Simvastatin

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157 Diseases Researched for Simvastatin
NameACCKFocus
Statin-Induced Pathologies105475Locked
Myopathies1476Locked
Chemically-Induced Liver Damage759Locked
High Cholesterol450Locked
Rhabdomyolysis1243Locked
Cancers: All240Locked
Drug-Induced Nutrient Depletion: Statin Drugs738Locked
Pancreatitis736Locked
Low Testosterone431Locked
Diabetes Mellitus: Type 2230Locked
Insulin Resistance230Locked
Cognitive Decline/Dysfunction424Locked
Hyperlipidemia424Locked
Dyslipidemias322Locked
Oxidative Stress322Locked
Cataract321Locked
Mitochondrial Dysfunction 821Locked
Aortic Stenosis120Locked
Coronary Artery Disease220Locked
Dietary Fatty Acid Imbalance: Omega3/Omega6 Ratio220Locked
Hyperglycemia120Locked
Drug-Induced Toxicity 417Locked
Peripheral Neuropathies316Locked
Coenzyme Q10 Deficiency315Locked
Liver Damage315Locked
Mitochondrial Myopathies515Locked
Memory Disorders314Locked
Immune Disorders: Low Immune Function313Locked
Cardiovascular Diseases212Locked
Depression211Locked
Aldosterone levels: Low110Locked
Atherosclerosis110Locked
Blood Platelet Disorders110Locked
Cardiomyopathy110Locked
Copper Deficiency110Locked
Creatine Phosphokinase (CK): Elevated110Locked
Diabetes Mellitus: Type 2: Prevention110Locked
Diabetes: Cardiovascular Illness110Locked
Eczema110Locked
Endothelial Dysfunction110Locked
Esophageal Cancer110Locked
Fibromyalgia110Locked
Gastrointestinal Complaints110Locked
Kidney Cancer110Locked
Kidney Failure110Locked
Liver Disease110Locked
Liver Failure: Drug Induced110Locked
Mitochondrial Diseases110Locked
Multiple Myeloma110Locked
Myotoxicity110Locked
Omega-3 Fatty Acid Deficiency110Locked
Polyneuropathies110Locked
Psoriasis110Locked
Testicular Cancer110Locked
Testosterone: Too Low110Locked
Triglycerides: Elevated110Locked
Zinc Deficiency110Locked
Neuropathies49Locked
Myasthenia Gravis37Locked
Lichenoid Dermatitis26Locked
Lupus-Like Syndrome26Locked
Memory Disorders: Drug-Induced26Locked
Myositis26Locked
Rhabdomyolysis: Fatal26Locked
Tendon Rupture26Locked
Cholestasis25Locked
Thyroid Cancer25Locked
Demyelinating Diseases34Locked
Inflammation24Locked
Myocardial Ischemia24Locked
Acute generalized exanthematous pustulosis (AGEP) 13Locked
Arthralgia13Locked
Ataxia13Locked
Autoimmune Diseases13Locked
Bipolar Disorder13Locked
Cheilitis13Locked
Compartment Syndromes13Locked
Congestive Heart Failure13Locked
Cutaneous Eruptions13Locked
Dermatitis: Actinic13Locked
Dermatomyositis13Locked
Elevated: ALT13Locked
Elevated: Creatinine Kinase13Locked
Eosinophilia13Locked
GGT13Locked
Hepatitis13Locked
Hepatitis: Acute13Locked
Hepatitis: Autoimmune 13Locked
Hepatitis: Cholestatic13Locked
Hypothyroidism13Locked
Jaundice13Locked
Kidney Damage: Drug-Induced13Locked
Kidney Failure: Acute13Locked
Kidney Transplant13Locked
Lactic Acidosis13Locked
Lens Diseases23Locked
Lichen Planus13Locked
Liver Damage: Drug-Induced13Locked
Lung Diseases: Interstitial13Locked
Lupus Erythematosus: Cutaneous13Locked
Lupus Erythematosus: Cutaneous: Subacute13Locked
Memory Loss13Locked
Mood Disorders13Locked
Multiple Sclerosis23Locked
Myoglobinuria13Locked
Myositis Migrans13Locked
Neuroleptic Malignant Syndrome13Locked
Neurotoxicity33Locked
Nightmare13Locked
Organ Transplantation: Liver13Locked
Pleurisy13Locked
Pneumonia: Interstitial13Locked
Polymyositis13Locked
Psychiatric Disorders13Locked
Psychological Well-Being13Locked
Skeletal Muscle Changes: Endoplasmic Reticulum Stress13Locked
Skeletal Muscle: Changes to MHC I expression13Locked
Sleep Disorders13Locked
Systemic Lupus Erythematosus13Locked
Tendinopathy13Locked
Ulcerative Colitis13Locked
Urticarial Vasculitis13Locked
Vasculitis13Locked
Anxiety Disorders12Locked
Blood-Brain-Barrier Disorders12Locked
Brain Damage22Locked
Brain Inflammation 12Locked
Eye Diseases12Locked
High Fat Diet12Locked
Hypertension12Locked
Lens Damage12Locked
Leukodystrophy12Locked
Leukodystrophy: Metachromatic12Locked
Lung Diseases12Locked
Male Reproductive Development Abnormalities12Locked
Myopathy12Locked
Organ Transplantation12Locked
Ovarian Diseases22Locked
Prenatal Chemical Exposures12Locked
Proteoglycan Expression: Down-Regulation of Chondroitin Sulfate12Locked
Proteoglycan Expression: Pathological12Locked
Spinal Cord Injuries12Locked
Tumors12Locked
Wound Healing12Locked
Cochlear Neuronal Damage11Locked
DNA damage11Locked
Dementia11Locked
Hearing Disorders11Locked
Hypoadrenalism11Locked
Insulin-like Growth Factor-1: Signaling Abnormalities11Locked
Lens Opacities11Locked
Ovarian Failure11Locked
Ovulation Disorders11Locked
Pregnancy: Environmental Exposures11Locked
Prostate Diseases11Locked
Suicidal Behavior11Locked
Violence11Locked
