Titanium Nanoparticles

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12 Diseases Researched for Titanium Nanoparticles

Name	AC	CK
Titanium Toxicity	12	19
Chemically-Induced Liver Damage	3	6
Osteoarthritis	3	5
Inflammation	2	3
Bone Diseases	1	2
Dysbiosis	1	2
Infertility: Male	1	2
Kidney Damage: Chemically-Induced	1	2
Low Testosterone	1	2
Oxidative Stress	1	2
Testicular Injury: Chemical/Metal Induced	1	2
Gastric Cancer	1	1

3 Adverse Pharmacological Actions Researched for Titanium Nanoparticles

Name	AC	CK
Gastrotoxic	1	2
Carcinogenic	1	1
Inflammatory	1	1

Research Articles 24
Cumulative Knowledge Score 38
Overall Research Rating GOOD

View the Evidence:
24 Abstracts with Titanium Nanoparticles Research

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Alleviative effect of lactoferrin interventions against the hepatotoxicity induced by titanium dioxide nanoparticles.May 15, 2023

Click here to read the entire abstract

Pubmed Data : Biol Trace Elem Res. 2023 May 16. Epub 2023 May 16. PMID: 37191759

Article Published Date : May 15, 2023

Study Type : Animal Study

Additional Links

Substances : Lactoferrin

Diseases : Chemically-Induced Liver Damage, Titanium Toxicity

Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents, Antioxidants, Hepatoprotective

Problem Substances : Titanium Dioxide, Titanium Nanoparticles

[+]

Aged garlic extract was able to reduce titanium dioxide toxicity in male rats. Aug 21, 2016

Click here to read the entire abstract

Pubmed Data : Andrologia. 2016 Aug 22. Epub 2016 Aug 22. PMID: 27546106

Article Published Date : Aug 21, 2016

Study Type : Animal Study

Additional Links

Substances : Garlic: Aged

Diseases : Oxidative Stress

Pharmacological Actions : Antioxidants

Problem Substances : Titanium Nanoparticles

[+]

Ameliorative effects of thymoquinone on titanium dioxide nanoparticles induced acute toxicity.May 31, 2018

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Vet Sci Med. 2018 Jun ;6(1):16-21. Epub 2018 Feb 23. PMID: 30255073

Article Published Date : May 31, 2018

Study Type : Animal Study

Additional Links

Substances : Thymoquinone

Diseases : Titanium Toxicity

Pharmacological Actions : Antioxidants

Problem Substances : Titanium Dioxide, Titanium Nanoparticles

[+]

Curcumin has immunomodulatory effects on RANKL-stimulated osteoclastogenesis in vitro and titanium nanoparticle-induced bone loss in vivo.Dec 16, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Cell Mol Med. 2019 Dec 17. Epub 2019 Dec 17. PMID: 31845532

Article Published Date : Dec 16, 2019

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Curcumin

Diseases : Bone Diseases, Osteoarthritis

Pharmacological Actions : Osteoprotective

Problem Substances : Titanium Nanoparticles

[+]

Ginkgo biloba extract reverses the renal effects of titanium dioxide nanoparticles in adult male rats.Dec 31, 2015

Click here to read the entire abstract

Pubmed Data : Biochem Res Int. 2016 ;2016:5781579. Epub 2016 Mar 3. PMID: 27042354

Article Published Date : Dec 31, 2015

Study Type : Animal Study

Additional Links

Substances : Ginkgo biloba

Diseases : Kidney Damage: Chemically-Induced

Pharmacological Actions : Renoprotective

Additional Keywords : Plant Extracts

Problem Substances : Titanium Dioxide, Titanium Nanoparticles

[+]

Grape seed proanthocyanidin extract mitigates titanium dioxide nanoparticle-induced hepatotoxicity.Nov 06, 2019

