Titanium Nanoparticles

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12 Diseases Researched for Titanium Nanoparticles
NameACCKFocus
Titanium Toxicity69Locked
Chemically-Induced Liver Damage24Locked
Bone Diseases12Locked
Dysbiosis12Locked
Infertility: Male12Locked
Kidney Damage: Chemically-Induced12Locked
Low Testosterone12Locked
Osteoarthritis12Locked
Oxidative Stress12Locked
Testicular Injury: Chemical/Metal Induced12Locked
Gastric Cancer11Locked
Inflammation11Locked
3 Adverse Pharmacological Actions Researched for Titanium Nanoparticles
NameACCKFocus
Gastrotoxic12Locked
Carcinogenic11Locked
Inflammatory11Locked

View the Evidence:
23 Abstracts with Titanium Nanoparticles Research

[+]

Aged garlic extract was able to reduce titanium dioxide toxicity in male rats. Aug 21, 2016

Pubmed Data : Andrologia. 2016 Aug 22. Epub 2016 Aug 22. PMID: 27546106
Article Published Date : Aug 21, 2016
Study Type : Animal Study
Additional Links
Substances : Garlic: Aged
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants
Problem Substances : Titanium Nanoparticles
[+]

Ameliorative effects of thymoquinone on titanium dioxide nanoparticles induced acute toxicity.May 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Vet Sci Med. 2018 Jun ;6(1):16-21. Epub 2018 Feb 23. PMID: 30255073
Article Published Date : May 31, 2018
Study Type : Animal Study
Additional Links
Substances : Thymoquinone
Diseases : Titanium Toxicity
Pharmacological Actions : Antioxidants
Problem Substances : Titanium Dioxide, Titanium Nanoparticles
[+]

Curcumin has immunomodulatory effects on RANKL-stimulated osteoclastogenesis in vitro and titanium nanoparticle-induced bone loss in vivo.Dec 16, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cell Mol Med. 2019 Dec 17. Epub 2019 Dec 17. PMID: 31845532
Article Published Date : Dec 16, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Bone Diseases, Osteoarthritis
Pharmacological Actions : Osteoprotective
Problem Substances : Titanium Nanoparticles
[+]

Ginkgo biloba extract reverses the renal effects of titanium dioxide nanoparticles in adult male rats.Dec 31, 2015

Pubmed Data : Biochem Res Int. 2016 ;2016:5781579. Epub 2016 Mar 3. PMID: 27042354
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Ginkgo biloba
Diseases : Kidney Damage: Chemically-Induced
Pharmacological Actions : Renoprotective
Additional Keywords : Plant Extracts
Problem Substances : Titanium Dioxide, Titanium Nanoparticles
[+]

Grape seed proanthocyanidin extract mitigates titanium dioxide nanoparticle-induced hepatotoxicity.Nov 06, 2019

Pubmed Data : Biol Trace Elem Res. 2019 Nov 7. Epub 2019 Nov 7. PMID: 31701464
Article Published Date : Nov 06, 2019
Study Type : Animal Study
Additional Links
Substances : Grape Seed Extract
Diseases : Chemically-Induced Liver Damage
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Proanthocyanidins
Problem Substances : Titanium Dioxide, Titanium Nanoparticles
[+]

Harmine alleviates titanium particle-induced inflammatory bone destruction.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Immunol. 2021 ;12:657687. Epub 2021 May 17. PMID: 34079546
Article Published Date : Dec 31, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Psychedelics:All
Diseases : Inflammation, Titanium Toxicity
Pharmacological Actions : Immunomodulatory
Problem Substances : Titanium Nanoparticles
[+]

N-acetylcysteine protected against titanium dioxide's damaging effects.May 31, 2018

Pubmed Data : Int J Fertil Steril. 2018 Jun ;12(3):249-256. Epub 2018 Jun 20. PMID: 29935072
Article Published Date : May 31, 2018
Study Type : Animal Study
Additional Links
Substances : Cysteine (see N-Acetylcysteine)
Diseases : Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Genoprotective
Problem Substances : Titanium Nanoparticles
[+]