22 Adverse Pharmacological Actions Researched for Simvastatin

View the Evidence:
165 Abstracts with Simvastatin Research

[+]
Pubmed Data : Am J Cardiol. 2010 Dec 1;106(11):1634-9. Epub 2010 Oct 14. PMID: 21094366
Study Type : Meta Analysis
Additional Links
Diseases : Aortic Stenosis
[+]
Pubmed Data : Heart Lung Circ. 2009 Oct;18(5):343-6. Epub 2009 Jul 7. PMID: 19586799
Study Type : Meta Analysis
Additional Links
Diseases : Cancers: All
Problem Substances : Simvastatin
Adverse Pharmacological Actions : Carcinogenic
[+]
Pubmed Data : Drug Saf. 2006 ;29(12):1123-32. PMID: 17147459
Study Type : Meta Analysis
Additional Links
Problem Substances : Simvastatin, Statin Drugs
[+]
Pubmed Data : Diabetes Res Clin Pract. 2010 Jan ;87(1):98-107. Epub 2009 Nov 12. PMID: 19913318
Study Type : Meta Analysis
Additional Links
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Simvastatin
Adverse Pharmacological Actions : Diabetogenic, Endocrine Disruptor: Insulin Resistance
[+]
Pubmed Data : J Am Coll Cardiol. 2007 Jul 31 ;50(5):409-18. Epub 2007 Jul 16. PMID: 17662392
Study Type : Meta Analysis
Additional Links
Adverse Pharmacological Actions : Carcinogenic
[+]
Pubmed Data : Arch Intern Med. 2001 Sep 10 ;161(16):2021-6. PMID: 11525705
Study Type : Human Study
Additional Links
Pharmacological Actions : Anti-Bacterial Agents
Problem Substances : Simvastatin, Statin Drugs
[+]
Pubmed Data : Nutr Metab Cardiovasc Dis. 2005 Feb ;15(1):36-41. PMID: 15871849
Study Type : Human Study
[+]
Pubmed Data : Clin Pharmacol Ther. 1998 Nov ;64(5):477-83. PMID: 9834039
Study Type : Human Study
Additional Links
Substances : Grapefruit
Problem Substances : Simvastatin, Statin Drugs
[+]
Pubmed Data : Hautarzt. 1995 Feb ;46(2):76-80. PMID: 7706076
Study Type : Human Study
[+]
Pubmed Data : Br J Clin Pharmacol. 2004 Jul;58(1):56-60. PMID: 15206993
Study Type : Human Study
Additional Links
Substances : Grapefruit
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Simvastatin, Statin Drugs
[+]
Pubmed Data : Hematol Oncol. 2009 Mar;27(1):17-22. PMID: 18668701
Study Type : Human Study
Additional Links
Diseases : Multiple Myeloma
Problem Substances : Simvastatin
[+]
Pubmed Data : Metabolism. 2000 Sep ;49(9):1234-8. PMID: 11016911
Study Type : Human Study
Additional Links
Diseases : Low Testosterone
Problem Substances : Simvastatin, Statin Drugs
Adverse Pharmacological Actions : Endocrine Disruptor
[+]
Pubmed Data : J Hepatol. 2011 Aug 31. Epub 2011 Aug 31. PMID: 21889469
Study Type : Human Study
[+]
Pubmed Data : Neurology. 2002 May 14 ;58(9):1333-7. PMID: 12011277
Study Type : Human Study
Additional Links
Adverse Pharmacological Actions : Neurotoxic
[+]
Pubmed Data : Neuro Endocrinol Lett. 2011 Sep 3 ;32(5):688-690. Epub 2011 Sep 3. PMID: 22167150
Study Type : Human Study
Additional Links
Problem Substances : Simvastatin, Statin Drugs
Adverse Pharmacological Actions : Neurotoxic
[+]
Pubmed Data : Cardiovasc Toxicol. 2010 Jun ;10(2):130-8. PMID: 20383667
Study Type : Human Study
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Cardiovasc Disord. 2017 05 18 ;17(1):127. Epub 2017 May 18. PMID: 28521773
Study Type : Human Study
Additional Links
Substances : Red Yeast Rice
Diseases : Dyslipidemias
Pharmacological Actions : Hypolipidemic
Additional Keywords : Natural Substances Versus Drugs
Problem Substances : Simvastatin, Statin Drugs
[+]
Pubmed Data : Minerva Gastroenterol Dietol. 1992 Jan-Mar;38(1):41-4. PMID: 1520752
Study Type : Human Study
Additional Links
Problem Substances : Pravastatin , Simvastatin, Statin Drugs
Adverse Pharmacological Actions : Hepatotoxic
[+]
Pubmed Data : Ann Pharmacother. 2009 Dec;43(12):2012-20. Epub 2009 Nov 17. PMID: 19920157
Study Type : Human Study
Additional Links
Problem Substances : Simvastatin
[+]
Pubmed Data : Eur J Immunol. 2008 Oct;38(10):2832-44. PMID: 18958884
Study Type : Human Study
Additional Links
Problem Substances : Simvastatin
[+]
Pubmed Data : Alzheimer Dis Assoc Disord. 2010 Jul-Sep;24(3):220-6. PMID: 20473136
Study Type : Human Study
Additional Links
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Simvastatin
Adverse Pharmacological Actions : Neurotoxic
[+]
Pubmed Data : Horm Metab Res. 1996 Apr ;28(4):193-8. PMID: 8740196
Study Type : Human Study
Additional Links
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Simvastatin
Adverse Pharmacological Actions : Endocrine Disruptor
[+]
Pubmed Data : Psychoneuroendocrinology. 2003 Feb ;28(2):181-94. PMID: 12510011
Study Type : Human Study
Additional Links
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Simvastatin
Adverse Pharmacological Actions : Endocrine Disruptor
[+]
