Proton-Pump Inhibitors

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102 Diseases Researched for Proton-Pump Inhibitors
NameACCKFocus
Pneumonia9101Locked
Magnesium Deficiency1088Locked
Gastroesophageal Reflux871Locked
Clostridium Infections770Locked
Dysbiosis958Locked
Myocardial Infarction441Locked
All-Cause Mortality440Locked
Chronic Kidney Disease (CKD)440Locked
Dementia340Locked
Diarrhea440Locked
Osteoporosis534Locked
Esophageal Cancer330Locked
Gastric Cancer724Locked
Vitamin C Deficiency221Locked
Childhood Infections220Locked
Diabetes Mellitus: Type 2220Locked
Drug-Induced Toxicity 220Locked
Gastroenteritis220Locked
Hepatic Cirrhosis220Locked
Hepatitis C220Locked
Hip Fracture220Locked
Liver Cirrhosis220Locked
Pancreatic Cancer120Locked
Rheumatoid Arthritis220Locked
Drug-Induced Nutrient Depletion: Vitamin B-12314Locked
Bone Fractures312Locked
Colitis212Locked
Colorectal Cancer212Locked
Enterobacteriaceae Infections212Locked
Acid Reflux211Locked
Alzheimer's Disease211Locked
Liver Disease211Locked
Nephritis211Locked
Acid Reflux: In Infants & Children110Locked
Anxiety110Locked
Asthma110Locked
Bone Diseases110Locked
Brain: Oxidative Stress110Locked
Cancers: All110Locked
Carcinoma: Non-Small-Cell Lung110Locked
Cardiac Mortality 110Locked
Cholangitis110Locked
Cirrhosis110Locked
Cognitive Decline/Dysfunction110Locked
Constipation110Locked
Coronary Artery Disease110Locked
Coronary Stenting 110Locked
Cystic Fibrosis110Locked
Cystic Fibrosis: Infections110Locked
Depression110Locked
Dyspepsia110Locked
Gastroesophageal Reflux: Infant and Children110Locked
Gastrointestinal Cancer110Locked
Hemodialysis110Locked
Hypothyroidism110Locked
Infant Infections110Locked
Infection: In Infants & Children 110Locked
Inflammatory Bowel Diseases110Locked
Irritable Bowel Syndrome110Locked
Kidney Cancer110Locked
Kidney Damage: Drug-Induced110Locked
Kidney Infection 110Locked
Liver Cancer110Locked
Liver Damage110Locked
Lung Cancer110Locked
Memory Disorders: Drug-Induced110Locked
Multiple Myeloma110Locked
Myocardial Infarction: Prevention110Locked
Nephrolithiasis110Locked
Neuroendocrine Tumors110Locked
Overactive Bladder110Locked
Oxidative Stress110Locked
Peritonitis: Bacterial110Locked
Respiratory Infections110Locked
Rosacea110Locked
Seizures110Locked
Streptococcus Infections110Locked
Stroke110Locked
Drug-Induced Nutrient Depletion: Iron24Locked
Anemia: Hemolytic13Locked
Encephalopathies13Locked
Seizures: Drug-Induced13Locked
Thrombocytopenia13Locked
Animal Diseases: Scrapie12Locked
Prion Diseases12Locked
Scrapie12Locked
Arrhythmias: Drug-Induced11Locked
Fractures: Bone11Locked
Gastrointestinal Infections11Locked
Hearing Loss11Locked
Lupus Erythematosus: Cutaneous11Locked
Mineral Deficiencies11Locked
Myopathies11Locked
Neutropenia: Drug-Induced11Locked
Periodontal Diseases11Locked
Pneumonia: Drug-Induced11Locked
Polymicrobial Small Bowel Bacterial Overgrowth11Locked
Polymyositis11Locked
Rebound Acid Hypersecretion Syndrome11Locked
Stomach Cancer11Locked
Vitamin B 12 Deficiency11Locked
Water-Electrolyte Imbalance11Locked
10 Adverse Pharmacological Actions Researched for Proton-Pump Inhibitors
NameACCKFocus
Immunosuppressive450Locked
Cardiotoxic642Locked
Gastrotoxic120Locked
Circulating Gastrin and Chromogranin A: Elevated110Locked
Neurotoxic110Locked
Neurotransmitter Interference110Locked
Renotoxic110Locked
Tumor Marker Elevation: Chromogranin 110Locked
Carcinogen14Locked
Carcinogenic12Locked
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View the Evidence:
129 Abstracts with Proton-Pump Inhibitors Research

