severe hypoglycaemia in T1D and CDMay 31, 2011

Pubmed Data : Pediatr Diabetes. 2011 Jun ;12(4 Pt 1):322-5. Epub 2011 Mar 29. PMID: 21615651
Article Published Date : May 31, 2011
Study Type : Human Study
Additional Links
Diseases : Celiac Disease, Diabetes Mellitus: Type 1: Prevention
Additional Keywords : Autoantibodies, Body Mass Index (BMI), Glycosylated Haemoglobin (HbA1c), Hypoglycemia
Problem Substances : Gluten, Insulin
[+]

A nutraceutical formula containing berberine, chlorogenic acid, and tocotrienols was found to improve a large number of metabolic and liver parameters in overweight subjects.Mar 28, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr J. 2015 Mar 28 ;14:30. Epub 2015 Mar 28. PMID: 25886384
Article Published Date : Mar 28, 2015
Study Type : Human Study
Additional Links
Substances : Berberine, Chlorogenic Acid, Tocotrienols
Diseases : Fatty Liver, Hyperlipidemia, Insulin Resistance
Problem Substances : Insulin
[+]

Acute epigallocatechin-3-gallate supplementation delays gastric emptying in healthy women.Aug 20, 2018

Pubmed Data : Nutrients. 2018 Aug 20 ;10(8). Epub 2018 Aug 20. PMID: 30127247
Article Published Date : Aug 20, 2018
Study Type : Human Study
Additional Links
Substances : Catechin
Diseases : Adiponectin: Low Levels
Pharmacological Actions : Adiponectin upregulation
Problem Substances : Insulin
[+]

Atorvastatin causes insulin resistance and increases ambient glycemia in hypercholesterolemic patientsMar 23, 2010

Pubmed Data : J Am Coll Cardiol. 2010 Mar 23 ;55(12):1209-16. PMID: 20298928
Article Published Date : Mar 23, 2010
Study Type : Human Study
Additional Links
Diseases : High Cholesterol, Hyperglycemia, Insulin Resistance, Statin-Induced Pathologies
Problem Substances : Atorvastatin, Insulin , Statin Drugs
Adverse Pharmacological Actions : Endocrine Disruptor: Insulin Resistance
[+]

Current guides for medical treatment suggest that insulin does not pass into milk, which is untrue.Jan 01, 2012

Pubmed Data : Int J Endocrinol. 2012 ;2012:296368. Epub 2012 Mar 5. PMID: 22500167
Article Published Date : Jan 01, 2012
Study Type : Human Study
Additional Links
Diseases : Breastfeeding Concerns: Chemical Exposure
Problem Substances : Insulin
[+]

Daily consumption of one egg may reduce the risk of diabetes without any adverse effects on lipid profiles in individuals with pre- and type II diabetes.Aug 14, 2018

Pubmed Data : Food Funct. 2018 Aug 15 ;9(8):4469-4479. PMID: 30073224
Article Published Date : Aug 14, 2018
Study Type : Human Study
Additional Links
Substances : Egg
Diseases : Diabetes Mellitus: Type 2, Insulin Resistance, Prediabetes
Pharmacological Actions : Hypoglycemic Agents
Additional Keywords : Risk Reduction
Problem Substances : Insulin
[+]

Flaxseed fiber suppresses postprandial lipemia and appetite in healthy young men.Feb 01, 2013

Pubmed Data : Nutr Metab Cardiovasc Dis. 2013 Feb ;23(2):136-43. Epub 2011 Jul 29. PMID: 21802266
Article Published Date : Feb 01, 2013
Study Type : Human Study
Additional Links
Substances : Fiber, Flaxseed
Diseases : Hyperlipidemia
Pharmacological Actions : Antilipemic Agents, Appetite Suppresant
Problem Substances : Insulin
[+]

Four grams of high molecular weight oat β-glucan lowers appetite but not ad libitum eating and beneficially modulates postprandial glycemia.Jan 01, 2018

Pubmed Data : Appetite. 2018 09 1 ;128:197-204. Epub 2018 Jun 18. PMID: 29920323
Article Published Date : Jan 01, 2018
Study Type : Human Study
Additional Links
Substances : Beta-glucan
Diseases : Hyperglycemia, Hyperinsulinism
Pharmacological Actions : Hypoglycemic Agents
Problem Substances : Insulin
[+]

Girls with PCOS and IR more hirsute, more AN, lower SHBG and higher fasting insulin levelsMay 31, 2010

