Insulin

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53 Diseases Researched for Insulin
NameACCKFocus
Insulin Resistance22135Locked
Diabetes Mellitus: Type 21695Locked
Obesity1149Locked
Adiponectin: Low Levels746Locked
Hyperglycemia542Locked
Hyperinsulinism737Locked
Diabetes Mellitus: Type 1: Prevention636Locked
Oxidative Stress832Locked
Cardiovascular Diseases330Locked
Inflammation623Locked
Hyperlipidemia322Locked
Cancers: All321Locked
Celiac Disease321Locked
High Cholesterol220Locked
Kidney Cancer120Locked
Liver Cancer120Locked
Lung Cancer120Locked
Pancreatic Cancer120Locked
Respiratory Cancers120Locked
Stomach Cancer120Locked
Fatty Liver518Locked
Diabetes Mellitus: Type 1413Locked
All-Cause Mortality110Locked
Breastfeeding Concerns: Chemical Exposure110Locked
Diabetes: Cancer Risk110Locked
Diabetes: Cardiovascular Illness110Locked
Endothelial Dysfunction110Locked
Heart Disease: Ischemic110Locked
Metabolic Diseases110Locked
Myocardial Ischemia110Locked
Nonalcoholic fatty liver disease (NAFLD)110Locked
Polycystic Ovary Syndrome110Locked
Prediabetes110Locked
Statin-Induced Pathologies110Locked
Lipopolysaccharide-Induced Toxicity15Locked
Radiation Induced Illness15Locked
Hypertension24Locked
Lipid Peroxidation24Locked
Triglycerides: Elevated24Locked
Acne22Locked
Aging: Brain 12Locked
Alcohol Toxicity 12Locked
Atherosclerosis12Locked
Diabetic Complications12Locked
Fructose-Induced Toxicity 12Locked
High Fat Diet12Locked
Liver Damage12Locked
Liver Stress: Fructose-Induced12Locked
Myopia12Locked
Weight Problems12Locked
Amyloidosis11Locked
Hydrogen Peroxide Induced Toxicity11Locked
Insulin: Elevated11Locked
9 Adverse Pharmacological Actions Researched for Insulin
NameACCKFocus
Carcinogenic120Locked
Endocrine Disruptor: Insulin Resistance211Locked
Carcinogenic (suspected)110Locked
Inflammatory23Locked
Dyslipidemic12Locked
Gluconeogenesis Up-Regulation12Locked
Lipogenesis Up-Regulation12Locked
Myopiagenic 12Locked
Insulinotropic11Locked
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View the Evidence:
70 Abstracts with Insulin Research

[+]

Meta-analysis: The use of insulin and insulin analogs increase the risk of various cancers.Oct 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Curr Drug Saf. 2013 Nov ;8(5):333-48. PMID: 24215311
Article Published Date : Oct 31, 2013
Study Type : Meta Analysis
Additional Links
Diseases : Kidney Cancer, Liver Cancer, Lung Cancer, Pancreatic Cancer, Respiratory Cancers, Stomach Cancer
Problem Substances : Insulin
Adverse Pharmacological Actions : Carcinogenic
[+]

"A Palaeolithic diet improves glucose tolerance more than a Mediterranean-like diet in individuals with ischaemic heart disease."Sep 01, 2007

Pubmed Data : Diabetologia. 2007 Sep ;50(9):1795-807. Epub 2007 Jun 22. PMID: 17583796
Article Published Date : Sep 01, 2007
Study Type : Human Study
Additional Links
Diseases : Diabetes Mellitus: Type 2, Heart Disease: Ischemic, Myocardial Ischemia
Therapeutic Actions : Dietary Modification: Paleolithic/Stone Age Diet
Problem Substances : Insulin
[+]

A glutenfree diet showed short-term benefits by reducing GI symptoms and severe hypoglycaemia in T1D and CDMay 31, 2011

Pubmed Data : Pediatr Diabetes. 2011 Jun ;12(4 Pt 1):322-5. Epub 2011 Mar 29. PMID: 21615651
Article Published Date : May 31, 2011
Study Type : Human Study
Additional Links
Diseases : Celiac Disease, Diabetes Mellitus: Type 1: Prevention
Additional Keywords : Autoantibodies, Body Mass Index (BMI), Glycosylated Haemoglobin (HbA1c), Hypoglycemia
Problem Substances : Gluten, Insulin
[+]

A nutraceutical formula containing berberine, chlorogenic acid, and tocotrienols was found to improve a large number of metabolic and liver parameters in overweight subjects.Mar 28, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr J. 2015 Mar 28 ;14:30. Epub 2015 Mar 28. PMID: 25886384
Article Published Date : Mar 28, 2015
Study Type : Human Study
Additional Links
Substances : Berberine, Chlorogenic Acid, Tocotrienols
Diseases : Fatty Liver, Hyperlipidemia, Insulin Resistance
Problem Substances : Insulin
[+]

Acute epigallocatechin-3-gallate supplementation delays gastric emptying in healthy women.Aug 20, 2018

Pubmed Data : Nutrients. 2018 Aug 20 ;10(8). Epub 2018 Aug 20. PMID: 30127247
Article Published Date : Aug 20, 2018
Study Type : Human Study
Additional Links
Substances : Catechin
Diseases : Adiponectin: Low Levels
Pharmacological Actions : Adiponectin upregulation
Problem Substances : Insulin
[+]