[+]

Exposure to proton pump inhibitors and risk of pancreatic cancer.Jan 10, 2020

Pubmed Data : Expert Opin Drug Saf. 2020 Jan 11. Epub 2020 Jan 11. PMID: 31928106
Article Published Date : Jan 10, 2020
Study Type : Meta Analysis
Additional Links
Diseases : Pancreatic Cancer
Additional Keywords : Increased Risk
Problem Substances : Proton-Pump Inhibitors
[+]

Proton pump inhibitor use may increase the risk of hypomagnesemia.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2014 ;9(11):e112558. Epub 2014 Nov 13. PMID: 25394217
Article Published Date : Dec 31, 2013
Study Type : Meta Analysis, Review
Additional Links
Substances : Magnesium
Diseases : Magnesium Deficiency
Additional Keywords : Risk Factors
Problem Substances : Proton-Pump Inhibitors
[+]

This meta-analysesa found a dose-response between the proton pump inhibitors use and development of hypomagnesemia.Oct 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Medicine (Baltimore). 2019 Nov ;98(44):e17788. PMID: 31689852
Article Published Date : Oct 31, 2019
Study Type : Meta Analysis
Additional Links
Diseases : Magnesium Deficiency
Additional Keywords : Increased Risk
Problem Substances : Proton-Pump Inhibitors
[+]

This meta-analysis supports the hypothesis that proton pump inhibitors increase the risk of dementia.Nov 20, 2019

Pubmed Data : Eur J Clin Pharmacol. 2019 Nov 21. Epub 2019 Nov 21. PMID: 31748819
Article Published Date : Nov 20, 2019
Study Type : Meta Analysis
Additional Links
Diseases : Dementia
Additional Keywords : Increased Risk
Problem Substances : Proton-Pump Inhibitors
[+]

This study found possible evidence linking proton pump inhibitors use to an increased risk of community-acquired pneumonia.May 20, 2020

Pubmed Data : Int J Qual Health Care. 2020 May 21. Epub 2020 May 21. PMID: 32436582
Article Published Date : May 20, 2020
Study Type : Meta Analysis
Additional Links
Diseases : Pneumonia
Additional Keywords : Risk Factors
Problem Substances : Proton-Pump Inhibitors
[+]

A number of commonly used drugs interfere with the absorption of levothyroxine. Dec 01, 2009

Pubmed Data : Best Pract Res Clin Endocrinol Metab. 2009 Dec;23(6):781-92. PMID: 19942153
Article Published Date : Dec 01, 2009
Study Type : Human Study
Additional Links
Diseases : Hypothyroidism
Problem Substances : Antacids: Aluminium-Containing, Bile Acid Sequestrants, Calcium Carbonate, Ferrous Sulphate, Phosphate Binders, Proton-Pump Inhibitors, Raloxifene, Sucralfate
[+]

An increased risk of pneumonia was observed both immediately before and immediately after PPI initiation.Apr 20, 2022

Pubmed Data : BMJ Open. 2022 Apr 21 ;12(4):e060771. Epub 2022 Apr 21. PMID: 35450917
Article Published Date : Apr 20, 2022
Study Type : Human Study
Additional Links
Diseases : Pneumonia
Additional Keywords : Increased Risk
Problem Substances : Proton-Pump Inhibitors
[+]