Pubmed Data : N Z Med J. 1991 Nov 27 ;104(924):493-5. PMID: 1745460
Study Type : Human Study
Additional Links
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Simvastatin, Statin Drugs
[+]
Pubmed Data : Am J Med. 2004 Dec 1 ;117(11):823-9. PMID: 15589485
Study Type : Human Study
Additional Links
Problem Substances : Simvastatin, Statin Drugs
Adverse Pharmacological Actions : Neurotoxic
[+]
Pubmed Data : Eur J Clin Invest. 2002 Dec ;32(12):901-8. PMID: 12534449
Study Type : Human Study
Additional Links
Pharmacological Actions : Nitric Oxide Inhibitor
[+]
Pubmed Data : Int J Clin Pract. 2011 Nov ;65(11):1141-8. PMID: 21995692
Study Type : Human Study
Additional Links
Adverse Pharmacological Actions : Endocrine Disruptor: Insulin Resistance
[+]
Pubmed Data : J Pathol. 2006 Sep ;210(1):94-102. PMID: 16799920
Study Type : Human Study
Additional Links
Pharmacological Actions : Anticholesteremic Agents
Adverse Pharmacological Actions : Myotoxicity
[+]
Pubmed Data : Clin Pharmacol Ther. 2005 Jul;78(1):60-8. PMID: 16003294
Study Type : Human Study
[+]
Pubmed Data : J Clin Pharmacol. 1993 Mar;33(3):226-9. PMID: 8463436
Study Type : Human Study
Additional Links
Adverse Pharmacological Actions : Cytotoxic
[+]
Pubmed Data : Pharmacotherapy. 2003 Jul ;23(7):871-80. PMID: 12885101
Study Type : Human Study
Additional Links
Adverse Pharmacological Actions : Neurotoxic
[+]
Pubmed Data : Am J Cardiovasc Drugs. 2010 ;10(3):187-92. PMID: 20524720
Study Type : Human Study
Additional Links
Problem Substances : Simvastatin, Statin Drugs
Adverse Pharmacological Actions : Myotoxicity
[+]
Pubmed Data : Drug Saf. 2002 ;25(12):877-83. PMID: 12241128
Study Type : Human Study
Additional Links
Diseases : Oxidative Stress
Adverse Pharmacological Actions : Oxidant
[+]
Pubmed Data : Diabetes Care. 2012 Dec 17. Epub 2012 Dec 17. PMID: 23248196
Study Type : Human Study
Additional Links
Problem Substances : Atorvastatin, Simvastatin, Statin Drugs
Adverse Pharmacological Actions : Diabetogenic
[+]
Pubmed Data : J Trace Elem Med Biol. 2005;19(1):61-7. PMID: 16240674
Study Type : Human Study
[+]
Pubmed Data : Diabetes Care. 2009 Apr ;32(4):541-6. Epub 2008 Dec 29. PMID: 19114614
Study Type : Human Study
Additional Links
Additional Keywords : Sex Hormone-Binding Globulin
Problem Substances : Atorvastatin, Simvastatin, Statin Drugs
Adverse Pharmacological Actions : Endocrine Disruptor
[+]
Pubmed Data : Prostaglandins Leukot Essent Fatty Acids. 2004 Oct ;71(4):263-9. PMID: 15310527
Study Type : Human Study
Additional Links
Problem Substances : Simvastatin
[+]
Pubmed Data : Clin Ther. 1990 Sep-Oct;12(5):410-20. PMID: 2268863
Study Type : Human Study
Additional Links
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Lovastatin, Simvastatin, Statin Drugs
Adverse Pharmacological Actions : Endocrine Disruptor
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Physiol Res. 2016 Jul 15. Epub 2016 Jul 15. PMID: 27429121
Study Type : Animal Study, Human Study
Additional Links
Additional Keywords : Risk Factors
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Drug Investig. 2015 Dec 30. Epub 2015 Dec 30. PMID: 26718960
Study Type : Human Study
Additional Links
Additional Keywords : Increased Risk
Problem Substances : Simvastatin, Statin Drugs
Adverse Pharmacological Actions : Cardiotoxic
[+]
Pubmed Data : Ann Pharmacother. 2007 Jan;41(1):138-42. Epub 2007 Jan 2. PMID: 17200428
Study Type : Human Study
Additional Links
Problem Substances : Simvastatin, Statin Drugs
[+]
Pubmed Data : Biofactors. 2003;18(1-4):113-24. PMID: 14695926
Study Type : Human Study
[+]
Pubmed Data : Basic Clin Pharmacol Toxicol. 2006 Jan ;98(1):51-4. PMID: 16433891
Study Type : Human Study
Additional Links
Pharmacological Actions : Anticholesteremic Agents
[+]
Pubmed Data : Atherosclerosis. 2014 Jan ;232(1):204-10. Epub 2013 Nov 19. PMID: 24401239
Study Type : Human Study
[+]
Pubmed Data : Expert Opin Drug Saf. 2012 Jul ;11(4):543-9. Epub 2012 Apr 16. PMID: 22502740
Study Type : Human Study
Additional Links
Problem Substances : Simvastatin
Adverse Pharmacological Actions : Carcinogenic
[+]
Pubmed Data : Arzneimittelforschung. 1999 Apr;49(4):324-9. PMID: 10337451
Study Type : Human Study
[+]
Pubmed Data : BMJ. 2010;340:c2197. Epub 2010 May 20. PMID: 20488911
Study Type : Human Study
[+]
Pubmed Data : Gastroenterol Clin Biol. 1991 ;15(1):94-5. PMID: 2010080
Study Type : Human: Case Report
Additional Links
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Lovastatin, Simvastatin
Adverse Pharmacological Actions : Hepatotoxic
[+]
Pubmed Data : Gastroenterol Clin Biol. 1991 ;15(12):986-7. PMID: 1783261
Study Type : Human: Case Report
Additional Links
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Simvastatin
