Phthalates

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97 Diseases Researched for Phthalates
NameACCKFocus
Phthalate Toxicity 100578Locked
Bisphenol Toxicity34150Locked
Prenatal Chemical Exposures21139Locked
Breast Cancer1065Locked
Insulin Resistance753Locked
Infertility: Male1047Locked
Obesity846Locked
Infant Chemical Exposures440Locked
Diabetes Mellitus: Type 2534Locked
Asthma532Locked
Neurodevelopmental Disorders431Locked
Premature Birth431Locked
Hypertension330Locked
Low Testosterone330Locked
Oxidative Stress830Locked
Hypothyroidism321Locked
Asthma: Childhood120Locked
Childhood Chemical Exposures220Locked
Puberty: Delayed120Locked
Puberty: Precocious120Locked
Infertility: Female517Locked
Prostate Cancer215Locked
Kidney Damage: Chemically-Induced314Locked
Inflammation313Locked
Testicular Injury: Chemical/Metal Induced813Locked
Atopic Dermatitis212Locked
Male Reproductive Development Abnormalities512Locked
Metabolic Diseases212Locked
Attention Deficit Hyperactivity Disorder211Locked
Bisphenol-A Toxicity211Locked
Gynecomastia211Locked
Thyroid Cancer211Locked
Thyroid Diseases211Locked
Androgen Deficiency110Locked
Atherosclerosis110Locked
Atopic Dermatitis: Infant & Childhood110Locked
Attention Deficit Disorder with Hyperactivity110Locked
Bone Diseases110Locked
Cardiovascular Diseases110Locked
Carotid Artery Narrowing110Locked
Chemical Exposure110Locked
Dengue110Locked
Depression110Locked
Eczema110Locked
Endothelial Dysfunction110Locked
Fetal Growth Retardation110Locked
Fetal Origin of Adult Disease110Locked
Fibroids: Uterine110Locked
Gestational Diabetes110Locked
Heavy Metal Toxicity110Locked
Hormone Insufficency110Locked
Infants: Low Birth Weight110Locked
Lipid Peroxidation110Locked
Metabolic Syndrome X110Locked
Nonalcoholic fatty liver disease (NAFLD)110Locked
Parabens-Associated Toxicity 110Locked
Placental Insufficiency110Locked
Polycystic Ovary Syndrome110Locked
Prediabetes110Locked
Pregnancy Complications110Locked
Sleep Disorders110Locked
Vitamin D Deficiency110Locked
Weight Problems110Locked
and obesity110Locked
High Fat Diet24Locked
Sperm Quality: Low24Locked
Testicular Diseases24Locked
Autism33Locked
Testicular Dysgenesis23Locked
Testosterone: Too Low23Locked
Allergies22Locked
Autism Spectrum Disorders22Locked
Cancer Metastasis22Locked
Cancers: All22Locked
Cardiac Surgery12Locked
Chemically-Induced Liver Damage12Locked
Dermatitis12Locked
Diabetes Mellitus: Type 122Locked
Dysbiosis12Locked
Female Reproductive Development Abnormalities12Locked
Hepatic Steatosis12Locked
High Sugar Diet12Locked
Liver Cancer12Locked
Liver Cancer: Metastatic12Locked
Respiratory Diseases12Locked
Sperm Count: Low12Locked
Thyroid Dysfunction12Locked
Triglycerides: Elevated12Locked
Autoimmune Thyroiditis11Locked
Cancers: Drug Resistant11Locked
DNA damage11Locked
Esophageal Cancer11Locked
Gastric Cancer11Locked
Hyperthyroidism11Locked
Ovarian Cancer11Locked
Premature Puberty11Locked
Premature Thelarche 11Locked
14 Adverse Pharmacological Actions Researched for Phthalates
NameACCKFocus
Diabetogenic221Locked
Immunoreactive220Locked
Cardiotoxic313Locked
Carcinogenic212Locked
Neurotoxic211Locked
Anti-Fertility110Locked
Endocrine Disruptor: Thyroid110Locked
Immunotoxic110Locked
Obesogenic23Locked
Endocrine Disruptor22Locked
Gastrotoxic12Locked
Teratogenic12Locked
Genotoxic11Locked
Tumor necrosis factorα (TNFα) up-regulation11Locked
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View the Evidence:
268 Abstracts with Phthalates Research

[+]

Association of phthalate exposure with precocious and delayed pubertal timing in girls and boys.Feb 23, 2020

Pubmed Data : Environ Sci Process Impacts. 2020 Feb 24. Epub 2020 Feb 24. PMID: 32091510
Article Published Date : Feb 23, 2020
Study Type : Meta Analysis, Review
Additional Links
Diseases : Phthalate Toxicity, Puberty: Delayed, Puberty: Precocious
Additional Keywords : Increased Risk
Problem Substances : Phthalates
[+]

Persistent and non-persistent endocrine-disrupting chemicals may affect the risk of T2D.Jun 28, 2015

Pubmed Data : J Diabetes. 2015 Jun 29. Epub 2015 Jun 29. PMID: 26119400
Article Published Date : Jun 28, 2015
Study Type : Meta Analysis, Review
Additional Links
Diseases : Diabetes Mellitus: Type 2
Problem Substances : Bisphenol A , Endocrine Disrupting Chemicals (EDCs), Pesticides, Phthalates, Polychlorinated biphenyls (PCBs)
Adverse Pharmacological Actions : Diabetogenic
[+]

Phthalate exposure and the metabolic syndrome.Sep 14, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Pollut. 2023 Sep 15 ;333:121957. Epub 2023 Jun 14. PMID: 37328121
Article Published Date : Sep 14, 2023
Study Type : Meta Analysis
Additional Links
Diseases : Metabolic Diseases, Phthalate Toxicity
Problem Substances : Phthalates
[+]

The association of bisphenol A and phthalates with risk of breast cancer.Feb 28, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Environ Res Public Health. 2021 Mar 1 ;18(5). Epub 2021 Mar 1. PMID: 33804363
Article Published Date : Feb 28, 2021
Study Type : Meta Analysis
Additional Links
Diseases : Bisphenol Toxicity, Breast Cancer
Additional Keywords : Risk Factors
Problem Substances : Bisphenol A , Phthalates
[+]

This study suggested a positive association between DEHP and BBzP exposure and childhood asthma.Jul 06, 2017

Pubmed Data : Environ Pollut. 2017 Jul 7 ;229:655-660. Epub 2017 Jul 7. PMID: 28692937
Article Published Date : Jul 06, 2017
Study Type : Meta Analysis, Review
Additional Links
Diseases : Asthma: Childhood, Phthalate Toxicity
Additional Keywords : Increased Risk
Problem Substances : Phthalates
[+]

Exposure to phthalates is associated with the occurrence of endometriosis and affects women's reproductive prognosis and ovarian function.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Cell Dev Biol. 2023 ;11:1154923. Epub 2023 Jul 25. PMID: 37560165
Article Published Date : Dec 31, 2022
Study Type : Animal Study, Human Study
Additional Links
Diseases : Endometriosis, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Urine phthalate levels were associated with skin barrier dysfunction and atopic sensitization in children Mar 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Eur Rev Med Pharmacol Sci. 2023 Apr ;27(7):2888-2898. PMID: 37070889
Article Published Date : Mar 31, 2023
Study Type : Human Study
Additional Links
Diseases : Atopic Dermatitis, Phthalate Toxicity
Problem Substances : Phthalates
[+]

"Circulating levels of bisphenol A and phthalates are related to carotid atherosclerosis in the elderly."Sep 01, 2011

Pubmed Data : Atherosclerosis. 2011 Sep ;218(1):207-13. Epub 2011 May 10. PMID: 21621210
Article Published Date : Sep 01, 2011
Study Type : Human Study
Additional Links
Diseases : Atherosclerosis, Carotid Artery Narrowing
Problem Substances : Bisphenol A , Phthalates
Adverse Pharmacological Actions : Cardiotoxic
[+]

A study of the relationship between phthalate exposure and the occurrence of adult asthma.Jul 04, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2023 Jul 5 ;28(13). Epub 2023 Jul 5. PMID: 37446892
Article Published Date : Jul 04, 2023
Study Type : Human Study
Additional Links
Diseases : Asthma, Phthalate Toxicity
Additional Keywords : Increased Risk
Problem Substances : Phthalates
[+]

Association between phthalate exposure and blood pressure during pregnancy.Nov 19, 2019

Pubmed Data : Ecotoxicol Environ Saf. 2019 Nov 20:109944. Epub 2019 Nov 20. PMID: 31757513
Article Published Date : Nov 19, 2019
Study Type : Human Study
Additional Links
Diseases : Hypertension, Phthalate Toxicity
Additional Keywords : Risk Factors
Problem Substances : Phthalates
[+]

Association between phthalates and sleep problems in the U.S. adult females.Mar 26, 2023

Pubmed Data : Int J Environ Health Res. 2023 Mar 27:1-16. Epub 2023 Mar 27. PMID: 36973994
Article Published Date : Mar 26, 2023
Study Type : Human Study
Additional Links
Diseases : Phthalate Toxicity, Sleep Disorders
Problem Substances : Phthalates
[+]

Association of phthalate exposure with pulmonary function in adults.Aug 22, 2023

Pubmed Data : Environ Res. 2023 Aug 23 ;237(Pt 2):116902. Epub 2023 Aug 23. PMID: 37625539
Article Published Date : Aug 22, 2023
Study Type : Human Study
Additional Links
Diseases : Lung Damage, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Association of urinary phthalate metabolites with all-cause and cardiovascular disease mortality among adults with diabetes mellitus.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Public Health. 2023 ;11:1178057. Epub 2023 May 30. PMID: 37325320
Article Published Date : Dec 31, 2022
Study Type : Human Study
Additional Links
Diseases : All-Cause Mortality, Cardiac Mortality , Cardiovascular Diseases, Phthalate Toxicity
Additional Keywords : Risk Factors
Problem Substances : Phthalates
[+]

Associations between exposure to phthalates and subclinical hypothyroidism in pregnant women during early pregnancy.Jan 11, 2023

Pubmed Data : Environ Pollut. 2023 Jan 12:121051. Epub 2023 Jan 12. PMID: 36642176
Article Published Date : Jan 11, 2023
Study Type : Human Study
Additional Links
Diseases : Hypothyroidism, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Associations of phthalates with prostate cancer among the US population.Jan 12, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Reprod Toxicol. 2023 Jan 13:108337. Epub 2023 Jan 13. PMID: 36646329
Article Published Date : Jan 12, 2023
Study Type : Human Study
Additional Links
Diseases : Phthalate Toxicity, Prostate Cancer
Additional Keywords : Risk Factors
Problem Substances : Phthalates
[+]

Associations of prenatal exposure to phthalates with measures of cognition in 7.5-month-old infants.Mar 07, 2021

Pubmed Data : Neurotoxicology. 2021 Mar 8 ;84:84-95. Epub 2021 Mar 8. PMID: 33705789
Article Published Date : Mar 07, 2021
Study Type : Human Study
Additional Links
Diseases : Phthalate Toxicity, Prenatal Chemical Exposures
Problem Substances : Phthalates
[+]

Associations of urinary phthalate metabolites and lipid peroxidation with sperm mitochondrial DNA copy number and deletions.Feb 04, 2018

Pubmed Data : Environ Res. 2018 Feb 5 ;163:10-15. Epub 2018 Feb 5. PMID: 29421168
Article Published Date : Feb 04, 2018
Study Type : Human Study
Additional Links
Diseases : Infertility: Male, Lipid Peroxidation
Problem Substances : Phthalates
[+]

Bisphenol A and pthalate exposure may adversely affect thyroid function. Jul 11, 2011

Pubmed Data : Environ Health Perspect. 2011 Jul 11. Epub 2011 Jul 11. PMID: 21749963
Article Published Date : Jul 11, 2011
Study Type : Human Study
Additional Links
Diseases : Hypothyroidism, Thyroid Diseases
Problem Substances : Bisphenol A , Phthalates
Adverse Pharmacological Actions : Endocrine Disruptor: Thyroid
[+]

BPA was positively associated with the relationship problems subscale at 3 y Sep 14, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Health Perspect. 2017 Sep 15 ;125(9):097014. Epub 2017 Sep 15. PMID: 28937960
Article Published Date : Sep 14, 2017
Study Type : Human Study
Additional Links
Diseases : Prenatal Chemical Exposures
Problem Substances : Bisphenol A , Phthalates
[+]

Butyl-benzyl-phthalate has a critical impact on the etiology of major depressive disorder disorder in Mexican patients.Feb 01, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Environ Res Public Health. 2022 Feb 2 ;19(3). Epub 2022 Feb 2. PMID: 35162759
Article Published Date : Feb 01, 2022
Study Type : Human Study
Additional Links
Diseases : Bisphenol Toxicity, Phthalate Toxicity
Problem Substances : Bisphenol A , Phthalates
[+]

Child exposure to phthalates may contribute to ADHD, ODD and externalizing and internalizing behaviour problems.Sep 30, 2017

Pubmed Data : Environ Pollut. 2017 Oct ;229:375-385. Epub 2017 Jun 12. PMID: 28614761
Article Published Date : Sep 30, 2017
Study Type : Human Study
Additional Links
Diseases : Attention Deficit Disorder with Hyperactivity, Phthalate Toxicity
Additional Keywords : Risk Factors
Problem Substances : Phthalates
[+]

Combined phthalates influence on glucose and lipid metabolism may increase the possibility for NAFLD and insulin resistance development.Dec 05, 2019

Pubmed Data : Environ Sci Pollut Res Int. 2019 Dec 6. Epub 2019 Dec 6. PMID: 31808097
Article Published Date : Dec 05, 2019
Study Type : Human Study
Additional Links
Diseases : Insulin Resistance, Nonalcoholic fatty liver disease (NAFLD), Phthalate Toxicity
Additional Keywords : Increased Risk
Problem Substances : Phthalates
[+]

Consumer practices represent the substantial source of phthalate exposure in Slovak children.Feb 28, 2017

Pubmed Data : Rev Environ Health. 2017 Mar 1 ;32(1-2):211-214. PMID: 28231065
Article Published Date : Feb 28, 2017
Study Type : Human Study
Additional Links
Diseases : Phthalate Toxicity
Problem Substances : Margarine, Phthalates
[+]

Cumulative risk assessment of phthalates associated with birth outcomes in pregnant Chinese women.Feb 28, 2017

Pubmed Data : Environ Pollut. 2017 Mar ;222:549-556. Epub 2016 Dec 23. PMID: 28024814
Article Published Date : Feb 28, 2017
Study Type : Human Study
Additional Links
Diseases : Infants: Low Birth Weight, Phthalate Toxicity
Problem Substances : Phthalates
[+]

DEHP and DBP could be risk factors for asthma.Mar 31, 2017

Pubmed Data : Int J Hyg Environ Health. 2017 Apr ;220(2 Pt B):468-477. Epub 2017 Jan 30. PMID: 28174042
Article Published Date : Mar 31, 2017
Study Type : Human Study
Additional Links
Diseases : Asthma, Oxidative Stress, Phthalate Toxicity
Additional Keywords : Risk Factors
Problem Substances : Phthalates
[+]

Di(2-ethylhexyl) phthalate metabolites may alter thyroid hormone levels in men.Jul 01, 2007

Pubmed Data : Environ Health Perspect. 2007 Jul;115(7):1029-34. PMID: 17637918
Article Published Date : Jul 01, 2007
Study Type : Human Study
Additional Links
Diseases : Hypothyroidism
Problem Substances : Phthalates
[+]

Early life exposure to phthalates and the development of childhood asthma among Canadian children.Mar 06, 2021

Pubmed Data : Environ Res. 2021 Mar 7 ;197:110981. Epub 2021 Mar 7. PMID: 33691158
Article Published Date : Mar 06, 2021
Study Type : Human Study
Additional Links
Diseases : Asthma, Phthalate Toxicity
Additional Keywords : Risk Factors
Problem Substances : Phthalates
[+]

Early-life DEHP exposure alter gut microbiota of newborns and may change their immune responses in later life.Jul 25, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Chem Toxicol. 2019 Jul 26:110700. Epub 2019 Jul 26. PMID: 31356917
Article Published Date : Jul 25, 2019
Study Type : Human Study
Additional Links
Diseases : Phthalate Toxicity
Additional Keywords : Microbiota
Problem Substances : Phthalates
Adverse Pharmacological Actions : Immunoreactive
[+]

Early-life phthalate exposure was found to be associated with the behavioural characteristics of children.Jan 09, 2020

