Perfluorinated compounds

Name	AC	CK
Perfluorinated Compound Toxicity	14	105
Prenatal Chemical Exposures	2	30
Neurodevelopmental Disorders	1	21
Chemically-Induced Liver Damage	4	16
Oxidative Stress	4	15
Attention Deficit Hyperactivity Disorder	1	10
Bisphenol-A Toxicity	1	10
Breast Cancer	1	10
Celiac Disease	1	10
Chemical Exposure	1	10
Endometriosis	1	10
Fever	1	10
Hyperlipidemia	1	10
Hyperuricemia	1	10
Impulse Control Disorders	1	10
Infertility: Male	1	10
Insulin Resistance	1	10
Leiomyoma	1	10
Phthalate Toxicity	1	10
Polycystic Ovary Syndrome	1	10
Endometrial Cancer	1	2
Fatty Liver	1	2
Infertility	1	2
Bisphenol Toxicity	1	1
Breast Cancer: Chemically-Induced	1	1
Inflammation	1	1

Name	AC	CK
Neurotoxic	2	31
Immunotoxic	2	11
Anti-Fertility	1	10
Hepatotoxic	1	10
Carcinogen	1	2
Gastrotoxic	1	1
Inflammatory	1	1

[+]

Association of prenatal exposure to perfluorinated and polyfluoroalkyl substances with childhood neurodevelopment.Jan 31, 2024

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Ecotoxicol Environ Saf. 2024 Feb ;271:115939. Epub 2024 Jan 11. PMID: 38211513

Article Published Date : Jan 31, 2024

Study Type : Meta Analysis, Review

Additional Links

Diseases : Neurodevelopmental Disorders, Perfluorinated Compound Toxicity

Problem Substances : Perfluorinated compounds

Adverse Pharmacological Actions : Neurotoxic

[+]

Early-life exposure to perfluorinated alkyl substances modulates lipid metabolism in progression to celiac disease.Aug 31, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Environ Res. 2020 Sep ;188:109864. Epub 2020 Jun 30. PMID: 32846648

Article Published Date : Aug 31, 2020

Study Type : Human Study

Additional Links

Diseases : Celiac Disease, Perfluorinated Compound Toxicity

Problem Substances : Perfluorinated compounds

[+]

Exposure to high levels of PFAS in drinking water was associated with increased risk of PCOS and possibly uterine leiomyoma.Nov 30, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Environ Int. 2021 Dec ;157:106819. Epub 2021 Aug 12. PMID: 34391986

Article Published Date : Nov 30, 2021

Study Type : Human Study

Additional Links

Diseases : Endometriosis, Leiomyoma, Perfluorinated Compound Toxicity, Polycystic Ovary Syndrome

Problem Substances : Perfluorinated compounds, Public Drinking Water

[+]

Higher serum levels of PFOA were associated with a higher prevalence of hyperuricemia.Feb 01, 2010

Click here to read the entire abstract

Pubmed Data : Environ Health Perspect. 2010 Feb;118(2):229-33. PMID: 20123605

Article Published Date : Feb 01, 2010

Study Type : Human Study

Additional Links

Diseases : Hyperuricemia

Problem Substances : Perfluorooctanoic acid (PFOA)

[+]

Internal body concentrations of endocrine disrupting chemicals are associated with an increased risk of subfertility together with alterations in hormone levels.Aug 16, 2015

Click here to read the entire abstract

Pubmed Data : Environ Int. 2015 Aug 17 ;84:154-160. Epub 2015 Aug 17. PMID: 26292060

Article Published Date : Aug 16, 2015

Study Type : Human Study

Additional Links

Diseases : Bisphenol-A Toxicity, Infertility: Male, Phthalate Toxicity

Problem Substances : Bisphenol A , Endocrine Disrupting Chemicals (EDCs), Perfluorinated compounds, Phthalates, Triclosan

Adverse Pharmacological Actions : Anti-Fertility

[+]

Perfluorinated compound exposure in children has been linked to impulse control problems. Jun 17, 2011

Click here to read the entire abstract

Pubmed Data : Environ Sci Technol. 2011 Jun 17. Epub 2011 Jun 17. PMID: 21682250

Article Published Date : Jun 17, 2011

Study Type : Human Study

Additional Links

Diseases : Attention Deficit Hyperactivity Disorder, Impulse Control Disorders

Problem Substances : Perfluorinated compounds, Perfluorooctane sulfonate (PFOS)

