Lectins

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12 Diseases Researched for Lectins
NameACCKFocus
Thyroid Cancer110Locked
Thyroid Neoplasms110Locked
Blood-Brain-Barrier Disorders22Locked
Celiac Disease22Locked
Demyelinating Diseases12Locked
Low Immune Function: Thymus Dysfunction12Locked
Thymus Atrophy12Locked
Autoimmune Diseases11Locked
Brain: Microglial Activation11Locked
Lectin-Induced Toxicity11Locked
Osteoarthritis11Locked
Rheumatoid Arthritis11Locked

View the Evidence:
24 Abstracts with Lectins Research

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Wheat germ agglutinin (WGA) and concanavalin A bind to benign and malignant thyroid nodules.Feb 01, 1989

Pubmed Data : Arch Pathol Lab Med. 1989 Feb;113(2):186-9. PMID: 2916907
Article Published Date : Feb 01, 1989
Study Type : Human Study
Additional Links
Diseases : Thyroid Cancer, Thyroid Neoplasms
Additional Keywords : Lectins
Problem Substances : Concanavalin A, Lectins, Wheat Germ Agglutinin (WGA)
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Wheat germ agglutinin (WGA) and concanavalin bind to peripheral nerve fibres such as myelin in an animal model.Jan 01, 1996

Pubmed Data : Histochem J. 1996 Jan;28(1):7-12. PMID: 8866643
Article Published Date : Jan 01, 1996
Study Type : Animal Study
Additional Links
Diseases : Demyelinating Diseases
Additional Keywords : Lectins
Problem Substances : Concanavalin A, Lectins, Wheat Germ Agglutinin (WGA)
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Wheat germ agglutinin (WGA) exhibits anti-nutritive properties, e.g. hypertrophic growth of the pancreas and thymus atrophy.Jul 01, 1993

Pubmed Data : Br J Nutr. 1993 Jul;70(1):313-21. PMID: 8399111
Article Published Date : Jul 01, 1993
Study Type : Animal Study
Additional Links
Diseases : Low Immune Function: Thymus Dysfunction, Thymus Atrophy
Additional Keywords : Lectins, Lectins As Insecticides
Problem Substances : Lectins, Wheat Germ Agglutinin (WGA)
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Barley, rye and rice all contain chitin-binding lectins similar to wheat lectin (WGA). Jun 17, 1983

Pubmed Data : Science. 1983 Jun 17;220(4603):1290-2. PMID: 17769370
Article Published Date : Jun 17, 1983
Study Type : In Vitro Study
Additional Links
Problem Substances : Grains, Lectins, Wheat Germ Agglutinin (WGA)
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Lectins bind to inflamed synovial tissue of patients with osteoarthritis and rheumatoid arthritis.Jan 01, 1988

Pubmed Data : Acta Histochem Suppl. 1988;36:277-83. PMID: 3150561
Article Published Date : Jan 01, 1988
Study Type : In Vitro Study
Additional Links
Diseases : Osteoarthritis, Rheumatoid Arthritis
Problem Substances : Lectins, Wheat Germ Agglutinin (WGA)
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Wheat germ agglutinin (WGA) activates human neutrophils.Jul 01, 1999

Pubmed Data : Infect Immun. 1999 Jul;67(7):3461-8. PMID: 10377127
Article Published Date : Jul 01, 1999
Study Type : In Vitro Study
Additional Links
Problem Substances : Lectins, Wheat Germ Agglutinin (WGA)
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Wheat germ agglutinin (WGA) and concanavalin A can interfere with and/or modulate cellular processes.Sep 01, 1985

Pubmed Data : J Cell Physiol. 1985 Sep;124(3):474-80. PMID: 2995421
Article Published Date : Sep 01, 1985
Study Type : In Vitro Study
Additional Links
Additional Keywords : Lectins
Problem Substances : Lectins, Wheat Germ Agglutinin (WGA)
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Wheat germ agglutinin (WGA) and concanavalin A have insulin-like activity.Jan 01, 2001

