Parabens

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31 Diseases Researched for Parabens
NameACCKFocus
Bisphenol Toxicity836Locked
Parabens-Associated Toxicity 330Locked
Breast Cancer1028Locked
Infertility: Male618Locked
Prenatal Chemical Exposures415Locked
Infertility: Female212Locked
Paraben Toxicity 212Locked
Childhood Chemical Exposures110Locked
DNA damage110Locked
Diabetes Mellitus: Type 2110Locked
Fetal Origin of Adult Disease110Locked
Metabolic Syndrome X110Locked
Obesity110Locked
Ovarian Failure110Locked
Eye Damage15Locked
Uterine Cancer 35Locked
Androgen Deficiency24Locked
Testosterone: Too Low24Locked
Attention Deficit Disorder with Hyperactivity12Locked
Attention Deficit Hyperactivity Disorder12Locked
Cancers: All12Locked
Chemical Poisoning: Accumulated Environmental Toxins12Locked
Hormone Insufficency12Locked
Inflammation12Locked
Sperm Quality: Low12Locked
Breast Cancer: Chemically-Induced11Locked
Breast Cancer: Estrogen11Locked
Chemically-Induced Liver Damage11Locked
Fibroids: Uterine11Locked
Malignant Melanoma11Locked
Skin Diseases: Photo-Aging11Locked
5 Adverse Pharmacological Actions Researched for Parabens
NameACCKFocus
Genotoxic212Locked
Anti-Fertility110Locked
Neurotoxic110Locked
Estrogenic26Locked
Carcinogenic15Locked

View the Evidence:
44 Abstracts with Parabens Research

[+]

100% of male subjects tested had measurable urinary concentrations of parabens, and concentrations correlate with DNA damage in sperm. Feb 01, 2011

Pubmed Data : Environ Health Perspect. 2011 Feb ;119(2):252-7. Epub 2010 Sep 28. PMID: 20876036
Article Published Date : Feb 01, 2011
Study Type : Human Study
Additional Links
Diseases : DNA damage, Infertility: Male
Problem Substances : Parabens
Adverse Pharmacological Actions : Genotoxic
[+]

Characterization of pregnant women exposure to halogenated parabens and bisphenols through water consumption.Feb 05, 2023

Pubmed Data : J Hazard Mater. 2023 Feb 6 ;448:130945. Epub 2023 Feb 6. PMID: 36758432
Article Published Date : Feb 05, 2023
Study Type : Human Study
Additional Links
Diseases : Bisphenol Toxicity, Paraben Toxicity
Additional Keywords : Public Drinking Water
Problem Substances : Bisphenol A , Bisphenol F, Bisphenol S, Parabens
[+]

Environmental exposure to parabens might elevate blood pressure levels and increase the risk of high blood pressure.Sep 30, 2023

Pubmed Data : Chemosphere. 2023 Oct ;339:139656. Epub 2023 Jul 25. PMID: 37499807
Article Published Date : Sep 30, 2023
Study Type : Human Study
Additional Links
Diseases : Hypertension, Paraben Toxicity
Additional Keywords : Increased Risk
Problem Substances : Parabens
Adverse Pharmacological Actions : Hypertensive
[+]

Exposure to bisphenols and parabens during pregnancy and relations to steroid changes.Apr 30, 2018

Pubmed Data : Environ Res. 2018 May ;163:115-122. Epub 2018 Feb 22. PMID: 29433019
Article Published Date : Apr 30, 2018
Study Type : Human Study
Additional Links
Diseases : Bisphenol Toxicity, Paraben Toxicity
Problem Substances : Bisphenol A , Bisphenol F, Bisphenol S, Parabens
[+]

Exposure to parabens and dysglycemia: Insights from a Chinese population. Aug 16, 2023

Pubmed Data : Chemosphere. 2023 Aug 17 ;340:139868. Epub 2023 Aug 17. PMID: 37597620
Article Published Date : Aug 16, 2023
Study Type : Human Study
Additional Links
Diseases : Hyperglycemia, Paraben Toxicity
Problem Substances : Parabens
[+]