Adverse Pharmacological Actions : Neurotoxic

[+]

Perfluoroalkyl substances (PFASs) as risk factors for breast cancer.Sep 08, 2022

Click here to read the entire abstract

Pubmed Data : Environ Health. 2022 Sep 9 ;21(1):83. Epub 2022 Sep 9. PMID: 36085159

Article Published Date : Sep 08, 2022

Study Type : Human Study

Additional Links

Diseases : Breast Cancer, Perfluorinated Compound Toxicity

Additional Keywords : Risk Factors

Problem Substances : Perfluorinated compounds

[+]

Perfluorooctanoic acid has hepatotoxic effects.Jul 31, 2016

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Environ Health Perspect. 2016 Aug ;124(8):1227-33. Epub 2016 Mar 15. PMID: 26978841

Article Published Date : Jul 31, 2016

Study Type : Human Study

Additional Links

Diseases : Chemically-Induced Liver Damage, Perfluorinated Compound Toxicity

Problem Substances : Perfluorooctanoic acid (PFOA)

Adverse Pharmacological Actions : Hepatotoxic

[+]

Prenatal exposure to perfluoroalkyl substances led to a tendency toward increased birth weight in girls and reduced in boys.Jul 11, 2016

Click here to read the entire abstract

Pubmed Data : Reprod Toxicol. 2016 Jul 12. Epub 2016 Jul 12. PMID: 27421581

Article Published Date : Jul 11, 2016

Study Type : Human Study

Additional Links

Diseases : Perfluorinated Compound Toxicity, Prenatal Chemical Exposures

Additional Keywords : Risk Factors

Problem Substances : Endocrine Disrupting Chemicals (EDCs), Perfluorinated compounds, Perfluorooctane sulfonate (PFOS), Perfluorooctanoic acid (PFOA)

[+]

There is an association of perfluorooctanoic acid and perfluorooctane sulfonate with serum lipids among adults.Nov 15, 2009

Click here to read the entire abstract

Pubmed Data : Am J Epidemiol. 2009 Nov 15;170(10):1268-78. Epub 2009 Oct 21. PMID: 19846564

Article Published Date : Nov 15, 2009

Study Type : Human Study

Additional Links

Diseases : Hyperlipidemia

Problem Substances : Perfluorooctane sulfonate (PFOS), Perfluorooctanoic acid (PFOA)

[+]

There was statistically significant associations between selected PFAS concentrations and the locality, gender, age of donors and education level.Sep 27, 2016

Click here to read the entire abstract

Pubmed Data : Int J Hyg Environ Health. 2016 Sep 28. Epub 2016 Sep 28. PMID: 27743851

Article Published Date : Sep 27, 2016

Study Type : Human Study

Additional Links

Diseases : Chemical Exposure

Additional Keywords : chemical exposure, perfluorinated alkylated substances, Risk Factors

Problem Substances : Perfluorinated compounds, Perfluorooctane sulfonate (PFOS)

[+]

This study found a positive association between prenatal exposure to PFOS and PFOA and the prevalence of fever.Oct 31, 2016

Click here to read the entire abstract

Pubmed Data : Environ Int. 2016 Nov ;96:58-64. Epub 2016 Sep 5. PMID: 27608427

Article Published Date : Oct 31, 2016

Study Type : Human Study

Additional Links

Diseases : Fever, Prenatal Chemical Exposures

Additional Keywords : Risk Factors

Problem Substances : Perfluorinated compounds

Adverse Pharmacological Actions : Immunotoxic

[+]

Vitamin C supplementation protected against the adverse effects of perfluorooctane sulfonate and perfluorododecanoic acid which was positively associated with IR and oxidative stress.May 04, 2015

Click here to read the entire abstract

Pubmed Data : Eur J Nutr. 2015 May 5. Epub 2015 May 5. PMID: 25939797

Article Published Date : May 04, 2015

Study Type : Human Study

Additional Links

Substances : Vitamin C

Diseases : Insulin Resistance, Oxidative Stress, Perfluorinated Compound Toxicity

Pharmacological Actions : Antioxidants

Problem Substances : Perfluorinated compounds, Perfluorooctane sulfonate (PFOS)

[+]

Blueberry anthocyanins attenuated perfluorooctanoic acid induced toxicity.Jan 29, 2016

Click here to read the entire abstract

Pubmed Data : Ecotoxicol Environ Saf. 2016 Jan 30 ;127:170-174. Epub 2016 Jan 30. PMID: 26836138