Pubmed Data : Acta Biochim Pol. 2001;48(2):563-72. PMID: 11732625
Article Published Date : Jan 01, 2001
Study Type : In Vitro Study
Additional Links
Additional Keywords : Insulin Mimetic
Problem Substances : Concanavalin A, Lectins, Wheat Germ Agglutinin (WGA)
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Wheat germ agglutinin (WGA) and pertussis toxin are molecularly homologous. Jun 01, 1989

Pubmed Data : Infect Immun. 1989 Jun;57(6):1854-7. PMID: 2722243
Article Published Date : Jun 01, 1989
Study Type : In Vitro Study
Additional Links
Additional Keywords : Lectins, Molecular Mimicry
Problem Substances : Lectins, Wheat Germ Agglutinin (WGA)
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Wheat germ agglutinin (WGA) enhances the passage of native horseradish peroxidase enzyme (HRP) approximately 10 times more rapidly than HRP alone.Jun 01, 1994

Pubmed Data : J Neurochem. 1994 Jun;62(6):2404-19. PMID: 7514652
Article Published Date : Jun 01, 1994
Study Type : In Vitro Study
Additional Links
Diseases : Blood-Brain-Barrier Disorders
Problem Substances : Lectins, Wheat Germ Agglutinin (WGA)
[+]

Wheat germ agglutinin (WGA) enters through the blood-brain-barrier through adsorptive endocytosis.Jan 01, 1988

Pubmed Data : Proc Natl Acad Sci U S A. 1988 Jan;85(2):632-6. PMID: 2448779
Article Published Date : Jan 01, 1988
Study Type : In Vitro Study
Additional Links
Diseases : Blood-Brain-Barrier Disorders
Problem Substances : Lectins, Wheat Germ Agglutinin (WGA)
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Wheat germ agglutinin (WGA) has been shown to inhibit nuclear DNA replication and prevents transport into the cell nucleus.Jan 01, 1992

Pubmed Data : J Cell Sci. 1992 Jan;101 ( Pt 1):43-53. PMID: 1569128
Article Published Date : Jan 01, 1992
Study Type : In Vitro Study
Additional Links
Problem Substances : Lectins, Wheat Germ Agglutinin (WGA)
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Wheat germ agglutinin (WGA) has neuromodulatory effects - Article 2. Jan 01, 1993

Pubmed Data : Neuroscience. 1993 Jan;52(1):35-44. PMID: 7679480
Article Published Date : Jan 01, 1993
Study Type : In Vitro Study
Additional Links
Additional Keywords : Lectins
Problem Substances : Lectins, Wheat Germ Agglutinin (WGA)
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Wheat germ agglutinin (WGA) induces antibody anti-WGA formation, which may result in some cross-reactivity to other proteins.Nov 18, 1996

Pubmed Data : FEBS Lett. 1996 Nov 18;397(2-3):139-42. PMID: 8955334
Article Published Date : Nov 18, 1996
Study Type : In Vitro Study
Additional Links
Diseases : Autoimmune Diseases
Additional Keywords : Lectins
Problem Substances : Lectins, Wheat Germ Agglutinin (WGA)
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Wheat germ agglutinin (WGA) interacts with human platelets as an aggregator via fibrinogen receptors.Dec 15, 1986

Pubmed Data : Thromb Haemost. 1986 Dec 15;56(3):323-7. PMID: 3105108
Article Published Date : Dec 15, 1986
Study Type : In Vitro Study
Additional Links
Problem Substances : Lectins, Wheat Germ Agglutinin (WGA)
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Wheat germ agglutinin (WGA) is a very potent platelet stimulator. Oct 30, 2001

