Sorbitol

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9 Diseases Researched for Sorbitol
NameACCKFocus
Diarrhea220Locked
Cognitive Decline/Dysfunction110Locked
Diabetes Mellitus: Type 1: Prevention110Locked
Gastrointestinal Cancer110Locked
Gastrointestinal Diseases110Locked
Irritable Bowel Syndrome110Locked
Acid-Base Imbalance13Locked
Hypernatremia13Locked
Water-Electrolyte Imbalance13Locked
1 Adverse Pharmacological Actions Researched for Sorbitol
NameACCKFocus
Neurotoxic110Locked

View the Evidence:
6 Abstracts with Sorbitol Research

[+]

Association between consumption of low- and no-calorie artificial sweeteners and cognitive decline.Oct 06, 2025

Pubmed Data : Neurology. 2025 Oct 7 ;105(7):e214023. Epub 2025 Sep 3. PMID: 40902134
Article Published Date : Oct 06, 2025
Study Type : Human Study
Additional Links
Diseases : Cognitive Decline/Dysfunction
Additional Keywords : Increased Risk
Problem Substances : Acesulfame potassium , Artificial Sweeteners, Aspartame, Sorbitol
Adverse Pharmacological Actions : Neurotoxic
[+]

Sorbitol intolerance associated wtih abdominal pain, bloating and diarrhea may be an under reported phenomenon. Sep 01, 1985

Pubmed Data : Am J Gastroenterol. 1985 Sep;80(9):678-81. PMID: 4036946
Article Published Date : Sep 01, 1985
Study Type : Human Study
Additional Links
Diseases : Diarrhea, Gastrointestinal Diseases, Irritable Bowel Syndrome
Problem Substances : Sorbitol
[+]

Sorbitol intolerance may be at the root of "functional" gastointestinal complaints.Jan 01, 1983

Pubmed Data : Gastroenterology. 1983 Jan;84(1):30-3. PMID: 6847853
Article Published Date : Jan 01, 1983
Study Type : Human Study
Additional Links
Diseases : Diarrhea, Gastrointestinal Cancer
Problem Substances : Sorbitol
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Sorbitol production and accumulation may be associated with pathological changes in diabetics.May 01, 2004

Pubmed Data : J Exp Zool A Comp Exp Biol. 2004 May 1;301(5):439-48. PMID: 15114651
Article Published Date : May 01, 2004
Study Type : Human Study
Additional Links
Diseases : Diabetes Mellitus: Type 1: Prevention
Problem Substances : Sorbitol
[+]

Severe electrolyte and acid-base disturbances have been reported after administration of sorbitol.Jan 01, 1997

Pubmed Data : J Neurosurg Anesthesiol. 1997 Jan;9(1):17-20. PMID: 9016435
Article Published Date : Jan 01, 1997
Study Type : Human: Case Report
Additional Links
Diseases : Acid-Base Imbalance, Water-Electrolyte Imbalance
Problem Substances : Sorbitol
[+]

Sorbitol used as an osmotic cathartic has caused severe hypernatremia (elevation of sodium in the blood) in children.May 01, 1991

Pubmed Data : Am J Kidney Dis. 1991 May;17(5):581-4. PMID: 2024660
Article Published Date : May 01, 1991
Study Type : Human: Case Report
Additional Links
Diseases : Hypernatremia
Problem Substances : Sorbitol

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