Exposure to phenols, phthalates, and parabens and development of metabolic syndrome among Mexican women in midlife.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Public Health. 2021 ;9:620769. Epub 2021 Feb 26. PMID: 33718320
Article Published Date : Dec 31, 2020
Study Type : Human Study
Additional Links
Diseases : Metabolic Syndrome X, Parabens-Associated Toxicity
Additional Keywords : Increased Risk
Problem Substances : Parabens, Phthalates
[+]

Neonates might be exposed to multiple sources of BPA and parabens in neonatal intensive care units.Oct 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Health Perspect. 2019 Nov ;127(11):117004. Epub 2019 Nov 27. PMID: 31774309
Article Published Date : Oct 31, 2019
Study Type : Human Study
Additional Links
Diseases : Bisphenol Toxicity, Parabens-Associated Toxicity
Additional Keywords : Risk Factors
Problem Substances : Bisphenol A , Parabens
[+]

Parabens are found in significant concentration in human breast tumors. Jan 01, 2004

Pubmed Data : J Appl Toxicol. 2004 Jan-Feb;24(1):5-13. PMID: 14745841
Article Published Date : Jan 01, 2004
Study Type : Human Study
Additional Links
Diseases : Breast Cancer
Problem Substances : Parabens
[+]

Prenatal exposure to certain phthalates and parabens may increase the risk for obesity in early childhood.Feb 11, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Environ Res Public Health. 2021 Feb 12 ;18(4). Epub 2021 Feb 12. PMID: 33673219
Article Published Date : Feb 11, 2021
Study Type : Human Study
Additional Links
Diseases : Obesity, Prenatal Chemical Exposures
Additional Keywords : Increased Risk
Problem Substances : Parabens, Phthalates
[+]

Propyl-paraben may be associated with diminished ovarian reserve.Aug 01, 2013

Pubmed Data : Environ Health Perspect. 2013 Aug 2. Epub 2013 Aug 2. PMID: 23912598
Article Published Date : Aug 01, 2013
Study Type : Human Study
Additional Links
Diseases : Infertility: Female, Ovarian Failure
Problem Substances : Parabens
[+]

Sunscreen and mouthwash may be important exposure sources for endocrine disrupting compounds.May 10, 2016

Pubmed Data : J Expo Sci Environ Epidemiol. 2016 May 11. Epub 2016 May 11. PMID: 27168391
Article Published Date : May 10, 2016
Study Type : Human Study
Additional Links
Additional Keywords : Mouthwash, Risk Factors
Problem Substances : Benzophenones, Endocrine Disrupting Chemicals (EDCs), Parabens, Phthalates, Sunscreen, Triclosan
[+]

This study provides greater insight into the tumorigenic role of parabens in the progression of breast cancer in Black women.Jul 02, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Endocr Soc. 2023 Jul 3 ;7(8):bvad080. Epub 2023 Jun 9. PMID: 37409182
Article Published Date : Jul 02, 2023
Study Type : Human Study
Additional Links
Diseases : Breast Cancer, Paraben Toxicity
Problem Substances : Parabens
[+]

This study provides the first evidence of associations between antimicrobials and potential adverse birth outcomes in neonates.Mar 10, 2016

Pubmed Data : J Hazard Mater. 2016 Mar 11. Epub 2016 Mar 11. PMID: 27156397
Article Published Date : Mar 10, 2016
Study Type : Human Study
Additional Links
Diseases : Fetal Origin of Adult Disease
Problem Substances : Parabens, Triclosan
Adverse Pharmacological Actions : Anti-Fertility, Neurotoxic
[+]

Urinary concentrations of environmental phenols and their association with type 2 diabetes in a population in Jeddah, Saudi Arabia.Jan 09, 2018

Pubmed Data : Environ Res. 2018 10 ;166:544-552. Epub 2018 Jun 27. PMID: 29960220
Article Published Date : Jan 09, 2018
Study Type : Human Study
Additional Links
Diseases : Bisphenol Toxicity, Diabetes Mellitus: Type 2
Additional Keywords : Increased Risk
Problem Substances : Benzophenones, Bisphenol A , Parabens
[+]

Urinary concentrations of four parabens in the U.S. population: NHANES 2005-2006.May 01, 2010

Pubmed Data : Environ Health Perspect. 2010 May ;118(5):679-85. Epub 2010 Jan 4. PMID: 20056562
Article Published Date : May 01, 2010
Study Type : Human Study
Additional Links
Diseases : Childhood Chemical Exposures, Parabens-Associated Toxicity
Problem Substances : Parabens
[+]