Oral exposure to titanium dioxide nanoparticles for 90 days could disrupt the metabolism of the intestine and gut microbiota.Jun 17, 2020

Pubmed Data : Beijing Da Xue Xue Bao Yi Xue Ban. 2020 Jun 18 ;52(3):457-463. PMID: 32541978
Article Published Date : Jun 17, 2020
Study Type : Animal Study
Additional Links
Diseases : Dysbiosis
Problem Substances : Titanium Nanoparticles
Adverse Pharmacological Actions : Gastrotoxic
[+]

Piperlongumine has the potential to treat osteoclast-related diseases.Mar 04, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2022 Mar 5 ;23(5). Epub 2022 Mar 5. PMID: 35270008
Article Published Date : Mar 04, 2022
Study Type : Animal Study
Additional Links
Substances : Piperlongumine
Diseases : Osteoarthritis, Titanium Toxicity
Pharmacological Actions : NF-kappaB Inhibitor, Osteoprotective
Problem Substances : Titanium Nanoparticles
[+]

Resveratrol reduces the progression of titanium particle-induced osteolysis.Sep 30, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2021 Oct ;22(4):1119. Epub 2021 Aug 4. PMID: 34504573
Article Published Date : Sep 30, 2021
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Resveratrol
Diseases : Titanium Toxicity
Pharmacological Actions : Wnt/β-catenin signaling pathway modulation
Problem Substances : Titanium Nanoparticles
[+]

Thymol effectively protects against nano titanium dioxide-induced hepatotoxicity in rats by its antioxidant properties.Dec 16, 2017

Pubmed Data : Environ Toxicol Pharmacol. 2017 Dec 17 ;58:29-36. Epub 2017 Dec 17. PMID: 29289817
Article Published Date : Dec 16, 2017
Study Type : Animal Study
Additional Links
Substances : Thymol
Diseases : Chemically-Induced Liver Damage
Pharmacological Actions : Hepatoprotective
Problem Substances : Titanium Nanoparticles
[+]

Thymoquinone and avenanthramides have antioxidative and anti-inflammatory effect against the detrimental effect of titanium dioxide naonparticles.Dec 31, 2016

Pubmed Data : Pathol Res Pract. 2017 Jan ;213(1):13-22. Epub 2016 Aug 9. PMID: 27916297
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Oats, Thymoquinone
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
Problem Substances : Titanium Dioxide, Titanium Nanoparticles
[+]

Tinospora cordifolia ameliorated titanium dioxide nanoparticle-induced toxicity.Jan 31, 2021

Pubmed Data : Comp Biochem Physiol C Toxicol Pharmacol. 2021 Feb ;240:108908. Epub 2020 Oct 3. PMID: 33022381
Article Published Date : Jan 31, 2021
Study Type : Animal Study
Additional Links
Substances : Guduchi
Diseases : Titanium Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Interferon Gamma Reducer, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Interleukin-8 downregulation, Nrf2 activation, Postaglandin PGE2 downregulation
Problem Substances : Titanium Dioxide, Titanium Nanoparticles
[+]

Titanium dioxide nanoparticles could change stereological and morphometrical parameters of the seminiferous tubules.Dec 31, 2015

Pubmed Data : Bratisl Lek Listy. 2016 ;117(11):659-664. PMID: 28125892
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Diseases : Infertility: Male, Low Testosterone, Titanium Toxicity
Problem Substances : Titanium Dioxide, Titanium Nanoparticles
[+]

Antioxidant thymoquinone and eugenol alleviate TiO 2 nanoparticle-induced toxicity in human blood cells.Jul 18, 2021

Pubmed Data : Toxicol Mech Methods. 2021 Jul 19:1-11. Epub 2021 Jul 19. PMID: 34219618
Article Published Date : Jul 18, 2021
Study Type : In Vitro Study
Additional Links
Substances : Eugenol, Thymoquinone
Diseases : Titanium Toxicity
Pharmacological Actions : Antioxidants
Problem Substances : Titanium Dioxide, Titanium Nanoparticles
[+]