Association between proton pump inhibitor use and overactive bladder risk in adults.Sep 17, 2024

Pubmed Data : Urology. 2024 Sep 18. Epub 2024 Sep 18. PMID: 39304071
Article Published Date : Sep 17, 2024
Study Type : Human Study
Additional Links
Diseases : Overactive Bladder
Problem Substances : Proton-Pump Inhibitors
[+]

Association between proton pump inhibitors and asthma: a population-based cohort study.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2020 ;11:607. Epub 2020 May 8. PMID: 32457614
Article Published Date : Dec 31, 2019
Study Type : Human Study
Additional Links
Diseases : Asthma
Additional Keywords : Increased Risk
Problem Substances : Proton-Pump Inhibitors
[+]

Association between proton pump inhibitors and severe hematological toxicity in patients receiving pemetrexed-based anticancer treatment.Dec 31, 2021

Pubmed Data : Lung Cancer. 2022 04 ;166:114-121. Epub 2022 Feb 24. PMID: 35263663
Article Published Date : Dec 31, 2021
Study Type : Human Study
Additional Links
Diseases : Cancers: All
Additional Keywords : Increased Risk
Problem Substances : Proton-Pump Inhibitors
[+]

Association of proton pump inhibitor use with survival and adverse effects outcomes in patients with multiple myeloma.Jan 04, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2024 Jan 5 ;14(1):591. Epub 2024 Jan 5. PMID: 38182614
Article Published Date : Jan 04, 2024
Study Type : Human Study
Additional Links
Diseases : Multiple Myeloma
Additional Keywords : Increased Risk
Problem Substances : Proton-Pump Inhibitors
[+]

Children exposed to proton pump inhibitor therapy are at higher risk for the development of Clostridium difficile-associated disease. Dec 29, 2009

Pubmed Data : Aliment Pharmacol Ther. 2009 Dec 29. Epub 2009 Dec 29. PMID: 20047577
Article Published Date : Dec 29, 2009
Study Type : Human Study
Additional Links
Diseases : Acid Reflux: In Infants & Children, Childhood Infections, Clostridium Infections, Infant Infections
Additional Keywords : Iatrogenic Disease
Problem Substances : Proton-Pump Inhibitors
[+]

Chronic PPI use resulted in significant increases in CGA (including the tumor marker chromogranin A) and significant increases in gastrin compared to controls. Mar 28, 2012

Pubmed Data : Pancreas. 2012 Mar 28. Epub 2012 Mar 28. PMID: 22460728
Article Published Date : Mar 28, 2012
Study Type : Human Study
Additional Links
Diseases : Neuroendocrine Tumors
Problem Substances : Proton-Pump Inhibitors
Adverse Pharmacological Actions : Circulating Gastrin and Chromogranin A: Elevated, Tumor Marker Elevation: Chromogranin
[+]

Community prescribed ASMs were associated with increased rates of C. difficile and Campylobacter positive gastroenteritis.Jan 04, 2017

Pubmed Data : Br J Clin Pharmacol. 2017 Jan 5. Epub 2017 Jan 5. PMID: 28054368
Article Published Date : Jan 04, 2017
Study Type : Human Study
Additional Links
Diseases : Gastroenteritis
Additional Keywords : Increased Risk
Problem Substances : Proton-Pump Inhibitors
[+]

Concomitant use of a proton pump inhibitor and clopidogrel compared with clopidogrel alone was associated with a higher rate of major adverse cardiovascular events within 1 year after coronary stent placement.Aug 01, 2010

Pubmed Data : Pharmacotherapy. 2010 Aug;30(8):787-96. PMID: 20653354
Article Published Date : Aug 01, 2010
Study Type : Human Study
Additional Links
Diseases : Coronary Artery Disease, Coronary Stenting
Additional Keywords : Drug Interaction
Problem Substances : Clopidogrel, Proton-Pump Inhibitors
[+]

