Pubmed Data : J Pediatr Gastroenterol Nutr. 2018 Mar ;66(3):466-470. PMID: 29077645
Article Published Date : Feb 28, 2018
Study Type : Human Study
Additional Links
Problem Substances : Acesulfame potassium , Sucralose (aka Splenda)
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35 Abstracts with Sucralose (aka Splenda) Research
Pubmed Data : Nature. 2014 Sep 17. Epub 2014 Sep 17. PMID: 25231862
Article Published Date : Sep 16, 2014
Study Type : Animal Study, Human Study
Additional Links
Diseases : Diabetes Mellitus: Type 2, Diabetes Mellitus: Type 2: Prevention, Dysbiosis, Insulin Resistance, Metabolic Syndrome X
Problem Substances : Artificial Sweeteners, Artificially Sweetened Beverages, Aspartame, Saccharin, Sucralose (aka Splenda)
Pubmed Data : Am J Clin Nutr. 2017 Feb 22. Epub 2017 Feb 22. PMID: 28228424
Article Published Date : Feb 21, 2017
Study Type : Human Study
Additional Links
Problem Substances : Sucralose (aka Splenda)
Pubmed Data : J Toxicol Environ Health A. 2015 ;78(16):1029-32. Epub 2015 Aug 12. PMID: 26267522
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Problem Substances : Acesulfame potassium , Artificial Sweeteners, Saccharin, Sucralose (aka Splenda)
Pubmed Data : Diabetes Care. 2013 Apr 30. Epub 2013 Apr 30. PMID: 23633524
Article Published Date : Apr 29, 2013
Study Type : Human Study
Additional Links
Problem Substances : Sucralose (aka Splenda)
Adverse Pharmacological Actions : Endocrine Disruptor: Insulin Resistance
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2022 Nov 24 ;14(23). Epub 2022 Nov 24. PMID: 36501030
Article Published Date : Nov 23, 2022
Study Type : Human Study
Additional Links
Diseases : Insulin Resistance, Pregnancy Complications
Problem Substances : Aspartame, Sucralose (aka Splenda)
Pubmed Data : Sci Total Environ. 2022 Jul 10 ;829:154689. Epub 2022 Mar 18. PMID: 35314215
Article Published Date : Jul 09, 2022
Study Type : Animal Study
Additional Links
Diseases : Oxidative Stress, Prenatal Chemical Exposures
Problem Substances : Artificial Sweeteners, Sucralose (aka Splenda)
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Coll Physicians Surg Pak. 2019 Sep ;29(9):848-851. PMID: 31455480
Article Published Date : Aug 31, 2019
Study Type : Animal Study
Additional Links
Diseases : Chemically-Induced Liver Damage, Fatty Liver
Problem Substances : Aspartame, Sucralose (aka Splenda)
Pubmed Data : Arch Oral Biol. 2013 Sep ;58(9):1116-22. Epub 2013 Apr 28. PMID: 23631998
Article Published Date : Aug 31, 2013
Study Type : Animal Study
Additional Links
Diseases : Dental Caries
Pubmed Data : Morphologie. 2018 Aug 2. Epub 2018 Aug 2. PMID: 30078469
Article Published Date : Aug 01, 2018
Study Type : Animal Study
Additional Links
Diseases : Chemically-Induced Liver Damage
Problem Substances : Sucralose (aka Splenda)
Adverse Pharmacological Actions : Hepatotoxic
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Gut Microbes. 2023 ;15(1):2157698. PMID: 36524841
Article Published Date : Dec 31, 2022
Study Type : Animal Study
Additional Links
Diseases : Antibiotic Toxicity , Bacterial Infections: Resistance/Biofilm Formation, Infection: Antibiotic Resistant
Additional Keywords : Antibiotic Resistance, Infection: Antibiotic Resistant
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2018 ;13(7):e0199080. Epub 2018 Jul 5. PMID: 29975731