Pubmed Data : J Pediatr Adolesc Gynecol. 2010 Jun ;23(3):158-61. Epub 2009 Dec 5. PMID: 19963413
Article Published Date : May 31, 2010
Study Type : Human Study
Additional Links
Diseases : Insulin Resistance, Polycystic Ovary Syndrome
Problem Substances : Insulin
[+]

Green tea extract decreased fasting insulin concentrations in those with elevated baseline fasting concentrations.Jan 01, 2016

Pubmed Data : J Nutr. 2016 Jan ;146(1):38-45. Epub 2015 Nov 18. PMID: 26581683
Article Published Date : Jan 01, 2016
Study Type : Human Study
Additional Links
Substances : Catechin , Polyphenols, Tea
Diseases : Adiponectin: Low Levels, Obesity
Therapeutic Actions : Fasting/Caloric Restriction
Additional Keywords : Plant Extracts
Problem Substances : Insulin
[+]

Higher egg intake was associated with a lower risk of T2D in this cohort of middle-aged and older men.Apr 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Clin Nutr. 2015 May ;101(5):1088-96. Epub 2015 Apr 1. PMID: 25832339
Article Published Date : Apr 30, 2015
Study Type : Human Study
Additional Links
Substances : Egg
Diseases : Diabetes Mellitus: Type 2
Additional Keywords : Risk Reduction
Problem Substances : Insulin
[+]

Hypocaloric, plant-based short-term dietary oatmeal interventions significantly reduced mean blood glucose levels and mean required daily insulin doses in a critically ill and septic patient in the intensive care unit.Oct 01, 2019

Pubmed Data : Complement Ther Med. 2019 Oct ;46:69-72. Epub 2019 Jul 30. PMID: 31519290
Article Published Date : Oct 01, 2019
Study Type : Human Study
Additional Links
Substances : Oats
Diseases : Insulin Resistance
Pharmacological Actions : Insulin Sensitizers
Problem Substances : Insulin
[+]

In this uncontrolled pilot study, hospital admission and diabetes adapted diet followed by oatmeal intervention achieved a approximately 40% reduction of insulin dosage required to achieve controlled glucose levels.Feb 01, 2008

Pubmed Data : Exp Clin Endocrinol Diabetes. 2008 Feb ;116(2):132-4. Epub 2007 Dec 20. PMID: 18095234
Article Published Date : Feb 01, 2008
Study Type : Human Study
Additional Links
Diseases : Adiponectin: Low Levels, Diabetes Mellitus: Type 2, Insulin Resistance
Pharmacological Actions : Insulin Sensitizers
Problem Substances : Insulin
[+]

Including indigestible carbohydrates in the evening meal of healthy subjects improves glucose tolerance, lowers inflammatory markers, and increases satiety after a subsequent standardized breakfast.Apr 01, 2008

Pubmed Data : J Nutr. 2008 Apr ;138(4):732-9. PMID: 18356328
Article Published Date : Apr 01, 2008
Study Type : Human Study
Additional Links
Substances : Fiber
Diseases : Adiponectin: Low Levels, Inflammation, Insulin Resistance
Pharmacological Actions : Adiponectin upregulation, Interleukin-6 Downregulation
Problem Substances : Insulin
[+]

Increasing nutritional fiber results in reduced serum ZO levels, reduced liver enzymes and improved hepatic steatosis in patients with NAFLDNov 17, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2018 Nov 18 ;10(11). Epub 2018 Nov 18. PMID: 30453660
Article Published Date : Nov 17, 2018
Study Type : Human Study
Additional Links
Substances : Fiber
Diseases : Insulin Resistance, Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Gastroprotective
Problem Substances : Insulin
[+]

Insulin use is associated with increased pancreatic cancer risk in the short-term in diabetics.Jul 22, 2014

Pubmed Data : Ann Oncol. 2014 Jul 23. Epub 2014 Jul 23. PMID: 25057164
Article Published Date : Jul 22, 2014
Study Type : Human Study
Additional Links
Diseases : Diabetes: Cancer Risk
Problem Substances : Insulin
Adverse Pharmacological Actions : Carcinogenic (suspected)
[+]

Insulin-free whey-based cow's milk formula is associated with lower incidence of beta cell autoimmunity in infants and young children.. Mar 05, 2012

Pubmed Data : Arch Pediatr Adolesc Med. 2012 Mar 5. Epub 2012 Mar 5. PMID: 22393174
Article Published Date : Mar 05, 2012
Study Type : Human Study
Additional Links
Diseases : Diabetes Mellitus: Type 1
Problem Substances : Cow Milk, Insulin
[+]