[+]
Pubmed Data : Rev Rhum Mal Osteoartic. 1992 Apr ;59(4):281-3. PMID: 1496277
Study Type : Human: Case Report
Additional Links
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Simvastatin
Adverse Pharmacological Actions : Cardiotoxic, Myotoxicity
[+]
Pubmed Data : J Intern Med. 1996 Dec ;240(6):403-4. PMID: 9010388
Study Type : Human: Case Report
Additional Links
Additional Keywords : Drug Synergy
Problem Substances : Fenofibrates, Gemfibrozil, Simvastatin
Adverse Pharmacological Actions : Myotoxicity
[+]
Pubmed Data : Clin Exp Dermatol. 1994 Jan ;19(1):88-9. PMID: 8313650
Study Type : Human: Case Report
Additional Links
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Simvastatin
[+]
Pubmed Data : Clin Exp Dermatol. 2003 Sep ;28(5):558-9. PMID: 12950356
Study Type : Human: Case Report
Additional Links
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Simvastatin
[+]
Pubmed Data : Heart Vessels. 2003 Jul ;18(3):157-9. PMID: 12955433
Study Type : Human: Case Report
Additional Links
Problem Substances : Simvastatin, Statin Drugs
Adverse Pharmacological Actions : Cardiotoxic
[+]
Pubmed Data : J Clin Gastroenterol. 2006 Sep ;40(8):757-61. PMID: 16940892
Study Type : Human: Case Report
Additional Links
Problem Substances : Atorvastatin, Simvastatin
Adverse Pharmacological Actions : Hepatotoxic, Immunotoxic
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Isr Med Assoc J. 2011 Mar ;13(3):185-6. PMID: 21608343
Study Type : Human: Case Report
Additional Links
Problem Substances : Simvastatin, Statin Drugs
[+]
Pubmed Data : Curr Drug Saf. 2012 Feb ;7(1):33-4. PMID: 22663955
Study Type : Human: Case Report
Additional Links
Problem Substances : Simvastatin, Statin Drugs
[+]
Pubmed Data : Cutis. 1998 Oct ;62(4):197-8. PMID: 9798110
Study Type : Human: Case Report
Additional Links
Problem Substances : Simvastatin, Statin Drugs
[+]
Pubmed Data : Photodermatol Photoimmunol Photomed. 2002 Dec ;18(6):313-4. PMID: 12535029
Study Type : Human: Case Report
Additional Links
Problem Substances : Simvastatin
[+]
Pubmed Data : Clin Ther. 2010 May;32(5):909-14. PMID: 20685498
Study Type : Human: Case Report
Additional Links
Problem Substances : Danazol, Simvastatin
[+]
Pubmed Data : Tenn Med. 2000 Jun ;93(6):210-2. PMID: 10846948
Study Type : Human: Case Report
Additional Links
Diseases : Thyroid Cancer
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Simvastatin, Statin Drugs
[+]
Pubmed Data : Eur J Intern Med. 2006 Oct ;17(6):450. PMID: 16962959
Study Type : Human: Case Report
Additional Links
Problem Substances : Simvastatin, Statin Drugs
[+]
Pubmed Data : Am J Med. 2000 Mar ;108(4):351-2. PMID: 11014734
Study Type : Human: Case Report
Additional Links
Problem Substances : Simvastatin
Adverse Pharmacological Actions : Myotoxicity
[+]
Pubmed Data : J Intern Med. 1996 Apr ;239(4):361-3. PMID: 8774391
Study Type : Human: Case Report
Additional Links
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Simvastatin, Statin Drugs
[+]
Pubmed Data : Dermatology. 2004 ;208(3):276-7. PMID: 15118389
Study Type : Human: Case Report
Additional Links
Problem Substances : Simvastatin, Statin Drugs
Adverse Pharmacological Actions : Immunotoxic
[+]
Pubmed Data : Clin Neuropharmacol. 2009 Nov-Dec;32(6):348-9. PMID: 19952877
Study Type : Human: Case Report
Additional Links
Problem Substances : Simvastatin
Adverse Pharmacological Actions : Myotoxicity
[+]
Pubmed Data : Ann Pharmacother. 2001 Oct ;35(10):1292. PMID: 11675864
Study Type : Human: Case Report
Additional Links
Pharmacological Actions : Antihypertensive Agents
Problem Substances : Metoprolol, Simvastatin
[+]
Pubmed Data : Ann Pharmacother. 2002 Feb ;36(2):275-9. PMID: 11847949
Study Type : Human: Case Report
Additional Links
Problem Substances : Fenofibrates, Simvastatin
[+]
Pubmed Data : J Neurol Neurosurg Psychiatry. 1995 May ;58(5):625-8. PMID: 7745415
Study Type : Human: Case Report
Additional Links
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Lovastatin, Simvastatin
Adverse Pharmacological Actions : Neurotoxic
[+]
Pubmed Data : South Med J. 1998 Jul ;91(7):667-8. PMID: 9671841
Study Type : Human: Case Report
Additional Links
Pharmacological Actions : Anticholesteremic Agents
Adverse Pharmacological Actions : Neurotoxic
[+]
Pubmed Data : Ned Tijdschr Geneeskd. 1993 Jun 26 ;137(26):1312-5. PMID: 8345888
Study Type : Human: Case Report
Additional Links
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Simvastatin, Statin Drugs
Adverse Pharmacological Actions : Neurotoxic
[+]
Pubmed Data : Cardiology. 2000 ;94(2):127-8. PMID: 11173785
Study Type : Human: Case Report
[+]