"Measurement of paraben concentrations in human breast tissue at serial locations across the breast from axilla to sternum."Mar 01, 2012

Pubmed Data : J Appl Toxicol. 2012 Mar ;32(3):219-32. Epub 2012 Jan 12. PMID: 22237600
Article Published Date : Mar 01, 2012
Study Type : Human In Vitro
Additional Links
Diseases : Breast Cancer
Problem Substances : Parabens
[+]

All the preservatives used in this in vitro study caused some degree of ocular tissue damage.Apr 01, 2009

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Ocul Pharmacol Ther. 2009 Apr ;25(2):113-9. PMID: 19284328
Article Published Date : Apr 01, 2009
Study Type : Human In Vitro
Additional Links
Diseases : Eye Damage
Additional Keywords : Vaccine Research
Problem Substances : Parabens, Preservatives, Thimerosal
[+]

Combinations of parabens at concentrations measured in human breast tissue can increase proliferation of MCF-7 human breast cancer cells.Apr 30, 2013

Pubmed Data : J Appl Toxicol. 2013 May ;33(5):390-8. Epub 2013 Jan 31. PMID: 23364952
Article Published Date : Apr 30, 2013
Study Type : Human In Vitro
Additional Links
Diseases : Breast Cancer
Problem Substances : Parabens
Adverse Pharmacological Actions : Carcinogenic, Estrogenic
[+]

Exposure of a postweaning mammal to butylparaben had an adverse effect on the secretion of testosterone and in the functions of the male reproductive system.Feb 01, 2001

Pubmed Data : Toxicol Ind Health. 2001 Feb;17(1):31-9. PMID: 12004923
Article Published Date : Feb 01, 2001
Study Type : Animal Study
Additional Links
Diseases : Androgen Deficiency, Infertility: Male, Testosterone: Too Low
Problem Substances : Parabens
[+]

Exposure to low-level BPA/IBP mixture in animals can decrease semen quality in adulthood.Oct 29, 2015

Pubmed Data : Hum Exp Toxicol. 2015 Oct 30. Epub 2015 Oct 30. PMID: 26519482
Article Published Date : Oct 29, 2015
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity, Infertility: Male, Paraben Toxicity
Problem Substances : Bisphenol A , Parabens
[+]

Exposure to very low doses of a mixture of chemicals induces genotoxic effects as well as monotonic cytotoxic effects in a tissue-dependent manner.Sep 11, 2019

Pubmed Data : Toxicol Lett. 2019 Sep 12. Epub 2019 Sep 12. PMID: 31521832
Article Published Date : Sep 11, 2019
Study Type : Animal Study
Additional Links
Diseases : Cancers: All, Inflammation
Additional Keywords : Increased Risk, Synergistic Toxicity
Problem Substances : Aspartame, Bisphenol A , Glyphosate, Parabens, Sodium Benzoate
Adverse Pharmacological Actions : Genotoxic
[+]

Isobutyl-parabenexposure during gestation has adverse effects on anxiety and learning abilities in offspring, especially males, and into adulthood. Oct 01, 2009

Pubmed Data : Neurosci Res. 2009 Oct;65(2):136-40. Epub 2009 Jun 26. PMID: 19560493
Article Published Date : Oct 01, 2009
Study Type : Animal Study
Additional Links
Diseases : Prenatal Chemical Exposures
Problem Substances : Parabens
[+]

Maternal exposure to butyl paraben decreases sperm number and motility in offspring. Mar 01, 2002

Pubmed Data : J Vet Med Sci. 2002 Mar;64(3):227-35. PMID: 11999442
Article Published Date : Mar 01, 2002
Study Type : Animal Study
Additional Links
Diseases : Infertility: Female, Prenatal Chemical Exposures, Sperm Quality: Low
Problem Substances : Parabens
[+]

Occurrence of and dietary exposure to parabens in foodstuffs from the United States.Apr 15, 2013

Pubmed Data : Environ Sci Technol. 2013 Apr 16 ;47(8):3918-25. Epub 2013 Apr 2. PMID: 23506043
Article Published Date : Apr 15, 2013
Study Type : Environmental
Additional Links
Diseases : Chemical Poisoning: Accumulated Environmental Toxins
Problem Substances : Parabens
[+]

