Perfluorooctane sulfonate (PFOS)

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12 Diseases Researched for Perfluorooctane sulfonate (PFOS)

Name	AC	CK
Perfluorinated Compound Toxicity	4	23
Attention Deficit Hyperactivity Disorder	1	10
Chemical Exposure	1	10
Hyperlipidemia	1	10
Impulse Control Disorders	1	10
Insulin Resistance	1	10
Oxidative Stress	1	10
Prenatal Chemical Exposures	1	10
Perfluorooctane Sulfonate-Induced Toxicity	3	6
Chemically-Induced Liver Damage	2	4
DNA damage	2	3
Kidney Damage: Chemically-Induced	1	2

2 Adverse Pharmacological Actions Researched for Perfluorooctane sulfonate (PFOS)

Name	AC	CK	Focus
Neurotoxic	1	10
Immunotoxic	2	3

Research Articles 13
Cumulative Knowledge Score 21
Overall Research Rating GOOD

View the Evidence:
13 Abstracts with Perfluorooctane sulfonate (PFOS) Research

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Perfluorinated compound exposure in children has been linked to impulse control problems. Jun 17, 2011

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Pubmed Data : Environ Sci Technol. 2011 Jun 17. Epub 2011 Jun 17. PMID: 21682250

Article Published Date : Jun 17, 2011

Study Type : Human Study

Additional Links

Diseases : Attention Deficit Hyperactivity Disorder, Impulse Control Disorders

Problem Substances : Perfluorinated compounds, Perfluorooctane sulfonate (PFOS)

Adverse Pharmacological Actions : Neurotoxic

[+]

Prenatal exposure to perfluoroalkyl substances led to a tendency toward increased birth weight in girls and reduced in boys.Jul 11, 2016

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Pubmed Data : Reprod Toxicol. 2016 Jul 12. Epub 2016 Jul 12. PMID: 27421581

Article Published Date : Jul 11, 2016

Study Type : Human Study

Additional Links

Diseases : Perfluorinated Compound Toxicity, Prenatal Chemical Exposures

Additional Keywords : Risk Factors

Problem Substances : Endocrine Disrupting Chemicals (EDCs), Perfluorinated compounds, Perfluorooctane sulfonate (PFOS), Perfluorooctanoic acid (PFOA)

[+]

There is an association of perfluorooctanoic acid and perfluorooctane sulfonate with serum lipids among adults.Nov 15, 2009

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Pubmed Data : Am J Epidemiol. 2009 Nov 15;170(10):1268-78. Epub 2009 Oct 21. PMID: 19846564

Article Published Date : Nov 15, 2009

Study Type : Human Study

Additional Links

Diseases : Hyperlipidemia

Problem Substances : Perfluorooctane sulfonate (PFOS), Perfluorooctanoic acid (PFOA)

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There was statistically significant associations between selected PFAS concentrations and the locality, gender, age of donors and education level.Sep 27, 2016

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Pubmed Data : Int J Hyg Environ Health. 2016 Sep 28. Epub 2016 Sep 28. PMID: 27743851

Article Published Date : Sep 27, 2016

Study Type : Human Study

Additional Links

Diseases : Chemical Exposure

Additional Keywords : chemical exposure, perfluorinated alkylated substances, Risk Factors

Problem Substances : Perfluorinated compounds, Perfluorooctane sulfonate (PFOS)

[+]

Vitamin C supplementation protected against the adverse effects of perfluorooctane sulfonate and perfluorododecanoic acid which was positively associated with IR and oxidative stress.May 04, 2015

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Pubmed Data : Eur J Nutr. 2015 May 5. Epub 2015 May 5. PMID: 25939797

Article Published Date : May 04, 2015

Study Type : Human Study

Additional Links

Substances : Vitamin C

Diseases : Insulin Resistance, Oxidative Stress, Perfluorinated Compound Toxicity

Pharmacological Actions : Antioxidants

Problem Substances : Perfluorinated compounds, Perfluorooctane sulfonate (PFOS)

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Curcumin prevents perfluorooctane sulfonate-induced genotoxicity and oxidative DNA damage in rat peripheral blood.May 06, 2015

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Pubmed Data : Drug Chem Toxicol. 2015 May 7:1-7. Epub 2015 May 7. PMID: 25950456

Article Published Date : May 06, 2015

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : DNA damage, Perfluorooctane Sulfonate-Induced Toxicity

Pharmacological Actions : Genoprotective

Problem Substances : Perfluorooctane sulfonate (PFOS)

[+]

Hepatoprotective benefits of vitamin C against perfluorooctane sulfonate-induced liver damage.Dec 04, 2018

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Pubmed Data : Environ Toxicol Pharmacol. 2018 Dec 5 ;65:60-65. Epub 2018 Dec 5. PMID: 30551094

Article Published Date : Dec 04, 2018

Study Type : Animal Study

Additional Links

Substances : Vitamin C

Diseases : Chemically-Induced Liver Damage, Perfluorooctane Sulfonate-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Fibroblast growth factor 21 upregulation, Hepatoprotective, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Problem Substances : Perfluorooctane sulfonate (PFOS)

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Naringin protects against perfluorooctane sulfonate-induced liver injury.Nov 30, 2018

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Pubmed Data : Int Immunopharmacol. 2018 Dec ;65:140-147. Epub 2018 Oct 10. PMID: 30316072