Pubmed Data : Sci Total Environ. 2020 Jan 10 ;699:134053. Epub 2019 Aug 29. PMID: 31678884
Article Published Date : Jan 09, 2020
Study Type : Human Study
Additional Links
Diseases : Attention Deficit Hyperactivity Disorder, Phthalate Toxicity
Additional Keywords : Increased Risk
Problem Substances : Phthalates
[+]

Endocrine disruptors may have a greater effect on developing organs in young children or in the unborn child.Jul 13, 2017

Pubmed Data : Environ Res. 2017 Jul 14 ;158:566-575. Epub 2017 Jul 14. PMID: 28715785
Article Published Date : Jul 13, 2017
Study Type : Human Study
Additional Links
Diseases : Bisphenol Toxicity, Prenatal Chemical Exposures
Problem Substances : Bisphenol A , Phthalates
[+]

Endocrine disruptors such as BPA could modify neuroendocrine, reproductive, and metabolic regulation favouring PCOS development in adolescents.Jun 19, 2019

Pubmed Data : Gynecol Endocrinol. 2019 Jun 20:1-4. Epub 2019 Jun 20. PMID: 31219355
Article Published Date : Jun 19, 2019
Study Type : Human Study
Additional Links
Diseases : Bisphenol Toxicity, Polycystic Ovary Syndrome
Additional Keywords : Increased Risk
Problem Substances : Bisphenol A , Phthalates
[+]

Environmental exposure to phthalates and BPA may reduce circulating levels of total 25(OH)D in adults.Sep 19, 2016

Pubmed Data : J Clin Endocrinol Metab. 2016 Sep 20:jc20162134. Epub 2016 Sep 20. PMID: 27648964
Article Published Date : Sep 19, 2016
Study Type : Human Study
Additional Links
Diseases : Bisphenol Toxicity, Vitamin D Deficiency
Additional Keywords : Risk Factors
Problem Substances : Bisphenol A , Phthalates
[+]

Exposure to Bisphenol A and phthalates metabolites in the third trimester of pregnancy and BMI trajectories.Apr 25, 2018

Pubmed Data : Pediatr Obes. 2018 Apr 26. Epub 2018 Apr 26. PMID: 29700996
Article Published Date : Apr 25, 2018
Study Type : Human Study
Additional Links
Diseases : and obesity, Phthalate Toxicity
Problem Substances : Bisphenol A , Phthalates
[+]

Exposure to bisphenol AF and diethylhexylphthalate increases susceptibility to develop differentiated thyroid cancer in patients with thyroid nodules.Feb 28, 2019

Pubmed Data : Chemosphere. 2019 Mar ;218:885-894. Epub 2018 Nov 17. PMID: 30609493
Article Published Date : Feb 28, 2019
Study Type : Human Study
Additional Links
Diseases : Thyroid Cancer
Additional Keywords : Increased Risk
Problem Substances : Bisphenols, Phthalates
[+]

Exposure to bisphenols and phthalates is associated with oxidant stress, insulin resistance, and endothelial dysfunction in children.May 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pediatr Res. 2017 Jun ;81(6):857-864. Epub 2017 Jan 18. PMID: 28099427
Article Published Date : May 31, 2017
Study Type : Human Study
Additional Links
Diseases : Endothelial Dysfunction, Insulin Resistance, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Exposure to certain phthalates may cause the placenta to become thicker and more circular.Oct 09, 2017

Pubmed Data : Environ Res. 2017 Oct 10 ;160:239-246. Epub 2017 Oct 10. PMID: 29028488
Article Published Date : Oct 09, 2017
Study Type : Human Study
Additional Links
Diseases : Phthalate Toxicity, Placental Insufficiency, Prenatal Chemical Exposures
Problem Substances : Phthalates
[+]

Exposure to diethyl phthalate is associated with increased breast cancer risk in northern Mexico. Apr 01, 2010

Pubmed Data : Environ Health Perspect. 2010 Apr;118(4):539-44. PMID: 20368132
Article Published Date : Apr 01, 2010
Study Type : Human Study
Additional Links
Diseases : Breast Cancer
Problem Substances : Phthalates
Adverse Pharmacological Actions : Carcinogenic
[+]

Exposure to environmental phthalates have the potential to alter circulating levels of thyroid hormones in pregnant women.Oct 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Health Perspect. 2016 Nov ;124(11):1808-1815. Epub 2016 Aug 6. PMID: 27152641
Article Published Date : Oct 31, 2016
Study Type : Human Study
Additional Links
Diseases : Phthalate Toxicity
Additional Keywords : Risk Factors
Problem Substances : Phthalates
[+]

Exposure to high levels of the phthalate metabolite mono-isobutyl phthalate in the prenatal period is a risk factor for atopic dermatitis.Nov 04, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Allergy Clin Immunol. 2016 Nov 5. Epub 2016 Aug 5. PMID: 27826096
Article Published Date : Nov 04, 2016
Study Type : Human Study
Additional Links
Diseases : Atopic Dermatitis: Infant & Childhood, Prenatal Chemical Exposures
Additional Keywords : Risk Factors
Problem Substances : Phthalates
Adverse Pharmacological Actions : Immunoreactive
[+]

Exposure to phenols, phthalates, and parabens and development of metabolic syndrome among Mexican women in midlife.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Public Health. 2021 ;9:620769. Epub 2021 Feb 26. PMID: 33718320
Article Published Date : Dec 31, 2020
Study Type : Human Study
Additional Links
Diseases : Metabolic Syndrome X, Parabens-Associated Toxicity
Additional Keywords : Increased Risk
Problem Substances : Parabens, Phthalates
[+]

Exposure to phthalates and bisphenol A is associated with aggravation of atopic dermatitis symptoms in children.Mar 08, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Health. 2017 Mar 9 ;16(1):24. Epub 2017 Mar 9. PMID: 28274229
Article Published Date : Mar 08, 2017
Study Type : Human Study
Additional Links
Diseases : Atopic Dermatitis
Additional Keywords : Atopic Dermatitis, Bisphenol A, Phthalates, Risk Factors
Problem Substances : Bisphenol A , Phthalates
[+]

Exposure to phthalates and bisphenol A is associated with higher risk of cardiometabolic impairment in normal weight children.May 03, 2019

Pubmed Data : Environ Sci Pollut Res Int. 2019 May 4. Epub 2019 May 4. PMID: 31055746
Article Published Date : May 03, 2019
Study Type : Human Study
Additional Links
Diseases : Bisphenol Toxicity, Obesity, Phthalate Toxicity
Problem Substances : Bisphenol A , Phthalates
[+]

Exposure to phthalates is associated with an increased prevalence of rheumatoid arthritis among adults.Sep 30, 2023

Pubmed Data : Chemosphere. 2023 Oct ;338:139472. Epub 2023 Jul 16. PMID: 37459933
Article Published Date : Sep 30, 2023
Study Type : Human Study
Additional Links
Diseases : Phthalate Toxicity, Rheumatoid Arthritis
Additional Keywords : Increased Risk
Problem Substances : Phthalates
[+]

Exposure to phthalates may possibly impair control of blood glucose and thereby predispose to pre-diabetes.Jan 14, 2018

Pubmed Data : Sci Total Environ. 2018 Jan 15 ;612:1287-1292. Epub 2017 Sep 8. PMID: 28898934
Article Published Date : Jan 14, 2018
Study Type : Human Study
Additional Links
Diseases : Insulin Resistance, Phthalate Toxicity, Prediabetes
Problem Substances : Phthalates
[+]

Exposure to select phthalates was associated with respiratory morbidity among COPD patients.May 14, 2023

Pubmed Data : Environ Res. 2023 May 15 ;225:115622. Epub 2023 Mar 7. PMID: 36894111
Article Published Date : May 14, 2023
Study Type : Human Study
Additional Links
Diseases : Chronic Obstructive Pulmonary Disease, Phthalate Toxicity
Additional Keywords : Increased Risk
Problem Substances : Phthalates
[+]

Exposure to some phthalates at 5-7 years of age might interfere with thyroid hormones and growth.Nov 20, 2016

Pubmed Data : Sci Total Environ. 2016 Nov 21. Epub 2016 Nov 21. PMID: 27884522
Article Published Date : Nov 20, 2016
Study Type : Human Study
Additional Links
Diseases : Phthalate Toxicity
Problem Substances : Phthalates
[+]

Fetal exposure to bisphenols and phthalates and childhood bone mass.Jun 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Res. 2020 Jul ;186:109602. Epub 2020 May 1. PMID: 32668547
Article Published Date : Jun 30, 2020
Study Type : Human Study
Additional Links
Diseases : Bisphenol Toxicity, Bone Diseases, Fetal Origin of Adult Disease, Phthalate Toxicity
Additional Keywords : Risk Factors
Problem Substances : Bisphenol A , Phthalates
[+]

High levels of prenatal exposure to phthalates are significantly associated with decreased skeletal muscle index among girls.Dec 11, 2019

Pubmed Data : Environ Res. 2019 Dec 12 ;182:109020. Epub 2019 Dec 12. PMID: 31863942
Article Published Date : Dec 11, 2019
Study Type : Human Study
Additional Links
Diseases : Phthalate Toxicity, Prenatal Chemical Exposures
Additional Keywords : Risk Factors
Problem Substances : Phthalates
[+]

High-level dibutyl phthalate exposure was associated with an approximately two-fold increase in the rate of estrogen receptor-positive breast cancer.Apr 16, 2019

Pubmed Data : J Clin Oncol. 2019 Apr 17:JCO1802202. Epub 2019 Apr 17. PMID: 30995175
Article Published Date : Apr 16, 2019
Study Type : Human Study
Additional Links
Diseases : Breast Cancer, Phthalate Toxicity
Additional Keywords : Increased Risk
Problem Substances : Phthalates
[+]

High-temperature soup foods in plastic packaging are associated with phthalate body burden and expression of inflammatory mRNAs.Jun 20, 2022

Pubmed Data : Environ Sci Technol. 2022 Jun 21 ;56(12):8416-8427. Epub 2022 May 18. PMID: 35584204
Article Published Date : Jun 20, 2022
Study Type : Human Study
Additional Links
Diseases : Inflammation, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Individual and joint effects of phthalates exposure on the risk of early miscarriage.Mar 22, 2023

Pubmed Data : J Expo Sci Environ Epidemiol. 2023 Mar 23. Epub 2023 Mar 23. PMID: 36959356
Article Published Date : Mar 22, 2023
Study Type : Human Study
Additional Links
Diseases : Miscarriage, Phthalate Toxicity
Additional Keywords : Risk Factors
Problem Substances : Phthalates
[+]

Induced perspiration may be useful to facilitate elimination of some potentially toxic phthalate compounds including DEHP and MEHP.Dec 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : ScientificWorldJournal. 2012 ;2012:615068. Epub 2012 Oct 31. PMID: 23213291
Article Published Date : Dec 31, 2011
Study Type : Human Study
Additional Links
Diseases : Phthalate Toxicity
Therapeutic Actions : Sweating
Pharmacological Actions : Detoxifier
Problem Substances : Phthalates
[+]

Infants in neontal intensive care units are exposured to phthlates due to the use of polyvinyl chloride plastic medical devices. Sep 01, 2006

Pubmed Data : Environ Health Perspect. 2006 Sep;114(9):1424-31. PMID: 16966100
Article Published Date : Sep 01, 2006
Study Type : Human Study
Additional Links
Diseases : Infant Chemical Exposures
Problem Substances : Phthalates
[+]

Internal body concentrations of endocrine disrupting chemicals are associated with an increased risk of subfertility together with alterations in hormone levels.Aug 16, 2015

Pubmed Data : Environ Int. 2015 Aug 17 ;84:154-160. Epub 2015 Aug 17. PMID: 26292060
Article Published Date : Aug 16, 2015
Study Type : Human Study
Additional Links
Diseases : Bisphenol-A Toxicity, Infertility: Male, Phthalate Toxicity
Problem Substances : Bisphenol A , Endocrine Disrupting Chemicals (EDCs), Perfluorinated compounds, Phthalates, Triclosan
Adverse Pharmacological Actions : Anti-Fertility
[+]

Maternal bisphenol and phthalate urine concentrations and weight gain during pregnancy.Dec 17, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Int. 2019 Dec 18 ;135:105342. Epub 2019 Dec 18. PMID: 31864031
Article Published Date : Dec 17, 2019
Study Type : Human Study
Additional Links
Diseases : Bisphenol Toxicity, Phthalate Toxicity, Pregnancy Complications, Weight Problems
Additional Keywords : Risk Factors
Problem Substances : Bisphenol A , Phthalates
[+]

Maternal exposure to DEHP during pregnancy was associated with decreased fetal growthJun 15, 2016

Pubmed Data : Environ Int. 2016 Jun 16. Epub 2016 Jun 16. PMID: 27320326
Article Published Date : Jun 15, 2016
Study Type : Human Study
Additional Links
Diseases : Fetal Growth Retardation
Additional Keywords : Risk Factors
Problem Substances : Phthalates
[+]

Maternal exposure to several EDCs was associated with adverse neurodevelopmental performances among the children aged 1-2years.Dec 15, 2017

Pubmed Data : Sci Total Environ. 2017 Dec 16 ;624:377-384. Epub 2017 Dec 16. PMID: 29258038
Article Published Date : Dec 15, 2017
Study Type : Human Study
Additional Links
Diseases : Neurodevelopmental Disorders
Problem Substances : Bisphenol A , Heavy Metals, Pesticides, Phthalates
[+]

Maternal phthalate and bisphenol urine concentrations during pregnancy and early markers of arterial health in children.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Health Perspect. 2022 04 ;130(4):47007. Epub 2022 Apr 26. PMID: 35471947
Article Published Date : Dec 31, 2021
Study Type : Human Study
Additional Links
Diseases : Bisphenol Toxicity, Phthalate Toxicity, Prenatal Chemical Exposures
Problem Substances : Bisphenol A , Phthalates
[+]

MEHP exposure was concurrently associated with lower testosterone levels in young, male adults.Mar 26, 2017

Pubmed Data : Environ Pollut. 2017 Mar 27 ;225:112-117. Epub 2017 Mar 27. PMID: 28359975
Article Published Date : Mar 26, 2017
Study Type : Human Study
Additional Links
Diseases : Insulin Resistance, Low Testosterone, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Mono-(2-ethylhexyl) phthalate promotes dengue virus infection by decreasing IL-23-mediated antiviral responses.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Immunol. 2021 ;12:599345. Epub 2021 Feb 15. PMID: 33659001
Article Published Date : Dec 31, 2020
Study Type : Human Study
Additional Links
Diseases : Dengue, Phthalate Toxicity
Additional Keywords : Increased Risk
Problem Substances : Phthalates
Adverse Pharmacological Actions : Immunotoxic
[+]

Monocarboxyisooctyl phthalate was associated with lower respiratory health after controlling for related chemical exposureOct 17, 2018

Pubmed Data : Pediatr Allergy Immunol. 2018 Oct 18. Epub 2018 Oct 18. PMID: 30338578
Article Published Date : Oct 17, 2018
Study Type : Human Study
Additional Links
Diseases : Asthma, Bisphenol Toxicity, Phthalate Toxicity, Prenatal Chemical Exposures
Additional Keywords : Risk Factors
Problem Substances : Bisphenol A , Phthalates
[+]

Nail technicians are occupationally exposed to certain phthalates, phthalate alternatives, and organophosphate esters.Dec 16, 2019

Pubmed Data : Environ Sci Technol. 2019 Dec 17 ;53(24):14630-14637. Epub 2019 Dec 4. PMID: 31736299
Article Published Date : Dec 16, 2019
Study Type : Human Study
Additional Links
Diseases : Phthalate Toxicity
Additional Keywords : Risk Factors
Problem Substances : Organophosphates, Phthalates
[+]

Newborns who undergo intensive therapeutic medical interventions are exposed to higher concentrations of phthalate than the general population. May 01, 2004

Pubmed Data : Pediatrics. 2004 May;113(5):e429-34. PMID: 15121985
Article Published Date : May 01, 2004
Study Type : Human Study
Additional Links
Diseases : Infant Chemical Exposures, Premature Birth
Problem Substances : Phthalates
[+]

Occurrence of eczema in early childhood may be influenced by prenatal exposure to certain phthalates in boys.Feb 01, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Health Perspect. 2018 Feb 2 ;126(2):027002. Epub 2018 Feb 2. PMID: 29398652
Article Published Date : Feb 01, 2018
Study Type : Human Study
Additional Links
Diseases : Eczema, Phthalate Toxicity, Prenatal Chemical Exposures
Additional Keywords : eczema, Phthalate Toxicity, Phthalates, Prenatal Chemical Exposures
Problem Substances : Phthalates
[+]

