Retinyl palmitate

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2 Diseases Researched for Retinyl palmitate

Name	AC	CK	Focus
Prenatal Chemical Exposures	2	4
Birth Defects	1	2

4 Adverse Pharmacological Actions Researched for Retinyl palmitate

Name	AC	CK
Teratogenic	2	4
Clastogenic	1	1
Mutagenic	1	1
Photomutagenic	1	1

Research Articles 6
Cumulative Knowledge Score 9
Overall Research Rating GOOD

View the Evidence:
6 Abstracts with Retinyl palmitate Research

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High dietary intake of preformed vitamin A appears to be teratogenic. Among the babies born to women who took more than 10,000 IU of preformed vitamin A per day in the form of supplements, we estimate that about 1 infant in 57 had a malformation attributaNov 23, 1995

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : N Engl J Med. 1995 Nov 23 ;333(21):1369-73. PMID: 7477116

Article Published Date : Nov 23, 1995

Study Type : Human Study

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Substances : Vitamin A

Diseases : Abnormalities, Birth Defects, Drug-Induced, Prenatal Nutrition: Prevention of Problems

Problem Substances : Retinyl palmitate

Adverse Pharmacological Actions : Teratogenic

[+]

Retinyl (retinol) palmitate feeding results in abnormal development and abnormalities in the embryos of mice.Apr 01, 2003

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Pubmed Data : Biol Pharm Bull. 2003 Apr;26(4):553-6. PMID: 12673043

Article Published Date : Apr 01, 2003

Study Type : Animal Study

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Diseases : Prenatal Chemical Exposures

Problem Substances : Retinyl palmitate

Adverse Pharmacological Actions : Teratogenic

[+]

Retinyl palmitate exhibits teratrogenic properties. Dec 01, 2009

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Pubmed Data : Indian J Exp Biol. 2009 Dec ;47(12):949-54. PMID: 20329697

Article Published Date : Dec 01, 2009

Study Type : Animal Study

Additional Links

Diseases : Birth Defects, Prenatal Chemical Exposures

Problem Substances : Retinyl palmitate

Adverse Pharmacological Actions : Teratogenic

[+]

Retinyl palmitate induces malformations in the embryos of pregnant rats.Sep 01, 1996

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Pubmed Data : Pharmacol Toxicol. 1996 Sep;79(3):131-5. PMID: 8884871

Article Published Date : Sep 01, 1996

Study Type : Animal Study

Additional Links

Diseases : Birth Defects, Prenatal Chemical Exposures

Problem Substances : Retinyl palmitate

Adverse Pharmacological Actions : Teratogenic

[+]

Punicalagin could effectively attenuate FFA-induced lipotoxicity by activating Keap1-Nrf2 cytoprotective signaling pathway.Apr 30, 2016

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Pubmed Data : Mol Nutr Food Res. 2016 May ;60(5):1139-49. Epub 2016 Apr 14. PMID: 26989875

Article Published Date : Apr 30, 2016

Study Type : In Vitro Study

Additional Links

Substances : Punicalagin

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Antioxidants, Cytoprotective, Hepatoprotective, Nrf2 activation

Problem Substances : Retinyl palmitate

[+]

Retinyl palmitate is photomutagenic in combination with UVA exposure in mouse lymphoma cells, with a clastogenic mode-of-action.Nov 01, 2005

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Pubmed Data : Toxicol Sci. 2005 Nov;88(1):142-9. Epub 2005 Aug 17. PMID: 16107546

Article Published Date : Nov 01, 2005

Study Type : In Vitro Study

Additional Links

Problem Substances : Retinyl palmitate

Adverse Pharmacological Actions : Clastogenic, Mutagenic, Photomutagenic

Research Articles 6
Cumulative Knowledge Score 9
Overall Research Rating GOOD

Retinyl palmitate Related Articles

Why Is Birth Defect-Linked Vitamin A Used In Prenatals?

Written by Sayer Ji, Founder

A human study published in the New England Journal of Medicine in 1995 showed that women who consumed 10,000 IU of preformed vitamin A from supplements per day had 4.8 times the rate of birth defects than those who consumed 5,000 IU per day while pregnant. The increased frequency of defects was concentrated among babies born to women who consumed high levels of vitamin A before the seventh week of gestation.

Why Is Birth Defect-Linked Vitamin A Used In Prenatals?

Written by Sayer Ji, Founder

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This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

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Retinyl palmitate is a Sub of the following Topic

View the Evidence: 6 Abstracts with Retinyl palmitate Research

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High dietary intake of preformed vitamin A appears to be teratogenic. Among the babies born to women who took more than 10,000 IU of preformed vitamin A per day in the form of supplements, we estimate that about 1 infant in 57 had a malformation attributaNov 23, 1995

Click here to read the entire abstract

Retinyl (retinol) palmitate feeding results in abnormal development and abnormalities in the embryos of mice.Apr 01, 2003

Click here to read the entire abstract

Retinyl palmitate exhibits teratrogenic properties. Dec 01, 2009

Click here to read the entire abstract

Retinyl palmitate induces malformations in the embryos of pregnant rats.Sep 01, 1996

Click here to read the entire abstract

Punicalagin could effectively attenuate FFA-induced lipotoxicity by activating Keap1-Nrf2 cytoprotective signaling pathway.Apr 30, 2016

Click here to read the entire abstract

Retinyl palmitate is photomutagenic in combination with UVA exposure in mouse lymphoma cells, with a clastogenic mode-of-action.Nov 01, 2005

Click here to read the entire abstract

Retinyl palmitate Related Articles

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Retinyl palmitate

View the Evidence:
6 Abstracts with Retinyl palmitate Research