Oatmeal diet days may improve insulin resistance in patients with type 2 diabetes mellitus.Jan 01, 2013

Pubmed Data : Forsch Komplementmed. 2013 ;20(6):465-8. Epub 2013 Dec 13. PMID: 24434762
Article Published Date : Jan 01, 2013
Study Type : Human Study
Additional Links
Substances : Oats
Diseases : Diabetes Mellitus: Type 2, Insulin Resistance, Obesity
Problem Substances : Insulin
[+]

Orange pomace fiber lowers postprandial glycemic and insulinemic responses in men with increased cardiometabolic risk.Jan 01, 2016

Pubmed Data : J Nutr. 2016 06 ;146(6):1197-203. Epub 2016 May 11. PMID: 27170728
Article Published Date : Jan 01, 2016
Study Type : Human Study
Additional Links
Substances : Fiber
Diseases : Cardiovascular Diseases, Hyperglycemia, Hyperinsulinism
Pharmacological Actions : Hypoglycemic Agents
Problem Substances : Insulin
[+]

Patients with type 2 diabetes who use sulfonylureas or insulin have an increased risk for cancer-related mortality. Feb 01, 2006

Pubmed Data : Diabetes Care. 2006 Feb;29(2):254-8. PMID: 16443869
Article Published Date : Feb 01, 2006
Study Type : Human Study
Additional Links
Diseases : Cancers: All, Diabetes Mellitus: Type 2
Additional Keywords : Drug: Metformin
Problem Substances : Glipizide, Glyburide, Insulin , Metformin , Sulfonylureas
[+]

Postmeal fluctuations in blood glucose and insulin induced by sucrose are alleviated when sucrose is consumed with blackcurrants or lingonberries. Aug 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Clin Nutr. 2012 Sep ;96(3):527-33. Epub 2012 Aug 1. PMID: 22854401
Article Published Date : Aug 31, 2012
Study Type : Human Study
Additional Links
Substances : Black Currant, Lingonberry
Diseases : Hyperinsulinism
Pharmacological Actions : Glucose Uptake Optimization
Additional Keywords : Metabolic Regulation
Problem Substances : Insulin , Sucrose
[+]

Resveratrol improves insulin resistance, glucose and lipid metabolism in patients with non-alcoholic fatty liver disease.Mar 01, 2015

Pubmed Data : Dig Liver Dis. 2015 Mar ;47(3):226-32. Epub 2014 Dec 16. PMID: 25577300
Article Published Date : Mar 01, 2015
Study Type : Human Study
Additional Links
Substances : Resveratrol, Stilbenes
Diseases : Insulin Resistance
Pharmacological Actions : Adiponectin upregulation, Anti-Inflammatory Agents, Anticholesteremic Agents, Hypoglycemic Agents, Insulin Sensitizers
Problem Substances : Insulin
[+]

Supplementation of a gamma-tocopherol-rich mixture of tocopherols in healthy men protects against vascular endothelial dysfunction.Dec 31, 2012

Pubmed Data : J Nutr Biochem. 2013 Jan ;24(1):196-203. Epub 2012 Jul 25. PMID: 22841396
Article Published Date : Dec 31, 2012
Study Type : Human Study
Additional Links
Substances : Arginine, Vitamin C, Vitamin E, Vitamin E: Gamma-Tocopherol
Diseases : Endothelial Dysfunction, Hyperglycemia, Oxidative Stress
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation
Problem Substances : Insulin
[+]

T-cell response to insulin peptide A1-12 enhanced in clinical and preclinical T1D associated with high-risk HLA-genotypeAug 31, 2008

Pubmed Data : J Autoimmun. 2008 Sep ;31(2):142-8. Epub 2008 Jun 18. PMID: 18565729
Article Published Date : Aug 31, 2008
Study Type : Human Study
Additional Links
Diseases : Diabetes Mellitus: Type 1: Prevention
Additional Keywords : HLA Genotypes
Problem Substances : Insulin
[+]

The addition of beta glucan to a meal slows the appearance of glucose in plasma, resulting in longer-lasting insulin secretion which exerts a prolonged inhibition of endogenous glucose production and lipolysis.Mar 01, 2009

Pubmed Data : Mol Nutr Food Res. 2009 Mar ;53(3):361-9. PMID: 18837470
Article Published Date : Mar 01, 2009
Study Type : Human Study
Additional Links
Substances : Beta-glucan, Fiber
Pharmacological Actions : Insulin Sensitizers
Problem Substances : Insulin
[+]