Pubmed Data : South Med J. 2005 Aug ;98(8):827-9. PMID: 16144183
Study Type : Human: Case Report
Additional Links
Problem Substances : Simvastatin, Statin Drugs
[+]
Pubmed Data : Ann Pharmacother. 2010 Dec ;44(12):1994-7. Epub 2010 Nov 2. PMID: 21045169
Study Type : Human: Case Report
Additional Links
Problem Substances : Simvastatin, Statin Drugs
Adverse Pharmacological Actions : Myotoxicity
[+]
Pubmed Data : Heart. 2004 Jan ;90(1):e3. PMID: 14676266
Study Type : Human: Case Report
Additional Links
Problem Substances : Simvastatin, Statin Drugs
Adverse Pharmacological Actions : Myotoxicity
[+]
Pubmed Data : Rev Neurol. 2003 Nov 16-30;37(10):934-6. PMID: 14634922
Study Type : Human: Case Report
Additional Links
Diseases : Polymyositis
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Simvastatin
[+]
Pubmed Data : Recenti Prog Med. 1991 Apr ;82(4):233-5. PMID: 1857844
Study Type : Human: Case Report
Additional Links
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Simvastatin, Statin Drugs
Adverse Pharmacological Actions : Hepatotoxic
[+]
Pubmed Data : J Cutan Med Surg. 2010 Sep-Oct;14(5):207-11. PMID: 20868617
Study Type : Human: Case Report
Additional Links
Problem Substances : Simvastatin, Statin Drugs
[+]
Pubmed Data : Ned Tijdschr Geneeskd. 1996 Apr 13 ;140(15):846-8. PMID: 8668280
Study Type : Human: Case Report
Additional Links
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Simvastatin, Statin Drugs
[+]
Pubmed Data : Int J Cardiol. 2007 Jul 31 ;119(3):374-6. Epub 2006 Nov 13. PMID: 17098308
Study Type : Human: Case Report
Additional Links
Problem Substances : Simvastatin, Statin Drugs
Adverse Pharmacological Actions : Endocrine Disruptor: Thyroid
[+]
Pubmed Data : Pharmacotherapy. 2006 Mar ;26(3):414-22. PMID: 16503723
Study Type : Human: Case Report
Additional Links
Diseases : Pancreatitis
Problem Substances : Simvastatin, Statin Drugs
[+]
Pubmed Data : Pharmacotherapy. 2008 Sep ;28(9):1188-93. PMID: 18752389
Study Type : Human: Case Report
Additional Links
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Simvastatin, Statin Drugs
Adverse Pharmacological Actions : Hepatotoxic
[+]
Pubmed Data : Ann Pharmacother. 2006 Oct ;40(10):1880-3. Epub 2006 Aug 29. PMID: 16940411
Study Type : Human: Case Report
Additional Links
Problem Substances : Simvastatin
Adverse Pharmacological Actions : Neurotoxic
[+]
Pubmed Data : Hautarzt. 2009 Jun ;60(6):489-93. PMID: 18853127
Study Type : Human: Case Report
Additional Links
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Simvastatin
[+]
Pubmed Data : Clin Pharmacol Ther. 2002 Oct ;72(4):461-4. PMID: 12386648
Study Type : Human: Case Report
[+]
Pubmed Data : Ann Dermatol Venereol. 2003 Feb ;130(2 Pt 1):187-90. PMID: 12671581
Study Type : Human: Case Report
Additional Links
Problem Substances : Simvastatin, Statin Drugs
[+]
Pubmed Data : South Med J. 1998 Sep ;91(9):873-4. PMID: 9743064
Study Type : Human: Case Report
Additional Links
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Simvastatin
[+]
Pubmed Data : Tenn Med. 2000 Jan ;93(1):21-2. PMID: 10628262
Study Type : Human: Case Report
Additional Links
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Simvastatin
[+]
Pubmed Data : Arq Neuropsiquiatr. 2004 Jun ;62(2B):540-2. Epub 2004 Jul 20. PMID: 15273860
Study Type : Human: Case Report
Additional Links
Problem Substances : Simvastatin, Statin Drugs
Adverse Pharmacological Actions : Neurotoxic
[+]
Pubmed Data : Blood Purif. 2008 ;26(4):394-8. Epub 2008 Jul 1. PMID: 18594138
Study Type : Human: Case Report
Additional Links
Problem Substances : Simvastatin
Adverse Pharmacological Actions : Nephrotoxic
[+]
Pubmed Data : Emerg Med J. 2008 May ;25(5):305-6. PMID: 18434476
Study Type : Human: Case Report
Additional Links
Problem Substances : Simvastatin, Statin Drugs
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : JOP. 2004 Nov ;5(6):502-4. Epub 2004 Nov 10. PMID: 15536291
Study Type : Human: Case Report
[+]
Pubmed Data : J Neurol Sci. 2003 Apr 15 ;208(1-2):105-8. PMID: 12639733
Study Type : Human: Case Report
Additional Links
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Simvastatin
Adverse Pharmacological Actions : Neurotoxic
[+]
Pubmed Data : Neuromuscul Disord. 2007 Feb ;17(2):194-200. Epub 2007 Jan 22. PMID: 17241784
Study Type : Human: Case Report
[+]
Pubmed Data : Int J Clin Pharmacol Ther. 2005 Nov ;43(11):543-5. PMID: 16300170
Study Type : Human: Case Report
Additional Links
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Simvastatin
Adverse Pharmacological Actions : Myotoxicity, Nephrotoxic
[+]
Pubmed Data : Medicine (Baltimore). 2006 Mar ;85(2):82-5. PMID: 16609346
Study Type : Human: Case Report
Additional Links