Oxidative stress mediates the associations between phthalate exposures and thyroid cancer/benign nodule risk.May 31, 2023

Pubmed Data : Environ Pollut. 2023 Jun 1 ;326:121462. Epub 2023 Mar 21. PMID: 36958664
Article Published Date : May 31, 2023
Study Type : Human Study
Additional Links
Diseases : Oxidative Stress, Phthalate Toxicity, Thyroid Cancer
Additional Keywords : Risk Factors
Problem Substances : Phthalates
[+]

Paternal and maternal preconception concentrations of some phthalate biomarkers were associated with specific aspects of child behaviour.Jul 20, 2017

Pubmed Data : Environ Res. 2017 Jul 21 ;158:720-728. Epub 2017 Jul 21. PMID: 28738300
Article Published Date : Jul 20, 2017
Study Type : Human Study
Additional Links
Diseases : Neurodevelopmental Disorders, Prenatal Chemical Exposures
Problem Substances : Phthalates
[+]

Phthalate exposure and neurodevelopmental outcomes in early school age children from Poland.Nov 30, 2019

Pubmed Data : Environ Res. 2019 Dec ;179(Pt B):108829. Epub 2019 Oct 18. PMID: 31677502
Article Published Date : Nov 30, 2019
Study Type : Human Study
Additional Links
Diseases : Neurodevelopmental Disorders, Phthalate Toxicity
Problem Substances : Phthalates
Adverse Pharmacological Actions : Neurotoxic
[+]

Phthalate exposure as measured by urinary phthalate metabolites have been linked to increased risk of preterm birth Oct 01, 2009

Pubmed Data : Environ Health Perspect. 2009 Oct;117(10):1587-92. Epub 2009 Jun 16. PMID: 20019910
Article Published Date : Oct 01, 2009
Study Type : Human Study
Additional Links
Diseases : Premature Birth, Prenatal Chemical Exposures
Problem Substances : Phthalates
[+]

Phthalate exposure enhances incidence of urinary incontinence.Apr 26, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Sci Pollut Res Int. 2022 Apr 27. Epub 2022 Apr 27. PMID: 35474427
Article Published Date : Apr 26, 2022
Study Type : Human Study
Additional Links
Diseases : Incontinence: Urinary, Phthalate Toxicity
Additional Keywords : Increased Risk
Problem Substances : Phthalates
[+]

Phthalate exposure from plastic toys may adversely effect children. Jun 01, 2002

Pubmed Data : Food Addit Contam. 2002 Jun;19(6):602-10. PMID: 12042027
Article Published Date : Jun 01, 2002
Study Type : Human Study
Additional Links
Diseases : Childhood Chemical Exposures, Infant Chemical Exposures
Problem Substances : Phthalates
[+]

Phthalate exposure increased the risk of early renal impairment in Taiwanese without type 2 diabetes mellitus.Nov 25, 2019

Pubmed Data : Int J Hyg Environ Health. 2019 Nov 26:113414. Epub 2019 Nov 26. PMID: 31784327
Article Published Date : Nov 25, 2019
Study Type : Human Study
Additional Links
Diseases : Kidney Damage: Chemically-Induced, Phthalate Toxicity
Additional Keywords : Increased Risk
Problem Substances : Phthalates
[+]

Phthalate exposure is associated with reduction in serum free testosterone. Nov 01, 2006

Pubmed Data : Environ Health Perspect. 2006 Nov;114(11):1643-8. PMID: 17107847
Article Published Date : Nov 01, 2006
Study Type : Human Study
Additional Links
Diseases : Low Testosterone
Problem Substances : Phthalates
[+]

Phthalate exposure may contribute to the development of pubertal gynecomastia. Jan 01, 2010

Pubmed Data : Pediatrics. 2010 Jan;125(1):e122-9. Epub 2009 Dec 14. PMID: 20008419
Article Published Date : Jan 01, 2010
Study Type : Human Study
Additional Links
Diseases : Childhood Chemical Exposures, Gynecomastia
Problem Substances : Phthalates
[+]

Phthalate exposure was associated with alterations of reproductive hormone levels in girls.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2017 ;12(4):e0175536. Epub 2017 Apr 14. PMID: 28410414
Article Published Date : Dec 31, 2016
Study Type : Human Study
Additional Links
Diseases : Infertility: Female
Additional Keywords : Sex Hormone-Binding Globulin
Problem Substances : Phthalates
[+]

Phthalate exposure were associated with prostate cancer occurrence in abdominally obese men.Nov 07, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Res. 2019 Nov 8:108902. Epub 2019 Nov 8. PMID: 31785779
Article Published Date : Nov 07, 2019
Study Type : Human Study
Additional Links
Diseases : Obesity, Phthalate Toxicity, Prostate Cancer
Additional Keywords : Increased Risk
Problem Substances : Phthalates
[+]

Phthalate exposures and MicroRNA expression in uterine fibroids.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Epigenet Insights. 2020 ;13:2516865720904057. Epub 2020 Feb 18. PMID: 32128507
Article Published Date : Dec 31, 2019
Study Type : Human Study
Additional Links
Diseases : Fibroids: Uterine, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Premature and critically ill neonates are exposed to phthalates in the neonatal care unit. Jul 01, 2007

Pubmed Data : MCN Am J Matern Child Nurs. 2007 Jul-Aug;32(4):244-9. PMID: 17667290
Article Published Date : Jul 01, 2007
Study Type : Human Study
Additional Links
Diseases : Infant Chemical Exposures, Premature Birth
Problem Substances : Phthalates
[+]

Prenatal concentrations of certain phthalates and outcomes at birth were modestly associated with molecular changes in fetal placental tissue during pregnancy.Apr 04, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Health. 2017 Apr 5 ;16(1):35. Epub 2017 Apr 5. PMID: 28381288
Article Published Date : Apr 04, 2017
Study Type : Human Study
Additional Links
Diseases : Phthalate Toxicity, Prenatal Chemical Exposures
Additional Keywords : Risk Factors
Problem Substances : Phthalates
[+]

Prenatal exposure to certain phthalates and parabens may increase the risk for obesity in early childhood.Feb 11, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Environ Res Public Health. 2021 Feb 12 ;18(4). Epub 2021 Feb 12. PMID: 33673219
Article Published Date : Feb 11, 2021
Study Type : Human Study
Additional Links
Diseases : Obesity, Prenatal Chemical Exposures
Additional Keywords : Increased Risk
Problem Substances : Parabens, Phthalates
[+]

Prenatal exposure to phthalates and emotional/behavioral development in young children.Aug 01, 2023

Pubmed Data : Neurotoxicology. 2023 Aug 2 ;98:39-47. Epub 2023 Aug 2. PMID: 37536470
Article Published Date : Aug 01, 2023
Study Type : Human Study
Additional Links
Diseases : Developmental Disorder: Children, Phthalate Toxicity, Prenatal Chemical Exposures
Problem Substances : Phthalates
[+]

Relationships among phthalate exposure, oxidative stress, and insulin resistance in young military soldiers.May 22, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Int. 2022 May 23 ;165:107316. Epub 2022 May 23. PMID: 35635958
Article Published Date : May 22, 2022
Study Type : Human Study
Additional Links
Diseases : Insulin Resistance, Oxidative Stress, Phthalate Toxicity
Additional Keywords : Risk Factors
Problem Substances : Phthalates
[+]

Sunscreen and mouthwash may be important exposure sources for endocrine disrupting compounds.May 10, 2016

Pubmed Data : J Expo Sci Environ Epidemiol. 2016 May 11. Epub 2016 May 11. PMID: 27168391
Article Published Date : May 10, 2016
Study Type : Human Study
Additional Links
Additional Keywords : Mouthwash, Risk Factors
Problem Substances : Benzophenones, Endocrine Disrupting Chemicals (EDCs), Parabens, Phthalates, Sunscreen, Triclosan
[+]

The consumption of some flavonoids may interact with exposure to phthalates on the risk of breast cancer.Oct 31, 2016

Pubmed Data : Environ Int. 2016 Nov ;96:167-172. Epub 2016 Aug 28. PMID: 27690147
Article Published Date : Oct 31, 2016
Study Type : Human Study
Additional Links
Substances : Flavonoids, Vegetables: All
Diseases : Breast Cancer
Pharmacological Actions : Chemopreventive
Additional Keywords : Risk Reduction
Problem Substances : Phthalates
[+]

The effects of phthalate exposure on metabolic parameters in polycystic ovary syndrome.Jan 06, 2023

Pubmed Data : Clin Chim Acta. 2023 Jan 7:117225. Epub 2023 Jan 7. PMID: 36627009
Article Published Date : Jan 06, 2023
Study Type : Human Study
Additional Links
Diseases : Phthalate Toxicity, Polycystic Ovary Syndrome
Problem Substances : Phthalates
[+]

The phthalate exposure in the first trimester might be associated with the fasting blood glucose level in the third trimesterMar 09, 2017

Pubmed Data : Zhonghua Liu Xing Bing Xue Za Zhi. 2017 Mar 10 ;38(3):388-392. PMID: 28329946
Article Published Date : Mar 09, 2017
Study Type : Human Study
Additional Links
Diseases : Phthalate Toxicity
Problem Substances : Phthalates
[+]

The present study suggests that dimethyl phthalate exposure increases the risk of high blood pressure.Jul 16, 2020

Pubmed Data : Environ Int. 2020 Jul 17 ;143:105958. Epub 2020 Jul 17. PMID: 32688158
Article Published Date : Jul 16, 2020
Study Type : Human Study
Additional Links
Diseases : Hypertension, Phthalate Toxicity
Problem Substances : Phthalates
[+]

The role of Di(2-ethylhexyl) phthalate as an exacerbating factor in chronic spontaneous urticaria.Apr 30, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Allergy Asthma Immunol Res. 2022 May ;14(3):339-343. PMID: 35557498
Article Published Date : Apr 30, 2022
Study Type : Human Study
Additional Links
Diseases : Asthma, Phthalate Toxicity, Urticaria
Additional Keywords : Increased Risk
Problem Substances : Phthalates
[+]

There was an association between total phthalate concentration and non-communicable diseases and chronic inflammation in men.Jul 03, 2017

Pubmed Data : Environ Res. 2017 Jul 4 ;158:366-372. Epub 2017 Jul 4. PMID: 28686951
Article Published Date : Jul 03, 2017
Study Type : Human Study
Additional Links
Diseases : Cardiovascular Diseases, Diabetes Mellitus: Type 2, Hypertension, Inflammation, Phthalate Toxicity
Additional Keywords : Increased Risk
Problem Substances : Phthalates
[+]

These findings suggest associations of prenatal exposure to DINP with decreased masculine play behavior in boys.Jul 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Int. 2023 Aug ;178:108029. Epub 2023 Jun 13. PMID: 37331180
Article Published Date : Jul 31, 2023
Study Type : Human Study
Additional Links
Diseases : Phthalate Toxicity, Prenatal Chemical Exposures
Problem Substances : Phthalates
[+]

These results also suggested that serum levels of phthalate metabolites are a good predictor for male infertility.Jul 10, 2020

Pubmed Data : Sci Total Environ. 2020 Jul 11 ;744:140673. Epub 2020 Jul 11. PMID: 32702538
Article Published Date : Jul 10, 2020
Study Type : Human Study
Additional Links
Diseases : Infertility: Male, Phthalate Toxicity
Problem Substances : Phthalates
[+]

These results are consistent with the hypothesis that exposure to phthalates influences thyroid function and growth hormone homeostasis.Jan 31, 2017

Pubmed Data : Environ Res. 2017 Feb ;153:63-72. Epub 2016 Nov 29. PMID: 27907809
Article Published Date : Jan 31, 2017
Study Type : Human Study
Additional Links
Diseases : Bisphenol Toxicity, Phthalate Toxicity
Problem Substances : Bisphenol A , Phthalates
[+]

These results identified associations between urinary BPA and phthalates metabolites with measures of weight status and adiposity.Apr 04, 2017

Pubmed Data : Environ Res. 2017 Apr 5 ;156:326-333. Epub 2017 Apr 5. PMID: 28390300
Article Published Date : Apr 04, 2017
Study Type : Human Study
Additional Links
Diseases : Obesity
Problem Substances : Bisphenol A , Phthalates
[+]

These results may provide evidence for the hypothesis that reductions in thyroid hormones mediate associations between early life phthalate exposures.Aug 31, 2017

Pubmed Data : Environ Int. 2017 Sep ;106:11-18. Epub 2017 May 27. PMID: 28554096
Article Published Date : Aug 31, 2017
Study Type : Human Study
Additional Links
Diseases : Phthalate Toxicity
Problem Substances : Phthalates
[+]

This provides evidence that environmental chemical exposures contribute to oxidative stress.Dec 02, 2015

Pubmed Data : Environ Res. 2015 Dec 3. Epub 2015 Dec 3. PMID: 26654562
Article Published Date : Dec 02, 2015
Study Type : Human Study
Additional Links
Diseases : Chemical Exposure, Oxidative Stress
Problem Substances : Benzophenones, Bisphenol A , Bisphenol S, Phthalates
[+]

This study reveals a more elevated occupational intake of phthalate and non-phthalate plasticizers through the indoor dust at salons than at homes.Jul 16, 2017

Pubmed Data : Environ Pollut. 2017 Jul 17 ;230:701-708. Epub 2017 Jul 17. PMID: 28728088
Article Published Date : Jul 16, 2017
Study Type : Human Study
Additional Links
Diseases : Phthalate Toxicity
Problem Substances : Phthalates
[+]

Time course of phthalate cumulative risks to male developmental health over a 27-year period.Feb 04, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Int. 2020 Feb 5 ;137:105467. Epub 2020 Feb 5. PMID: 32036120
Article Published Date : Feb 04, 2020
Study Type : Human Study
Additional Links
Diseases : Phthalate Toxicity
Problem Substances : Phthalates
[+]

Ultra-processed food consumption may increase exposure to currently used phthalates.Jan 09, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Int. 2019 10 ;131:105057. Epub 2019 Aug 6. PMID: 31398592
Article Published Date : Jan 09, 2019
Study Type : Human Study
Additional Links
Diseases : Bisphenol Toxicity, Phthalate Toxicity
Additional Keywords : Canned Food, processed food
Problem Substances : Bisphenol A , Bisphenol F, Phthalates
[+]

Unhealthy levels of phthalates and bisphenol A in mexican pregnant women with gestational diabetes. Jul 06, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2019 Jul 7 ;20(13). Epub 2019 Jul 7. PMID: 31284700
Article Published Date : Jul 06, 2019
Study Type : Human Study
Additional Links
Diseases : Gestational Diabetes, Metabolic Diseases
Additional Keywords : Risk Factors
Problem Substances : Bisphenol A , Phthalates
[+]

Urinary arsenic, pesticides, heavy metals, phthalates, polyaromatic hydrocarbons, and polyfluoroalkyl compounds are associated with sleep troubles in adults.Nov 16, 2016

Pubmed Data : Environ Sci Pollut Res Int. 2016 Nov 17. Epub 2016 Nov 17. PMID: 27858272
Article Published Date : Nov 16, 2016
Study Type : Human Study
Additional Links
Diseases : Sleep Disorders
Additional Keywords : Risk Factors
Problem Substances : Aromatic hydrocarbons, Arsenic, Heavy Metals, Pesticides, Phthalates
[+]

Urinary concentration of phthalates and bisphenol A during minipuberty is associated with reproductive hormone concentrations in infant boys.Apr 30, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Hyg Environ Health. 2023 May ;250:114166. Epub 2023 Apr 13. PMID: 37058994
Article Published Date : Apr 30, 2023
Study Type : Human Study
Additional Links
Diseases : Bisphenol Toxicity
Problem Substances : Bisphenol A , Phthalates
[+]

Urinary heavy metal, phthalates and polyaromatic hydrocarbons were associated with adult depression.Jun 30, 2015

Pubmed Data : Environ Sci Pollut Res Int. 2015 Jul 1. Epub 2015 Jul 1. PMID: 26126689
Article Published Date : Jun 30, 2015
Study Type : Human Study
Additional Links
Diseases : Depression, Heavy Metal Toxicity
Additional Keywords : Increased Risk
Problem Substances : Hydrocarbons, Phthalates
[+]

Urinary metabolites of di(2-ethylhexyl) phthalate (DEHP) are inversely associated with circulating steroid hormone levels in adult men.May 01, 2009