Atorvastatin causes insulin resistance and increases ambient glycemia in hypercholesterolemic patientsMar 23, 2010

Pubmed Data : J Am Coll Cardiol. 2010 Mar 23 ;55(12):1209-16. PMID: 20298928
Article Published Date : Mar 23, 2010
Study Type : Human Study
Additional Links
Diseases : High Cholesterol, Hyperglycemia, Insulin Resistance, Statin-Induced Pathologies
Problem Substances : Atorvastatin, Insulin , Statin Drugs
Adverse Pharmacological Actions : Endocrine Disruptor: Insulin Resistance
[+]

Current guides for medical treatment suggest that insulin does not pass into milk, which is untrue.Jan 01, 2012

Pubmed Data : Int J Endocrinol. 2012 ;2012:296368. Epub 2012 Mar 5. PMID: 22500167
Article Published Date : Jan 01, 2012
Study Type : Human Study
Additional Links
Diseases : Breastfeeding Concerns: Chemical Exposure
Problem Substances : Insulin
[+]

Daily consumption of one egg may reduce the risk of diabetes without any adverse effects on lipid profiles in individuals with pre- and type II diabetes.Aug 14, 2018

Pubmed Data : Food Funct. 2018 Aug 15 ;9(8):4469-4479. PMID: 30073224
Article Published Date : Aug 14, 2018
Study Type : Human Study
Additional Links
Substances : Egg
Diseases : Diabetes Mellitus: Type 2, Insulin Resistance, Prediabetes
Pharmacological Actions : Hypoglycemic Agents
Additional Keywords : Risk Reduction
Problem Substances : Insulin
[+]

Flaxseed fiber suppresses postprandial lipemia and appetite in healthy young men.Feb 01, 2013

Pubmed Data : Nutr Metab Cardiovasc Dis. 2013 Feb ;23(2):136-43. Epub 2011 Jul 29. PMID: 21802266
Article Published Date : Feb 01, 2013
Study Type : Human Study
Additional Links
Substances : Fiber, Flaxseed
Diseases : Hyperlipidemia
Pharmacological Actions : Antilipemic Agents, Appetite Suppresant
Problem Substances : Insulin
[+]

Four grams of high molecular weight oat β-glucan lowers appetite but not ad libitum eating and beneficially modulates postprandial glycemia.Jan 01, 2018

Pubmed Data : Appetite. 2018 09 1 ;128:197-204. Epub 2018 Jun 18. PMID: 29920323
Article Published Date : Jan 01, 2018
Study Type : Human Study
Additional Links
Substances : Beta-glucan
Diseases : Hyperglycemia, Hyperinsulinism
Pharmacological Actions : Hypoglycemic Agents
Problem Substances : Insulin
[+]

Girls with PCOS and IR more hirsute, more AN, lower SHBG and higher fasting insulin levelsMay 31, 2010

Pubmed Data : J Pediatr Adolesc Gynecol. 2010 Jun ;23(3):158-61. Epub 2009 Dec 5. PMID: 19963413
Article Published Date : May 31, 2010
Study Type : Human Study
Additional Links
Diseases : Insulin Resistance, Polycystic Ovary Syndrome
Problem Substances : Insulin
[+]

Green tea extract decreased fasting insulin concentrations in those with elevated baseline fasting concentrations.Jan 01, 2016

Pubmed Data : J Nutr. 2016 Jan ;146(1):38-45. Epub 2015 Nov 18. PMID: 26581683
Article Published Date : Jan 01, 2016
Study Type : Human Study
Additional Links
Substances : Catechin , Polyphenols, Tea
Diseases : Adiponectin: Low Levels, Obesity
Therapeutic Actions : Fasting/Caloric Restriction
Additional Keywords : Plant Extracts
Problem Substances : Insulin
[+]

Higher egg intake was associated with a lower risk of T2D in this cohort of middle-aged and older men.Apr 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Clin Nutr. 2015 May ;101(5):1088-96. Epub 2015 Apr 1. PMID: 25832339
Article Published Date : Apr 30, 2015
Study Type : Human Study
Additional Links
Substances : Egg
Diseases : Diabetes Mellitus: Type 2
Additional Keywords : Risk Reduction
Problem Substances : Insulin
[+]

Hypocaloric, plant-based short-term dietary oatmeal interventions significantly reduced mean blood glucose levels and mean required daily insulin doses in a critically ill and septic patient in the intensive care unit.Oct 01, 2019

Pubmed Data : Complement Ther Med. 2019 Oct ;46:69-72. Epub 2019 Jul 30. PMID: 31519290
Article Published Date : Oct 01, 2019
Study Type : Human Study
Additional Links
Substances : Oats
Diseases : Insulin Resistance
Pharmacological Actions : Insulin Sensitizers
Problem Substances : Insulin
[+]

In this uncontrolled pilot study, hospital admission and diabetes adapted diet followed by oatmeal intervention achieved a approximately 40% reduction of insulin dosage required to achieve controlled glucose levels.Feb 01, 2008