Paraben exhibits uterotrphic activity in both immature and adult oavariectomized mice. Nov 01, 1997

Pubmed Data : Environ Res. 1997 Nov;75(2):130-4. PMID: 9417843
Article Published Date : Nov 01, 1997
Study Type : Animal Study
Additional Links
Diseases : Uterine Cancer
Problem Substances : Parabens
[+]

Parabens increases the proliferation of breast cancer cell lines and increases uterine weight. Jan 01, 2003

Pubmed Data : J Appl Toxicol. 2003 Jan-Feb;23(1):43-51. PMID: 12518336
Article Published Date : Jan 01, 2003
Study Type : Animal Study
Additional Links
Diseases : Breast Cancer, Uterine Cancer
Problem Substances : Parabens
[+]

Parabens may interfere with steroidogenesis. Nov 01, 2008

Pubmed Data : Toxicol Sci. 2008 Nov;106(1):206-13. Epub 2008 Jul 22. PMID: 18648085
Article Published Date : Nov 01, 2008
Study Type : Animal Study
Additional Links
Diseases : Hormone Insufficency
Problem Substances : Parabens
[+]

Prolonged exposure to a low-dose of bisphenol A increases spontaneous motor activity in adult male rats.May 07, 2013

Pubmed Data : J Physiol Sci. 2013 May 8. Epub 2013 May 8. PMID: 23653311
Article Published Date : May 07, 2013
Study Type : Animal Study
Additional Links
Diseases : Attention Deficit Disorder with Hyperactivity, Attention Deficit Hyperactivity Disorder
Problem Substances : Parabens
[+]

Propyl paraben has an adverse effect on the male reproductive system. Dec 01, 2002

Pubmed Data : Food Chem Toxicol. 2002 Dec;40(12):1807-13. PMID: 12419695
Article Published Date : Dec 01, 2002
Study Type : Animal Study
Additional Links
Diseases : Androgen Deficiency, Infertility: Male, Testosterone: Too Low
Problem Substances : Parabens
[+]

"Parabens detection in different zones of the human breast: consideration of source and implications of findings."May 01, 2012

Pubmed Data : J Appl Toxicol. 2012 May ;32(5):305-9. Epub 2012 Mar 7. PMID: 22408000
Article Published Date : May 01, 2012
Study Type : Review
Additional Links
Diseases : Breast Cancer, Breast Cancer: Estrogen
Problem Substances : Parabens
[+]

A ternary mixture of common chemicals perturbs benign human breast epithelial cells more than the same chemicals do individually.Aug 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Toxicol Sci. 2018 Sep 1 ;165(1):131-144. PMID: 29846718
Article Published Date : Aug 31, 2018
Study Type : In Vitro Study
Additional Links
Diseases : Bisphenol Toxicity, Breast Cancer: Chemically-Induced
Additional Keywords : Synergistic Toxicity
Problem Substances : Bisphenol A , Parabens, Perfluorooctanoic acid (PFOA)
[+]

Bisphenol A, 17beta-estradiol, and Parabens increase rat uterine weights. May 01, 2005

Pubmed Data : Environ Res. 2005 May;98(1):40-5. PMID: 15721882
Article Published Date : May 01, 2005
Study Type : In Vitro Study
Additional Links
Diseases : Fibroids: Uterine, Uterine Cancer
Additional Keywords : Sunscreen
Problem Substances : 17beta-estradiol, Bisphenol A , Parabens
[+]

Elevated concentrations of bisphenols, benzophenones, and antimicrobials in pantyhose collected from six countries.Jan 17, 2018

Pubmed Data : Environ Sci Technol. 2018 09 18 ;52(18):10812-10819. Epub 2018 Aug 23. PMID: 30137966
Article Published Date : Jan 17, 2018
Study Type : In Vitro Study
Additional Links
Diseases : Bisphenol Toxicity
Additional Keywords : BPA Body Burden
Problem Substances : Benzophenones, Bisphenol A , Bisphenol S, Endocrine Disrupting Chemicals (EDCs), Parabens
[+]

Endocrine disruptors, such as parabens, should be investigated as a possible contributor to increased incidence of breast cancer in women. May 01, 2004