Pubmed Data : J Androl. 2009 May-Jun;30(3):287-97. Epub 2008 Dec 4. PMID: 19059903
Article Published Date : May 01, 2009
Study Type : Human Study
Additional Links
Diseases : Androgen Deficiency, Hormone Insufficency, Low Testosterone
Additional Keywords : Sex Hormone-Binding Globulin
Problem Substances : Phthalates
[+]

Urinary phthalate exposures and risk of breast cancer: the Multiethnic Cohort study.Apr 05, 2021

Pubmed Data : Breast Cancer Res. 2021 Apr 6 ;23(1):44. Epub 2021 Apr 6. PMID: 33823904
Article Published Date : Apr 05, 2021
Study Type : Human Study
Additional Links
Diseases : Breast Cancer, Phthalate Toxicity
Additional Keywords : Risk Factors
Problem Substances : Phthalates
[+]

Women who use four or more personal care products (perfume, deodorant, lipstick, nail polish, or hand/face cream) in the 48 h prior to providing the urine sample, geometric mean MEP concentrations were more than 4 times higher than concentrations in womenFeb 01, 2009

Pubmed Data : Environ Int. 2009 Feb;35(2):353-7. Epub 2008 Sep 27. PMID: 18824263
Article Published Date : Feb 01, 2009
Study Type : Human Study
Additional Links
Problem Substances : Phthalates
[+]

β-carotene could protect against di-2-ethylhexyl phthalate induced insulin resistance.Oct 31, 2019

Pubmed Data : Environ Res. 2019 Nov ;178:108729. Epub 2019 Sep 8. PMID: 31521963
Article Published Date : Oct 31, 2019
Study Type : Human Study
Additional Links
Substances : beta-Carotene
Diseases : Insulin Resistance, Phthalate Toxicity
Pharmacological Actions : Cytoprotective
Problem Substances : Phthalates
[+]

Endocrine disruptors present potential for disrupting the structure and maintenance of the human blood-testis barrier.Feb 25, 2016

Pubmed Data : Toxicol In Vitro. 2016 Feb 26 ;34:1-7. Epub 2016 Feb 26. PMID: 26922907
Article Published Date : Feb 25, 2016
Study Type : Human In Vitro
Additional Links
Diseases : Bisphenol Toxicity, Infertility: Male
Problem Substances : Bisphenol A , Phthalates
[+]

Face mask-A potential source of phthalate exposure for human.Jan 14, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Hazard Mater. 2022 Jan 15 ;422:126848. Epub 2021 Aug 6. PMID: 34403943
Article Published Date : Jan 14, 2022
Study Type : Human In Vitro
Additional Links
Diseases : Face Mask Harms/Ineffectiveness, Phthalate Toxicity
Additional Keywords : Risk Factors
Anti Therapeutic Actions : Face Masks: Cloth
Problem Substances : Phthalates
[+]

Prenatal bisphenol A and phthalate exposure are risk factors for male reproductive system development and cord blood sex hormone levels.Jun 02, 2019

Pubmed Data : Reprod Toxicol. 2019 Jun 3. Epub 2019 Jun 3. PMID: 31170452
Article Published Date : Jun 02, 2019
Study Type : Human In Vitro
Additional Links
Diseases : Bisphenol Toxicity, Male Reproductive Development Abnormalities, Prenatal Chemical Exposures
Problem Substances : Bisphenol A , Phthalates
[+]

The present study demonstrates preliminary information regarding the low dose proliferative effects of phthalates in prostate cancer in vitro.Dec 31, 2016

Pubmed Data : Bratisl Lek Listy. 2017 ;118(8):460-466. PMID: 29050483
Article Published Date : Dec 31, 2016
Study Type : Human In Vitro
Additional Links
Substances : Alpha-Lipoic Acid
Diseases : Phthalate Toxicity, Prostate Cancer
Problem Substances : Phthalates
[+]

Bisphenol A and Di(2-Ethylhexyl) Phthalate promote pulmonary carcinoma.Jan 14, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ecotoxicol Environ Saf. 2023 Jan 15 ;250:114496. Epub 2023 Jan 4. PMID: 36608567
Article Published Date : Jan 14, 2023
Study Type : Animal Study, In Vitro Study
Additional Links
Diseases : Bisphenol Toxicity, Lung Cancer, Phthalate Toxicity
Problem Substances : Bisphenol A , Phthalates
[+]

Administration of celery oil protected the testis against DEHP induced toxicity.Aug 31, 2014

Pubmed Data : Reprod Biol. 2014 Sep ;14(3):182-9. Epub 2014 Apr 21. PMID: 25152515
Article Published Date : Aug 31, 2014
Study Type : Animal Study
Additional Links
Substances : Celery Oil
Diseases : Phthalate Toxicity
Pharmacological Actions : Antioxidants
Additional Keywords : Plant Extracts
Problem Substances : Phthalates
[+]

Altered gut microbiota community structure and correlated immune system changes in dibutyl phthalate exposed mice.Aug 04, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ecotoxicol Environ Saf. 2023 Aug 5 ;262:115321. Epub 2023 Aug 5. PMID: 37549549
Article Published Date : Aug 04, 2023
Study Type : Animal Study
Additional Links
Diseases : Dysbiosis, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Animal evidence indicates that phthalates may adversely effect human reproductive development.Oct 01, 2008

Pubmed Data : Environ Res. 2008 Oct;108(2):168-76. PMID: 18949836
Article Published Date : Oct 01, 2008
Study Type : Animal Study
Additional Links
Problem Substances : Phthalates
[+]

Ascorbic acid ameliorates dysregulated folliculogenesis induced by mono-(2-ethylhexyl)phthalate in neonatal mouse ovaries.Aug 02, 2020

Pubmed Data : Reprod Domest Anim. 2020 Aug 3. Epub 2020 Aug 3. PMID: 32744352
Article Published Date : Aug 02, 2020
Study Type : Animal Study
Additional Links
Substances : Vitamin C
Diseases : Phthalate Toxicity
Pharmacological Actions : Antioxidants
Problem Substances : Phthalates
[+]

Celery oil seed extract ameliorated the toxicological effects of DEHP in rats.Mar 31, 2015

Pubmed Data : Toxicol Ind Health. 2015 Apr ;31(4):355-66. Epub 2013 Feb 1. PMID: 23377116
Article Published Date : Mar 31, 2015
Study Type : Animal Study
Additional Links
Substances : Celery Oil, Celery seed
Diseases : Phthalate Toxicity
Pharmacological Actions : Hepatoprotective, Hypolipidemic
Additional Keywords : Plant Extracts
Problem Substances : Phthalates
[+]

Chronic exposure to a complex EDC mixture, at environmentally relevant doses can modify reproductive parameters in female mice.Dec 31, 2017

Pubmed Data : Endocrinology. 2018 02 1 ;159(2):1050-1061. PMID: 29300862
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Diseases : Infertility: Female
Problem Substances : Endocrine Disrupting Chemicals (EDCs), Phthalates
[+]

Chronic exposure to a pollutant mixture at low doses led to tissue-specific metabolic alterations in male mice fed standard and high-fat high-sucrose diet.Mar 31, 2019

Pubmed Data : Chemosphere. 2019 Apr ;220:1187-1199. Epub 2018 Dec 26. PMID: 30722647
Article Published Date : Mar 31, 2019
Study Type : Animal Study
Additional Links
Diseases : High Fat Diet, High Sugar Diet
Additional Keywords : Synergistic Toxicity
Problem Substances : 8-tetrachlorodibenzo-p-dioxin (TCDD), Bisphenol A , Phthalates, Polychlorinated biphenyls (PCBs)
[+]

Co-exposure to BPA and DEHP enhances susceptibility of mammary tumors.Sep 14, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ecotoxicol Environ Saf. 2021 Sep 15 ;221:112453. Epub 2021 Jun 26. PMID: 34186418
Article Published Date : Sep 14, 2021
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity, Breast Cancer
Additional Keywords : Increased Risk
Problem Substances : Bisphenol A , Phthalates
[+]

Co-exposure to polystyrene microplastics and di-(2-ethylhexyl) phthalate aggravates allergic asthma.Jul 31, 2023

Pubmed Data : Toxicol Lett. 2023 Aug 1 ;384:73-85. Epub 2023 Jul 26. PMID: 37500026
Article Published Date : Jul 31, 2023
Study Type : Animal Study
Additional Links
Diseases : Asthma, Microplastic Toxicity, Phthalate Toxicity
Additional Keywords : Synergistic Toxicity
Problem Substances : Phthalates, Polystyrene nanoparticles
[+]

Curcumin and resveratrol may be useful potential agents in combating DEHP-induced testicular dysfunction.Sep 07, 2015

Pubmed Data : Gen Comp Endocrinol. 2015 Sep 8. Epub 2015 Sep 8. PMID: 26361869
Article Published Date : Sep 07, 2015
Study Type : Animal Study
Additional Links
Substances : Curcumin, Resveratrol
Diseases : Phthalate Toxicity
Pharmacological Actions : Chemoprotective Agents, Heat Shock Protein Inducer, Nrf2 activation
Additional Keywords : Gene Expression
Problem Substances : Phthalates
[+]

Curcumin decreases dibutyl phthalate-induced renal dysfunction in Kunming mice via inhibiting oxidative stress and apoptosis.Mar 16, 2021

Pubmed Data : Hum Exp Toxicol. 2021 Mar 17:9603271211001124. Epub 2021 Mar 17. PMID: 33729022
Article Published Date : Mar 16, 2021
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Kidney Damage: Chemically-Induced, Phthalate Toxicity
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Renoprotective
Problem Substances : Phthalates
[+]

Curcumin had a protective effect against the harmful impact of DEHP on the male reproductive system.Sep 30, 2014

Pubmed Data : Pharmacol Rep. 2014 Oct ;66(5):782-7. Epub 2014 Apr 30. PMID: 25149981
Article Published Date : Sep 30, 2014
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Sperm Quality: Low
Pharmacological Actions : Cytoprotective
Problem Substances : Phthalates
[+]

Curcumin suppressed phthalate-induced cell migration, invasion and epithelial-mesenchymal transition, decreased the proportion of CSC-like cells.Nov 19, 2015

Pubmed Data : J Agric Food Chem. 2015 Nov 20. Epub 2015 Nov 20. PMID: 26585812
Article Published Date : Nov 19, 2015
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Liver Cancer, Liver Cancer: Metastatic, Phthalate Toxicity
Pharmacological Actions : Anti-metastatic
Additional Keywords : Cancer Stem Cells
Problem Substances : Phthalates
Adverse Pharmacological Actions : Carcinogenic
[+]

Cytoprotective potency of naringin against di-n-butylphthalate (DBP)-induced oxidative testicular damage.Dec 12, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Naunyn Schmiedebergs Arch Pharmacol. 2023 Dec 13. Epub 2023 Dec 13. PMID: 38091078
Article Published Date : Dec 12, 2023
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Phthalate Toxicity, Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Antioxidants
Problem Substances : Phthalates
[+]

Di-(2-ethylhexyl) phthalate (DEHP) promoted hepatic lipid accumulation.Jun 30, 2023

Pubmed Data : Environ Toxicol. 2023 Jul ;38(7):1628-1640. Epub 2023 Mar 29. PMID: 36988346
Article Published Date : Jun 30, 2023
Study Type : Animal Study
Additional Links
Diseases : Inflammation, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Di-(2-ethylhexyl) phthalate aggravates fine particulate matter-induced asthma.Jan 14, 2023

Pubmed Data : Toxicology. 2023 Jan 15 ;484:153406. Epub 2022 Dec 19. PMID: 36549504
Article Published Date : Jan 14, 2023
Study Type : Animal Study
Additional Links
Diseases : Air Pollution Linked Toxicity, Asthma, Phthalate Toxicity
Additional Keywords : Risk Factors
Problem Substances : Phthalates
[+]

Di-(2-ethylhexyl) phthalate exacerbated the toxicity of polystyrene nanoplastics.Jun 30, 2022

Pubmed Data : Water Res. 2022 Jul 1 ;219:118608. Epub 2022 May 16. PMID: 35605397
Article Published Date : Jun 30, 2022
Study Type : Animal Study
Additional Links
Diseases : Microplastic Toxicity, Phthalate Toxicity
Additional Keywords : Synergistic Toxicity
Problem Substances : Phthalates, Polystyrene nanoparticles
[+]

Di-(2-ethylhexyl) phthalate exposure impairs cortical development in hESC-derived cerebral organoids.Dec 28, 2022

Pubmed Data : Sci Total Environ. 2022 Dec 29:161251. Epub 2022 Dec 29. PMID: 36587670
Article Published Date : Dec 28, 2022
Study Type : Animal Study
Additional Links
Diseases : Phthalate Toxicity, Prenatal Chemical Exposures
Problem Substances : Phthalates
[+]

Di-(2-ethylhexyl) phthalate exposure induces female reproductive toxicity.Mar 03, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Toxicol. 2021 Mar 4. Epub 2021 Mar 4. PMID: 33665894
Article Published Date : Mar 03, 2021
Study Type : Animal Study
Additional Links
Diseases : Infertility: Female, Phthalate Toxicity
Problem Substances : Phthalates
Adverse Pharmacological Actions : Gastrotoxic
[+]

Di-2-ethylhexyl phthalate (DEHP) induced lipid metabolism disorder in liver.May 06, 2022

Pubmed Data : Food Chem Toxicol. 2022 May 7 ;165:113119. Epub 2022 May 7. PMID: 35537648
Article Published Date : May 06, 2022
Study Type : Animal Study
Additional Links
Diseases : Chemically-Induced Liver Damage, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Di-2-ethylhexyl phthalate imposes acute and profound damage to spermatozoaDec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Cell Dev Biol. 2020 ;8:426. Epub 2020 Jun 30. PMID: 32695775
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Diseases : Infertility: Male, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Di-n-butyl phthalate diminishes testicular steroidogenesis.Feb 28, 2021

Pubmed Data : Reprod Fertil Dev. 2021 Mar ;33(5):319-327. PMID: 33632378
Article Published Date : Feb 28, 2021
Study Type : Animal Study
Additional Links
Diseases : Phthalate Toxicity, Testicular Injury: Chemical/Metal Induced
Problem Substances : Phthalates
[+]

Dibutyl phthalate-induced oxidative stress and apoptosis in swine testis cells and therapy of naringenin.Mar 31, 2022

Pubmed Data : Environ Toxicol. 2022 Apr 1. Epub 2022 Apr 1. PMID: 35363423
Article Published Date : Mar 31, 2022
Study Type : Animal Study
Additional Links
Substances : Naringenin
Diseases : Phthalate Toxicity, Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Anti-Apoptotic, Antioxidants
Problem Substances : Phthalates
[+]

Diisodecyl phthalate exacerbated allergic dermatitis through oxidative stress and enhanced TSLP production.Nov 17, 2016

Pubmed Data : Food Chem Toxicol. 2016 Nov 18. Epub 2016 Aug 18. PMID: 27871981
Article Published Date : Nov 17, 2016
Study Type : Animal Study
Additional Links
Diseases : Dermatitis, Phthalate Toxicity
Additional Keywords : Risk Factors
Problem Substances : Phthalates
[+]

Effect of aqueous garlic extract against di-(2-ethylhexyl) phthalate induced reproductive toxicity in male mice.Jun 06, 2022

Pubmed Data : Andrologia. 2022 Jun 7:e14480. Epub 2022 Jun 7. PMID: 35670728
Article Published Date : Jun 06, 2022
Study Type : Animal Study
Additional Links
Substances : Garlic
Diseases : Phthalate Toxicity, Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Hypolipidemic
Problem Substances : Phthalates
[+]

Effects of gestational exposure to di-n-butyl phthalate and mineral oil on testis development of the Mongolian gerbil.Jun 13, 2018

Pubmed Data : Reprod Fertil Dev. 2018 Jun 14. Epub 2018 Jun 14. PMID: 29898815
Article Published Date : Jun 13, 2018
Study Type : Animal Study
Additional Links
Diseases : Male Reproductive Development Abnormalities
Problem Substances : Mineral Oil, Phthalates
[+]

Effects of Lycium barbarum glycopeptide on renal and testicular injury induced by di(2-ethylhexyl) phthalate.Mar 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Stress Chaperones. 2022 Apr 1. Epub 2022 Apr 1. PMID: 35362893
Article Published Date : Mar 31, 2022
Study Type : Animal Study
Additional Links
Substances : Goji
Diseases : Phthalate Toxicity, Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Anti-Inflammatory Agents
Problem Substances : Phthalates
[+]