Article Published Date : Jan 29, 2016

Study Type : Animal Study

Additional Links

Substances : Blueberry

Pharmacological Actions : Antioxidants, Cytoprotective

Problem Substances : Perfluorooctanoic acid

[+]

Combined effects of microplastics and chemical contaminants on the organ toxicity of zebrafish.Mar 31, 2018

Click here to read the entire abstract

Pubmed Data : Environ Res. 2018 Apr ;162:135-143. Epub 2018 Jan 4. PMID: 29306661

Article Published Date : Mar 31, 2018

Study Type : Animal Study

Additional Links

Diseases : Perfluorinated Compound Toxicity

Additional Keywords : Microplastic

Problem Substances : Perfluorinated compounds

[+]

Gastrodin attenuates perfluorooctanoic acid-induced liver injury.Jan 11, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Bioengineered. 2021 12 ;12(2):11546-11556. PMID: 34866532

Article Published Date : Jan 11, 2021

Study Type : Animal Study

Additional Links

Diseases : Chemically-Induced Liver Damage, Oxidative Stress

Pharmacological Actions : Gastrointestinal Agents, Hepatoprotective

Problem Substances : Perfluorooctanoic acid (PFOA)

[+]

Oxidative stress and PUFA alteration might help explain the sperm injury and male reproductive dysfunction induced by PFOA exposure.Aug 31, 2016

Click here to read the entire abstract

Pubmed Data : Chemosphere. 2016 Sep ;158:143-53. Epub 2016 Jun 1. PMID: 27262104

Article Published Date : Aug 31, 2016

Study Type : Animal Study

Additional Links

Diseases : Infertility, Oxidative Stress, Perfluorinated Compound Toxicity

Problem Substances : Perfluorooctanoic acid (PFOA)

[+]

Perfluorooctanoic acid (PFOA), used in the production of non-stick surface compounds, may contribute to metabolic disorders by altering mitochondrial biogenesis.Oct 01, 2009

Click here to read the entire abstract

Pubmed Data : Toxicology. 2009 Oct 1;264(1-2):10-5. Epub 2009 Jul 16. PMID: 19616056

Article Published Date : Oct 01, 2009

Study Type : Animal Study

Additional Links

Problem Substances : Nonstick cookware, Perfluorooctanoic acid (PFOA)

[+]

Rutin activates AMPKα to ameliorate liver damage caused by perfluorooctanoic acid.Jun 30, 2021

Click here to read the entire abstract

Pubmed Data : Wei Sheng Yan Jiu. 2021 Jul ;50(4):609-614. PMID: 34311832

Article Published Date : Jun 30, 2021

Study Type : Animal Study

Additional Links

Substances : Rutin

Diseases : Chemically-Induced Liver Damage

Pharmacological Actions : Antioxidants, Hepatoprotective

Problem Substances : Perfluorooctanoic acid (PFOA)

[+]

These results indicate that PFOA is a carcinogen that promotes endometrial cancer cell migration and invasion.Aug 28, 2016

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oncotarget. 2016 Aug 29. Epub 2016 Aug 29. PMID: 27589685

Article Published Date : Aug 28, 2016

Study Type : Animal Study, In Vitro Study

Additional Links

Diseases : Endometrial Cancer

Additional Keywords : Increased Risk

Problem Substances : Perfluorooctanoic acid (PFOA)

Adverse Pharmacological Actions : Carcinogen

[+]

These results suggests the potential of PFOA to cause inflammation response in liver.Mar 31, 2016

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Sci Rep. 2016 Apr 1 ;6:23963. Epub 2016 Apr 1. PMID: 27032815

Article Published Date : Mar 31, 2016

Study Type : Animal Study

Additional Links

Diseases : Chemically-Induced Liver Damage, Perfluorinated Compound Toxicity

Problem Substances : Perfluorooctanoic acid (PFOA)

[+]

This study clearly demonstrates that soil contamination of PFOA can lead to adverse effects on soil health.Jun 30, 2016

Click here to read the entire abstract

Pubmed Data : Environ Monit Assess. Jul 2016;188(7):424. Epub 2016 Jun 21. PMID: 27329475

Article Published Date : Jun 30, 2016

Study Type : Environmental

Additional Links

Diseases : Perfluorinated Compound Toxicity

Problem Substances : Perfluorooctanoic acid (PFOA)