Carcinogenic effects of titanium dioxide nanoparticles in human gastric epithelial cells in vitro.Aug 22, 2013

Pubmed Data : Biomed Pharmacother. 2013 Aug 23. Epub 2013 Aug 23. PMID: 24051123
Article Published Date : Aug 22, 2013
Study Type : In Vitro Study
Additional Links
Diseases : Gastric Cancer
Anti Therapeutic Actions : Nanotechnology
Problem Substances : Nanoparticles, Titanium Dioxide, Titanium Nanoparticles
Adverse Pharmacological Actions : Carcinogenic
[+]

Chrysin protects against titanium particle-induced osteolysis. Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2022 ;13:793087. Epub 2022 Mar 23. PMID: 35401243
Article Published Date : Dec 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Chrysin
Diseases : Osteoarthritis
Pharmacological Actions : Osteoprotective
Problem Substances : Titanium Nanoparticles
[+]

Inhibitory effect of acetyl-11-keto-β-boswellic acid on titanium particle-induced bone loss.Apr 30, 2021

Pubmed Data : Int Immunopharmacol. 2021 May ;94:107459. Epub 2021 Feb 19. PMID: 33611061
Article Published Date : Apr 30, 2021
Study Type : In Vitro Study
Additional Links
Substances : acetyl-11-keto-beta-boswellic acid
Diseases : Titanium Toxicity
Pharmacological Actions : Osteoprotective
Problem Substances : Titanium Nanoparticles
[+]

Naringin inhibits titanium particles-induced up-regulation of TNF-α and IL-6.Jun 20, 2020

Pubmed Data : Connect Tissue Res. 2020 Jun 21:1-10. Epub 2020 Jun 21. PMID: 32500755
Article Published Date : Jun 20, 2020
Study Type : In Vitro Study
Additional Links
Substances : Citrus naringin
Diseases : Inflammation, Titanium Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Titanium Nanoparticles
[+]

Puerarin inhibits titanium particle-induced osteolysis and RANKL-induced osteoclastogenesis.Sep 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cell Mol Med. 2020 Oct ;24(20):11972-11983. Epub 2020 Sep 7. PMID: 32896108
Article Published Date : Sep 30, 2020
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Titanium Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Titanium Nanoparticles
[+]

Rhoifolin ameliorates titanium particle-stimulated osteolysis and attenuates osteoclastogenesis via RANKL-induced NF-κB and MAPK pathways.Dec 31, 2018

Pubmed Data : J Cell Physiol. 2019 08 ;234(10):17600-17611. Epub 2019 Mar 10. PMID: 30854667
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids
Diseases : Titanium Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor
Problem Substances : Titanium Nanoparticles
[+]

These data support the antioxidant properties' nutraceutical role of Moringa oleifera against titanium dioxide nanoparticles-induced toxicity.May 03, 2018

Pubmed Data : Biol Trace Elem Res. 2018 May 4. Epub 2018 May 4. PMID: 29728821
Article Published Date : May 03, 2018
Study Type : In Vitro Study
Additional Links
Substances : Moringa oleifera
Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Nrf2 activation
Problem Substances : Titanium Dioxide, Titanium Nanoparticles
[+]

TiO2 nanoparticles cause mitochondrial dysfunction, activate inflammatory responses, and attenuate phagocytosis in macrophages.Dec 27, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Redox Biol. 2017 Dec 28 ;15:266-276. Epub 2017 Dec 28. PMID: 29294438
Article Published Date : Dec 27, 2017
Study Type : In Vitro Study
Additional Links
Problem Substances : Titanium Nanoparticles
Adverse Pharmacological Actions : Inflammatory

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Researchers examining 44 samples of 30 different vaccines found dangerous contaminants, including red blood cells in one vaccine and metal toxicants in every single sample tested – except in one animal vaccine.

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