There may be an association between increasing exogenous insulin dose and increased risk of all-cause mortality.Mar 31, 2015

Pubmed Data : Diabetes Obes Metab. 2015 Apr ;17(4):350-62. Epub 2014 Dec 10. PMID: 25399739
Article Published Date : Mar 31, 2015
Study Type : Human Study
Additional Links
Diseases : All-Cause Mortality, Cancers: All, Cardiovascular Diseases, Diabetes: Cardiovascular Illness, Diabetes Mellitus: Type 2
Additional Keywords : Increased Risk
Problem Substances : Insulin
[+]

This study found that that taking green tea, capsaicin and ginger co-supplements for 8 weeks among overweight women had beneficial effects on weight, BMI, markers of insulin metabolism and plasma glutathione levels.Jan 01, 2017

Pubmed Data : Ann Nutr Metab. 2017 ;70(4):277-285. Epub 2017 Jun 9. PMID: 28595182
Article Published Date : Jan 01, 2017
Study Type : Human Study
Additional Links
Substances : Capsaicin, Ginger, Green Tea, Tea
Diseases : Insulin Resistance, Obesity, Oxidative Stress
Pharmacological Actions : Antioxidant Effects, Insulin Sensitizers
Additional Keywords : Plant Extracts
Problem Substances : Insulin
[+]

Whole grains reduce postprandial insulin and triglyceride responses.Aug 01, 2014

Pubmed Data : Nutr Metab Cardiovasc Dis. 2014 Aug ;24(8):837-44. Epub 2014 Jan 28. PMID: 24598599
Article Published Date : Aug 01, 2014
Study Type : Human Study
Additional Links
Diseases : Cardiovascular Diseases, Diabetes Mellitus: Type 2, Metabolic Diseases
Problem Substances : Insulin
[+]

Extremely low frequency electromagnetic fields downregulate insulin secretion.Jun 24, 2005

Pubmed Data : Biochem Biophys Res Commun. 2005 Jun 24 ;332(1):28-32. PMID: 15896294
Article Published Date : Jun 24, 2005
Study Type : Human In Vitro
Additional Links
Diseases : Radiation Induced Illness
Anti Therapeutic Actions : Electromagnetic Field Harms, Electromagnetic Radiation
Problem Substances : Insulin
[+]

Resveratrol could be a prime candidate in ameliorating dysfunctioning adipose tissue induced by inflammatory stimulation.Jan 01, 2016

Pubmed Data : PLoS One. 2016 ;11(7):e0159747. Epub 2016 Jul 20. PMID: 27438462
Article Published Date : Jan 01, 2016
Study Type : Human In Vitro
Additional Links
Substances : Resveratrol, Stilbenes
Diseases : Inflammation, Insulin Resistance, Lipopolysaccharide-Induced Toxicity, Obesity
Pharmacological Actions : Anti-Inflammatory Agents
Problem Substances : Insulin
[+]

"Brain insulin impairs amyloid-beta(1-40) clearance from the brain."Oct 26, 2004

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Neurosci. 2004 Oct 27 ;24(43):9632-7. PMID: 15509750
Article Published Date : Oct 26, 2004
Study Type : Animal Study
Additional Links
Diseases : Aging: Brain , Hyperinsulinism
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Insulin
[+]

"Hypothalamic orexin stimulates feeding-associated glucose utilization in skeletal muscle via sympathetic nervous system."Nov 30, 2009

Pubmed Data : Cell Metab. 2009 Dec ;10(6):466-80. PMID: 19945404
Article Published Date : Nov 30, 2009
Study Type : Animal Study
Additional Links
Problem Substances : Insulin
[+]

A high fructose diet may contribute to the development of fatty liver, gluconeogenesis up-regulation and inflammation. May 01, 2010

Pubmed Data : Endocrinology. 2010 May;151(5):2040-9. Epub 2010 Mar 8. PMID: 20211973
Article Published Date : May 01, 2010
Study Type : Animal Study
Additional Links
Diseases : Fatty Liver, Fructose-Induced Toxicity , Hyperglycemia, Inflammation, Liver Stress: Fructose-Induced, Triglycerides: Elevated
Problem Substances : Insulin
Adverse Pharmacological Actions : Dyslipidemic, Gluconeogenesis Up-Regulation, Inflammatory, Lipogenesis Up-Regulation
[+]

An aqueous extract of white tea is effective to reduce most of the diabetes associated abnormalities in a steptozotocin-induced diabetes model of rats.Dec 14, 2011