Click here to read the entire abstract

Pubmed Data : Biol Trace Elem Res. 2019 Nov 7. Epub 2019 Nov 7. PMID: 31701464

Article Published Date : Nov 06, 2019

Study Type : Animal Study

Additional Links

Substances : Grape Seed Extract

Diseases : Chemically-Induced Liver Damage

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Proanthocyanidins

Problem Substances : Titanium Dioxide, Titanium Nanoparticles

[+]

Harmine alleviates titanium particle-induced inflammatory bone destruction.Dec 31, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Immunol. 2021 ;12:657687. Epub 2021 May 17. PMID: 34079546

Article Published Date : Dec 31, 2020

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Psychedelics:All

Diseases : Inflammation, Titanium Toxicity

Pharmacological Actions : Immunomodulatory

Problem Substances : Titanium Nanoparticles

[+]

N-acetylcysteine protected against titanium dioxide's damaging effects.May 31, 2018

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Pubmed Data : Int J Fertil Steril. 2018 Jun ;12(3):249-256. Epub 2018 Jun 20. PMID: 29935072

Article Published Date : May 31, 2018

Study Type : Animal Study

Additional Links

Substances : Cysteine (see N-Acetylcysteine)

Diseases : Testicular Injury: Chemical/Metal Induced

Pharmacological Actions : Genoprotective

Problem Substances : Titanium Nanoparticles

[+]

Oral exposure to titanium dioxide nanoparticles for 90 days could disrupt the metabolism of the intestine and gut microbiota.Jun 17, 2020

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Pubmed Data : Beijing Da Xue Xue Bao Yi Xue Ban. 2020 Jun 18 ;52(3):457-463. PMID: 32541978

Article Published Date : Jun 17, 2020

Study Type : Animal Study

Additional Links

Diseases : Dysbiosis

Problem Substances : Titanium Nanoparticles

Adverse Pharmacological Actions : Gastrotoxic

[+]

Piperlongumine has the potential to treat osteoclast-related diseases.Mar 04, 2022

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Mol Sci. 2022 Mar 5 ;23(5). Epub 2022 Mar 5. PMID: 35270008

Article Published Date : Mar 04, 2022

Study Type : Animal Study

Additional Links

Substances : Piperlongumine

Diseases : Osteoarthritis, Titanium Toxicity

Pharmacological Actions : NF-kappaB Inhibitor, Osteoprotective

Problem Substances : Titanium Nanoparticles

[+]

Resveratrol reduces the progression of titanium particle-induced osteolysis.Sep 30, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Exp Ther Med. 2021 Oct ;22(4):1119. Epub 2021 Aug 4. PMID: 34504573

Article Published Date : Sep 30, 2021

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Resveratrol

Diseases : Titanium Toxicity

Pharmacological Actions : Wnt/β-catenin signaling pathway modulation

Problem Substances : Titanium Nanoparticles

[+]

Thymol effectively protects against nano titanium dioxide-induced hepatotoxicity in rats by its antioxidant properties.Dec 16, 2017

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Pubmed Data : Environ Toxicol Pharmacol. 2017 Dec 17 ;58:29-36. Epub 2017 Dec 17. PMID: 29289817

Article Published Date : Dec 16, 2017

Study Type : Animal Study

Additional Links

Substances : Thymol

Diseases : Chemically-Induced Liver Damage

Pharmacological Actions : Hepatoprotective

Problem Substances : Titanium Nanoparticles

[+]

Thymoquinone and avenanthramides have antioxidative and anti-inflammatory effect against the detrimental effect of titanium dioxide naonparticles.Dec 31, 2016

Click here to read the entire abstract

Pubmed Data : Pathol Res Pract. 2017 Jan ;213(1):13-22. Epub 2016 Aug 9. PMID: 27916297

Article Published Date : Dec 31, 2016

Study Type : Animal Study

Additional Links

Substances : Oats, Thymoquinone

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants

Problem Substances : Titanium Dioxide, Titanium Nanoparticles

[+]