Effects of phthalates on the functions and fertility of mouse spermatozoa Mar 08, 2021

Pubmed Data : Toxicology. 2021 Mar 9 ;454:152746. Epub 2021 Mar 9. PMID: 33711355
Article Published Date : Mar 08, 2021
Study Type : Animal Study
Additional Links
Diseases : Infertility: Male, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Embryonic exposures to mono-2-ethylhexyl phthalate induce larval steatosis in zebrafish independent of Nrf2a signaling.Feb 16, 2020

Pubmed Data : J Dev Orig Health Dis. 2020 Feb 17:1-9. Epub 2020 Feb 17. PMID: 32063256
Article Published Date : Feb 16, 2020
Study Type : Animal Study
Additional Links
Diseases : Hepatic Steatosis, Phthalate Toxicity, Prenatal Chemical Exposures
Additional Keywords : Risk Factors
Problem Substances : Phthalates
[+]

Environmental chemical diethylhexyl phthalate alters intestinal microbiota community structure and metabolite profile in mice.Dec 09, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : mSystems. 2019 Dec 10 ;4(6). Epub 2019 Dec 10. PMID: 31822602
Article Published Date : Dec 09, 2019
Study Type : Animal Study
Additional Links
Diseases : Phthalate Toxicity
Problem Substances : Phthalates
[+]

Environmentally relevant exposure to dibutyl phthalate disrupts DNA damage repair gene expression in the mouse ovary.Jul 17, 2019

Pubmed Data : Biol Reprod. 2019 Jul 18. Epub 2019 Jul 18. PMID: 31318015
Article Published Date : Jul 17, 2019
Study Type : Animal Study
Additional Links
Diseases : Infertility: Female, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Exposure to DEHP reduces the hydrolysis of lipid and promotes triglyceride accumulation.Nov 03, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Environ Res Public Health. 2016 Nov 4 ;13(11). Epub 2016 Aug 4. PMID: 27827939
Article Published Date : Nov 03, 2016
Study Type : Animal Study
Additional Links
Diseases : Obesity, Triglycerides: Elevated
Additional Keywords : Risk Factors
Problem Substances : Phthalates
Adverse Pharmacological Actions : Obesogenic
[+]

Exposure to phthalates DEHP and DINP May lead to oxidative damage and lipidomic disruptions in mouse kidney.Apr 30, 2021

Pubmed Data : Chemosphere. 2021 May ;271:129740. Epub 2021 Jan 22. PMID: 33736212
Article Published Date : Apr 30, 2021
Study Type : Animal Study
Additional Links
Diseases : Kidney Damage: Chemically-Induced, Oxidative Stress, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Gestational exposure to an epidemiologically defined mixture of phthalates leads to gonadal dysfunction in mouse offspring of both sexes.Apr 22, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2019 Apr 23 ;9(1):6424. Epub 2019 Apr 23. PMID: 31015488
Article Published Date : Apr 22, 2019
Study Type : Animal Study
Additional Links
Diseases : Female Reproductive Development Abnormalities, Male Reproductive Development Abnormalities, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Ginseng could be used to alleviate the toxic effects of phthalates and bisphenol A.May 17, 2018

Pubmed Data : Environ Sci Pollut Res Int. 2018 May 18. Epub 2018 May 18. PMID: 29777495
Article Published Date : May 17, 2018
Study Type : Animal Study
Additional Links
Substances : Ginseng
Diseases : Bisphenol Toxicity
Pharmacological Actions : Cytoprotective
Problem Substances : Bisphenol A , Phthalates
[+]

Gut microbiota dysbiosis might be responsible to different toxicity caused by Di-(2-ethylhexyl) phthalate exposure in murine rodents.Feb 13, 2020

Pubmed Data : Environ Pollut. 2020 Feb 14 ;261:114164. Epub 2020 Feb 14. PMID: 32088434
Article Published Date : Feb 13, 2020
Study Type : Animal Study
Additional Links
Diseases : Dysbiosis, Phthalate Toxicity
Additional Keywords : Risk Factors
Problem Substances : Phthalates
[+]

High-fat diet may have a joint effect with DEHP on lipid metabolism disorder.Dec 04, 2019

Pubmed Data : Environ Sci Pollut Res Int. 2019 Dec 5. Epub 2019 Dec 5. PMID: 31732953
Article Published Date : Dec 04, 2019
Study Type : Animal Study
Additional Links
Diseases : High Fat Diet, Phthalate Toxicity
Additional Keywords : Increased Risk
Problem Substances : Phthalates
[+]

Interactions between microplastics and phthalate esters as affected by microplastics characteristics and solution chemistry.Dec 31, 2018

Pubmed Data : Chemosphere. 2019 Jan ;214:688-694. Epub 2018 Oct 1. PMID: 30292051
Article Published Date : Dec 31, 2018
Study Type : Environmental, In Vitro Study
Additional Links
Additional Keywords : Environmental Pollution, Microplastic
Problem Substances : Phthalates
[+]

Investigation into the protective effects of Naringenin in phthalates-induced reproductive damage.Apr 30, 2022

Pubmed Data : Eur Rev Med Pharmacol Sci. 2022 May ;26(10):3419-3429. PMID: 35647821
Article Published Date : Apr 30, 2022
Study Type : Animal Study
Additional Links
Substances : Naringenin
Diseases : Phthalate Toxicity, Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Antioxidants
Problem Substances : Phthalates
[+]

Long-term dietary administration of diethyl phthalate triggers loss of insulin sensitivity in two key insulin target tissues of mice.Mar 03, 2020

Pubmed Data : Hum Exp Toxicol. 2020 Mar 4:960327120909526. Epub 2020 Mar 4. PMID: 32129097
Article Published Date : Mar 03, 2020
Study Type : Animal Study
Additional Links
Diseases : Diabetes Mellitus: Type 2, Insulin Resistance, Metabolic Diseases, Phthalate Toxicity
Additional Keywords : Risk Factors
Problem Substances : Phthalates
[+]

Low dose of genistein alleviates phthalate-induced fetal testis disorder.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2020 ;2020:4569268. Epub 2020 May 27. PMID: 32566080
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Genistein
Diseases : Phthalate Toxicity, Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Antioxidants
Problem Substances : Phthalates
[+]

Low-dose pollutant mixture triggers metabolic disturbances in female mice.Apr 07, 2017

Pubmed Data : J Nutr Biochem. 2017 Apr 8 ;45:83-93. Epub 2017 Apr 8. PMID: 28433925
Article Published Date : Apr 07, 2017
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity
Problem Substances : 8-tetrachlorodibenzo-p-dioxin (TCDD), Bisphenol A , Phthalates
[+]

Lycium barbarum polysaccharides and Wolfberry juice prevent DEHP-induced hepatotoxicity.Feb 05, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2021 Feb 6 ;26(4). Epub 2021 Feb 6. PMID: 33562043
Article Published Date : Feb 05, 2021
Study Type : Animal Study
Additional Links
Substances : Goji
Diseases : Chemically-Induced Liver Damage, Phthalate Toxicity
Pharmacological Actions : Hepatoprotective
Additional Keywords : Polysaccharides
Problem Substances : Phthalates
[+]

Lycopene abrogates di-(2-ethylhexyl) phthalate induced testicular injury.Aug 14, 2018

Pubmed Data : Life Sci. 2018 Aug 15 ;207:265-271. Epub 2018 Jun 7. PMID: 29886059
Article Published Date : Aug 14, 2018
Study Type : Animal Study
Additional Links
Substances : Lycopene
Diseases : Inflammation, Oxidative Stress, Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Phthalates
[+]

Lycopene ameliorates DEHP exposure-induced renal pyroptosis.Jan 03, 2023

Pubmed Data : J Nutr Biochem. 2023 Jan 4:109266. Epub 2023 Jan 4. PMID: 36610486
Article Published Date : Jan 03, 2023
Study Type : Animal Study
Additional Links
Substances : Lycopene
Diseases : Kidney Damage: Chemically-Induced, Phthalate Toxicity
Pharmacological Actions : Antioxidants, Nrf2 activation, Renoprotective
Problem Substances : Phthalates
[+]

Lycopene attenuates Di(2-ethylhexyl) phthalate-induced mitochondrial damage and inflammation in kidney.Jan 10, 2023

Pubmed Data : J Agric Food Chem. 2023 Jan 11 ;71(1):569-579. Epub 2022 Dec 30. PMID: 36583613
Article Published Date : Jan 10, 2023
Study Type : Animal Study
Additional Links
Substances : Lycopene
Diseases : Inflammation, Kidney Damage: Chemically-Induced, Phthalate Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Renoprotective
Problem Substances : Phthalates
[+]

Lycopene attenuates di(2-ethylhexyl) phthalate-induced mitophagy in spleen by regulating the sirtuin3-mediated pathway.May 20, 2021

Pubmed Data : Food Funct. 2021 May 21 ;12(10):4582-4590. Epub 2021 Apr 28. PMID: 33908429
Article Published Date : May 20, 2021
Study Type : Animal Study
Additional Links
Substances : Lycopene
Diseases : Phthalate Toxicity
Pharmacological Actions : Anti-Inflammatory Agents
Problem Substances : Phthalates
[+]

Lycopene prevents DEHP-induced Leydig cell damage with the Nrf2 antioxidant signaling pathway in mice.Dec 07, 2019

Pubmed Data : J Agric Food Chem. 2019 Dec 8. Epub 2019 Dec 8. PMID: 31814398
Article Published Date : Dec 07, 2019
Study Type : Animal Study
Additional Links
Substances : Lycopene
Diseases : Infertility: Male
Pharmacological Actions : Antioxidants, Nrf2 activation
Problem Substances : Phthalates
[+]

Lycopene prevents DEHP-induced liver lipid metabolism disorder.Oct 13, 2020

Pubmed Data : J Agric Food Chem. 2020 Oct 14 ;68(41):11468-11479. Epub 2020 Oct 5. PMID: 32962341
Article Published Date : Oct 13, 2020
Study Type : Animal Study
Additional Links
Substances : Lycopene
Diseases : Chemically-Induced Liver Damage, Phthalate Toxicity
Pharmacological Actions : Hepatoprotective, Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor
Problem Substances : Phthalates
[+]

Lycopene prevents Di-(2-ethylhexyl) phthalate-induced mitophagy and oxidative stress in mice heart.Apr 30, 2023

Pubmed Data : J Nutr Biochem. 2023 May ;115:109285. Epub 2023 Feb 14. PMID: 36796548
Article Published Date : Apr 30, 2023
Study Type : Animal Study
Additional Links
Substances : Lycopene
Diseases : Mitochondrial Dysfunction , Oxidative Stress, Phthalate Toxicity
Pharmacological Actions : Antioxidants, Cardioprotective
Problem Substances : Phthalates
[+]

Lycopene prevents phthalate-Induced cognitive impairment.Oct 22, 2023

Pubmed Data : J Agric Food Chem. 2023 Oct 23. Epub 2023 Oct 23. PMID: 37871231
Article Published Date : Oct 22, 2023
Study Type : Animal Study
Additional Links
Substances : Lycopene
Diseases : Phthalate Toxicity
Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Neuroprotective Agents, Nrf2 activation
Problem Substances : Phthalates
[+]

Lycopene regulates the mitochondrial unfolded protein response to prevent DEHP-induced cardiac mitochondrial damage.Apr 19, 2022

Pubmed Data : Food Funct. 2022 Apr 20 ;13(8):4527-4536. Epub 2022 Apr 20. PMID: 35348563
Article Published Date : Apr 19, 2022
Study Type : Animal Study
Additional Links
Substances : Lycopene
Diseases : Oxidative Stress, Phthalate Toxicity
Pharmacological Actions : Antioxidants, Cardioprotective, Nrf2 activation
Problem Substances : Phthalates
[+]

Mangiferin mitigates di-(2-ethylhexyl) phthalate-induced testicular injury.Oct 29, 2021

Pubmed Data : Arch Biochem Biophys. 2021 Oct 30 ;711:108982. Epub 2021 Aug 13. PMID: 34400143
Article Published Date : Oct 29, 2021
Study Type : Animal Study
Additional Links
Substances : Mangiferin
Diseases : Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Nrf2 activation
Problem Substances : Phthalates
[+]

Maternal exposure to di-2-ethylhexyl phthalate (DEHP) depresses lactation capacity in mice.May 08, 2022

Pubmed Data : Sci Total Environ. 2022 May 9:155813. Epub 2022 May 9. PMID: 35550907
Article Published Date : May 08, 2022
Study Type : Animal Study
Additional Links
Diseases : Inflammation, Oxidative Stress, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Maternal exposure to phthalate during fetal and/or neonatal periods increase the incidence of atopic dermatitis in male offspring. Sep 01, 2008

Pubmed Data : Environ Health Perspect. 2008 Sep;116(9):1136-41. PMID: 18795153
Article Published Date : Sep 01, 2008
Study Type : Animal Study
Additional Links
Diseases : Atopic Dermatitis, Prenatal Chemical Exposures
Problem Substances : Phthalates
[+]

Melatonin protects prepuberal testis from deleterious effects of bisphenol A or diethylhexyl phthalate.Apr 13, 2018

Pubmed Data : J Pineal Res. 2018 Apr 14:e12497. Epub 2018 Apr 14. PMID: 29655234
Article Published Date : Apr 13, 2018
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Bisphenol Toxicity, Testicular Injury: Chemical/Metal Induced
Problem Substances : Bisphenol A , Phthalates
[+]

Multi-strain probiotic ameliorated toxic effects of phthalates and bisphenol A mixture.Jul 05, 2020

Pubmed Data : Food Chem Toxicol. 2020 Jul 6:111540. Epub 2020 Jul 6. PMID: 32645469
Article Published Date : Jul 05, 2020
Study Type : Animal Study
Additional Links
Substances : Probiotics
Diseases : Bisphenol Toxicity, Phthalate Toxicity
Pharmacological Actions : Gastrointestinal Agents, Hepatoprotective, Renoprotective
Problem Substances : Bisphenol A , Phthalates
[+]

Neuro-protective potentials of N-acetylcysteine and zinc against phthalate-induced neuro-histopathology and dys-regulations of dopamine and glutamate.Dec 31, 2022

Pubmed Data : J Environ Sci Health A Tox Hazard Subst Environ Eng. 2023 ;58(1):81-90. Epub 2023 Feb 28. PMID: 36852734
Article Published Date : Dec 31, 2022
Study Type : Animal Study
Additional Links
Substances : NAC (N-acetyl-L-cysteine), Zinc
Diseases : Phthalate Toxicity
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Phthalates
[+]

Parental exposure to polystyrene nanoplastics and di(2-ethylhexyl) phthalate induces transgenerational growth and reproductive impairments.Jul 14, 2023

Pubmed Data : Sci Total Environ. 2023 Jul 15 ;882:163657. Epub 2023 Apr 19. PMID: 37084918
Article Published Date : Jul 14, 2023
Study Type : Insect Study
Additional Links
Diseases : Infertility, Microplastic Toxicity
Additional Keywords : Transgenerational inheritance
Problem Substances : Phthalates, Polystyrene nanoparticles
[+]

Persistent immunosuppressive effects of dibutyl phthalate exposure.Jun 19, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Total Environ. 2023 Jun 20 ;878:162741. Epub 2023 Mar 11. PMID: 36914131
Article Published Date : Jun 19, 2023
Study Type : Animal Study
Additional Links
Diseases : Phthalate Toxicity
Problem Substances : Phthalates
Adverse Pharmacological Actions : Immunosuppressive
[+]

Phthalate esters with long-term low-dose exposure may pose male reproductive toxicity in humans.Feb 28, 2017

Pubmed Data : Food Chem Toxicol. 2017 Mar ;101:94-104. Epub 2017 Jan 12. PMID: 28089693
Article Published Date : Feb 28, 2017
Study Type : Animal Study
Additional Links
Diseases : Infertility: Male, Phthalate Toxicity
Problem Substances : Phthalates
Adverse Pharmacological Actions : Teratogenic
[+]

Phthalate may interfere with testicular function and disrupt androgen action. Apr 01, 2009

Pubmed Data : Trends Endocrinol Metab. 2009 Apr;20(3):139-45. Epub 2009 Mar 9. PMID: 19278865
Article Published Date : Apr 01, 2009
Study Type : Animal Study
Additional Links
Diseases : Testicular Diseases, Testicular Dysgenesis
Problem Substances : Phthalates
[+]