Current use of gastric acid-suppressive therapy was associated with an increased risk of community-acquired pneumonia.Oct 27, 2004

Pubmed Data : JAMA. 2004 Oct 27;292(16):1955-60. PMID: 15507580
Article Published Date : Oct 27, 2004
Study Type : Human Study
Additional Links
Diseases : Pneumonia
Problem Substances : Histamine Receptor Antagonists, Proton-Pump Inhibitors
Adverse Pharmacological Actions : Immunosuppressive
[+]

Deleterious effect of proton pump inhibitors on the disease course of cirrhosis.Aug 26, 2019

Pubmed Data : Eur J Gastroenterol Hepatol. 2019 Aug 27. Epub 2019 Aug 27. PMID: 31464790
Article Published Date : Aug 26, 2019
Study Type : Human Study
Additional Links
Diseases : Cirrhosis, Peritonitis: Bacterial
Additional Keywords : Increased Risk
Problem Substances : Proton-Pump Inhibitors
[+]

Drug use is associated with lower plasma magnesium levels in geriatric outpatients.Dec 05, 2018

Pubmed Data : Clin Nutr. 2018 Dec 6. Epub 2018 Dec 6. PMID: 30581015
Article Published Date : Dec 05, 2018
Study Type : Human Study
Additional Links
Diseases : Magnesium Deficiency
Additional Keywords : Increased Risk
Problem Substances : Metformin , Proton-Pump Inhibitors, Statin Drugs
[+]

Exposure to Proton pump inhibitors is associated with higher numbers of hospitalizations for pulmonary exacerbation in cystic fibrosis patients.Sep 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Gastroenterology Res. 2017 Oct ;10(5):288-293. Epub 2017 Oct 26. PMID: 29118869
Article Published Date : Sep 30, 2017
Study Type : Human Study
Additional Links
Diseases : Cystic Fibrosis
Additional Keywords : Increased Risk
Problem Substances : Proton-Pump Inhibitors
[+]

Hypomagnesemia and hypocitraturia associated with PPI exposure may contribute to kidney stone risk. May 01, 2022

Pubmed Data : Urolithiasis. 2022 May 2. Epub 2022 May 2. PMID: 35499617
Article Published Date : May 01, 2022
Study Type : Human Study
Additional Links
Diseases : Nephrolithiasis
Additional Keywords : Increased Risk
Problem Substances : Proton-Pump Inhibitors
[+]

In addition to ipilimumab use, chronic use of PPIs may be associated with ICI colitis in patients with mRCC.Jan 31, 2022

Pubmed Data : Clin Genitourin Cancer. 2022 Feb 1. Epub 2022 Feb 1. PMID: 35277350
Article Published Date : Jan 31, 2022
Study Type : Human Study
Additional Links
Diseases : Colitis, Kidney Cancer
Additional Keywords : Increased Risk
Problem Substances : Proton-Pump Inhibitors
[+]

Lactobacillus paracasei F19 supplementation prevents bowel symptom onset in patients on long-term proton pump inhibitors.Mar 31, 2015

Pubmed Data : Dig Liver Dis. 2015 Apr ;47(4):273-9. Epub 2015 Jan 19. PMID: 25660822
Article Published Date : Mar 31, 2015
Study Type : Human Study
Additional Links
Substances : Lactobacillus paracasei
Diseases : Dysbiosis, Irritable Bowel Syndrome
Pharmacological Actions : Gastrointestinal Agents, Gastroprotective
Problem Substances : Proton-Pump Inhibitors
[+]

Lactobacillus probiotics could restore the gastric barrier effect in patients treated with proton pump inhibitors. Sep 30, 2012