Tinospora cordifolia ameliorated titanium dioxide nanoparticle-induced toxicity.Jan 31, 2021

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Pubmed Data : Comp Biochem Physiol C Toxicol Pharmacol. 2021 Feb ;240:108908. Epub 2020 Oct 3. PMID: 33022381

Article Published Date : Jan 31, 2021

Study Type : Animal Study

Additional Links

Substances : Guduchi

Diseases : Titanium Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Interferon Gamma Reducer, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Interleukin-8 downregulation, Nrf2 activation, Postaglandin PGE2 downregulation

Problem Substances : Titanium Dioxide, Titanium Nanoparticles

[+]

Titanium dioxide nanoparticles could change stereological and morphometrical parameters of the seminiferous tubules.Dec 31, 2015

Click here to read the entire abstract

Pubmed Data : Bratisl Lek Listy. 2016 ;117(11):659-664. PMID: 28125892

Article Published Date : Dec 31, 2015

Study Type : Animal Study

Additional Links

Diseases : Infertility: Male, Low Testosterone, Titanium Toxicity

Problem Substances : Titanium Dioxide, Titanium Nanoparticles

[+]

Antioxidant thymoquinone and eugenol alleviate TiO 2 nanoparticle-induced toxicity in human blood cells.Jul 18, 2021

Click here to read the entire abstract

Pubmed Data : Toxicol Mech Methods. 2021 Jul 19:1-11. Epub 2021 Jul 19. PMID: 34219618

Article Published Date : Jul 18, 2021

Study Type : In Vitro Study

Additional Links

Substances : Eugenol, Thymoquinone

Diseases : Titanium Toxicity

Pharmacological Actions : Antioxidants

Problem Substances : Titanium Dioxide, Titanium Nanoparticles

[+]

Carcinogenic effects of titanium dioxide nanoparticles in human gastric epithelial cells in vitro.Aug 22, 2013

Click here to read the entire abstract

Pubmed Data : Biomed Pharmacother. 2013 Aug 23. Epub 2013 Aug 23. PMID: 24051123

Article Published Date : Aug 22, 2013

Study Type : In Vitro Study

Additional Links

Diseases : Gastric Cancer

Anti Therapeutic Actions : Nanotechnology

Problem Substances : Nanoparticles, Titanium Dioxide, Titanium Nanoparticles

Adverse Pharmacological Actions : Carcinogenic

[+]

Chrysin protects against titanium particle-induced osteolysis. Dec 31, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Pharmacol. 2022 ;13:793087. Epub 2022 Mar 23. PMID: 35401243

Article Published Date : Dec 31, 2021

Study Type : In Vitro Study

Additional Links

Substances : Chrysin

Diseases : Osteoarthritis

Pharmacological Actions : Osteoprotective

Problem Substances : Titanium Nanoparticles

[+]

Inhibitory effect of acetyl-11-keto-β-boswellic acid on titanium particle-induced bone loss.Apr 30, 2021

Click here to read the entire abstract

Pubmed Data : Int Immunopharmacol. 2021 May ;94:107459. Epub 2021 Feb 19. PMID: 33611061

Article Published Date : Apr 30, 2021

Study Type : In Vitro Study

Additional Links

Substances : acetyl-11-keto-beta-boswellic acid

Diseases : Titanium Toxicity

Pharmacological Actions : Osteoprotective

Problem Substances : Titanium Nanoparticles

[+]

Naringin inhibits titanium particles-induced up-regulation of TNF-α and IL-6.Jun 20, 2020

Click here to read the entire abstract

Pubmed Data : Connect Tissue Res. 2020 Jun 21:1-10. Epub 2020 Jun 21. PMID: 32500755

Article Published Date : Jun 20, 2020

Study Type : In Vitro Study

Additional Links

Substances : Citrus naringin

Diseases : Inflammation, Titanium Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Problem Substances : Titanium Nanoparticles