Phthalates alter fetal steroid hormones and genes. Sep 01, 2007

Pubmed Data : Toxicol Sci. 2007 Sep;99(1):190-202. Epub 2007 Mar 30. PMID: 17400582
Article Published Date : Sep 01, 2007
Study Type : Animal Study
Additional Links
Diseases : Prenatal Chemical Exposures
Problem Substances : Phthalates
[+]

Phthalates exposure may be related to statistically significant ALT and AST serum levels increment as well as with increased BMI.Dec 12, 2017

Pubmed Data : Environ Monit Assess. 2017 Dec 13 ;190(1):17. Epub 2017 Dec 13. PMID: 29234897
Article Published Date : Dec 12, 2017
Study Type : Animal Study
Additional Links
Diseases : Obesity, Respiratory Diseases
Problem Substances : Phthalates
[+]

Phthalates inhibit fetal testicular testosterone production in the rat in a cumulative, dose-additive manner.Sep 01, 2008

Pubmed Data : Toxicol Sci. 2008 Sep;105(1):153-65. Epub 2008 Apr 14. PMID: 18411233
Article Published Date : Sep 01, 2008
Study Type : Animal Study
Additional Links
Diseases : Prenatal Chemical Exposures, Testosterone: Too Low
Problem Substances : Phthalates
[+]

Phthalates may disrupt heart rate variability and cardiovascular reactivity.Aug 24, 2017

Pubmed Data : Am J Physiol Heart Circ Physiol. 2017 Aug 25:ajpheart.00364.2017. Epub 2017 Aug 25. PMID: 28842438
Article Published Date : Aug 24, 2017
Study Type : Animal Study
Additional Links
Diseases : Phthalate Toxicity
Problem Substances : Phthalates
Adverse Pharmacological Actions : Cardiotoxic
[+]

Phthlate exposure may inhibit sperm production and/or quality. Mar 01, 2007

Pubmed Data : Asian J Androl. 2007 Mar;9(2):199-205. Epub 2006 Jul 11. PMID: 16855774
Article Published Date : Mar 01, 2007
Study Type : Animal Study
Additional Links
Diseases : Infertility: Male, Sperm Count: Low, Sperm Quality: Low, Testicular Diseases
Problem Substances : Phthalates
[+]

Polystyrene nanoparticles aggravate the adverse effects of di-(2-ethylhexyl) phthalate on different segments of intestine.Sep 30, 2022

Pubmed Data : Chemosphere. 2022 Oct ;305:135324. Epub 2022 Jun 11. PMID: 35697104
Article Published Date : Sep 30, 2022
Study Type : Animal Study
Additional Links
Diseases : Microplastic Toxicity, Phthalate Toxicity
Additional Keywords : Synergistic Toxicity
Problem Substances : Phthalates, Polystyrene nanoparticles
[+]

Polystyrene nanoparticles enhance the adverse effects of di-(2-ethylhexyl) phthalate on male reproductive system in mice.Oct 14, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ecotoxicol Environ Saf. 2022 Oct 15 ;245:114104. Epub 2022 Sep 26. PMID: 36174316
Article Published Date : Oct 14, 2022
Study Type : Animal Study
Additional Links
Diseases : Infertility: Male, Microplastic Toxicity, Phthalate Toxicity
Problem Substances : Phthalates, Polystyrene nanoparticles
[+]

Polystyrene nanoplastics aggravated dibutyl phthalate-induced blood-testis barrier dysfunction.Sep 30, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ecotoxicol Environ Saf. 2023 Oct 1 ;264:115403. Epub 2023 Aug 31. PMID: 37659273
Article Published Date : Sep 30, 2023
Study Type : Animal Study
Additional Links
Diseases : Microplastic Toxicity, Phthalate Toxicity, Testicular Injury: Chemical/Metal Induced
Problem Substances : Phthalates, Polystyrene nanoparticles
[+]

Prenatal exposure to a phthalate mixture leads to multigenerational and transgenerational effects on uterine morphology and function in mice.Feb 28, 2020

Pubmed Data : Reprod Toxicol. 2020 Feb 29. Epub 2020 Feb 29. PMID: 32126281
Article Published Date : Feb 28, 2020
Study Type : Animal Study
Additional Links
Diseases : Phthalate Toxicity, Prenatal Chemical Exposures
Additional Keywords : Transgenerational inheritance
Problem Substances : Phthalates
[+]

Prenatal exposure to bisphenol A and/or diethylhexyl phthalate alters stress responses in rat offspring.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Toxicol. 2023 ;5:1264238. Epub 2023 Dec 13. PMID: 38152552
Article Published Date : Dec 31, 2022
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity, Phthalate Toxicity, Prenatal Chemical Exposures
Additional Keywords : Synergistic Toxicity, Transgenerational inheritance
Problem Substances : Bisphenol A , Phthalates
[+]

Prenatal exposures to bisphenol A and di (2-ethylhexyl) phthalate disrupted seminiferous tubular development in growing male rats.Jul 28, 2019

Pubmed Data : Reprod Toxicol. 2019 Jul 29. Epub 2019 Jul 29. PMID: 31369804
Article Published Date : Jul 28, 2019
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity, Male Reproductive Development Abnormalities, Prenatal Chemical Exposures
Problem Substances : Bisphenol A , Phthalates
[+]

Probiotic reduced the impact of phthalates and bisphenol A mixture on type 2 diabetes mellitus development.Jun 04, 2021

Pubmed Data : Food Chem Toxicol. 2021 Jun 5 ;154:112325. Epub 2021 Jun 5. PMID: 34097988
Article Published Date : Jun 04, 2021
Study Type : Animal Study
Additional Links
Substances : Probiotics
Diseases : Bisphenol Toxicity, Diabetes Mellitus: Type 2
Pharmacological Actions : Antioxidants, Pancreato Protective Agents
Problem Substances : Bisphenol A , Phthalates
[+]

Protective effect of alpha-lipoic acid on di-(2-ethylhexyl) phthalate-induced testicular toxicity in mice.Feb 06, 2020

Pubmed Data : Environ Sci Pollut Res Int. 2020 Feb 7. Epub 2020 Feb 7. PMID: 32030592
Article Published Date : Feb 06, 2020
Study Type : Animal Study
Additional Links
Substances : Alpha-Lipoic Acid
Diseases : Phthalate Toxicity, Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Antioxidants
Problem Substances : Phthalates
[+]

Protective effect of Lycium barbarum polysaccharide on di-(2-ethylhexyl) phthalate-induced toxicity in rat liver.Jan 14, 2021

Pubmed Data : Environ Sci Pollut Res Int. 2021 Jan 15. Epub 2021 Jan 15. PMID: 33449321
Article Published Date : Jan 14, 2021
Study Type : Animal Study
Additional Links
Substances : Goji
Diseases : Phthalate Toxicity
Additional Keywords : Polysaccharides
Problem Substances : Phthalates
[+]

Quercetin has a potent protective effect against DEHP-induced testicular toxicity in rats.Apr 14, 2015

Pubmed Data : Hum Exp Toxicol. 2015 Apr 15. Epub 2015 Apr 15. PMID: 25882133
Article Published Date : Apr 14, 2015
Study Type : Animal Study
Additional Links
Substances : Quercetin
Diseases : Oxidative Stress, Phthalate Toxicity
Pharmacological Actions : Antioxidants
Problem Substances : Phthalates
[+]

Recovery from a myocardial infarction is impaired by exposure to bisphenols and phthalates that escape from medical devices used in cardiac surgery.Nov 05, 2018

Pubmed Data : Toxicol Sci. 2018 Nov 6. Epub 2018 Nov 6. PMID: 30398665
Article Published Date : Nov 05, 2018
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity, Cardiac Surgery
Additional Keywords : Risk Factors
Problem Substances : Bisphenol A , Phthalates
[+]

Role of mitochondria-endoplasmic reticulum coupling in lycopene preventing DEHP-induced hepatotoxicity.Oct 04, 2021

Pubmed Data : Food Funct. 2021 Oct 5. Epub 2021 Oct 5. PMID: 34608470
Article Published Date : Oct 04, 2021
Study Type : Animal Study
Additional Links
Substances : Lycopene
Diseases : Chemically-Induced Liver Damage, Phthalate Toxicity
Pharmacological Actions : Hepatoprotective
Problem Substances : Phthalates
[+]

Rutin prevents cardiac oxidative stress and inflammation induced by bisphenol A and dibutyl phthalate exposure.Aug 08, 2021

Pubmed Data : Life Sci. 2021 Aug 9:119878. Epub 2021 Aug 9. PMID: 34384828
Article Published Date : Aug 08, 2021
Study Type : Animal Study
Additional Links
Substances : Rutin
Diseases : Bisphenol Toxicity, Phthalate Toxicity
Pharmacological Actions : Antioxidants, Cardioprotective, Nrf2 activation
Problem Substances : Bisphenol A , Phthalates
[+]

Suburban plastic film greenhouses led to an increase in phthalate esters in soils and more so in the vegetables, with average concentrations of 3.00mg/kg.Apr 06, 2015

Pubmed Data : Sci Total Environ. 2015 Apr 7 ;523:129-137. Epub 2015 Apr 7. PMID: 25863503
Article Published Date : Apr 06, 2015
Study Type : Environmental
Additional Links
Additional Keywords : Plastic Greenhouse, Risk Factors
Problem Substances : Phthalates
[+]

Summertime temperatures inside of cars, garages, and enclosed storage areas can exceed 65 degrees C and thus could promote antimony leaching from PET bottled waters.Jan 31, 2008

Pubmed Data : Water Res. 2008 Feb ;42(3):551-6. Epub 2007 Aug 6. PMID: 17707454
Article Published Date : Jan 31, 2008
Study Type : Environmental
Additional Links
Additional Keywords : Bottled Water
Problem Substances : Antimony, Phthalates, Polyethylene terephthalate (PET)
[+]

Taxifolin alleviates apoptotic injury induced by DEHP exposure through cytochrome P450 homeostasis in chicken cardiomyocytes.Nov 14, 2019

Pubmed Data : Ecotoxicol Environ Saf. 2019 Nov 15 ;183:109582. Epub 2019 Aug 20. PMID: 31442803
Article Published Date : Nov 14, 2019
Study Type : Animal Study
Additional Links
Substances : Flavonoids
Diseases : Oxidative Stress, Phthalate Toxicity
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Cardioprotective
Problem Substances : Phthalates
[+]

Taxifolin ameliorates DEHP-induced cardiomyocyte hypertrophy.Nov 30, 2019

Pubmed Data : Environ Pollut. 2019 Dec ;255(Pt 1):113155. Epub 2019 Sep 11. PMID: 31539850
Article Published Date : Nov 30, 2019
Study Type : Animal Study
Additional Links
Substances : Flavonoids
Diseases : Cardiomegaly, Phthalate Toxicity
Pharmacological Actions : Cardioprotective
Problem Substances : Phthalates
[+]

Taxifolin attenuates the developmental testicular toxicity induced by di-n-butyl phthalate in fetal male rats.Jul 31, 2020

Pubmed Data : Food Chem Toxicol. 2020 Aug ;142:111482. Epub 2020 Jun 7. PMID: 32525071
Article Published Date : Jul 31, 2020
Study Type : Animal Study
Additional Links
Substances : Flavonoids
Diseases : Phthalate Toxicity, Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Antioxidants
Problem Substances : Phthalates
[+]

The ameliorative effect of ellagic acid on di-(2-ethylhexyl) phthalate-induced testicular structural alterations.Sep 17, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Reprod Biol Endocrinol. 2021 Sep 18 ;19(1):146. Epub 2021 Sep 18. PMID: 34537068
Article Published Date : Sep 17, 2021
Study Type : Animal Study
Additional Links
Substances : Ellagic Acid
Diseases : Phthalate Toxicity, Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
Problem Substances : Phthalates
[+]

The complex action of DEHP/BPA mixture may disturb the thyroid hormone homeostasis.Oct 31, 2020

Pubmed Data : Environ Sci Pollut Res Int. 2020 Nov ;27(32):40882-40892. Epub 2020 Jul 17. PMID: 32681327
Article Published Date : Oct 31, 2020
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity, Phthalate Toxicity, Thyroid Dysfunction
Additional Keywords : Risk Factors
Problem Substances : Bisphenol A , Phthalates
[+]

The effect of apigenin, an aryl hydrocarbon receptor antagonist, in Phthalate-Exacerbated eosinophilic asthma model.Jun 30, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cell Mol Med. 2023 Jul ;27(13):1900-1910. Epub 2023 Jun 14. PMID: 37315181
Article Published Date : Jun 30, 2023
Study Type : Animal Study
Additional Links
Substances : Apigenin
Diseases : Asthma, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents
Problem Substances : Phthalates
[+]

The protective effects of thymol and carvacrol against di (2-ethylhexyl) phthalate-induced cytotoxicity in HEK-293 cells.May 05, 2022

Pubmed Data : J Biochem Mol Toxicol. 2022 May 6:e23092. Epub 2022 May 6. PMID: 35521929
Article Published Date : May 05, 2022
Study Type : Animal Study
Additional Links
Substances : Carvacrol, Thymol
Diseases : Kidney Damage: Chemically-Induced, Phthalate Toxicity
Pharmacological Actions : Antioxidants, Renoprotective
Problem Substances : Phthalates
[+]

The results also showed that the presence of glycerin monostearate exacerbated the toxicities of MIXPs to male rat reproductive system.Feb 14, 2018

Pubmed Data : Toxicol Appl Pharmacol. 2018 Feb 15 ;341:87-97. Epub 2018 Feb 3. PMID: 29366639
Article Published Date : Feb 14, 2018
Study Type : Animal Study
Additional Links
Diseases : Infertility: Male
Problem Substances : Phthalates
[+]

Therapeutic efficacy of N-acetylcysteine and zinc sulphate against di-(2-ethylhexyl) phthalate-induced testicular oxido-nitrergic stress.Sep 30, 2022

Pubmed Data : Andrologia. 2022 Oct ;54(9):e14508. Epub 2022 Jul 17. PMID: 35842931
Article Published Date : Sep 30, 2022
Study Type : Animal Study
Additional Links
Substances : NAC (N-acetyl-L-cysteine), Zinc
Diseases : Phthalate Toxicity, Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Antioxidants
Problem Substances : Phthalates
[+]

Toxic effects of the mixture of phthalates and bisphenol A-subacute oral toxicity study in rats.Jan 22, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Environ Res Public Health. 2020 Jan 23 ;17(3). Epub 2020 Jan 23. PMID: 31979393
Article Published Date : Jan 22, 2020
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity, Phthalate Toxicity
Additional Keywords : Increased Risk
Problem Substances : Bisphenol A , Phthalates
[+]

Vanillic acid and Vitamin C supplementation attenuated the toxic effects of DEHP on the testicular functions.Jul 31, 2022

Pubmed Data : Reprod Fertil. 2022 Aug 1. Epub 2022 Aug 1. PMID: 35980228
Article Published Date : Jul 31, 2022
Study Type : Animal Study
Additional Links
Substances : Vitamin C
Diseases : Phthalate Toxicity, Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Antioxidants
Problem Substances : Phthalates
[+]

Vitamin C mitigates hematological and biochemical alterations caused by di(2-ethylhexyl) phthalate toxicity.Oct 06, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Comp Clin Path. 2022 Oct 7:1-12. Epub 2022 Oct 7. PMID: 36247333
Article Published Date : Oct 06, 2022
Study Type : Animal Study
Additional Links
Substances : Vitamin C
Diseases : Phthalate Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Malondialdehyde Down-regulation
Problem Substances : Phthalates
[+]

Vitamin E and curcumin can alleviate dibutyl phthalate-induced splenic injury.Nov 07, 2019

Pubmed Data : Food Chem Toxicol. 2019 Nov 8:110955. Epub 2019 Nov 8. PMID: 31712109
Article Published Date : Nov 07, 2019
Study Type : Animal Study
Additional Links
Substances : Curcumin, Vitamin E
Diseases : Oxidative Stress, Phthalate Toxicity
Pharmacological Actions : Immunomodulatory
Problem Substances : Phthalates
[+]

Bisphenols and phthalates: Plastic chemical exposures can contribute to adverse cardiovascular health outcomes.Jul 20, 2020

Pubmed Data : Birth Defects Res. 2020 Jul 21. Epub 2020 Jul 21. PMID: 32691967
Article Published Date : Jul 20, 2020
Study Type : Review
Additional Links
Diseases : Bisphenol Toxicity, Phthalate Toxicity
Problem Substances : Bisphenol A , Phthalates
Adverse Pharmacological Actions : Cardiotoxic
[+]

Didymin reverses phthalate ester-associated breast cancer aggravation in the breast cancer tumor microenvironment.Jan 31, 2016