Pubmed Data : Phytomedicine. 2011 Dec 15 ;19(1):25-31. Epub 2011 Jul 30. PMID: 21802923
Article Published Date : Dec 14, 2011
Study Type : Animal Study
Additional Links
Substances : White Tea
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Anticholesteremic Agents, Antioxidants, Hypoglycemic Agents
Additional Keywords : Phytotherapy, Plant Extracts
Problem Substances : Insulin
[+]

Anti-diabetic activity of Zingiber officinale in streptozotocin-induced type I diabetic rats.Dec 31, 2003

Pubmed Data : J Pharm Pharmacol. 2004 Jan ;56(1):101-5. PMID: 14980006
Article Published Date : Dec 31, 2003
Study Type : Animal Study
Additional Links
Substances : Ginger
Diseases : Diabetes Mellitus: Type 1: Prevention, Hypertension
Pharmacological Actions : Hypoglycemic Agents, Insulin-releasing
Additional Keywords : Phytotherapy
Problem Substances : Insulin
[+]

Beta-glucan and mulberry have synergistic effects on metabolic disorders.Oct 12, 2017

Pubmed Data : Nutrients. 2017 Oct 12 ;9(10). Epub 2017 Oct 12. PMID: 29023387
Article Published Date : Oct 12, 2017
Study Type : Animal Study
Additional Links
Substances : Beta-glucan, Mulberry
Diseases : Insulin Resistance, Obesity, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hypoglycemic Agents
Additional Keywords : Drug Synergy, Plant Extracts
Problem Substances : Insulin
[+]

Blueberry and mulberry juice prevent obesity development in C57BL/6 mice.Dec 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2013 ;8(10):e77585. Epub 2013 Oct 15. PMID: 24143244
Article Published Date : Dec 31, 2012
Study Type : Animal Study
Additional Links
Substances : Blueberry, Mulberry
Diseases : Obesity
Pharmacological Actions : Anticholesteremic Agents
Additional Keywords : Anti-Obesity Agents
Problem Substances : Insulin
[+]

Camel milk inhibits the diabetes-induced elevation in incretin hormones, TNF-α and TGF-β1 levels.May 31, 2014

Pubmed Data : Horm Metab Res. 2014 Jun ;46(6):404-11. Epub 2014 Mar 13. PMID: 24627103
Article Published Date : May 31, 2014
Study Type : Animal Study
Additional Links
Substances : Camel Milk
Diseases : Atherosclerosis, Diabetes Mellitus: Type 2, Insulin Resistance
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Anti-Inflammatory Agents, Hypoglycemic Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Insulin
[+]

Dietary catechins lower blood glucose levels, mitigate oxidative stress, and inhibit the angiotension-converting enzyme.Dec 01, 2007

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 2007 Dec ;53(6):496-500. PMID: 18202537
Article Published Date : Dec 01, 2007
Study Type : Animal Study
Additional Links
Substances : Catechin , Tea
Diseases : Hypertension, Oxidative Stress
Pharmacological Actions : Antihypertensive Agents, Antioxidant Effects, Hypoglycemic Agents
Problem Substances : Insulin
[+]

Flower and inflorescence stalk of M. balbisiana Colla. possess significant antidiabetic, antihyperlipidemic, and antioxidant activities.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Indian J Pharmacol. 2017 Jan-Feb;49(1):71-76. PMID: 28458426
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Banana
Diseases : Diabetes Mellitus: Type 1: Prevention
Pharmacological Actions : Antioxidants, Hypoglycemic Agents
Additional Keywords : Plant Extracts
Problem Substances : Insulin
[+]

Grape seed extract prevents adverse metabolic alterations through tis anti-inflammatory and antioxidant action.Oct 01, 2017

Pubmed Data : Phytother Res. 2017 Oct ;31(10):1621-1632. Epub 2017 Aug 25. PMID: 28840618
Article Published Date : Oct 01, 2017
Study Type : Animal Study
Additional Links
Substances : Anthocyanins, Polyphenols
Diseases : Adiponectin: Low Levels, Inflammation, Insulin Resistance, Obesity, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
Problem Substances : Insulin
[+]

Insulin may contribute to myopia. Jan 01, 2009

Pubmed Data : Invest Ophthalmol Vis Sci. 2009 Jan;50(1):13-23. Epub 2008 Jul 3. PMID: 18599564
Article Published Date : Jan 01, 2009
Study Type : Animal Study
Additional Links
Diseases : Hyperinsulinism, Myopia
Additional Keywords : Diseases that are Linked
Problem Substances : Insulin
Adverse Pharmacological Actions : Myopiagenic
[+]