Pubmed Data : Exp Clin Endocrinol Diabetes. 2008 Feb ;116(2):132-4. Epub 2007 Dec 20. PMID: 18095234
Article Published Date : Feb 01, 2008
Study Type : Human Study
Additional Links
Diseases : Adiponectin: Low Levels, Diabetes Mellitus: Type 2, Insulin Resistance
Pharmacological Actions : Insulin Sensitizers
Problem Substances : Insulin
[+]

Including indigestible carbohydrates in the evening meal of healthy subjects improves glucose tolerance, lowers inflammatory markers, and increases satiety after a subsequent standardized breakfast.Apr 01, 2008

Pubmed Data : J Nutr. 2008 Apr ;138(4):732-9. PMID: 18356328
Article Published Date : Apr 01, 2008
Study Type : Human Study
Additional Links
Substances : Fiber
Diseases : Adiponectin: Low Levels, Inflammation, Insulin Resistance
Pharmacological Actions : Adiponectin upregulation, Interleukin-6 Downregulation
Problem Substances : Insulin
[+]

Increasing nutritional fiber results in reduced serum ZO levels, reduced liver enzymes and improved hepatic steatosis in patients with NAFLDNov 17, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2018 Nov 18 ;10(11). Epub 2018 Nov 18. PMID: 30453660
Article Published Date : Nov 17, 2018
Study Type : Human Study
Additional Links
Substances : Fiber
Diseases : Insulin Resistance, Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Gastroprotective
Problem Substances : Insulin
[+]

Insulin use is associated with increased pancreatic cancer risk in the short-term in diabetics.Jul 22, 2014

Pubmed Data : Ann Oncol. 2014 Jul 23. Epub 2014 Jul 23. PMID: 25057164
Article Published Date : Jul 22, 2014
Study Type : Human Study
Additional Links
Diseases : Diabetes: Cancer Risk
Problem Substances : Insulin
Adverse Pharmacological Actions : Carcinogenic (suspected)
[+]

Insulin-free whey-based cow's milk formula is associated with lower incidence of beta cell autoimmunity in infants and young children.. Mar 05, 2012

Pubmed Data : Arch Pediatr Adolesc Med. 2012 Mar 5. Epub 2012 Mar 5. PMID: 22393174
Article Published Date : Mar 05, 2012
Study Type : Human Study
Additional Links
Diseases : Diabetes Mellitus: Type 1
Problem Substances : Cow Milk, Insulin
[+]

Oatmeal diet days may improve insulin resistance in patients with type 2 diabetes mellitus.Jan 01, 2013

Pubmed Data : Forsch Komplementmed. 2013 ;20(6):465-8. Epub 2013 Dec 13. PMID: 24434762
Article Published Date : Jan 01, 2013
Study Type : Human Study
Additional Links
Substances : Oats
Diseases : Diabetes Mellitus: Type 2, Insulin Resistance, Obesity
Problem Substances : Insulin
[+]

Orange pomace fiber lowers postprandial glycemic and insulinemic responses in men with increased cardiometabolic risk.Jan 01, 2016

Pubmed Data : J Nutr. 2016 06 ;146(6):1197-203. Epub 2016 May 11. PMID: 27170728
Article Published Date : Jan 01, 2016
Study Type : Human Study
Additional Links
Substances : Fiber
Diseases : Cardiovascular Diseases, Hyperglycemia, Hyperinsulinism
Pharmacological Actions : Hypoglycemic Agents
Problem Substances : Insulin
[+]

Patients with type 2 diabetes who use sulfonylureas or insulin have an increased risk for cancer-related mortality. Feb 01, 2006

Pubmed Data : Diabetes Care. 2006 Feb;29(2):254-8. PMID: 16443869
Article Published Date : Feb 01, 2006
Study Type : Human Study
Additional Links
Diseases : Cancers: All, Diabetes Mellitus: Type 2
Additional Keywords : Drug: Metformin
Problem Substances : Glipizide, Glyburide, Insulin , Metformin , Sulfonylureas
[+]

Postmeal fluctuations in blood glucose and insulin induced by sucrose are alleviated when sucrose is consumed with blackcurrants or lingonberries. Aug 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Clin Nutr. 2012 Sep ;96(3):527-33. Epub 2012 Aug 1. PMID: 22854401
Article Published Date : Aug 31, 2012
Study Type : Human Study
Additional Links
Substances : Black Currant, Lingonberry
Diseases : Hyperinsulinism
Pharmacological Actions : Glucose Uptake Optimization
Additional Keywords : Metabolic Regulation
Problem Substances : Insulin , Sucrose
[+]

Resveratrol improves insulin resistance, glucose and lipid metabolism in patients with non-alcoholic fatty liver disease.Mar 01, 2015

Pubmed Data : Dig Liver Dis. 2015 Mar ;47(3):226-32. Epub 2014 Dec 16. PMID: 25577300
Article Published Date : Mar 01, 2015
Study Type : Human Study
Additional Links
Substances : Resveratrol, Stilbenes
Diseases : Insulin Resistance
Pharmacological Actions : Adiponectin upregulation, Anti-Inflammatory Agents, Anticholesteremic Agents, Hypoglycemic Agents, Insulin Sensitizers
Problem Substances : Insulin
[+]

Supplementation of a gamma-tocopherol-rich mixture of tocopherols in healthy men protects against vascular endothelial dysfunction.Dec 31, 2012