Article Published Date : Nov 30, 2018

Study Type : Animal Study

Additional Links

Substances : Citrus naringin

Diseases : Chemically-Induced Liver Damage, Perfluorooctane Sulfonate-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Problem Substances : Perfluorooctane sulfonate (PFOS)

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These results indicate that PFOS exposure can affect the immunity function in mice.Jun 30, 2009

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Pubmed Data : Arch Toxicol. 2009 Jul ;83(7):679-89. Epub 2008 Oct 21. PMID: 19015834

Article Published Date : Jun 30, 2009

Study Type : Animal Study

Additional Links

Problem Substances : Perfluorooctane sulfonate (PFOS)

Adverse Pharmacological Actions : Immunotoxic

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This provides evidence for the protective mechanism of L-carnitine in eliminating PFOS-mediated renal injury.Dec 31, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS One. 2016 ;11(5):e0155190. Epub 2016 May 12. PMID: 27171144

Article Published Date : Dec 31, 2015

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Carnitine

Diseases : Kidney Damage: Chemically-Induced

Pharmacological Actions : Renoprotective

Additional Keywords : Carnitine, Kidney Damage: Chemically-Induced, Perfluorooctane sulfonate (PFOS), Renoprotective

Problem Substances : Perfluorooctane sulfonate (PFOS)

[+]

This study showed that textiles could be a significant direct and indirect source of PFOS and PFOA exposure for both humans and the environment.Dec 31, 2015

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Pubmed Data : J Environ Sci Health A Tox Hazard Subst Environ Eng. 2016 ;51(6):472-7. Epub 2016 Feb 11. PMID: 26864911

Article Published Date : Dec 31, 2015

Study Type : Environmental

Additional Links

Diseases : Perfluorinated Compound Toxicity

Additional Keywords : Environmental Pollutant, Perfluorinated Compound Toxicity, Perfluorooctane sulfonate (PFOS), Perfluorooctanoic acid (PFOA), PFOA, PFOS, Risk Factors, Toxins

Problem Substances : Perfluorinated compounds, Perfluorooctane sulfonate (PFOS), Perfluorooctanoic acid (PFOA)

[+]

Immunotoxicity mechanisms of perfluorinated compounds PFOA and PFOS.Feb 28, 2022

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Pubmed Data : Chemosphere. 2022 Mar ;291(Pt 2):132892. Epub 2021 Nov 12. PMID: 34780734

Article Published Date : Feb 28, 2022

Study Type : Review

Additional Links

Diseases : Perfluorinated Compound Toxicity

Problem Substances : Perfluorooctane sulfonate (PFOS), Perfluorooctanoic acid (PFOA)

Adverse Pharmacological Actions : Immunotoxic

[+]

Neuroprotective effects of blueberry anthocyanins against perfluorooctanoic sulfonate.Jul 14, 2019

Click here to read the entire abstract

Pubmed Data : Ecotoxicol Environ Saf. 2019 Jul 15 ;175:39-47. Epub 2019 Mar 15. PMID: 30884343

Article Published Date : Jul 14, 2019

Study Type : In Vitro Study

Additional Links

Substances : Anthocyanins, Blueberry

Diseases : DNA damage

Pharmacological Actions : Neuroprotective Agents

Problem Substances : Perfluorooctane sulfonate (PFOS)

Research Articles 13
Cumulative Knowledge Score 21
Overall Research Rating GOOD

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Focus Your Research

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View the Evidence: 13 Abstracts with Perfluorooctane sulfonate (PFOS) Research

Limited to Members Only

Currently Available Sorting Options

Perfluorinated compound exposure in children has been linked to impulse control problems. Jun 17, 2011

Prenatal exposure to perfluoroalkyl substances led to a tendency toward increased birth weight in girls and reduced in boys.Jul 11, 2016

There is an association of perfluorooctanoic acid and perfluorooctane sulfonate with serum lipids among adults.Nov 15, 2009

There was statistically significant associations between selected PFAS concentrations and the locality, gender, age of donors and education level.Sep 27, 2016

Vitamin C supplementation protected against the adverse effects of perfluorooctane sulfonate and perfluorododecanoic acid which was positively associated with IR and oxidative stress.May 04, 2015

Curcumin prevents perfluorooctane sulfonate-induced genotoxicity and oxidative DNA damage in rat peripheral blood.May 06, 2015

Hepatoprotective benefits of vitamin C against perfluorooctane sulfonate-induced liver damage.Dec 04, 2018

Naringin protects against perfluorooctane sulfonate-induced liver injury.Nov 30, 2018

These results indicate that PFOS exposure can affect the immunity function in mice.Jun 30, 2009

This provides evidence for the protective mechanism of L-carnitine in eliminating PFOS-mediated renal injury.Dec 31, 2015

This study showed that textiles could be a significant direct and indirect source of PFOS and PFOA exposure for both humans and the environment.Dec 31, 2015

Immunotoxicity mechanisms of perfluorinated compounds PFOA and PFOS.Feb 28, 2022

Neuroprotective effects of blueberry anthocyanins against perfluorooctanoic sulfonate.Jul 14, 2019

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Perfluorooctane sulfonate (PFOS)

View the Evidence:
13 Abstracts with Perfluorooctane sulfonate (PFOS) Research