Problem Substances : Pravastatin , Simvastatin, Statin Drugs
[+]
Pubmed Data : J Med Assoc Thai. 2011 Feb ;94(2):256-8. PMID: 21534375
Study Type : Human: Case Report
Additional Links
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Simvastatin, Statin Drugs
[+]
Pubmed Data : APMIS. 2005 Sep ;113(9):635-7. PMID: 16218940
Study Type : Human: Case Report
Additional Links
Problem Substances : Simvastatin
[+]
Pubmed Data : Neurology. 2004 Feb 24 ;62(4):670. PMID: 14981197
Study Type : Human: Case Report
Additional Links
Substances : Grapefruit
Pharmacological Actions : Anticholesteremic Agents, Enzyme Inhibitors
Problem Substances : Simvastatin
[+]
Pubmed Data : Eur Respir J. 2002 Mar ;19(3):577-80. PMID: 11936540
Study Type : Human: Case Report
Additional Links
Problem Substances : Simvastatin, Statin Drugs
[+]
Pubmed Data : Wien Klin Wochenschr. 2002 Nov 30 ;114(21-22):943-4. PMID: 12528328
Study Type : Human: Case Report
Additional Links
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Atorvastatin, Pravastatin , Simvastatin
[+]
Pubmed Data : Clin Exp Dermatol. 2007 Sep ;32(5):589-91. PMID: 17692061
Study Type : Human: Case Report
Additional Links
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Simvastatin, Statin Drugs
[+]
Pubmed Data : Int J Rheum Dis. 2010 Aug ;13(3):e29-31. PMID: 20704607
Study Type : Human: Case Report
Additional Links
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Simvastatin, Statin Drugs
Adverse Pharmacological Actions : Immunosuppressive
[+]
Pubmed Data : J Clin Psychiatry. 2010 Mar ;71(3):359. PMID: 20331937
Study Type : Human: Case Report
Additional Links
Problem Substances : Simvastatin, Statin Drugs
[+]
Pubmed Data : Am J Cardiol. 2007 Jul 1 ;100(1):152-3. Epub 2007 May 21. PMID: 17599460
Study Type : Human: Case Report
Additional Links
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Simvastatin, Statin Drugs
[+]
Pubmed Data : J Dtsch Dermatol Ges. 2011 Jan ;9(1):54-5. Epub 2010 Oct 6. PMID: 21040470
Study Type : Human: Case Report
Additional Links
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Simvastatin
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Med Case Rep. 2016 Apr 5 ;10:83. Epub 2016 Apr 5. PMID: 27048383
Study Type : Human: Case Report
Additional Links
Problem Substances : Simvastatin, Statin Drugs
[+]
Pubmed Data : Gastroenterol Clin Biol. 1991 ;15(12):986. PMID: 1783260
Study Type : Human: Case Report
Additional Links
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Simvastatin
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Postgrad Med J. 2002 May ;78(919):286-7. PMID: 12151572
Study Type : Human: Case Report
Additional Links
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Simvastatin, Statin Drugs
Adverse Pharmacological Actions : Inflammatory
[+]
Pubmed Data : Dermatitis. 2010 Aug ;21(4):223-4. PMID: 20646678
Study Type : Human: Case Report
Additional Links
Problem Substances : Simvastatin
[+]
Pubmed Data : Cells Tissues Organs. 2020 May 5:1-19. Epub 2020 May 5. PMID: 32369804
Study Type : Animal Study
Additional Links
Substances : Ginkgo biloba
Pharmacological Actions : Antioxidants
Problem Substances : Simvastatin
[+]
Pubmed Data : Food Funct. 2015 Mar ;6(3):780-7. PMID: 25579987
Study Type : Animal Study
Additional Links
Diseases : Hyperlipidemia
Problem Substances : Simvastatin
[+]
Pubmed Data : Naunyn Schmiedebergs Arch Pharmacol. 2017 Feb ;390(2):215-223. Epub 2016 Dec 2. PMID: 27913825
Study Type : Animal Study
Additional Links
Substances : Beta-Caryophyllene
Additional Keywords : Natural Substances Versus Drugs
Problem Substances : Simvastatin, Statin Drugs
[+]
Pubmed Data : J Pharmacol Exp Ther. 2005 Feb ;312(2):786-93. Epub 2004 Sep 9. PMID: 15358814
Study Type : Animal Study
Additional Links
Problem Substances : Simvastatin
[+]
Pubmed Data : Aquat Toxicol. 2016 May ;174:1-9. Epub 2016 Feb 6. PMID: 26896816
Study Type : Environmental
Additional Links
Problem Substances : Simvastatin, Statin Drugs
[+]
Pubmed Data : Toxicol Appl Pharmacol. 2019 02 15 ;365:112-123. Epub 2019 Jan 11. PMID: 30639414
Study Type : Animal Study
[+]
Pubmed Data : Cell Mol Life Sci. 2006 Oct;63(19-20):2415-25. PMID: 17013560
Study Type : Animal Study
[+]
Pubmed Data : J Cardiovasc Pharmacol. 2000 Feb ;35(2):256-62. PMID: 10672858
Study Type : Animal Study
Additional Links
Additional Keywords : Lipophilic Stains
Adverse Pharmacological Actions : Cardiotoxic
[+]
Pubmed Data : Exp Eye Res. 1991 Aug ;53(2):179-86. PMID: 1915674
Study Type : Animal Study
Additional Links
[+]
Pubmed Data : Biosci Rep. 2010 Feb;30(1):41-50. Epub 2009 Oct 6. PMID: 19228123
Study Type : Animal Study
Additional Links