Pubmed Data : J Nutr Biochem. 2013 Jan ;24(1):196-203. Epub 2012 Jul 25. PMID: 22841396
Article Published Date : Dec 31, 2012
Study Type : Human Study
Additional Links
Substances : Arginine, Vitamin C, Vitamin E, Vitamin E: Gamma-Tocopherol
Diseases : Endothelial Dysfunction, Hyperglycemia, Oxidative Stress
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation
Problem Substances : Insulin
[+]

T-cell response to insulin peptide A1-12 enhanced in clinical and preclinical T1D associated with high-risk HLA-genotypeAug 31, 2008

Pubmed Data : J Autoimmun. 2008 Sep ;31(2):142-8. Epub 2008 Jun 18. PMID: 18565729
Article Published Date : Aug 31, 2008
Study Type : Human Study
Additional Links
Diseases : Diabetes Mellitus: Type 1: Prevention
Additional Keywords : HLA Genotypes
Problem Substances : Insulin
[+]

The addition of beta glucan to a meal slows the appearance of glucose in plasma, resulting in longer-lasting insulin secretion which exerts a prolonged inhibition of endogenous glucose production and lipolysis.Mar 01, 2009

Pubmed Data : Mol Nutr Food Res. 2009 Mar ;53(3):361-9. PMID: 18837470
Article Published Date : Mar 01, 2009
Study Type : Human Study
Additional Links
Substances : Beta-glucan, Fiber
Pharmacological Actions : Insulin Sensitizers
Problem Substances : Insulin
[+]

There may be an association between increasing exogenous insulin dose and increased risk of all-cause mortality.Mar 31, 2015

Pubmed Data : Diabetes Obes Metab. 2015 Apr ;17(4):350-62. Epub 2014 Dec 10. PMID: 25399739
Article Published Date : Mar 31, 2015
Study Type : Human Study
Additional Links
Diseases : All-Cause Mortality, Cancers: All, Cardiovascular Diseases, Diabetes: Cardiovascular Illness, Diabetes Mellitus: Type 2
Additional Keywords : Increased Risk
Problem Substances : Insulin
[+]

This study found that that taking green tea, capsaicin and ginger co-supplements for 8 weeks among overweight women had beneficial effects on weight, BMI, markers of insulin metabolism and plasma glutathione levels.Jan 01, 2017

Pubmed Data : Ann Nutr Metab. 2017 ;70(4):277-285. Epub 2017 Jun 9. PMID: 28595182
Article Published Date : Jan 01, 2017
Study Type : Human Study
Additional Links
Substances : Capsaicin, Ginger, Green Tea, Tea
Diseases : Insulin Resistance, Obesity, Oxidative Stress
Pharmacological Actions : Antioxidant Effects, Insulin Sensitizers
Additional Keywords : Plant Extracts
Problem Substances : Insulin
[+]

Whole grains reduce postprandial insulin and triglyceride responses.Aug 01, 2014

Pubmed Data : Nutr Metab Cardiovasc Dis. 2014 Aug ;24(8):837-44. Epub 2014 Jan 28. PMID: 24598599
Article Published Date : Aug 01, 2014
Study Type : Human Study
Additional Links
Diseases : Cardiovascular Diseases, Diabetes Mellitus: Type 2, Metabolic Diseases
Problem Substances : Insulin
[+]

Extremely low frequency electromagnetic fields downregulate insulin secretion.Jun 24, 2005

Pubmed Data : Biochem Biophys Res Commun. 2005 Jun 24 ;332(1):28-32. PMID: 15896294
Article Published Date : Jun 24, 2005
Study Type : Human In Vitro
Additional Links
Diseases : Radiation Induced Illness
Anti Therapeutic Actions : Electromagnetic Field Harms, Electromagnetic Radiation
Problem Substances : Insulin
[+]

Resveratrol could be a prime candidate in ameliorating dysfunctioning adipose tissue induced by inflammatory stimulation.Jan 01, 2016

Pubmed Data : PLoS One. 2016 ;11(7):e0159747. Epub 2016 Jul 20. PMID: 27438462
Article Published Date : Jan 01, 2016
Study Type : Human In Vitro
Additional Links
Substances : Resveratrol, Stilbenes
Diseases : Inflammation, Insulin Resistance, Lipopolysaccharide-Induced Toxicity, Obesity
Pharmacological Actions : Anti-Inflammatory Agents
Problem Substances : Insulin
[+]

"Brain insulin impairs amyloid-beta(1-40) clearance from the brain."Oct 26, 2004

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Neurosci. 2004 Oct 27 ;24(43):9632-7. PMID: 15509750
Article Published Date : Oct 26, 2004
Study Type : Animal Study
Additional Links
Diseases : Aging: Brain , Hyperinsulinism
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Insulin
[+]

"Hypothalamic orexin stimulates feeding-associated glucose utilization in skeletal muscle via sympathetic nervous system."Nov 30, 2009

Pubmed Data : Cell Metab. 2009 Dec ;10(6):466-80. PMID: 19945404
Article Published Date : Nov 30, 2009
Study Type : Animal Study
Additional Links
Problem Substances : Insulin
[+]

A high fructose diet may contribute to the development of fatty liver, gluconeogenesis up-regulation and inflammation. May 01, 2010