Pubmed Data : J Clin Gastroenterol. 2012 Oct ;46 Suppl:S18-26. PMID: 22955351
Article Published Date : Sep 30, 2012
Study Type : Human Study
Additional Links
Substances : Lactobacillus delbrueckii Subsp, Lactobacillus plantarum, Lactobacillus probiotics, Lactobacillus rhamnosus
Diseases : Dysbiosis, Gastroesophageal Reflux
Pharmacological Actions : Gastroprotective
Additional Keywords : Increased Risk, Microbiota, Risk Reduction, Significant Treatment Outcome
Problem Substances : Proton-Pump Inhibitors
[+]

Long term use of proton pump inhibitors is associated with increased risk of oesophageal adenocarcinoma in the absence of other risk factors.Dec 31, 2017

Pubmed Data : Cancer Epidemiol. 2018 04 ;53:172-177. Epub 2018 Feb 22. PMID: 29477057
Article Published Date : Dec 31, 2017
Study Type : Human Study
Additional Links
Diseases : Esophageal Cancer
Additional Keywords : Increased Risk
Problem Substances : Proton-Pump Inhibitors
[+]

Long-term PPI was significantly associated with osteoporosis.May 01, 2022

Pubmed Data : J Gastroenterol Hepatol. 2022 May 2. Epub 2022 May 2. PMID: 35501296
Article Published Date : May 01, 2022
Study Type : Human Study
Additional Links
Diseases : Osteoporosis
Additional Keywords : Risk Factors
Problem Substances : Proton-Pump Inhibitors
[+]

Long-term proton pump inhibitor therapy is associated with an increased risk of hip fracture.Dec 27, 2006

Pubmed Data : JAMA. 2006 Dec 27;296(24):2947-53. PMID: 17190895
Article Published Date : Dec 27, 2006
Study Type : Human Study
Additional Links
Diseases : Bone Fractures, Hip Fracture, Osteoporosis
Problem Substances : Proton-Pump Inhibitors
[+]

Long-term proton pump inhibitor therapy leads to small bowel bacterial overgrowth.Nov 27, 2017

Pubmed Data : J Breath Res. 2017 Nov 28. Epub 2017 Nov 28. PMID: 29182524
Article Published Date : Nov 27, 2017
Study Type : Human Study
Additional Links
Diseases : Dysbiosis
Additional Keywords : Microbiota
Problem Substances : Proton-Pump Inhibitors
[+]

Long-term Proton pump inhibitor use has an effect on the gut microbiome.Feb 28, 2016

Pubmed Data : Aliment Pharmacol Ther. 2016 Feb 29. Epub 2016 Feb 29. PMID: 26923470
Article Published Date : Feb 28, 2016
Study Type : Human Study
Additional Links
Diseases : Clostridium Infections
Additional Keywords : Increased Risk, Microbiome
Problem Substances : Proton-Pump Inhibitors
[+]

Long-term proton pump inhibitors use is associated with risk of bone complications.Feb 28, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Tunis Med. 2018 Mar ;96(3):193-197. PMID: 30325487
Article Published Date : Feb 28, 2018
Study Type : Human Study
Additional Links
Diseases : Bone Diseases, Osteoporosis
Additional Keywords : Increased Risk
Problem Substances : Proton-Pump Inhibitors
[+]

Long-term use of omeprazole is suggested to induce an oxidative stress condition, which causes neurotoxicity and cognitive decline.Feb 21, 2021

Pubmed Data : J Pharm Pharmacol. 2021 Feb 22. Epub 2021 Feb 22. PMID: 33793790
Article Published Date : Feb 21, 2021
Study Type : Human Study
Additional Links
Diseases : Brain: Oxidative Stress, Cognitive Decline/Dysfunction
Problem Substances : Omeprazole (trade name Prilosec)
Adverse Pharmacological Actions : Neurotransmitter Interference
[+]

Medically treated patients with mild or absent GERD symptoms have significantly higher odds of adenocarcinogenesis compared with medically treated patients with severe GERD symptoms.Jul 01, 2011