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Diseases : Dysbiosis
Additional Keywords : Microbiota
Problem Substances : Acesulfame potassium , Artificial Sweeteners, Saccharin, Sucralose (aka Splenda)
Pubmed Data : Int J Occup Environ Health. 2016 Jan ;22(1):7-17. Epub 2016 Jan 29. PMID: 27078173
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Problem Substances : Sucralose (aka Splenda)
Adverse Pharmacological Actions : Carcinogenic
Pubmed Data : Food Chem Toxicol. 1990 Jun;28(6):449-55. PMID: 2210518
Article Published Date : Jun 01, 1990
Study Type : Animal Study
Additional Links
Problem Substances : Sucralose (aka Splenda)
Pubmed Data : Food Funct. 2021 Oct 4 ;12(19):9380-9390. Epub 2021 Oct 4. PMID: 34606537
Article Published Date : Oct 03, 2021
Study Type : Animal Study
Additional Links
Diseases : Ulcerative Colitis
Problem Substances : Artificial Sweeteners, Sucralose (aka Splenda)
Adverse Pharmacological Actions : Gastrotoxic
Pubmed Data : Food Chem Toxicol. 2000;38 Suppl 2:S71-89. PMID: 10882819
Article Published Date : Jan 01, 2000
Study Type : Animal Study
Additional Links
Problem Substances : Sucralose (aka Splenda)
Pubmed Data : PLoS One. 2014 ;9(4):e92771. Epub 2014 Apr 3. PMID: 24699280
Article Published Date : Dec 31, 2013
Study Type : Insect Study
Additional Links
Diseases : Lipid Peroxidation
Problem Substances : Sucralose (aka Splenda)
Adverse Pharmacological Actions : Neurotoxic
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Eur J Nutr. 2016 Dec 31. Epub 2016 Dec 31. PMID: 28040879
Article Published Date : Dec 30, 2016
Study Type : Animal Study
Additional Links
Problem Substances : Sucralose (aka Splenda)
Adverse Pharmacological Actions : Endocrine Disruptor: Thyroid, Neurotoxic
Pubmed Data : Cell Metab. 2016 Jul 12 ;24(1):75-90. PMID: 27411010
Article Published Date : Jul 11, 2016
Study Type : Animal Study
Additional Links
Diseases : Eating Disorders
Problem Substances : Sucralose (aka Splenda)
Pubmed Data : Food Chem Toxicol. 2000;38 Suppl 2:S53-69. PMID: 10882818
Article Published Date : Aug 01, 2005
Study Type : Animal Study
Additional Links
Diseases : Immune Disorders: Low Immune Function
Problem Substances : Sucralose (aka Splenda)
Pubmed Data : Chemosphere. 2012 Jan ;86(1):50-5. Epub 2011 Sep 28. PMID: 21955350
Article Published Date : Jan 01, 2012
Study Type : Animal Study
Additional Links
Additional Keywords : Environmental Pollutant, Environmental Toxicity
Problem Substances : Sucralose (aka Splenda)
Pubmed Data : J Toxicol Environ Health A. 2018 Aug 21:1-11. Epub 2018 Aug 21. PMID: 30130461
Article Published Date : Aug 20, 2018
Study Type : Animal Study
Additional Links
Additional Keywords : Bioaccumulation
Problem Substances : Sucralose (aka Splenda)
Pubmed Data : J Toxicol Environ Health A. 2008;71(21):1415-29. PMID: 18800291
Article Published Date : Jan 01, 2008
Study Type : Animal Study
Additional Links
Problem Substances : Sucralose (aka Splenda)
Pubmed Data : Brain Res. 2018 12 1 ;1700:181-189. Epub 2018 Sep 7. PMID: 30201258
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Problem Substances : Sucralose (aka Splenda)
Adverse Pharmacological Actions : Neurotoxic
Pubmed Data : Inflamm Bowel Dis. 2018 Mar 15. Epub 2018 Mar 15. PMID: 29554272
Article Published Date : Mar 14, 2018