Mate tea reduces high fat diet-induced liver and metabolic disorders in mice.Jan 01, 2019

Pubmed Data : Biomed Pharmacother. 2019 Jan ;109:1547-1555. Epub 2018 Nov 14. PMID: 30551407
Article Published Date : Jan 01, 2019
Study Type : Animal Study
Additional Links
Substances : Tea
Diseases : Fatty Liver, Inflammation, Insulin Resistance, Lipid Peroxidation, Obesity, Oxidative Stress
Additional Keywords : Plant Extracts
Problem Substances : Insulin
[+]

Meal-anticipatory glucagon-like peptide-1 secretion in rats.Jan 31, 2010

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Endocrinology. 2010 Feb ;151(2):569-75. Epub 2009 Nov 13. PMID: 19915164
Article Published Date : Jan 31, 2010
Study Type : Animal Study
Additional Links
Pharmacological Actions : Glucagon Like peptide 1 (GLP-1) Up-regulation
Additional Keywords : Food-anticipatory
Problem Substances : Insulin
[+]

Monosodium glutamate induces fatty liver, insulin and triglyceride elevations, increased weight gain and adverse liver changes.Aug 01, 2009

Pubmed Data : J Lipid Res. 2009 Aug;50(8):1521-37. Epub 2008 Nov 11. PMID: 19001666
Article Published Date : Aug 01, 2009
Study Type : Animal Study
Additional Links
Diseases : Fatty Liver, Hyperinsulinism, Liver Damage, Triglycerides: Elevated, Weight Problems
Problem Substances : Insulin , Monosodium Glutamate (MSG), Trans Fatty Acids
[+]

Nigella sativa exerts lipid-lowering and insulin-sensitizing actions in the rat.Sep 30, 2004

Pubmed Data : J Ethnopharmacol. 2004 Oct ;94(2-3):251-9. PMID: 15325727
Article Published Date : Sep 30, 2004
Study Type : Animal Study
Additional Links
Substances : Nigella sativa (aka Black Seed)
Diseases : Hyperlipidemia, Insulin Resistance
Pharmacological Actions : Hypolipidemic, Insulin Sensitizers
Additional Keywords : Plant Extracts
Problem Substances : Insulin
[+]

P. alata has anti-inflammatory properties, contributing to the protection of beta cells in pancreatic islets in NOD mice.May 31, 2016

Pubmed Data : Int Immunopharmacol. 2016 Jun ;35:127-136. Epub 2016 Apr 16. PMID: 27039211
Article Published Date : May 31, 2016
Study Type : Animal Study
Additional Links
Substances : Passion Flower
Diseases : Diabetes Mellitus: Type 1: Prevention, Lipid Peroxidation
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Pancreato Protective Agents
Additional Keywords : Plant Extracts
Problem Substances : Insulin
[+]

Phloretin might be able to increase insulin sensitivity and alleviate the metabolic diseases.Nov 30, 2014

Pubmed Data : J Nutr Biochem. 2014 Dec ;25(12):1296-308. Epub 2014 Sep 16. PMID: 25283330
Article Published Date : Nov 30, 2014
Study Type : Animal Study
Additional Links
Substances : Phloretin
Diseases : Insulin Resistance
Pharmacological Actions : Insulin Sensitizers
Problem Substances : Insulin
[+]

Purified betacyanins from Hylocereus undatus peel ameliorate obesity and insulin resistance in high-fat-diet-fed mice.Jan 12, 2016

Pubmed Data : J Agric Food Chem. 2016 Jan 13 ;64(1):236-44. Epub 2015 Dec 24. PMID: 26653843
Article Published Date : Jan 12, 2016
Study Type : Animal Study
Additional Links
Substances : Dragon Fruit
Diseases : High Fat Diet, Insulin Resistance, Obesity
Additional Keywords : Anti-Obesity Agents, Gene Expression Regulation, Plant Extracts
Problem Substances : Insulin
[+]

Quercetin could potentially be used to ameliorate myocardial damage due to oxidative stress, inflammation and apoptosis in diabetes.Jan 31, 2017

Pubmed Data : Biomed Pharmacother. 2017 Feb ;86:570-582. Epub 2016 Dec 24. PMID: 28027533
Article Published Date : Jan 31, 2017
Study Type : Animal Study
Additional Links
Substances : Quercetin
Diseases : Diabetic Complications, Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Cardioprotective
Problem Substances : Insulin
[+]