Pubmed Data : Arch Surg. 2011 Jul;146(7):851-8. PMID: 21768433
Article Published Date : Jul 01, 2011
Study Type : Human Study
Additional Links
Diseases : Esophageal Cancer, Gastroesophageal Reflux
Problem Substances : Proton-Pump Inhibitors
[+]

Modulation of the oxidative plasmatic state in gastroesophageal reflux disease with the addition of rich water molecular hydrogen.Apr 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cell Mol Med. 2018 May ;22(5):2750-2759. Epub 2018 Mar 7. PMID: 29512923
Article Published Date : Apr 30, 2018
Study Type : Human Study
Additional Links
Substances : Hydrogen Water, Water: Electrolyzed Reduced
Diseases : Gastroesophageal Reflux, Oxidative Stress
Pharmacological Actions : Antioxidants
Problem Substances : Proton-Pump Inhibitors
[+]

Omeprazole has been linked to interstitial nephritis.May 01, 2010

Pubmed Data : Br J Clin Pharmacol. 2010 May;69(5):516-9. PMID: 20573087
Article Published Date : May 01, 2010
Study Type : Human Study
Additional Links
Diseases : Drug-Induced Toxicity , Nephritis
Problem Substances : Omeprazole (trade name Prilosec)
[+]

Omeprazole treatment have caused considerable changes in stool culture results.Feb 28, 2017

Pubmed Data : Clin Res Hepatol Gastroenterol. 2017 Mar 1. Epub 2017 Mar 1. PMID: 28258834
Article Published Date : Feb 28, 2017
Study Type : Human Study
Additional Links
Additional Keywords : Risk Factors
Problem Substances : Omeprazole (trade name Prilosec), Proton-Pump Inhibitors
Adverse Pharmacological Actions : Gastrotoxic
[+]

Over-use of proton pump inhibitors may be fuelling the current epidemic of Clostridium difficile-associated diarrhoea.Sep 01, 2008

Pubmed Data : J Hosp Infect. 2008 Sep;70(1):1-6. Epub 2008 Jul 3. PMID: 18602190
Article Published Date : Sep 01, 2008
Study Type : Human Study
Additional Links
Diseases : Clostridium Infections, Diarrhea, Drug-Induced Toxicity
Problem Substances : Proton-Pump Inhibitors
[+]

Patients in hospital who received proton pump inhibitors were at increased risk of Clostridium difficile diarrhea.Jul 06, 2004

Pubmed Data : CMAJ. 2004 Jul 6;171(1):33-8. PMID: 15238493
Article Published Date : Jul 06, 2004
Study Type : Human Study
Additional Links
Diseases : Clostridium Infections, Diarrhea
Problem Substances : Histamine Receptor Antagonists, Proton-Pump Inhibitors
Adverse Pharmacological Actions : Immunosuppressive
[+]

Patients with rheumatoid arthritis found a significantly increased risk of acute kidney injury associated with the use of proton pump inhibitors.Dec 31, 2017

Pubmed Data : Drug Saf. 2018 08 ;41(8):817-826. PMID: 29603109
Article Published Date : Dec 31, 2017
Study Type : Human Study
Additional Links
Diseases : Kidney Infection , Rheumatoid Arthritis
Additional Keywords : Risk Factors
Problem Substances : Proton-Pump Inhibitors
[+]

Prolonged acid suppression therapy with PPIs or H2 blockers may result in serum vitamin B12 deficiency.Oct 20, 2020

Pubmed Data : Ir J Med Sci. 2020 Oct 21. Epub 2020 Oct 21. PMID: 33085017
Article Published Date : Oct 20, 2020
Study Type : Human Study
Additional Links
Diseases : Drug-Induced Nutrient Depletion: Vitamin B-12
Additional Keywords : Increased Risk
Problem Substances : Proton-Pump Inhibitors
[+]