Pubmed Data : J Appl Toxicol. 2004 May-Jun;24(3):167-76. PMID: 15211609
Article Published Date : May 01, 2004
Study Type : Review
Additional Links
Diseases : Breast Cancer
Problem Substances : Parabens
[+]

Methylparaben potentiates UV-induced damage of skin keratinocytes.Oct 03, 2006

Pubmed Data : Toxicology. 2006 Oct 3;227(1-2):62-72. Epub 2006 Jul 28. PMID: 16938376
Article Published Date : Oct 03, 2006
Study Type : In Vitro Study
Additional Links
Diseases : Skin Diseases: Photo-Aging
Problem Substances : Parabens
[+]

Paraben exposures may contribute to breast cancer, male reproductive problems and malignant melanoma. Jul 01, 2008

Pubmed Data : J Appl Toxicol. 2008 Jul;28(5):561-78. PMID: 18484575
Article Published Date : Jul 01, 2008
Study Type : Review
Additional Links
Diseases : Breast Cancer, Infertility: Male, Malignant Melanoma
Problem Substances : Parabens
[+]

Parabens exposure, especially subcutaneous and topical routes of exposure, are associated with increased risk for breast cancer. . Sep 01, 2003

Pubmed Data : J Appl Toxicol. 2003 Sep-Oct;23(5):285-8. PMID: 12975767
Article Published Date : Sep 01, 2003
Study Type : Commentary
Additional Links
Diseases : Breast Cancer
Problem Substances : Parabens
[+]

Parabens have cytotoxic effects on rat liver cells. Sep 01, 1999

Pubmed Data : Biochem Pharmacol. 1999 Sep 1;58(5):811-6. PMID: 10449191
Article Published Date : Sep 01, 1999
Study Type : In Vitro Study
Additional Links
Diseases : Chemically-Induced Liver Damage
Problem Substances : Parabens
[+]

Parabens increases proliferation in human breast cancer cell lines. Jul 01, 2005

Pubmed Data : J Appl Toxicol. 2005 Jul-Aug;25(4):301-9. PMID: 16021681
Article Published Date : Jul 01, 2005
Study Type : In Vitro Study
Additional Links
Diseases : Breast Cancer
Problem Substances : Parabens
[+]

Parabens may adversely effect mitochondrial function in the testes of men, interfering with their fertility. Jan 01, 2009

Pubmed Data : Reprod Toxicol. 2009 Jan;27(1):1-7. Epub 2008 Oct 21. PMID: 19007877
Article Published Date : Jan 01, 2009
Study Type : Commentary
Additional Links
Diseases : Infertility: Male
Problem Substances : Parabens
[+]

Parabens might be active at exposure levels not previously considered toxicologically relevant from studies testing their effects in isolation.Oct 26, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Health Perspect. 2015 Oct 27. Epub 2015 Oct 27. PMID: 26502914
Article Published Date : Oct 26, 2015
Study Type : In Vitro Study
Additional Links
Diseases : Breast Cancer
Additional Keywords : Oncogenesis Promotion
Problem Substances : Parabens
[+]

Recent findings have also shown that paraben exposure can alter bisphenol pharmacokinetics. Sep 25, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Physiol Res. 2017 Sep 26 ;66(Supplementum 3):S305-S315. PMID: 28948814
Article Published Date : Sep 25, 2017
Study Type : Review
Additional Links
Diseases : Bisphenol Toxicity, Prenatal Chemical Exposures
Problem Substances : Bisphenol A , Parabens
[+]

This is the first report in Europe on the wide presence of BPA and parabens in socks marketed for infants and children.Apr 11, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Int. 2019 Apr 12 ;127:592-600. Epub 2019 Apr 12. PMID: 30986741
Article Published Date : Apr 11, 2019
Study Type : In Vitro Study
Additional Links
Diseases : Bisphenol Toxicity
Additional Keywords : Infant Body Burden
Problem Substances : Bisphenol A , Parabens
[+]

Various compounds used in sunscreens and musks have estrogenic activity.Feb 27, 2005

Pubmed Data : J Toxicol Environ Health A. 2005 Feb 27;68(4):239-51. PMID: 15799449
Article Published Date : Feb 27, 2005
Study Type : In Vitro Study
Additional Links
Problem Substances : Homosalate, Octyl P-Dimethylaminobenzoate (PABA), Parabens, Sunscreen
Adverse Pharmacological Actions : Estrogenic

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