Pubmed Data : Oncol Lett. 2016 Feb ;11(2):1035-1042. Epub 2015 Dec 7. PMID: 26893687
Article Published Date : Jan 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids
Diseases : Breast Cancer, Phthalate Toxicity
Pharmacological Actions : Anti-metastatic, Antiproliferative
Additional Keywords : Tumor Microenvironment
Problem Substances : Phthalates
[+]

Exposure to phthalates from polyvinyl chloride products may contribute to the development of asthma and allergiesJul 01, 2008

Pubmed Data : Environ Health Perspect. 2008 Jul;116(7):845-53. PMID: 18629304
Article Published Date : Jul 01, 2008
Study Type : Review
Additional Links
Diseases : Allergies, Asthma
Problem Substances : Phthalates
[+]

A review of developmental neurotoxicants and the vulnerable male brain.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Acta Neurobiol Exp (Wars). 2017 ;77(4):269-296. PMID: 29369294
Article Published Date : Dec 31, 2016
Study Type : Review
Additional Links
Problem Substances : Bisphenol A , Organochlorine pesticides, Phthalates, Thimerosal
[+]

A review of the exposure to environmental chemicals and type 1 diabetes.Mar 11, 2019

Pubmed Data : J Epidemiol Community Health. 2019 Mar 12. Epub 2019 Mar 12. PMID: 30862699
Article Published Date : Mar 11, 2019
Study Type : Review
Additional Links
Diseases : Diabetes Mellitus: Type 1
Additional Keywords : Risk Factors
Problem Substances : Bisphenol A , Persistent organic pollutants (POPs), Pesticides, Phthalates
[+]

A review of the relationship between phthalates and diabetes.Jun 10, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Metabolites. 2023 Jun 11 ;13(6). Epub 2023 Jun 11. PMID: 37367903
Article Published Date : Jun 10, 2023
Study Type : Review
Additional Links
Diseases : Diabetes Mellitus: Type 1, Diabetes Mellitus: Type 2
Additional Keywords : Risk Factors
Problem Substances : Phthalates
[+]

Antimony exposure may occur from the use of polyethylene terephthalate (PET) traysAug 01, 2007

Pubmed Data : Food Addit Contam. 2007 Aug;24(8):860-8. PMID: 17613073
Article Published Date : Aug 01, 2007
Study Type : Commentary
Additional Links
Problem Substances : Antimony, Phthalates, Polyethylene terephthalate (PET)
[+]

Association between phthalate exposure and obesity risk.Aug 04, 2023

Pubmed Data : Environ Toxicol Pharmacol. 2023 Aug 5 ;102:104240. Epub 2023 Aug 5. PMID: 37549759
Article Published Date : Aug 04, 2023
Study Type : Review
Additional Links
Diseases : Obesity, Phthalate Toxicity
Additional Keywords : Risk Factors
Problem Substances : Phthalates
[+]

Autism genes are selectively targeted by environmental pollutants.Oct 26, 2016

Pubmed Data : Neurochem Int. 2016 Oct 27. Epub 2016 Oct 27. PMID: 27984170
Article Published Date : Oct 26, 2016
Study Type : Review
Additional Links
Diseases : Autism
Additional Keywords : Gene Expression
Problem Substances : Acetaminophen, Benzo(a)pyrene, Bisphenol A , Heavy Metals, Pesticides, Phthalates
[+]

Benzyl butyl phthalate exposure may disturb neural tube development by strengthening oxidative stress.May 31, 2020

Pubmed Data : Toxicol Res (Camb). 2020 Jun ;9(3):222-229. Epub 2020 May 8. PMID: 32670553
Article Published Date : May 31, 2020
Study Type : In Vitro Study
Additional Links
Diseases : Oxidative Stress, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Benzyl butyl phthalate influences the efficacy of chemotherapy by remodelling the tumor microenvironment of breast cancer.Nov 30, 2015

Pubmed Data : Oncol Rep. 2015 Dec ;34(6):2889-900. Epub 2015 Sep 23. PMID: 26397389
Article Published Date : Nov 30, 2015
Study Type : In Vitro Study
Additional Links
Diseases : Breast Cancer, Cancers: Drug Resistant
Additional Keywords : Chemoresistance, Tumor Microenvironment
Problem Substances : Phthalates
[+]

Bisphenol A and dibutyl phthalate affect the expression of juxtacrine signaling factors in rat testis.Feb 04, 2018

Pubmed Data : Chemosphere. 2018 Feb 5 ;199:182-190. Epub 2018 Feb 5. PMID: 29438945
Article Published Date : Feb 04, 2018
Study Type : In Vitro Study
Additional Links
Diseases : Bisphenol Toxicity, Testicular Injury: Chemical/Metal Induced
Problem Substances : Bisphenol A , Phthalates
[+]

Bisphenol A and dibutyl phthalate affect the expression of juxtacrine signaling factors in rat testis.Feb 04, 2018

Pubmed Data : Chemosphere. 2018 Feb 5 ;199:182-190. Epub 2018 Feb 5. PMID: 29438945
Article Published Date : Feb 04, 2018
Study Type : In Vitro Study
Additional Links
Diseases : Bisphenol Toxicity, Testicular Injury: Chemical/Metal Induced
Problem Substances : Bisphenol A , Phthalates
[+]

Bisphenol A drives di(2-ethylhexyl) phthalate promoting thyroid tumorigenesis.Jan 04, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Hazard Mater. 2022 03 5 ;425:127911. Epub 2021 Nov 26. PMID: 34910997
Article Published Date : Jan 04, 2022
Study Type : In Vitro Study
Additional Links
Diseases : Bisphenol Toxicity, Phthalate Toxicity, Thyroid Cancer
Problem Substances : Bisphenol A , Phthalates
[+]

Bisphenol A is more potent than phthalate metabolites in reducing pancreatic β-cell function.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2017 ;2017:4614379. Epub 2017 Feb 13. PMID: 28286763
Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Diseases : Bisphenol Toxicity, Insulin Resistance
Problem Substances : Bisphenol A , Phthalates
[+]

Combined cytotoxicity of polystyrene nanoplastics and phthalate esters on human lung epithelial A549 cells and its mechanism.Apr 14, 2021

Pubmed Data : Ecotoxicol Environ Saf. 2021 Apr 15 ;213:112041. Epub 2021 Feb 15. PMID: 33601174
Article Published Date : Apr 14, 2021
Study Type : In Vitro Study
Additional Links
Diseases : Inflammation, Microplastic Toxicity, Oxidative Stress, Phthalate Toxicity
Additional Keywords : Synergistic Toxicity
Problem Substances : Phthalates, Polystyrene nanoparticles
[+]

Combined exposure to di(2-ethylhexyl) phthalate and polystyrene microplastics induced renal autophagy.Dec 31, 2022

Pubmed Data : Food Chem Toxicol. 2023 Jan ;171:113521. Epub 2022 Nov 21. PMID: 36423728
Article Published Date : Dec 31, 2022
Study Type : In Vitro Study
Additional Links
Diseases : Microplastic Toxicity, Phthalate Toxicity
Additional Keywords : Synergistic Toxicity
Problem Substances : Phthalates
[+]

Cotton and fashion masks increase human exposure to microplastics and phthalates both indoors and outdoors.Jan 16, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Toxics. 2023 Jan 17 ;11(2). Epub 2023 Jan 17. PMID: 36850963
Article Published Date : Jan 16, 2023
Study Type : In Vitro Study
Additional Links
Diseases : Face Mask Harms/Ineffectiveness, Phthalate Toxicity
Additional Keywords : Microplastic
Problem Substances : Phthalates
[+]

Curcumin may be a potential treatment for preventing the harmful effects of phthalates.Aug 14, 2017

Pubmed Data : Toxicol Appl Pharmacol. 2017 Aug 15 ;329:158-164. PMID: 28595985
Article Published Date : Aug 14, 2017
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Phthalate Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Phthalates
[+]

Diethylhexyl phthalate and bisphenol A promote vincristine and tamoxifen resistance.Mar 20, 2022

Pubmed Data : Chem Res Toxicol. 2022 Mar 21 ;35(3):538-546. Epub 2022 Mar 9. PMID: 35263089
Article Published Date : Mar 20, 2022
Study Type : In Vitro Study
Additional Links
Diseases : Bisphenol Toxicity, Cancers: Drug Resistant
Additional Keywords : Increased Risk
Problem Substances : Bisphenol A , Phthalates
[+]

Diethylhexyl phthalate can increase proliferation while decrease chemosensitivity of esophageal squamous cell carcinoma cells.Mar 14, 2021

Pubmed Data : Hum Cell. 2021 Mar 15. Epub 2021 Mar 15. PMID: 33721218
Article Published Date : Mar 14, 2021
Study Type : In Vitro Study
Additional Links
Diseases : Esophageal Cancer, Phthalate Toxicity
Additional Keywords : Increased Risk
Problem Substances : Phthalates
[+]

Early-life exposure to EDCs: role in childhood obesity and neurodevelopment.Nov 17, 2016

Pubmed Data : Nat Rev Endocrinol. 2016 Nov 18. Epub 2016 Nov 18. PMID: 27857130
Article Published Date : Nov 17, 2016
Study Type : Review
Additional Links
Diseases : Neurodevelopmental Disorders, Obesity
Additional Keywords : Risk Factors
Problem Substances : Bisphenol A , Endocrine Disrupting Chemicals (EDCs), Phthalates, Triclosan
[+]

Effects of individual and combined toxicity of bisphenol A, dibutyl phthalate and cadmium on oxidative stress and genotoxicity in HepG 2 cells.Mar 27, 2017

Pubmed Data : Food Chem Toxicol. 2017 Mar 28 ;105:73-81. Epub 2017 Mar 28. PMID: 28363854
Article Published Date : Mar 27, 2017
Study Type : In Vitro Study
Additional Links
Diseases : Bisphenol Toxicity, Oxidative Stress
Additional Keywords : Synergistic Toxicity
Problem Substances : Bisphenol A , Cadmium, Endocrine Disruptors, Phthalates
[+]

Emerging science indicates that deleterious immunologic changes, including increased propensity to develop wheeze, allergy, and asthma after dietary and inhalation exposure to these chemicals.Sep 03, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Curr Environ Health Rep. 2015 Sep 4. Epub 2015 Sep 4. PMID: 26337065
Article Published Date : Sep 03, 2015
Study Type : Review
Additional Links
Diseases : Allergies, Asthma, Bisphenol-A Toxicity, Phthalate Toxicity
Problem Substances : Bisphenol A , Phthalates
[+]

Endocrine disrupting chemicals and type 1 diabetes. Apr 21, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2020 Apr 22 ;21(8). Epub 2020 Apr 22. PMID: 32331412
Article Published Date : Apr 21, 2020
Study Type : Review
Additional Links
Diseases : Diabetes Mellitus: Type 1
Additional Keywords : Risk Factors
Problem Substances : Bisphenol A , Endocrine Disrupting Chemicals (EDCs), Phthalates, Polychlorinated biphenyls (PCBs)
[+]

Endocrine disrupting chemicals can increase the risk aggravating the disease for the patients suffering cancer.Dec 28, 2016

Pubmed Data : Mol Cell Endocrinol. 2016 Dec 29. Epub 2016 Dec 29. PMID: 28042023
Article Published Date : Dec 28, 2016
Study Type : In Vitro Study
Additional Links
Diseases : Bisphenol Toxicity, Cancer Metastasis, Cancers: All
Additional Keywords : Risk Factors
Problem Substances : 8-tetrachlorodibenzo-p-dioxin (TCDD), Bisphenol A , Phthalates, Triclosan
[+]

Endocrine-disrupting chemicals may effect proliferation and metastasis of cancer cells and tumor progression.Dec 31, 2015

Pubmed Data : J Environ Pathol Toxicol Oncol. 2016 ;35(1):43-58. PMID: 27279583
Article Published Date : Dec 31, 2015
Study Type : Review
Additional Links
Diseases : Breast Cancer, Cancer Metastasis, Cancers: All, Ovarian Cancer
Problem Substances : Bisphenol A , Endocrine Disrupting Chemicals (EDCs), Phthalates
[+]

Estimation of exposure to phthalate esters from consumption of powdered infant formula sampled in Turkey.May 31, 2023

Pubmed Data : Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2023 Jun ;40(6):745-756. Epub 2023 May 22. PMID: 37216587
Article Published Date : May 31, 2023
Study Type : In Vitro Study
Additional Links
Diseases : Phthalate Toxicity
Problem Substances : Infant Formula, Phthalates
[+]

Even at a very low concentration phthalates was capable of inducing proliferative effects on breast cancer cells.Nov 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Taiwan J Obstet Gynecol. 2016 Dec ;55(6):826-834. PMID: 28040128
Article Published Date : Nov 30, 2016
Study Type : In Vitro Study
Additional Links
Diseases : Breast Cancer, Phthalate Toxicity
Additional Keywords : Risk Factors
Problem Substances : Phthalates
[+]

Evidence is accumulating that endocrine-disrupting chemicals might be involved in diabetes development.May 08, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Diabetologia. 2018 May 9. Epub 2018 May 9. PMID: 29744538
Article Published Date : May 08, 2018
Study Type : Review
Additional Links
Diseases : Bisphenol Toxicity, Diabetes Mellitus: Type 2
Problem Substances : Bisphenol A , Phthalates
[+]

Exposure to phthalates from personal care products: Urinary levels and predictors of exposure.Mar 27, 2022

Pubmed Data : Environ Res. 2022 Mar 28:113194. Epub 2022 Mar 28. PMID: 35358548
Article Published Date : Mar 27, 2022
Study Type : Review
Additional Links
Diseases : Phthalate Toxicity
Problem Substances : Phthalates
[+]

Feminine hygiene products are a neglected source of phthalate exposure in women.Dec 19, 2019

Pubmed Data : Environ Sci Technol. 2019 Dec 20. Epub 2019 Dec 20. PMID: 31859481
Article Published Date : Dec 19, 2019
Study Type : In Vitro Study
Additional Links
Diseases : Phthalate Toxicity
Additional Keywords : Risk Factors
Problem Substances : Phthalates
[+]

Hericium Erinaceus prevents DEHP-induced mitochondrial dysfunction and apoptosis in PC12 cells.Mar 19, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2020 Mar 20 ;21(6). Epub 2020 Mar 20. PMID: 32244920
Article Published Date : Mar 19, 2020
Study Type : In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Phthalate Toxicity
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Neuroprotective Agents, Nrf2 activation
Problem Substances : Phthalates
[+]

Impacts of bisphenol A and phthalate exposures on epigenetic outcomes in the human placenta.Jun 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Epigenet. 2018 Jul ;4(3):dvy022. Epub 2018 Sep 7. PMID: 30210810
Article Published Date : Jun 30, 2018
Study Type : Review
Additional Links
Diseases : Bisphenol Toxicity
Problem Substances : Bisphenol A , Phthalates
[+]

Lycopene prevents DEHP-induced hepatic oxidative stress damage by crosstalk between AHR-Nrf2 pathway.Sep 14, 2021

Pubmed Data : Environ Pollut. 2021 Sep 15 ;285:117080. Epub 2021 Apr 7. PMID: 33965855
Article Published Date : Sep 14, 2021
Study Type : In Vitro Study
Additional Links
Substances : Lycopene
Diseases : Oxidative Stress, Phthalate Toxicity
Pharmacological Actions : Antioxidants
Problem Substances : Phthalates
[+]

Mechanisms of testicular disruption from exposure to bisphenol A and phtalates.Feb 07, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Clin Med. 2020 Feb 8 ;9(2). Epub 2020 Feb 8. PMID: 32046352
Article Published Date : Feb 07, 2020
Study Type : Review
Additional Links
Diseases : Bisphenol Toxicity, Phthalate Toxicity, Testicular Injury: Chemical/Metal Induced
Problem Substances : Bisphenol A , Phthalates
[+]

Microplastics and phthalate esters release from teabags into tea drink.Sep 30, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Sci Pollut Res Int. 2023 Oct ;30(47):104209-104222. Epub 2023 Sep 12. PMID: 37697202
Article Published Date : Sep 30, 2023
Study Type : In Vitro Study
Additional Links
Substances : Black Tea, Green Tea
Diseases : Microplastic Toxicity, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Migration of phthalates from PET water bottle in events of repeated uses and associated risk assessment.Jul 07, 2020

Pubmed Data : Environ Sci Pollut Res Int. 2020 Jul 8. Epub 2020 Jul 8. PMID: 32642892
Article Published Date : Jul 07, 2020
Study Type : In Vitro Study
Additional Links
Diseases : Phthalate Toxicity
Additional Keywords : Bottled Water, Plastic Bottle
Problem Substances : Phthalates
[+]