Prolonged proton pump inhibitors use was associated with an increased risk of rosacea.Jun 30, 2020

Pubmed Data : J Dermatol. 2020 Jul 1. Epub 2020 Jul 1. PMID: 32613686
Article Published Date : Jun 30, 2020
Study Type : Human Study
Additional Links
Diseases : Rosacea
Additional Keywords : Increased Risk
Problem Substances : Proton-Pump Inhibitors
[+]

Prolonged use of a proton pump inhibitor reduces microbial diversity: implications for Clostridium difficile susceptibility.Dec 31, 2013

Pubmed Data : Microbiome. 2014 ;2:42. Epub 2014 Nov 25. PMID: 25426290
Article Published Date : Dec 31, 2013
Study Type : Human Study
Additional Links
Diseases : Clostridium Infections
Problem Substances : Proton-Pump Inhibitors
[+]

Prolonged use of proton pump inhibitors and risk of type 2 diabetes.Apr 15, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Clin Endocrinol Metab. 2022 Apr 16. Epub 2022 Apr 16. PMID: 35428888
Article Published Date : Apr 15, 2022
Study Type : Human Study
Additional Links
Diseases : Diabetes Mellitus: Type 2
Additional Keywords : Increased Risk
Problem Substances : Proton-Pump Inhibitors
[+]

Proton pump inhibitor alters oral microbiome in gastrointestinal tract of healthy volunteers.Nov 03, 2017

Pubmed Data : J Gastroenterol Hepatol. 2017 Nov 4. Epub 2017 Nov 4. PMID: 29105152
Article Published Date : Nov 03, 2017
Study Type : Human Study
Additional Links
Diseases : Dysbiosis
Additional Keywords : Microbiome
Problem Substances : Proton-Pump Inhibitors
[+]

Proton pump inhibitor therapy may increased the risk of clostridium difficile-associated diarrhea.May 01, 2007

Pubmed Data : J Natl Med Assoc. 2007 May;99(5):500-4. PMID: 17534007
Article Published Date : May 01, 2007
Study Type : Human Study
Additional Links
Diseases : Clostridium Infections, Diarrhea
Additional Keywords : Increased Risk
Problem Substances : Proton-Pump Inhibitors
[+]

Proton pump inhibitor treatment is associated with the severity of liver disease and increased mortality in patients with cirrhosis.Dec 18, 2014

Pubmed Data : Aliment Pharmacol Ther. 2014 Dec 19. Epub 2014 Dec 19. PMID: 25523381
Article Published Date : Dec 18, 2014
Study Type : Human Study
Additional Links
Diseases : Liver Cirrhosis, Liver Disease
Problem Substances : Proton-Pump Inhibitors
[+]

Proton pump inhibitor use and risk of depression and anxiety in children.Jan 10, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Transl Sci. 2022 Jan 11. Epub 2022 Jan 11. PMID: 35015332
Article Published Date : Jan 10, 2022
Study Type : Human Study
Additional Links
Diseases : Anxiety, Depression
Additional Keywords : Increased Risk
Problem Substances : Proton-Pump Inhibitors
[+]

Proton pump inhibitor use increases mortality and hepatic decompensation in liver cirrhosis.Sep 06, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : World J Gastroenterol. 2019 Sep 7 ;25(33):4933-4944. PMID: 31543684
Article Published Date : Sep 06, 2019
Study Type : Human Study
Additional Links
Diseases : All-Cause Mortality, Liver Cirrhosis
Additional Keywords : Increased Risk
Problem Substances : Proton-Pump Inhibitors
[+]

Proton pump inhibitor use represents an independent risk factor for myocardial infarction.Nov 14, 2014

Pubmed Data : Int J Cardiol. 2014 Nov 15 ;177(1):292-7. Epub 2014 Sep 28. PMID: 25499395
Article Published Date : Nov 14, 2014
Study Type : Human Study
Additional Links
Diseases : Myocardial Infarction, Myocardial Infarction: Prevention
Problem Substances : Proton-Pump Inhibitors
Adverse Pharmacological Actions : Cardiotoxic
[+]