Problem Substances : Simvastatin, Statin Drugs
Adverse Pharmacological Actions : Myotoxicity
[+]
Pubmed Data : Eur J Pharmacol. 2011 Nov 12. Epub 2011 Nov 12. PMID: 22115894
Study Type : Animal Study
Additional Links
Problem Substances : Atorvastatin, Simvastatin, Statin Drugs
Adverse Pharmacological Actions : Anxiogenic
[+]
Pubmed Data : Mol Ther. 2015 Jul ;23(7):1160-8. Epub 2015 Apr 21. PMID: 25896249
Study Type : Animal Study
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Toxics. 2021 Feb 26 ;9(3). Epub 2021 Feb 26. PMID: 33652851
Study Type : Animal Study
Additional Links
Additional Keywords : Synergistic Toxicity
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Physiol. 2009 Jan 15 ;587(Pt 1):219-30. Epub 2008 Nov 10. PMID: 19001041
Study Type : Animal Study
Additional Links
Additional Keywords : Gene Expression
Problem Substances : Simvastatin, Statin Drugs
[+]
Pubmed Data : Physiol Res. 2007;56 Suppl 2:S49-54. Epub 2007 Sep 5. PMID: 17824807
Study Type : Animal Study
[+]
Pubmed Data : Folia Neuropathol. 2010;48(1):49-56. PMID: 20383811
Study Type : Animal Study
Additional Links
Diseases : Neuropathies
Problem Substances : Simvastatin
Adverse Pharmacological Actions : Neurotoxic
[+]
Pubmed Data : Glia. 2007 Jan 15 ;55(2):130-43. PMID: 17078030
Study Type : Animal Study
Additional Links
Problem Substances : Simvastatin, Statin Drugs
Adverse Pharmacological Actions : Neurotoxic
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2018 ;2018:7617312. Epub 2018 Nov 4. PMID: 30519583
Study Type : Animal Study
Additional Links
Additional Keywords : Increased Risk
Problem Substances : Simvastatin
[+]
Pubmed Data : Br J Pharmacol. 1995 Sep ;116(2):1894-8. PMID: 8528576
Study Type : Animal Study
[+]
Pubmed Data : Pharm Res. 1994 Feb ;11(2):305-11. PMID: 8165193
Study Type : Animal Study
Additional Links
Problem Substances : Lovastatin, Simvastatin, Statin Drugs
Adverse Pharmacological Actions : Neurotoxic
[+]
Pubmed Data : J Pharmacol Exp Ther. 1991 Jun;257(3):1225-35. PMID: 1904494
Study Type : Animal Study
[+]
Pubmed Data : Am J Physiol. 1997 Jan ;272(1 Pt 1):L106-14. PMID: 9038909
Study Type : Animal Study
Additional Links
Diseases : Lung Diseases
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Lovastatin, Simvastatin
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Pathol. 2009 Apr 6. PMID: 19349355
Study Type : Animal Study
Additional Links
Problem Substances : Simvastatin, Statin Drugs
Adverse Pharmacological Actions : Neurotoxic
[+]
Pubmed Data : Eur J Pharmacol. 1994 Aug 3 ;270(4):365-9. PMID: 7805787
Study Type : Animal Study
Additional Links
Adverse Pharmacological Actions : Hepatotoxic
[+]
Pubmed Data : Exp Neurol. 2008 Nov ;214(1):78-86. Epub 2008 Aug 5. PMID: 18722369
Study Type : Animal Study
[+]
Pubmed Data : Clin Exp Immunol. 2010 Aug ;161(2):298-305. Epub 2010 May 18. PMID: 20491794
Study Type : Animal Study
Additional Links
Problem Substances : Simvastatin
Adverse Pharmacological Actions : Immunosuppressive
[+]
Pubmed Data : Toxicol Pathol. 1991 ;19(3):197-205. PMID: 1780636
Study Type : Animal Study
Additional Links
Diseases : Thyroid Cancer
[+]
Pubmed Data : J Food Biochem. 2020 Feb 3:e13160. Epub 2020 Feb 3. PMID: 32010989
Study Type : Animal Study
Additional Links
Substances : Sage
Pharmacological Actions : Hypolipidemic
Problem Substances : Simvastatin
[+]
Pubmed Data : Immunology. 2007 Mar;120(3):315-24. Epub 2006 Nov 28. PMID: 17140403
Study Type : Animal Study
Additional Links
Problem Substances : Simvastatin, Statin Drugs
[+]
Pubmed Data : 3 Biotech. 2020 Apr ;10(4):149. Epub 2020 Mar 2. PMID: 32181111
Study Type : In Vitro Study
Additional Links
Substances : Sesamol
Pharmacological Actions : Pancreato Protective Agents
Problem Substances : Simvastatin
[+]
Pubmed Data : Free Radic Biol Med. 2011 Oct 25. Epub 2011 Oct 25. PMID: 22080086
Study Type : In Vitro Study
Additional Links
Problem Substances : Simvastatin
Adverse Pharmacological Actions : Myotoxicity
[+]
Pubmed Data : Phytother Res. 2019 Dec 10. Epub 2019 Dec 10. PMID: 31823428
Study Type : In Vitro Study
Additional Links
Substances : Astragaloside
Pharmacological Actions : Anti-Apoptotic
Problem Substances : Simvastatin
[+]
Pubmed Data : Pharmacotherapy. 2003 Dec ;23(12):1663-7. PMID: 14695047
Study Type : Review
Additional Links
Adverse Pharmacological Actions : Neurotoxic
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : JOP. 2005 Jul ;6(4):380; author reply 380-1. Epub 2005 Jul 8. PMID: 16006693
Study Type : Review
Additional Links
Problem Substances : Simvastatin, Statin Drugs
[+]
Pubmed Data : J Toxicol Sci. 2007 Feb ;32(1):57-67. PMID: 17327694
Study Type : In Vitro Study
Additional Links