Pubmed Data : Endocrinology. 2010 May;151(5):2040-9. Epub 2010 Mar 8. PMID: 20211973
Article Published Date : May 01, 2010
Study Type : Animal Study
Additional Links
Diseases : Fatty Liver, Fructose-Induced Toxicity , Hyperglycemia, Inflammation, Liver Stress: Fructose-Induced, Triglycerides: Elevated
Problem Substances : Insulin
Adverse Pharmacological Actions : Dyslipidemic, Gluconeogenesis Up-Regulation, Inflammatory, Lipogenesis Up-Regulation
[+]

An aqueous extract of white tea is effective to reduce most of the diabetes associated abnormalities in a steptozotocin-induced diabetes model of rats.Dec 14, 2011

Pubmed Data : Phytomedicine. 2011 Dec 15 ;19(1):25-31. Epub 2011 Jul 30. PMID: 21802923
Article Published Date : Dec 14, 2011
Study Type : Animal Study
Additional Links
Substances : White Tea
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Anticholesteremic Agents, Antioxidants, Hypoglycemic Agents
Additional Keywords : Phytotherapy, Plant Extracts
Problem Substances : Insulin
[+]

Anti-diabetic activity of Zingiber officinale in streptozotocin-induced type I diabetic rats.Dec 31, 2003

Pubmed Data : J Pharm Pharmacol. 2004 Jan ;56(1):101-5. PMID: 14980006
Article Published Date : Dec 31, 2003
Study Type : Animal Study
Additional Links
Substances : Ginger
Diseases : Diabetes Mellitus: Type 1: Prevention, Hypertension
Pharmacological Actions : Hypoglycemic Agents, Insulin-releasing
Additional Keywords : Phytotherapy
Problem Substances : Insulin
[+]

Beta-glucan and mulberry have synergistic effects on metabolic disorders.Oct 12, 2017

Pubmed Data : Nutrients. 2017 Oct 12 ;9(10). Epub 2017 Oct 12. PMID: 29023387
Article Published Date : Oct 12, 2017
Study Type : Animal Study
Additional Links
Substances : Beta-glucan, Mulberry
Diseases : Insulin Resistance, Obesity, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hypoglycemic Agents
Additional Keywords : Drug Synergy, Plant Extracts
Problem Substances : Insulin
[+]

Blueberry and mulberry juice prevent obesity development in C57BL/6 mice.Dec 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2013 ;8(10):e77585. Epub 2013 Oct 15. PMID: 24143244
Article Published Date : Dec 31, 2012
Study Type : Animal Study
Additional Links
Substances : Blueberry, Mulberry
Diseases : Obesity
Pharmacological Actions : Anticholesteremic Agents
Additional Keywords : Anti-Obesity Agents
Problem Substances : Insulin
[+]

Camel milk inhibits the diabetes-induced elevation in incretin hormones, TNF-α and TGF-β1 levels.May 31, 2014

Pubmed Data : Horm Metab Res. 2014 Jun ;46(6):404-11. Epub 2014 Mar 13. PMID: 24627103
Article Published Date : May 31, 2014
Study Type : Animal Study
Additional Links
Substances : Camel Milk
Diseases : Atherosclerosis, Diabetes Mellitus: Type 2, Insulin Resistance
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Anti-Inflammatory Agents, Hypoglycemic Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Insulin
[+]

Dietary catechins lower blood glucose levels, mitigate oxidative stress, and inhibit the angiotension-converting enzyme.Dec 01, 2007

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 2007 Dec ;53(6):496-500. PMID: 18202537
Article Published Date : Dec 01, 2007
Study Type : Animal Study
Additional Links
Substances : Catechin , Tea
Diseases : Hypertension, Oxidative Stress
Pharmacological Actions : Antihypertensive Agents, Antioxidant Effects, Hypoglycemic Agents
Problem Substances : Insulin
[+]

Flower and inflorescence stalk of M. balbisiana Colla. possess significant antidiabetic, antihyperlipidemic, and antioxidant activities.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Indian J Pharmacol. 2017 Jan-Feb;49(1):71-76. PMID: 28458426
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Banana
Diseases : Diabetes Mellitus: Type 1: Prevention
Pharmacological Actions : Antioxidants, Hypoglycemic Agents
Additional Keywords : Plant Extracts
Problem Substances : Insulin
[+]

Grape seed extract prevents adverse metabolic alterations through tis anti-inflammatory and antioxidant action.Oct 01, 2017

Pubmed Data : Phytother Res. 2017 Oct ;31(10):1621-1632. Epub 2017 Aug 25. PMID: 28840618
Article Published Date : Oct 01, 2017
Study Type : Animal Study
Additional Links
Substances : Anthocyanins, Polyphenols
Diseases : Adiponectin: Low Levels, Inflammation, Insulin Resistance, Obesity, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
Problem Substances : Insulin
[+]

Insulin may contribute to myopia. Jan 01, 2009

Pubmed Data : Invest Ophthalmol Vis Sci. 2009 Jan;50(1):13-23. Epub 2008 Jul 3. PMID: 18599564
Article Published Date : Jan 01, 2009
Study Type : Animal Study
Additional Links
Diseases : Hyperinsulinism, Myopia
Additional Keywords : Diseases that are Linked
Problem Substances : Insulin
Adverse Pharmacological Actions : Myopiagenic
[+]

Mate tea reduces high fat diet-induced liver and metabolic disorders in mice.Jan 01, 2019