[+]

This study showed that textiles could be a significant direct and indirect source of PFOS and PFOA exposure for both humans and the environment.Dec 31, 2015

Click here to read the entire abstract

Pubmed Data : J Environ Sci Health A Tox Hazard Subst Environ Eng. 2016 ;51(6):472-7. Epub 2016 Feb 11. PMID: 26864911

Article Published Date : Dec 31, 2015

Study Type : Environmental

Additional Links

Diseases : Perfluorinated Compound Toxicity

Additional Keywords : Environmental Pollutant, Perfluorinated Compound Toxicity, Perfluorooctane sulfonate (PFOS), Perfluorooctanoic acid (PFOA), PFOA, PFOS, Risk Factors, Toxins

Problem Substances : Perfluorinated compounds, Perfluorooctane sulfonate (PFOS), Perfluorooctanoic acid (PFOA)

[+]

Vitamin C protects the spleen against PFOA-induced immunotoxicity.Mar 19, 2023

Click here to read the entire abstract

Pubmed Data : Sci Total Environ. 2023 Mar 20 ;865:161266. Epub 2022 Dec 30. PMID: 36592905

Article Published Date : Mar 19, 2023

Study Type : Animal Study

Additional Links

Substances : Vitamin C

Diseases : Fatty Liver

Pharmacological Actions : Immunomodulatory

Problem Substances : Perfluorooctanoic acid (PFOA)

[+]

"Perfluoroalkyl acids: a review of monitoring and toxicological findings."Sep 30, 2007

Click here to read the entire abstract

Pubmed Data : Toxicol Sci. 2007 Oct ;99(2):366-94. Epub 2007 May 22. PMID: 17519394

Article Published Date : Sep 30, 2007

Study Type : Review

Additional Links

Problem Substances : Non-Stick Cookware, Perfluorinated compounds

[+]

A ternary mixture of common chemicals perturbs benign human breast epithelial cells more than the same chemicals do individually.Aug 31, 2018

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Toxicol Sci. 2018 Sep 1 ;165(1):131-144. PMID: 29846718

Article Published Date : Aug 31, 2018

Study Type : In Vitro Study

Additional Links

Diseases : Bisphenol Toxicity, Breast Cancer: Chemically-Induced

Additional Keywords : Synergistic Toxicity

Problem Substances : Bisphenol A , Parabens, Perfluorooctanoic acid (PFOA)

[+]

Blueberry anthocyanin alleviate perfluorooctanoic acid-induced toxicity.Jan 31, 2019

Click here to read the entire abstract

Pubmed Data : Environ Pollut. 2019 Feb ;245:957-964. Epub 2018 Nov 28. PMID: 30682752

Article Published Date : Jan 31, 2019

Study Type : In Vitro Study

Additional Links

Substances : Anthocyanins, Blueberry

Diseases : Oxidative Stress

Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation

Problem Substances : Perfluorooctanoic acid (PFOA)

[+]

Immunotoxicity mechanisms of perfluorinated compounds PFOA and PFOS.Feb 28, 2022

Click here to read the entire abstract

Pubmed Data : Chemosphere. 2022 Mar ;291(Pt 2):132892. Epub 2021 Nov 12. PMID: 34780734

Article Published Date : Feb 28, 2022

Study Type : Review

Additional Links

Diseases : Perfluorinated Compound Toxicity

Problem Substances : Perfluorooctane sulfonate (PFOS), Perfluorooctanoic acid (PFOA)

Adverse Pharmacological Actions : Immunotoxic

[+]

Impacts of PFOS, PFOA and their alternatives on the gut, intestinal barriers and gut-organ axis.Jul 31, 2024

Click here to read the entire abstract

Pubmed Data : Chemosphere. 2024 Aug ;361:142461. Epub 2024 May 27. PMID: 38810808

Article Published Date : Jul 31, 2024

Study Type : Review

Additional Links

Diseases : Perfluorinated Compound Toxicity

Problem Substances : Perfluorooctanoic acid (PFOA)

Adverse Pharmacological Actions : Gastrotoxic

[+]

The present data indicate that PFOA aggravated FcɛRI-mediated mast cell degranulation and allergic symptoms.Sep 28, 2016

Click here to read the entire abstract

Pubmed Data : J Appl Toxicol. 2016 Sep 29. Epub 2016 Sep 29. PMID: 27682001

Article Published Date : Sep 28, 2016

Study Type : In Vitro Study

Additional Links

Diseases : Inflammation

Problem Substances : Perfluorooctanoic acid (PFOA)