Problem Substances : Simvastatin
Adverse Pharmacological Actions : Endocrine Disruptor
[+]
Pubmed Data : Eur J Pharmacol. 2011 Oct 25. Epub 2011 Oct 25. PMID: 22040920
Study Type : In Vitro Study
Additional Links
Problem Substances : Simvastatin
Adverse Pharmacological Actions : Cytotoxic
[+]
Pubmed Data : Brain Res. 2000 Mar 17 ;859(1):169-72. PMID: 10720627
Study Type : In Vitro Study
Additional Links
Problem Substances : Simvastatin
Adverse Pharmacological Actions : Neurotoxic
[+]
Pubmed Data : Neurosci Lett. 1996 Dec 6 ;220(1):21-4. PMID: 8977139
Study Type : In Vitro Study
Additional Links
Pharmacological Actions : Antiproliferative , Enzyme Inhibitors
Problem Substances : Simvastatin
Adverse Pharmacological Actions : Neurotoxic
[+]
Pubmed Data : J Neurosci Res. 2010 Nov 15 ;88(15):3361-75. PMID: 20857509
Study Type : In Vitro Study
Additional Links
Problem Substances : Simvastatin
Adverse Pharmacological Actions : Neurotoxic
[+]
Pubmed Data : J Pharmacol Exp Ther. 2008 Oct;327(1):130-6. Epub 2008 Jul 1. PMID: 18593956
Study Type : In Vitro Study
Additional Links
Problem Substances : Simvastatin, Statin Drugs
[+]
Pubmed Data : Biol Reprod. 2011 Sep 21. Epub 2011 Sep 21. PMID: 21918126
Study Type : In Vitro Study
Additional Links
Problem Substances : Simvastatin
Adverse Pharmacological Actions : Endocrine Disruptor: Ovary
[+]
Pubmed Data : J Steroid Biochem Mol Biol. 1991 Apr ;38(4):465-8. PMID: 2031860
Study Type : In Vitro Study
Additional Links
Problem Substances : Simvastatin, Statin Drugs
Adverse Pharmacological Actions : Endocrine Disruptor, Teratogenic
[+]
Pubmed Data : Acta Otolaryngol. 2009 Feb ;129(2):166-74. PMID: 18607908
Study Type : In Vitro Study
Additional Links
Problem Substances : Simvastatin, Statin Drugs
Adverse Pharmacological Actions : Neurotoxic
[+]
Pubmed Data : Biochim Biophys Acta. 2011 Aug 4. Epub 2011 Aug 4. PMID: 21839782
Study Type : In Vitro Study
Additional Links
Problem Substances : Simvastatin
Adverse Pharmacological Actions : Myotoxicity
[+]
Pubmed Data : Psychiatry Res. 2005 Feb 28 ;133(2-3):197-203. PMID: 15740995
Study Type : Review
Additional Links
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Simvastatin
[+]
Pubmed Data : Toxicology. 2006 Feb 15 ;219(1-3):124-32. Epub 2005 Dec 15. PMID: 16343726
Study Type : Review
Additional Links
Problem Substances : Lovastatin, Simvastatin, Statin Drugs
Adverse Pharmacological Actions : Cytotoxic
[+]
Pubmed Data : Biol Reprod. 2005 Mar ;72(3):538-45. Epub 2004 Sep 22. PMID: 15385411
Study Type : In Vitro Study
Additional Links
Problem Substances : Lovastatin, Simvastatin, Statin Drugs
Adverse Pharmacological Actions : Apoptotic, Endocrine Disruptor: Ovary
[+]
Pubmed Data : Toxicol Appl Pharmacol. 1995 Mar ;131(1):163-74. PMID: 7878672
Study Type : In Vitro Study
Additional Links
Pharmacological Actions : Anticholesteremic Agents
Adverse Pharmacological Actions : Myotoxicity
[+]
Pubmed Data : Exp Eye Res. 1990 Jan ;50(1):65-78. PMID: 2307197
Study Type : Review
Additional Links
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Lovastatin, Simvastatin, Statin Drugs
Adverse Pharmacological Actions : Cataractogenic
[+]
Pubmed Data : Am J Physiol. 1991 Nov ;261(5 Pt 1):C780-6. PMID: 1659206
Study Type : In Vitro Study
[+]
Pubmed Data : Neurology. 2004 Dec 14 ;63(11):2188. PMID: 15596782
Study Type : Review
Additional Links
[+]
Pubmed Data : Biochem Pharmacol. 2010 Apr 15 ;79(8):1200-9. Epub 2009 Dec 14. PMID: 20018177
Study Type : In Vitro Study
Additional Links
Problem Substances : Simvastatin, Statin Drugs
Adverse Pharmacological Actions : Myotoxicity
[+]
Pubmed Data : Biochem Biophys Res Commun. 2005 Apr 15 ;329(3):1067-75. PMID: 15752763
Study Type : In Vitro Study
Additional Links
Problem Substances : Simvastatin
Adverse Pharmacological Actions : Myotoxicity
[+]
Pubmed Data : Glia. 2007 Jan 1 ;55(1):1-12. PMID: 16998865
Study Type : In Vitro Study
Additional Links
Problem Substances : Atorvastatin, Simvastatin, Statin Drugs
Adverse Pharmacological Actions : Neurotoxic
[+]
Pubmed Data : Exp Neurol. 2009 Jan;215(1):41-7. Epub 2008 Sep 27. PMID: 18929563
Study Type : In Vitro Study
Additional Links
Problem Substances : Simvastatin

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Over 30 billion dollars worth of this drug is sold annually and yet it may be benefiting no one. In fact, there are over 300 adverse effects associated with its use, not the least of which is the weakening of the heart muscle. In order to cover-up the symptoms of statin-induced muscle damage new "diseases" have been coined, including polymyalgia rheumatica.
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