Pubmed Data : Biomed Pharmacother. 2019 Jan ;109:1547-1555. Epub 2018 Nov 14. PMID: 30551407
Article Published Date : Jan 01, 2019
Study Type : Animal Study
Additional Links
Substances : Tea
Diseases : Fatty Liver, Inflammation, Insulin Resistance, Lipid Peroxidation, Obesity, Oxidative Stress
Additional Keywords : Plant Extracts
Problem Substances : Insulin
[+]

Meal-anticipatory glucagon-like peptide-1 secretion in rats.Jan 31, 2010

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Endocrinology. 2010 Feb ;151(2):569-75. Epub 2009 Nov 13. PMID: 19915164
Article Published Date : Jan 31, 2010
Study Type : Animal Study
Additional Links
Pharmacological Actions : Glucagon Like peptide 1 (GLP-1) Up-regulation
Additional Keywords : Food-anticipatory
Problem Substances : Insulin
[+]

Monosodium glutamate induces fatty liver, insulin and triglyceride elevations, increased weight gain and adverse liver changes.Aug 01, 2009

Pubmed Data : J Lipid Res. 2009 Aug;50(8):1521-37. Epub 2008 Nov 11. PMID: 19001666
Article Published Date : Aug 01, 2009
Study Type : Animal Study
Additional Links
Diseases : Fatty Liver, Hyperinsulinism, Liver Damage, Triglycerides: Elevated, Weight Problems
Problem Substances : Insulin , Monosodium Glutamate (MSG), Trans Fatty Acids
[+]

Nigella sativa exerts lipid-lowering and insulin-sensitizing actions in the rat.Sep 30, 2004

Pubmed Data : J Ethnopharmacol. 2004 Oct ;94(2-3):251-9. PMID: 15325727
Article Published Date : Sep 30, 2004
Study Type : Animal Study
Additional Links
Substances : Nigella sativa (aka Black Seed)
Diseases : Hyperlipidemia, Insulin Resistance
Pharmacological Actions : Hypolipidemic, Insulin Sensitizers
Additional Keywords : Plant Extracts
Problem Substances : Insulin
[+]

P. alata has anti-inflammatory properties, contributing to the protection of beta cells in pancreatic islets in NOD mice.May 31, 2016

Pubmed Data : Int Immunopharmacol. 2016 Jun ;35:127-136. Epub 2016 Apr 16. PMID: 27039211
Article Published Date : May 31, 2016
Study Type : Animal Study
Additional Links
Substances : Passion Flower
Diseases : Diabetes Mellitus: Type 1: Prevention, Lipid Peroxidation
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Pancreato Protective Agents
Additional Keywords : Plant Extracts
Problem Substances : Insulin
[+]

Phloretin might be able to increase insulin sensitivity and alleviate the metabolic diseases.Nov 30, 2014

Pubmed Data : J Nutr Biochem. 2014 Dec ;25(12):1296-308. Epub 2014 Sep 16. PMID: 25283330
Article Published Date : Nov 30, 2014
Study Type : Animal Study
Additional Links
Substances : Phloretin
Diseases : Insulin Resistance
Pharmacological Actions : Insulin Sensitizers
Problem Substances : Insulin
[+]

Puerarin alleviates insulin resistance and improves glucolipid metabolism in T2DM.Jun 19, 2021

Pubmed Data : Nan Fang Yi Ke Da Xue Xue Bao. 2021 Jun 20 ;41(6):839-846. PMID: 34238735
Article Published Date : Jun 19, 2021
Study Type : Animal Study
Additional Links
Diseases : Diabetes Mellitus: Type 2, Insulin Resistance
Pharmacological Actions : Hypoglycemic Agents
Problem Substances : Insulin
[+]

Purified betacyanins from Hylocereus undatus peel ameliorate obesity and insulin resistance in high-fat-diet-fed mice.Jan 12, 2016

Pubmed Data : J Agric Food Chem. 2016 Jan 13 ;64(1):236-44. Epub 2015 Dec 24. PMID: 26653843
Article Published Date : Jan 12, 2016
Study Type : Animal Study
Additional Links
Substances : Dragon Fruit
Diseases : High Fat Diet, Insulin Resistance, Obesity
Additional Keywords : Anti-Obesity Agents, Gene Expression Regulation, Plant Extracts
Problem Substances : Insulin
[+]

Quercetin could potentially be used to ameliorate myocardial damage due to oxidative stress, inflammation and apoptosis in diabetes.Jan 31, 2017

Pubmed Data : Biomed Pharmacother. 2017 Feb ;86:570-582. Epub 2016 Dec 24. PMID: 28027533
Article Published Date : Jan 31, 2017
Study Type : Animal Study
Additional Links
Substances : Quercetin
Diseases : Diabetic Complications, Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Cardioprotective
Problem Substances : Insulin
[+]

Rats may have a diabetic-like response to magnetic fields.Dec 01, 1991

Pubmed Data : Invest Radiol. 1991 Dec ;26(12):1095-100. PMID: 1765445
Article Published Date : Dec 01, 1991
Study Type : Animal Study
Additional Links
Diseases : Diabetes Mellitus: Type 2
Anti Therapeutic Actions : Electromagnetic Field Harms, Electromagnetic Radiation
Problem Substances : Insulin
[+]