Adverse Pharmacological Actions : Inflammatory

Perfluorinated compounds jQuery(function ($) { $(".node-field-image").click(function () { $(".node-field-image").toggleClass("open"); }); $(".node.topic>.colfull").click(function () { $(".node.topic>.colfull").toggleClass("open"); }); })

Focus Your Research

Click any topic below to filter + focus research

The Following are Sub-Topics of Perfluorinated compounds

View the Evidence: 30 Abstracts with Perfluorinated compounds Research

Limited to Members Only

Currently Available Sorting Options

Association of prenatal exposure to perfluorinated and polyfluoroalkyl substances with childhood neurodevelopment.Jan 31, 2024

Early-life exposure to perfluorinated alkyl substances modulates lipid metabolism in progression to celiac disease.Aug 31, 2020

Exposure to high levels of PFAS in drinking water was associated with increased risk of PCOS and possibly uterine leiomyoma.Nov 30, 2021

Higher serum levels of PFOA were associated with a higher prevalence of hyperuricemia.Feb 01, 2010

Internal body concentrations of endocrine disrupting chemicals are associated with an increased risk of subfertility together with alterations in hormone levels.Aug 16, 2015

Perfluorinated compound exposure in children has been linked to impulse control problems. Jun 17, 2011

Perfluoroalkyl substances (PFASs) as risk factors for breast cancer.Sep 08, 2022

Perfluorooctanoic acid has hepatotoxic effects.Jul 31, 2016

Prenatal exposure to perfluoroalkyl substances led to a tendency toward increased birth weight in girls and reduced in boys.Jul 11, 2016

There is an association of perfluorooctanoic acid and perfluorooctane sulfonate with serum lipids among adults.Nov 15, 2009

There was statistically significant associations between selected PFAS concentrations and the locality, gender, age of donors and education level.Sep 27, 2016

This study found a positive association between prenatal exposure to PFOS and PFOA and the prevalence of fever.Oct 31, 2016

Vitamin C supplementation protected against the adverse effects of perfluorooctane sulfonate and perfluorododecanoic acid which was positively associated with IR and oxidative stress.May 04, 2015

Blueberry anthocyanins attenuated perfluorooctanoic acid induced toxicity.Jan 29, 2016

Combined effects of microplastics and chemical contaminants on the organ toxicity of zebrafish.Mar 31, 2018

Gastrodin attenuates perfluorooctanoic acid-induced liver injury.Jan 11, 2021

Oxidative stress and PUFA alteration might help explain the sperm injury and male reproductive dysfunction induced by PFOA exposure.Aug 31, 2016

Perfluorooctanoic acid (PFOA), used in the production of non-stick surface compounds, may contribute to metabolic disorders by altering mitochondrial biogenesis.Oct 01, 2009

Rutin activates AMPKα to ameliorate liver damage caused by perfluorooctanoic acid.Jun 30, 2021

These results indicate that PFOA is a carcinogen that promotes endometrial cancer cell migration and invasion.Aug 28, 2016

These results suggests the potential of PFOA to cause inflammation response in liver.Mar 31, 2016

This study clearly demonstrates that soil contamination of PFOA can lead to adverse effects on soil health.Jun 30, 2016

This study showed that textiles could be a significant direct and indirect source of PFOS and PFOA exposure for both humans and the environment.Dec 31, 2015

Vitamin C protects the spleen against PFOA-induced immunotoxicity.Mar 19, 2023

"Perfluoroalkyl acids: a review of monitoring and toxicological findings."Sep 30, 2007

A ternary mixture of common chemicals perturbs benign human breast epithelial cells more than the same chemicals do individually.Aug 31, 2018

Blueberry anthocyanin alleviate perfluorooctanoic acid-induced toxicity.Jan 31, 2019

Immunotoxicity mechanisms of perfluorinated compounds PFOA and PFOS.Feb 28, 2022

Impacts of PFOS, PFOA and their alternatives on the gut, intestinal barriers and gut-organ axis.Jul 31, 2024

The present data indicate that PFOA aggravated FcɛRI-mediated mast cell degranulation and allergic symptoms.Sep 28, 2016

Perfluorinated compounds Related Articles

Print Options

Perfluorinated compounds

View the Evidence:
30 Abstracts with Perfluorinated compounds Research