Rats may have a diabetic-like response to magnetic fields.Dec 01, 1991

Pubmed Data : Invest Radiol. 1991 Dec ;26(12):1095-100. PMID: 1765445
Article Published Date : Dec 01, 1991
Study Type : Animal Study
Additional Links
Diseases : Diabetes Mellitus: Type 2
Anti Therapeutic Actions : Electromagnetic Field Harms, Electromagnetic Radiation
Problem Substances : Insulin
[+]

Rats may have a diabetic-like response to magnetic fields.Dec 01, 1991

Pubmed Data : Invest Radiol. 1991 Dec ;26(12):1095-100. PMID: 1765445
Article Published Date : Dec 01, 1991
Study Type : Animal Study
Additional Links
Diseases : Diabetes Mellitus: Type 2
Anti Therapeutic Actions : Electromagnetic Field Harms, Electromagnetic Radiation
Problem Substances : Insulin
[+]

Resveratrol alleviates ethanol-induced hormonal and metabolic disturbances in the rat.Jan 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Physiol Res. 2017 03 31 ;66(1):135-145. Epub 2016 Oct 26. PMID: 27782737
Article Published Date : Jan 31, 2017
Study Type : Animal Study
Additional Links
Substances : Resveratrol, Stilbenes
Diseases : Adiponectin: Low Levels, Alcohol Toxicity
Problem Substances : Insulin
[+]

Starch and β-glucan in a whole grain-like structural form have the potential as a dietary strategy to combat obesity-induced hepatic insulin resistance for improved health.Aug 01, 2019

Pubmed Data : Food Funct. 2019 Aug 1 ;10(8):5091-5101. Epub 2019 Jul 31. PMID: 31363728
Article Published Date : Aug 01, 2019
Study Type : Animal Study
Additional Links
Substances : Beta-glucan
Diseases : Insulin Resistance, Obesity
Pharmacological Actions : Inhibitor of Nuclear Factor Kappa-B Kinase (IKK), Insulin Sensitizers, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Insulin
[+]

Sulforaphane is a promising agent to restore glucose tolerance through upregulation of insulin signaling in obese mice.Sep 19, 2018

Pubmed Data : Food Funct. 2018 Sep 19 ;9(9):4695-4701. PMID: 30091431
Article Published Date : Sep 19, 2018
Study Type : Animal Study
Additional Links
Substances : Sulforaphane
Diseases : Insulin Resistance
Pharmacological Actions : Glucose Uptake Optimization, Insulin Sensitizers
Additional Keywords : Broccoli, Broccoli Sprouts, Cruciferous Vegetables, Isothiocyanates
Problem Substances : Insulin
[+]

These results show that chronic consumption of β-glucans can improve glucose control and decrease fatty liver in a model of diabetes with obesity.Oct 01, 2013

Pubmed Data : Eur J Nutr. 2013 Oct ;52(7):1743-53. Epub 2012 Dec 11. PMID: 23229409
Article Published Date : Oct 01, 2013
Study Type : Animal Study
Additional Links
Substances : Beta-glucan, Fiber
Diseases : Adiponectin: Low Levels, Diabetes Mellitus: Type 2, Fatty Liver, Insulin Resistance, Obesity
Pharmacological Actions : Adiponectin upregulation, Antioxidant
Problem Substances : Insulin
[+]

Tocotrienol-rich fraction supplementation reduces hyperglycemia-induced skeletal muscle damage through regulation of insulin signaling and oxidative stress in type 2 diabetic mice.Jan 01, 2018

Pubmed Data : J Nutr Biochem. 2018 07 ;57:77-85. Epub 2018 Mar 21. PMID: 29679925
Article Published Date : Jan 01, 2018
Study Type : Animal Study
Additional Links
Substances : Tocotrienols
Diseases : Diabetes Mellitus: Type 2, Oxidative Stress
Pharmacological Actions : Antioxidant, Insulin Sensitizers
Problem Substances : Insulin
[+]

Treatments with lotus seedpod oligomeric procyanidins could be beneficial in diabetic treatments.May 16, 2017

Pubmed Data : J Agric Food Chem. 2017 May 17 ;65(19):3801-3810. Epub 2017 May 8. PMID: 28314100
Article Published Date : May 16, 2017
Study Type : Animal Study
Additional Links
Substances : Lotus
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Hypoglycemic Agents, Hypolipidemic
Additional Keywords : Plant Extracts, Proanthocyanidins
Problem Substances : Insulin
[+]