Rats may have a diabetic-like response to magnetic fields.Dec 01, 1991

Pubmed Data : Invest Radiol. 1991 Dec ;26(12):1095-100. PMID: 1765445
Article Published Date : Dec 01, 1991
Study Type : Animal Study
Additional Links
Diseases : Diabetes Mellitus: Type 2
Anti Therapeutic Actions : Electromagnetic Field Harms, Electromagnetic Radiation
Problem Substances : Insulin
[+]

Resveratrol alleviates ethanol-induced hormonal and metabolic disturbances in the rat.Jan 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Physiol Res. 2017 03 31 ;66(1):135-145. Epub 2016 Oct 26. PMID: 27782737
Article Published Date : Jan 31, 2017
Study Type : Animal Study
Additional Links
Substances : Resveratrol, Stilbenes
Diseases : Adiponectin: Low Levels, Alcohol Toxicity
Problem Substances : Insulin
[+]

Starch and β-glucan in a whole grain-like structural form have the potential as a dietary strategy to combat obesity-induced hepatic insulin resistance for improved health.Aug 01, 2019

Pubmed Data : Food Funct. 2019 Aug 1 ;10(8):5091-5101. Epub 2019 Jul 31. PMID: 31363728
Article Published Date : Aug 01, 2019
Study Type : Animal Study
Additional Links
Substances : Beta-glucan
Diseases : Insulin Resistance, Obesity
Pharmacological Actions : Inhibitor of Nuclear Factor Kappa-B Kinase (IKK), Insulin Sensitizers, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Insulin
[+]

Sulforaphane is a promising agent to restore glucose tolerance through upregulation of insulin signaling in obese mice.Sep 19, 2018

Pubmed Data : Food Funct. 2018 Sep 19 ;9(9):4695-4701. PMID: 30091431
Article Published Date : Sep 19, 2018
Study Type : Animal Study
Additional Links
Substances : Sulforaphane
Diseases : Insulin Resistance
Pharmacological Actions : Glucose Uptake Optimization, Insulin Sensitizers
Additional Keywords : Broccoli, Broccoli Sprouts, Cruciferous Vegetables, Isothiocyanates
Problem Substances : Insulin
[+]

These results show that chronic consumption of β-glucans can improve glucose control and decrease fatty liver in a model of diabetes with obesity.Oct 01, 2013

Pubmed Data : Eur J Nutr. 2013 Oct ;52(7):1743-53. Epub 2012 Dec 11. PMID: 23229409
Article Published Date : Oct 01, 2013
Study Type : Animal Study
Additional Links
Substances : Beta-glucan, Fiber
Diseases : Adiponectin: Low Levels, Diabetes Mellitus: Type 2, Fatty Liver, Insulin Resistance, Obesity
Pharmacological Actions : Adiponectin upregulation, Antioxidant
Problem Substances : Insulin
[+]

Tocotrienol-rich fraction supplementation reduces hyperglycemia-induced skeletal muscle damage through regulation of insulin signaling and oxidative stress in type 2 diabetic mice.Jan 01, 2018

Pubmed Data : J Nutr Biochem. 2018 07 ;57:77-85. Epub 2018 Mar 21. PMID: 29679925
Article Published Date : Jan 01, 2018
Study Type : Animal Study
Additional Links
Substances : Tocotrienols
Diseases : Diabetes Mellitus: Type 2, Oxidative Stress
Pharmacological Actions : Antioxidant, Insulin Sensitizers
Problem Substances : Insulin
[+]

Treatment with C. comosa and its diarylheptanoid derivative improved glucose and lipid metabolism in estrogen-deprived rats.Mar 29, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2012 Mar 30 ;12:28. Epub 2012 Mar 30. PMID: 22463706
Article Published Date : Mar 29, 2012
Study Type : Animal Study
Additional Links
Substances : Curcuma Comosa
Diseases : Dyslipidemias, Insulin Resistance
Pharmacological Actions : Hypoglycemic Agents, Hypolipidemic
Additional Keywords : Ovariectomy-Induced Changes, Plant Extracts
Problem Substances : Insulin
[+]

Treatments with lotus seedpod oligomeric procyanidins could be beneficial in diabetic treatments.May 16, 2017

Pubmed Data : J Agric Food Chem. 2017 May 17 ;65(19):3801-3810. Epub 2017 May 8. PMID: 28314100
Article Published Date : May 16, 2017
Study Type : Animal Study
Additional Links
Substances : Lotus
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Hypoglycemic Agents, Hypolipidemic
Additional Keywords : Plant Extracts, Proanthocyanidins
Problem Substances : Insulin
[+]

"Over-stimulation of insulin/IGF-1 signaling by western diet may promote diseases of civilization."Jan 01, 2011

Pubmed Data : Nutr Metab (Lond). 2011 ;8:41. Epub 2011 Jun 24. PMID: 21699736
Article Published Date : Jan 01, 2011
Study Type : Review
Additional Links
Diseases : Acne, Cancers: All, Diabetes Mellitus: Type 1, Hyperinsulinism, Insulin: Elevated
Anti Therapeutic Actions : Western Diet
Problem Substances : Cow Milk, Insulin
Adverse Pharmacological Actions : Insulinotropic
[+]

Acne development and androgen level changes due to high glycemic loads affecting serum insulin and insulin-like growth factor-1 levels.Oct 31, 2010