Study Type : Animal Study
Additional Links
Diseases : Crohn's Disease, Dysbiosis
Problem Substances : Artificial Sweeteners, Sucralose (aka Splenda)
Pubmed Data : Proc Natl Acad Sci U S A. 2007 Sep 18 ;104(38):15075-80. Epub 2007 Aug 27. PMID: 17724332
Article Published Date : Sep 17, 2007
Study Type : Animal Study
Additional Links
Additional Keywords : Cephalic Phase Effect
Pubmed Data : Can J Gastroenterol. 2011 Sep ;25(9):511. PMID: 21912763
Article Published Date : Sep 01, 2011
Study Type : Review
Additional Links
Problem Substances : Sucralose (aka Splenda)
Adverse Pharmacological Actions : Inflammatory
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2018 Sep 25 ;23(10). Epub 2018 Sep 25. PMID: 30257473
Article Published Date : Sep 24, 2018
Study Type : In Vitro Study
Additional Links
Additional Keywords : Microbiome
Problem Substances : Acesulfame potassium , Artificial Sweeteners, Aspartame, Sucralose (aka Splenda)
Pubmed Data : World J Gastroenterol. 2012 Apr 21 ;18(15):1708-22. PMID: 22553395
Article Published Date : Apr 21, 2012
Study Type : Review
Additional Links
Problem Substances : Sucralose (aka Splenda)
Adverse Pharmacological Actions : Inflammatory
Pubmed Data : Chem Res Toxicol. 2019 Jun 17 ;32(6):1241-1249. Epub 2019 May 23. PMID: 31079450
Article Published Date : Jun 16, 2019
Study Type : In Vitro Study
Additional Links
Problem Substances : Electronic Cigarettes, Sucralose (aka Splenda)
Pubmed Data : Environ Sci Technol. 2011 Aug 31. Epub 2011 Aug 31. PMID: 21879743
Article Published Date : Aug 31, 2011
Study Type : Review
Additional Links
Problem Substances : Sucralose (aka Splenda)
Pubmed Data : Environ Sci Technol. 2011 Jan 14. [Epub ahead of print]. PMID: 21235203
Study Type : In Vitro Study
Additional Links
Problem Substances : Sucralose (aka Splenda)
Pubmed Data : Headache. 2006 Sep;46(8):1303-4. PMID: 16942478
Article Published Date : Sep 01, 2006
Study Type : Commentary
Additional Links
Diseases : Migraine Disorders
Problem Substances : Sucralose (aka Splenda)
Pubmed Data : Physiol Behav. 2016 Apr 14. Epub 2016 Apr 14. PMID: 27090230
Article Published Date : Apr 13, 2016
Study Type : Bacterial
Additional Links
Diseases : Dysbiosis, Metabolic Diseases
Additional Keywords : Microbiota, Risk Factors
Pubmed Data : Mutat Res. 2002 Aug 26;519(1-2):103-19. PMID: 12160896
Article Published Date : Aug 26, 2002
Study Type : In Vitro Study
Additional Links
Diseases : DNA damage
Sucralose (aka Splenda) Related Articles
Written by Sayer Ji, Founder
A review on the synthetic sweetener sucralose (marketed as Splenda), published in the journal Toxicology and Environmental Health, overturns widely held misconceptions about the purported safety of this ubiquitous artificial sweetener.
Written by Sayer Ji, Founder
Sugar and artificial sweeteners are so accessible, affordable and socially sanctioned, that few consider their habitual consumption to be a problem on the scale of say, addiction to cocaine. But if recent research is correct, their addictive potential could be even worse.
Written by Erin Chamerlik, MS
Is your yogurt damaging your health? Are these highly processed ingredients in your grocery store yogurt?
Written by Dr. Veronique Desaulniers
Avoid these sugar substitutes for breast cancer healing, prevention and a healthy, chemical-free lifestyle.