Occurrence of phthalate esters in over-the-counter medicines from China and its implications for human exposure.Nov 02, 2016

Pubmed Data : Environ Int. 2016 Nov 3. Epub 2016 Aug 3. PMID: 27817868
Article Published Date : Nov 02, 2016
Study Type : In Vitro Study
Additional Links
Diseases : Phthalate Toxicity
Additional Keywords : Risk Factors
Problem Substances : Phthalates
[+]

Phthalate esters and their potential risk in PET bottled water stored under common conditions.Jan 23, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Environ Res Public Health. 2019 12 24 ;17(1). Epub 2019 Dec 24. PMID: 31878152
Article Published Date : Jan 23, 2019
Study Type : In Vitro Study
Additional Links
Diseases : Phthalate Toxicity
Additional Keywords : Bottled Water, Plastic Bottle
Problem Substances : Phthalates
[+]

Phthalate exposure from several pharmaceutical products exceeded the regulatory exposure limit introduced in 2014.Mar 28, 2017

Pubmed Data : Basic Clin Pharmacol Toxicol. 2017 Mar 29. Epub 2017 Mar 29. PMID: 28371296
Article Published Date : Mar 28, 2017
Study Type : In Vitro Study
Additional Links
Diseases : Phthalate Toxicity
Additional Keywords : Pharmaceutical Contaminants
Problem Substances : Phthalates
[+]

Phthalate plasticizer di(2-ethyl-hexyl) phthalate induces cyclooxygenase-2 expression in gastric adenocarcinoma cells.Jul 15, 2019

Pubmed Data : Environ Toxicol. 2019 Jul 16. Epub 2019 Jul 16. PMID: 31313480
Article Published Date : Jul 15, 2019
Study Type : In Vitro Study
Additional Links
Diseases : Gastric Cancer, Inflammation, Phthalate Toxicity
Additional Keywords : Risk Factors
Problem Substances : Phthalates
[+]

Phthalate-induced fetal leydig cell dysfunction mediates male reproductive tract anomalies.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2019 ;10:1309. Epub 2019 Nov 6. PMID: 31780936
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Diseases : Male Reproductive Development Abnormalities, Phthalate Toxicity, Prenatal Chemical Exposures
Problem Substances : Phthalates
[+]

Phthalates adversely affect reproductive outcomes and children's health. Jun 01, 2011

Pubmed Data : Int J Occup Med Environ Health. 2011 Jun ;24(2):115-41. Epub 2011 May 19. PMID: 21594692
Article Published Date : Jun 01, 2011
Study Type : Review
Additional Links
Diseases : Gynecomastia, Premature Puberty, Premature Thelarche
Problem Substances : Phthalates
Adverse Pharmacological Actions : Endocrine Disruptor
[+]

Phthalates contribute to testicular dysgenesis. Mar 01, 2007

Pubmed Data : Zhonghua Nan Ke Xue. 2007 Mar;13(3):195-200. PMID: 17393778
Article Published Date : Mar 01, 2007
Study Type : Commentary
Additional Links
Diseases : Testicular Dysgenesis, Testosterone: Too Low
Problem Substances : Phthalates
[+]

Preliminary evaluation of plasticizer and BPA in Tunisian cosmetics and investigation of hazards on human skin cells.Sep 30, 2018

Pubmed Data : Int J Environ Health Res. 2018 Oct ;28(5):491-501. Epub 2018 Jul 16. PMID: 30010399
Article Published Date : Sep 30, 2018
Study Type : In Vitro Study
Additional Links
Diseases : Bisphenol Toxicity
Problem Substances : Bisphenol A , Phthalates
[+]

Promising hepatoprotective effects of lycopene in different liver diseases.Nov 30, 2022

Pubmed Data : Life Sci. 2022 Dec 1 ;310:121131. Epub 2022 Oct 25. PMID: 36306869
Article Published Date : Nov 30, 2022
Study Type : Review
Additional Links
Substances : Carotenoids, Lycopene
Diseases : Alcoholic Liver Disease, Liver Cancer, Liver Fibrosis, Liver Injury: Ischemia/reperfusion , Nonalcoholic fatty liver disease (NAFLD), Phthalate Toxicity
Pharmacological Actions : Antioxidants, Hepatoprotective
Problem Substances : Aflatoxin, Bisphenol A , Heavy Metals, Phthalates
[+]

Protective effects of polyphenols against endocrine disrupting chemicals.Jun 30, 2022

Pubmed Data : Food Sci Biotechnol. 2022 Jul ;31(8):905-934. Epub 2022 Jul 12. PMID: 35873371
Article Published Date : Jun 30, 2022
Study Type : Review
Additional Links
Substances : Polyphenols
Diseases : Bisphenol Toxicity, Phthalate Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
Problem Substances : Bisphenol A , Endocrine Disrupting Chemicals (EDCs), Phthalates
[+]

Quercetin ameliorates Di (2-ethylhexyl) phthalate-induced nephrotoxicity.Mar 31, 2022

Pubmed Data : Toxicol Res (Camb). 2022 Apr ;11(2):272-285. Epub 2022 Mar 3. PMID: 35510228
Article Published Date : Mar 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Quercetin
Diseases : Kidney Damage: Chemically-Induced, Phthalate Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Heme oxygenase-1 up-regulation, NF-kappaB Inhibitor, Nrf2 activation
Problem Substances : Phthalates
[+]

Reproductive toxic potential of phthalate compounds - State of art review Mar 03, 2021

Pubmed Data : Pharmacol Res. 2021 Mar 4 ;167:105536. Epub 2021 Mar 4. PMID: 33677105
Article Published Date : Mar 03, 2021
Study Type : Review
Additional Links
Diseases : Infertility: Female, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Results from this review have suggested that at least one phthalate has the ability to enhance tumour necrosis factor-α production from monocytes and macrophages.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2015 ;10(3):e0120083. Epub 2015 Mar 26. PMID: 25811352
Article Published Date : Dec 31, 2014
Study Type : Review
Additional Links
Additional Keywords : Cytokines, Problem Substance Synergy
Problem Substances : Phthalates
Adverse Pharmacological Actions : Tumor necrosis factorα (TNFα) up-regulation
[+]

Resveratrol reliefs DEHP-induced defects during human decidualization.Jun 14, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ecotoxicol Environ Saf. 2023 Jun 15 ;258:114931. Epub 2023 Apr 28. PMID: 37121080
Article Published Date : Jun 14, 2023
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol
Diseases : Phthalate Toxicity
Problem Substances : Phthalates
[+]

Several chemical exposures and nutrient deficiencies may be associated with the onset of autism spectrum disorder.Jan 01, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Neurosci. 2016 ;10:174. Epub 2016 Apr 20. PMID: 27147957
Article Published Date : Jan 01, 2016
Study Type : Review
Additional Links
Diseases : Autism, Autism Spectrum Disorders
Additional Keywords : Heavy Metals and Autism, Nutrient Deficiency Diseases
Problem Substances : Airborne Pollution, Bisphenol A , Pesticides, Phthalates, Tobacco
[+]

The migration test showed a great variation in the sum of migrated phthalic acid esters among the PET bottle brands.May 31, 2017

Pubmed Data : Talanta. 2017 Jun 1 ;168:291-297. Epub 2017 Mar 19. PMID: 28391856
Article Published Date : May 31, 2017
Study Type : In Vitro Study
Additional Links
Additional Keywords : Bottled Water
Problem Substances : Phthalates
[+]

The possible migration of phthalic acid esters from plastic packaging materials into the contents was indicated by the results of the present study.Nov 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Technol Biotechnol. 2017 Dec ;55(4):562-569. PMID: 29540990
Article Published Date : Nov 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Lemon Juice, Vinegar
Additional Keywords : Plastic Bottle
Problem Substances : Phthalates
[+]

There are several environmental factors associated with the development of ASD, including pesticides, phthalates, polychlorinated biphenyls, solvents, air pollutants, fragrances, glyphosate and heavy metals, especially aluminum used in vaccines.Mar 01, 2016

Pubmed Data : Environ Int. 2016 Mar ;88:288-298. Epub 2016 Jan 28. PMID: 26826339
Article Published Date : Mar 01, 2016
Study Type : Review
Additional Links
Diseases : Autism, Autism Spectrum Disorders
Additional Keywords : Heavy Metals and Autism, Vaccine Research
Problem Substances : Aluminum, Glyphosate, Heavy Metals, Pesticides, Phthalates, Polychlorinated biphenyls (PCBs), Synthetic Fragrance, Vaccine Adjuvants
Adverse Pharmacological Actions : Neurotoxic
[+]

These endocrine disrupting chemicals interfere with different cell signalling pathways involved in weight and glucose homeostasis.Nov 06, 2016

Pubmed Data : Endocrine. 2016 Nov 7. Epub 2016 Aug 7. PMID: 27822670
Article Published Date : Nov 06, 2016
Study Type : Review
Additional Links
Diseases : Bisphenol Toxicity, Diabetes Mellitus: Type 2, Obesity, Phthalate Toxicity
Problem Substances : Bisphenol A , Phthalates
Adverse Pharmacological Actions : Diabetogenic, Obesogenic
[+]

These results demonstrate down-regulation of ERα by endocrine-disrupting chemicals may influence the pathological state associated with hypoxia.Feb 20, 2019

Pubmed Data : Environ Pollut. 2019 Feb 21 ;248:774-781. Epub 2019 Feb 21. PMID: 30851587
Article Published Date : Feb 20, 2019
Study Type : In Vitro Study
Additional Links
Diseases : Bisphenol Toxicity, Breast Cancer
Additional Keywords : Risk Factors
Problem Substances : Bisphenol A , Endocrine Disrupting Chemicals (EDCs), Phthalates
[+]

These results support that some phthalates may be associated with higher odds of preterm birth in humans.Jul 23, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Int. 2019 Jul 24 ;130:104580. Epub 2019 Jul 24. PMID: 31351310
Article Published Date : Jul 23, 2019
Study Type : Review
Additional Links
Diseases : Phthalate Toxicity, Premature Birth
Additional Keywords : Risk Factors
Problem Substances : Phthalates
[+]

This review suggests that prenatal exposure to bisphenol A and phthalates may contribute to neurobehavioral outcomes in children.Mar 29, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Environ Res Public Health. 2021 Mar 30 ;18(7). Epub 2021 Mar 30. PMID: 33808331
Article Published Date : Mar 29, 2021
Study Type : Review
Additional Links
Diseases : Attention Deficit Hyperactivity Disorder, Bisphenol Toxicity, Prenatal Chemical Exposures
Additional Keywords : Risk Factors
Problem Substances : Bisphenol A , Phthalates
[+]

This study demonstrates for the first time the possible contribution of PAEs in perfumes to DNA damage.Sep 30, 2017

Pubmed Data : Environ Sci Pollut Res Int. 2017 Oct ;24(30):23903-23914. Epub 2017 Sep 5. PMID: 28875446
Article Published Date : Sep 30, 2017
Study Type : In Vitro Study
Additional Links
Diseases : DNA damage, Phthalate Toxicity
Additional Keywords : Risk Factors
Problem Substances : Perfume: Synthetic, Phthalates
Adverse Pharmacological Actions : Genotoxic
[+]

Various environmental toxins are associated with thyroid disruption.Dec 01, 2009

Pubmed Data : Altern Med Rev. 2009 Dec;14(4):326-46. PMID: 20030460
Article Published Date : Dec 01, 2009
Study Type : Commentary
Additional Links
Diseases : Autoimmune Thyroiditis, Hyperthyroidism, Hypothyroidism, Thyroid Cancer, Thyroid Diseases
Problem Substances : Dioxins, Organochlorine compounds, Organochlorine pesticides, Pesticides, Phthalates, Polybrominated diphenylethers (PBDEs), Polychlorinated biphenyls (PCBs)
Adverse Pharmacological Actions : Endocrine Disruptor
[+]

Worldwide bottled water occurrence of emerging contaminants.Jan 14, 2020

Pubmed Data : J Hazard Mater. 2020 06 15 ;392:122271. Epub 2020 Feb 14. PMID: 32311916
Article Published Date : Jan 14, 2020
Study Type : Review
Additional Links
Diseases : Bisphenol Toxicity, Phthalate Toxicity
Additional Keywords : Bottled Water, Microplastic, Plastic Bottle
Problem Substances : Bisphenol A , Phthalates

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Plastic revolutionized the world, but it did so with consequences. In recent years, more attention has been given to the potential dangers of plastic to human health and the environment. However, plastic remains one of the most widely used materials for everything from packaging to construction to consumer goods to manufacturing
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5 Proven Ways to Boost Testosterone Naturally
Written by Sayer Ji, Founder
Boosting testosterone is becoming all the rage today, but unless you activate your body's innate ability to do it naturally there are some very serious side effects that could get in the way of your health
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Written by GreenMedInfo Research Group
An astounding 19 pages of chemicals go into making one commonly used brand of air freshener, representing just how poorly regulated and toxic this increasingly popular class of consumer products is.
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Written by Dr. Roy Speiser
With chronic illness on the rise, people are desperately trying to stem the onslaught, all the while drinking and bathing in the most damaging problem of all. Think you have clean water? You might want to reconsider
Environmental Toxins Linked to Childhood Obesity
Written by Margie King, Health Coach
Are toys, pacifiers and even shampoo driving the epidemic of childhood obesity? Here's how to protect your family
Environmental Toxins Linked to Childhood Obesity
Written by Margie King, Health Coach
Are toys, pacifiers and even shampoo driving the epidemic of childhood obesity? Here's how to protect your family
Most Cheese Products Tainted with Dangerous Plastic Chemicals, Study Reveals
Written by Valerie Burke
A University of Washington study involving cheese products found endocrine-disrupting phthalates present in 29 of 30 samples tested
Are Toxic Chemicals Turning Boys Into Girls?
Written by Dr. Melody Milam Potter
Male births have been in decline for decades, while researchers say developmental genital damage from chemical exposure can become hereditable.
Is Your Uber Air Freshener Making You Sick?
Written by Kelly Brogan, M.D.
Millions are unwittingly being exposed to air fresheners laced with toxic, synthetic chemicals
Early Menopause Linked to Chemicals
Written by Margie King, Health Coach
Most women probably don’t want to rush into menopause. But chemicals you encounter every day could speed up the onset of menopause by close to 4 years
It's Worth It to Live a Life Without Plastic: Here's Why
Written by Deanna Minich, PhD
Plastic revolutionized the world, but it did so with consequences. In recent years, more attention has been given to the potential dangers of plastic to human health and the environment. However, plastic remains one of the most widely used materials for everything from packaging to construction to consumer goods to manufacturing
Are Toxic Chemicals Turning Boys Into Girls?
Written by Dr. Melody Milam Potter
Male births have been in decline for decades, while researchers say developmental genital damage from chemical exposure can become hereditable.
Breast Cancer and Leptin – How to Become More Proactive in Prevention
Written by Dr. Jill Tieman, DC
1 in 8 women will get breast cancer. While there is a lot we do not know about breast cancer, there is a lot we DO know about it. With science behind certain actions, we can accomplish our goal of breast cancer prevention.
Hormone Disrupters Found in Wines and Spirits
Written by Margie King, Health Coach
Is your lovely glass of cabernet infused with hormone-disrupting phthalates?
Exposure to Household Chemicals Affects Gut Microbiome
Written by GreenMedInfo Research Group
Study finds first evidence linking exposure to household chemicals to changes in the gut health of children
Exposure to Household Chemicals Affects Gut Microbiome
Written by GreenMedInfo Research Group
Study finds first evidence linking exposure to household chemicals to changes in the gut health of children
Early Menopause Linked to Chemicals
Written by Margie King, Health Coach
Most women probably don’t want to rush into menopause. But chemicals you encounter every day could speed up the onset of menopause by close to 4 years
Most Cheese Products Tainted with Dangerous Plastic Chemicals, Study Reveals
Written by Valerie Burke
A University of Washington study involving cheese products found endocrine-disrupting phthalates present in 29 of 30 samples tested
The Myth of Clean Water
Written by Dr. Roy Speiser
With chronic illness on the rise, people are desperately trying to stem the onslaught, all the while drinking and bathing in the most damaging problem of all. Think you have clean water? You might want to reconsider
Is Your Uber Air Freshener Making You Sick?
Written by Kelly Brogan, M.D.
Millions are unwittingly being exposed to air fresheners laced with toxic, synthetic chemicals

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