Pubmed Data : Clin Dermatol. 2010 Nov-Dec;28(6):598-604. PMID: 21034984
Article Published Date : Oct 31, 2010
Study Type : Review
Additional Links
Diseases : Acne
Problem Substances : Insulin
[+]

Associations between celiac disease and type 1 diabetes: 4.4-11.1% of type 1 diabetes patients also have co-existing celiac disease as compared to 0.5% of the general population. The effects of a gluten-free diet are discussed.Mar 25, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ital J Pediatr. 2012 Mar 26 ;38(1):10. Epub 2012 Mar 26. PMID: 22449104
Article Published Date : Mar 25, 2012
Study Type : Review
Additional Links
Diseases : Celiac Disease, Diabetes Mellitus: Type 1
Therapeutic Actions : Dietary Modification: Wheat/Gluten Free
Additional Keywords : Genotype, Glycemic Index, HLA-DQ2/DQ8
Problem Substances : Gluten, Insulin
[+]

Insulin induces the expression of delta-5 desaturase (FADS1) in a dose-dependent manner which may explain insulin's regulation of dihomo-gamma-linoleic acid to inflammatory arachidonic acid.Jul 01, 2011

Pubmed Data : Scand J Clin Lab Invest. 2011 Jul ;71(4):330-9. Epub 2011 Mar 17. PMID: 21413848
Article Published Date : Jul 01, 2011
Study Type : In Vitro Study
Additional Links
Additional Keywords : arachidonic acid, Dose Response, High Sugar Diet, hyperinsulinemia, Inflammation, Insulin Resistance
Problem Substances : Insulin
Adverse Pharmacological Actions : Endocrine Disruptor: Insulin Resistance, Inflammatory
[+]

Oleuropein inhibits the cytotoxicity induced by amylin amyloids, a hallmark feature of type 2 diabetes.Sep 25, 2017

Pubmed Data : Biochemistry. 2017 Sep 26 ;56(38):5035-5039. Epub 2017 Sep 13. PMID: 28829122
Article Published Date : Sep 25, 2017
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids, Oleuropein
Diseases : Amyloidosis, Diabetes Mellitus: Type 2
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Insulin
[+]

Olive leaf extract protects against cytokine-induced β-cell damage through maintenance of redox homeostasis.Jun 01, 2011

Pubmed Data : Rejuvenation Res. 2011 Jun ;14(3):325-34. Epub 2011 Jul 11. PMID: 21745095
Article Published Date : Jun 01, 2011
Study Type : Plant Study
Additional Links
Substances : Oleuropein, Polyphenols
Pharmacological Actions : Apoptotic, Superoxide Dismutase Up-regulation
Additional Keywords : Cytotoxicity, Olive Leaf Extract, Plant Extracts
Problem Substances : Insulin
[+]

Puerarin may be effective in preventing islet cells from the toxic action of reactive oxygen species in diabetes.Jan 03, 2006

Pubmed Data : Eur J Pharmacol. 2006 Jan 4 ;529(1-3):1-7. PMID: 16321378
Article Published Date : Jan 03, 2006
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Hydrogen Peroxide Induced Toxicity
Pharmacological Actions : Anti-Apoptotic, Pancreato Protective Agents, Superoxide Dismutase Up-regulation
Problem Substances : Insulin
[+]

The folding pattern (conformation) of insulin analogues may contribute profoundly to their differences in toxicity and efficacy.Nov 17, 2014

Pubmed Data : Diabetes Metab. 2014 Nov 18 ;40(6):483-484. Epub 2014 Nov 18. PMID: 25459321
Article Published Date : Nov 17, 2014
Study Type : Commentary
Additional Links
Additional Keywords : Conformational State, Insulin Degludec, Insulin Glargine
Problem Substances : Insulin (Synthetically Produced)

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Insulin Doubles Death Rate in Type 2 Diabetics: Study
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A new study clearly documents that the standard treatment for type 2 diabetes is a killer, resulting in more than double the deaths. The treatment justification has always been based on irrelevant criteria - just as it is with most pharmaceutical treatments.
A Modest Dose of Ginger Improves 8 Markers of Diabetes Type 2
Written by Sayer Ji, Founder
A promising study published in the International Journal of Food Sciences and Nutrition reveals that the popular kitchen spice ginger may be an effective treatment for the prevention of diabetes and its complications
The Dangers of GMO Insulin for Type 2 Diabetics No One Talks About
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A growing body of concerning research indicates that conventional medicine's standard of care for type 2 diabetes, including synthetic insulin and oral anti-diabetic drugs, may actually increase morbidity and mortality. On the other hand, recently validated traditional approaches relying on plant-based medicines may greatly mitigate the global diabetes epidemic.
GMO Insulin Causes Type 1 Diabetes in Type 2 Diabetics, Study Finds
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A groundbreaking new study finds synthetic (GMO) insulin is capable of rapidly producing type 1 diabetes in type 2 diabetics.
Many Faces of Insulin Resistance
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Insulin resistance is a state, where cells cannot take properly sugar from blood to use it as an energy source. Cells become resistant to the action of insulin. It therefore takes more insulin to keep blood sugar in balance. People with insulin resistance syndrome will consequently have normal blood sugar levels but elevated insulin level

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