Proton pump inhibitor use was associated with an increased risk of cholangitis.Aug 24, 2019

Pubmed Data : Aliment Pharmacol Ther. 2019 Aug 25. Epub 2019 Aug 25. PMID: 31448440
Article Published Date : Aug 24, 2019
Study Type : Human Study
Additional Links
Diseases : Cholangitis
Additional Keywords : Increased Risk
Problem Substances : Proton-Pump Inhibitors
[+]

Proton pump inhibitor use was associated with an increased risk of gastric and oesophageal cancer.Aug 20, 2019

Pubmed Data : Cancer Epidemiol. 2019 Aug 21 ;62:101585. Epub 2019 Aug 21. PMID: 31445426
Article Published Date : Aug 20, 2019
Study Type : Human Study
Additional Links
Diseases : Esophageal Cancer, Gastric Cancer
Additional Keywords : Increased Risk
Problem Substances : Proton-Pump Inhibitors
[+]

Proton pump inhibitors and risk of calcium pyrophosphate deposition in a population-based study.Mar 03, 2022

Pubmed Data : Arthritis Care Res (Hoboken). 2022 Mar 4. Epub 2022 Mar 4. PMID: 35245410
Article Published Date : Mar 03, 2022
Study Type : Human Study
Additional Links
Additional Keywords : Risk Factors
Problem Substances : Proton-Pump Inhibitors
[+]

Proton pump inhibitors are associated with accelerated development of cirrhosis, and hepatocellular carcinoma in patients with hepatitis C infection.Nov 02, 2017

Pubmed Data : Aliment Pharmacol Ther. 2017 Nov 3. Epub 2017 Nov 3. PMID: 29105111
Article Published Date : Nov 02, 2017
Study Type : Human Study
Additional Links
Diseases : Hepatic Cirrhosis, Hepatitis C, Liver Cancer
Additional Keywords : Increased Risk
Problem Substances : Proton-Pump Inhibitors
[+]

Proton pump inhibitors are not superior to placebo and increase the risk of respiratory tract infections in infants with symptoms of GERD.Apr 01, 2009

Pubmed Data : J Pediatr. 2009 Apr;154(4):514-520.e4. Epub 2008 Dec 3. PMID: 19054529
Article Published Date : Apr 01, 2009
Study Type : Human Study
Additional Links
Diseases : Gastroesophageal Reflux, Gastroesophageal Reflux: Infant and Children
Additional Keywords : Drugs that are Worse than Placebo
Problem Substances : Lansoprazole
[+]

Proton pump inhibitors increase the severity of hepatic encephalopathy in cirrhotic patients.Jun 26, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : World J Hepatol. 2019 Jun 27 ;11(6):522-530. PMID: 31293720
Article Published Date : Jun 26, 2019
Study Type : Human Study
Additional Links
Diseases : Hepatic Cirrhosis
Additional Keywords : Increased Risk
Problem Substances : Proton-Pump Inhibitors
[+]

Proton pump inhibitors prescription was associated with greater risk of pneumonia in the second year of treatment.Apr 19, 2018

Pubmed Data : J Am Geriatr Soc. 2018 Apr 20. Epub 2018 Apr 20. PMID: 29676433
Article Published Date : Apr 19, 2018
Study Type : Human Study
Additional Links
Diseases : Pneumonia
Additional Keywords : Increased Risk
Problem Substances : Proton-Pump Inhibitors
[+]

Proton pump inhibitors reduce the bioavailability of dietary vitamin C.Sep 15, 2005

Pubmed Data : Aliment Pharmacol Ther. 2005 Sep 15;22(6):539-45. PMID: 16167970
Article Published Date : Sep 15, 2005
Study Type : Human Study