Pubmed Data : Biochemistry. 2001 Oct 30;40(43):12992-3001. PMID: 11669637
Article Published Date : Oct 30, 2001
Study Type : In Vitro Study
Additional Links
Additional Keywords : Lectins
Problem Substances : Lectins, Wheat Germ Agglutinin (WGA)
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Wheat germ agglutinin (WGA) is capable of blocking the inhibitory effect of nerve growth factor, in vitro. Feb 01, 1989

Pubmed Data : Cell Struct Funct. 1989 Feb;14(1):87-93. PMID: 2720800
Article Published Date : Feb 01, 1989
Study Type : In Vitro Study
Additional Links
Additional Keywords : Lectins
Problem Substances : Lectins, Wheat Germ Agglutinin (WGA)
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Wheat germ agglutinin (WGA) is capable of modifying nerve growth factor receptor properties.Dec 10, 1983

Pubmed Data : J Biol Chem. 1983 Dec 10;258(23):14136-43. PMID: 6315720
Article Published Date : Dec 10, 1983
Study Type : In Vitro Study
Additional Links
Additional Keywords : Lectins
Problem Substances : Lectins, Wheat Germ Agglutinin (WGA)
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Wheat germ agglutinin (WGA) is used as a neural network tracer due to its ease of transit through the nervous system.Jan 01, 2008

Pubmed Data : BMC Neurosci. 2008;9:96. Epub 2008 Oct 2. PMID: 18831764
Article Published Date : Jan 01, 2008
Study Type : In Vitro Study
Additional Links
Problem Substances : Lectins, Wheat Germ Agglutinin (WGA)
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Wheat germ agglutinin (WGA) lectin has neuromodulatory effects. Jul 01, 1999

Pubmed Data : Glia. 1999 Jul;27(1):53-61. PMID: 10401632
Article Published Date : Jul 01, 1999
Study Type : In Vitro Study
Additional Links
Diseases : Brain: Microglial Activation
Additional Keywords : Lectins
Problem Substances : Lectins, Wheat Germ Agglutinin (WGA)
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Wheat germ agglutinin (WGA) may be involved in the pathogenesis of celiac disease.Jan 01, 1986

Pubmed Data : Clin Exp Immunol. 1986 Jan;63(1):95-100. PMID: 3754186
Article Published Date : Jan 01, 1986
Study Type : Commentary
Additional Links
Diseases : Celiac Disease
Additional Keywords : Lectins
Problem Substances : Lectins, Wheat Germ Agglutinin (WGA)
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Wheat germ agglutinin (WGA) may be responsible for the crypt hyperplasia found in celiac children due to a mitogenic response induced by wheat germ agglutin (WGA). May 01, 1995

Pubmed Data : Pediatr Allergy Immunol. 1995 May;6(2):98-102. PMID: 7581728
Article Published Date : May 01, 1995
Study Type : Commentary
Additional Links
Diseases : Celiac Disease, Lectin-Induced Toxicity
Additional Keywords : Diseases that are Linked, Epidermal Growth Factor Mimetic
Problem Substances : Lectins, Wheat Germ Agglutinin (WGA)
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Wheat germ agglutinin blocks the biological effects of nerve growth factor.Nov 01, 1985

Pubmed Data : J Cell Biol. 1985 Nov;101(5 Pt 1):1690-4. PMID: 3840487
Article Published Date : Nov 01, 1985
Study Type : In Vitro Study
Additional Links
Additional Keywords : Lectins
Problem Substances : Lectins, Wheat Germ Agglutinin (WGA)
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Wheat germ lectin exhibits cytotoxicity. Apr 15, 2004

Pubmed Data : J Cell Biochem. 2004 Apr 15;91(6):1159-73. PMID: 15048871
Article Published Date : Apr 15, 2004
Study Type : In Vitro Study
Additional Links
Problem Substances : Lectins, Wheat Germ Agglutinin (WGA)

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The globe-spanning presence of wheat and its exalted status among secular and sacred institutions alike differentiates this food from all others presently enjoyed by humans. Yet the unparalleled rise of wheat as the very catalyst for the emergence of ancient civilization has not occurred without a great price

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