Perfluorooctanoic acid (PFOA)

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12 Diseases Researched for Perfluorooctanoic acid (PFOA)

Name	AC	CK
Perfluorinated Compound Toxicity	8	30
Chemically-Induced Liver Damage	4	16
Hyperlipidemia	1	10
Hyperuricemia	1	10
Prenatal Chemical Exposures	1	10
Oxidative Stress	3	5
Endometrial Cancer	1	2
Fatty Liver	1	2
Infertility	1	2
Bisphenol Toxicity	1	1
Breast Cancer: Chemically-Induced	1	1
Inflammation	1	1

5 Adverse Pharmacological Actions Researched for Perfluorooctanoic acid (PFOA)

Name	AC	CK
Hepatotoxic	1	10
Carcinogen	1	2
Gastrotoxic	1	1
Immunotoxic	1	1
Inflammatory	1	1

Research Articles 18
Cumulative Knowledge Score 29
Overall Research Rating GOOD

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18 Abstracts with Perfluorooctanoic acid (PFOA) Research

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Perfluorooctanoic acid (PFOA) is a Sub of the following Topic

View the Evidence: 18 Abstracts with Perfluorooctanoic acid (PFOA) Research

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Higher serum levels of PFOA were associated with a higher prevalence of hyperuricemia.Feb 01, 2010

Perfluorooctanoic acid has hepatotoxic effects.Jul 31, 2016

Prenatal exposure to perfluoroalkyl substances led to a tendency toward increased birth weight in girls and reduced in boys.Jul 11, 2016

There is an association of perfluorooctanoic acid and perfluorooctane sulfonate with serum lipids among adults.Nov 15, 2009

Gastrodin attenuates perfluorooctanoic acid-induced liver injury.Jan 11, 2021

Oxidative stress and PUFA alteration might help explain the sperm injury and male reproductive dysfunction induced by PFOA exposure.Aug 31, 2016

Perfluorooctanoic acid (PFOA), used in the production of non-stick surface compounds, may contribute to metabolic disorders by altering mitochondrial biogenesis.Oct 01, 2009

Rutin activates AMPKα to ameliorate liver damage caused by perfluorooctanoic acid.Jun 30, 2021

These results indicate that PFOA is a carcinogen that promotes endometrial cancer cell migration and invasion.Aug 28, 2016

These results suggests the potential of PFOA to cause inflammation response in liver.Mar 31, 2016

This study clearly demonstrates that soil contamination of PFOA can lead to adverse effects on soil health.Jun 30, 2016

This study showed that textiles could be a significant direct and indirect source of PFOS and PFOA exposure for both humans and the environment.Dec 31, 2015

Vitamin C protects the spleen against PFOA-induced immunotoxicity.Mar 19, 2023

A ternary mixture of common chemicals perturbs benign human breast epithelial cells more than the same chemicals do individually.Aug 31, 2018

Blueberry anthocyanin alleviate perfluorooctanoic acid-induced toxicity.Jan 31, 2019

Immunotoxicity mechanisms of perfluorinated compounds PFOA and PFOS.Feb 28, 2022

Impacts of PFOS, PFOA and their alternatives on the gut, intestinal barriers and gut-organ axis.Jul 31, 2024

The present data indicate that PFOA aggravated FcɛRI-mediated mast cell degranulation and allergic symptoms.Sep 28, 2016

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Perfluorooctanoic acid (PFOA)

View the Evidence:
18 Abstracts with Perfluorooctanoic acid (PFOA) Research