Written by GMI Reporter
FDA-approved artificial sweeteners and sport supplements have now been found to be toxic to digestive gut microbes, according to a new paper published in the journal Molecules
Written by Sayer Ji, Founder
Splenda is marketed as a no-calorie, no-guilt sugar substitute. Blood sugar stable, it “passes right through” the body, so it’s safe for diabetics AND you won’t gain weight! Are these claims masking the ugly truth about this chemical imposter? As mounting research shows, when it comes to our diet, there is no free lunch
Written by Tania Melkonian
While millions around the world consume foods and beverages sweetened with Splenda (sucralose) with abandon, an accumulating body of research indicates that this synthetic chemical is far from safe, may contribute to obesity and blood sugar disorders, and more recently has even been linked to leukemia in animal experiments.
Written by GreenMedInfo Research Group
You may think that sweet e-cig liquid is a safer alternative to cigarettes, but a hidden danger lurks within those enticing vapor clouds. Recent research reveals that sucralose, a common vaping sweetener, transforms into highly toxic dioxin when heated.
Written by Sayer Ji, Founder
I don’t know what’s worse: a product full of GMOs and chemically-derived additives that proudly lauds its healthfulness and humanitarian benefits, or, a manufacturer that blatantly hides the fact they are using GMO ingredients by keeping them off the label?
Written by Sayer Ji, Founder
So, you are looking to lose a few pounds, or keep them off. What better way to accomplish this feat than to eliminate both empty sugar calories and synthetic sweeteners, which studies show can generate excessive cravings for sweets and actually increase weight gain.
Written by Sayer Ji, Founder
A concerning new study finds that most of the breast milk samples tested contained artificial sweeteners. Why has this never been discovered until now and what are the implications to our most vulnerable populations?
Written by Sayer Ji & Tania Melkonian
Food has lost its story. Stripped of context, meaning, and reduced to its molecular composition, ancient recipes for health and joy long to be recovered
Written by Sayer Ji, Founder
In the first study of its kind, Splenda (sucralose) has been found to have potential neurotoxic properties that could explain why it causes abnormal behavioral changes in aquatic animals
Written by Sayer Ji, Founder
A newly published study is destined to reignite the decades old controversy about aspartame's safety, or lack thereof. Aspartame converts to formaldehyde and formic acid, which are highly toxic to the body, but the nervous system in particular.
Written by Sayer Ji, Founder
Promoted for decades as a "safe" sugar alternative, presumably to prevent or reduce symptoms of diabetes, Splenda (sucralose) has been found to have diabetes-promoting effects in human subjects.
Written by Sayer Ji, Founder
It is hard to imagine how anyone still consumes Splenda (sucralose), considering how damning the accumulating body of scientific evidence is showing that it is a SERIOUS threat to both human and environmental health. A new study adds GENOTOXICITY to the list of this chemical's many serious mechanisms of harm.
Written by Sayer Ji, Founder
A groundbreaking new study reveals that non-caloric artificial sweeteners (NAS) drive obesity- and diabetes-related changes in both mice and humans.
Written by Sayer Ji, Founder
Synthetic sweeteners have been linked to a wide range of health problems, with over 80 documented on the GreenMedInfo database, alone. The various mechanisms of their toxicity, however, have not yet been fully elucidated. A new study raises a disturbing possibility that these widely consumed chemicals are driving otherwise 'good bacteria' into developing potentially lethal antibiotic resistance through a gut-mediated process.
Written by GreenMedInfo Research Group
That diet soda you're sipping to cut calories? It might be doing more harm than good. Recent research suggests some of the most popular artificial sweeteners could be wreaking havoc on your health - from disrupting your gut bacteria to potentially increasing cancer risk.
Written by GreenMedInfo Research Group
In a world where artificial sweeteners promise guilt-free indulgence, new research suggests that the popular sugar substitute sucralose may be secretly sabotaging women's reproductive health, one follicle at a time