"Over-stimulation of insulin/IGF-1 signaling by western diet may promote diseases of civilization."Jan 01, 2011

Pubmed Data : Nutr Metab (Lond). 2011 ;8:41. Epub 2011 Jun 24. PMID: 21699736
Article Published Date : Jan 01, 2011
Study Type : Review
Additional Links
Diseases : Acne, Cancers: All, Diabetes Mellitus: Type 1, Hyperinsulinism, Insulin: Elevated
Anti Therapeutic Actions : Western Diet
Problem Substances : Cow Milk, Insulin
Adverse Pharmacological Actions : Insulinotropic
[+]

Acne development and androgen level changes due to high glycemic loads affecting serum insulin and insulin-like growth factor-1 levels.Oct 31, 2010

Pubmed Data : Clin Dermatol. 2010 Nov-Dec;28(6):598-604. PMID: 21034984
Article Published Date : Oct 31, 2010
Study Type : Review
Additional Links
Diseases : Acne
Problem Substances : Insulin
[+]

Associations between celiac disease and type 1 diabetes: 4.4-11.1% of type 1 diabetes patients also have co-existing celiac disease as compared to 0.5% of the general population. The effects of a gluten-free diet are discussed.Mar 25, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ital J Pediatr. 2012 Mar 26 ;38(1):10. Epub 2012 Mar 26. PMID: 22449104
Article Published Date : Mar 25, 2012
Study Type : Review
Additional Links
Diseases : Celiac Disease, Diabetes Mellitus: Type 1
Therapeutic Actions : Dietary Modification: Wheat/Gluten Free
Additional Keywords : Genotype, Glycemic Index, HLA-DQ2/DQ8
Problem Substances : Gluten, Insulin
[+]

Insulin induces the expression of delta-5 desaturase (FADS1) in a dose-dependent manner which may explain insulin's regulation of dihomo-gamma-linoleic acid to inflammatory arachidonic acid.Jul 01, 2011

Pubmed Data : Scand J Clin Lab Invest. 2011 Jul ;71(4):330-9. Epub 2011 Mar 17. PMID: 21413848
Article Published Date : Jul 01, 2011
Study Type : In Vitro Study
Additional Links
Additional Keywords : arachidonic acid, Dose Response, High Sugar Diet, hyperinsulinemia, Inflammation, Insulin Resistance
Problem Substances : Insulin
Adverse Pharmacological Actions : Endocrine Disruptor: Insulin Resistance, Inflammatory
[+]

Oleuropein inhibits the cytotoxicity induced by amylin amyloids, a hallmark feature of type 2 diabetes.Sep 25, 2017

Pubmed Data : Biochemistry. 2017 Sep 26 ;56(38):5035-5039. Epub 2017 Sep 13. PMID: 28829122
Article Published Date : Sep 25, 2017
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids, Oleuropein
Diseases : Amyloidosis, Diabetes Mellitus: Type 2
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Insulin
[+]

Olive leaf extract protects against cytokine-induced β-cell damage through maintenance of redox homeostasis.Jun 01, 2011

Pubmed Data : Rejuvenation Res. 2011 Jun ;14(3):325-34. Epub 2011 Jul 11. PMID: 21745095
Article Published Date : Jun 01, 2011
Study Type : Plant Study
Additional Links
Substances : Oleuropein, Polyphenols
Pharmacological Actions : Apoptotic, Superoxide Dismutase Up-regulation
Additional Keywords : Cytotoxicity, Olive Leaf Extract, Plant Extracts
Problem Substances : Insulin
[+]

Puerarin may be effective in preventing islet cells from the toxic action of reactive oxygen species in diabetes.Jan 03, 2006

Pubmed Data : Eur J Pharmacol. 2006 Jan 4 ;529(1-3):1-7. PMID: 16321378
Article Published Date : Jan 03, 2006
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Hydrogen Peroxide Induced Toxicity
Pharmacological Actions : Anti-Apoptotic, Pancreato Protective Agents, Superoxide Dismutase Up-regulation
Problem Substances : Insulin
[+]

The folding pattern (conformation) of insulin analogues may contribute profoundly to their differences in toxicity and efficacy.Nov 17, 2014

Pubmed Data : Diabetes Metab. 2014 Nov 18 ;40(6):483-484. Epub 2014 Nov 18. PMID: 25459321
Article Published Date : Nov 17, 2014
Study Type : Commentary
Additional Links
Additional Keywords : Conformational State, Insulin Degludec, Insulin Glargine
Problem Substances : Insulin (Synthetically Produced)

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