[+]

Puerarin inhibits titanium particle-induced osteolysis and RANKL-induced osteoclastogenesis.Sep 30, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Cell Mol Med. 2020 Oct ;24(20):11972-11983. Epub 2020 Sep 7. PMID: 32896108

Article Published Date : Sep 30, 2020

Study Type : In Vitro Study

Additional Links

Substances : Puerarin

Diseases : Titanium Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Problem Substances : Titanium Nanoparticles

[+]

Rhoifolin ameliorates titanium particle-stimulated osteolysis and attenuates osteoclastogenesis via RANKL-induced NF-κB and MAPK pathways.Dec 31, 2018

Click here to read the entire abstract

Pubmed Data : J Cell Physiol. 2019 08 ;234(10):17600-17611. Epub 2019 Mar 10. PMID: 30854667

Article Published Date : Dec 31, 2018

Study Type : In Vitro Study

Additional Links

Substances : Flavonoids

Diseases : Titanium Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor

Problem Substances : Titanium Nanoparticles

[+]

These data support the antioxidant properties' nutraceutical role of Moringa oleifera against titanium dioxide nanoparticles-induced toxicity.May 03, 2018

Click here to read the entire abstract

Pubmed Data : Biol Trace Elem Res. 2018 May 4. Epub 2018 May 4. PMID: 29728821

Article Published Date : May 03, 2018

Study Type : In Vitro Study

Additional Links

Substances : Moringa oleifera

Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Nrf2 activation

Problem Substances : Titanium Dioxide, Titanium Nanoparticles

[+]

TiO2 nanoparticles cause mitochondrial dysfunction, activate inflammatory responses, and attenuate phagocytosis in macrophages.Dec 27, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Redox Biol. 2017 Dec 28 ;15:266-276. Epub 2017 Dec 28. PMID: 29294438

Article Published Date : Dec 27, 2017

Study Type : In Vitro Study

Additional Links

Problem Substances : Titanium Nanoparticles

Adverse Pharmacological Actions : Inflammatory

Research Articles 24
Cumulative Knowledge Score 38
Overall Research Rating GOOD

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Focus Your Research

Click any topic below to filter + focus research

View the Evidence: 24 Abstracts with Titanium Nanoparticles Research

Limited to Members Only

Currently Available Sorting Options

Alleviative effect of lactoferrin interventions against the hepatotoxicity induced by titanium dioxide nanoparticles.May 15, 2023

Aged garlic extract was able to reduce titanium dioxide toxicity in male rats. Aug 21, 2016

Ameliorative effects of thymoquinone on titanium dioxide nanoparticles induced acute toxicity.May 31, 2018

Curcumin has immunomodulatory effects on RANKL-stimulated osteoclastogenesis in vitro and titanium nanoparticle-induced bone loss in vivo.Dec 16, 2019

Ginkgo biloba extract reverses the renal effects of titanium dioxide nanoparticles in adult male rats.Dec 31, 2015

Grape seed proanthocyanidin extract mitigates titanium dioxide nanoparticle-induced hepatotoxicity.Nov 06, 2019

Harmine alleviates titanium particle-induced inflammatory bone destruction.Dec 31, 2020

N-acetylcysteine protected against titanium dioxide's damaging effects.May 31, 2018

Oral exposure to titanium dioxide nanoparticles for 90 days could disrupt the metabolism of the intestine and gut microbiota.Jun 17, 2020

Piperlongumine has the potential to treat osteoclast-related diseases.Mar 04, 2022

Resveratrol reduces the progression of titanium particle-induced osteolysis.Sep 30, 2021

Thymol effectively protects against nano titanium dioxide-induced hepatotoxicity in rats by its antioxidant properties.Dec 16, 2017

Thymoquinone and avenanthramides have antioxidative and anti-inflammatory effect against the detrimental effect of titanium dioxide naonparticles.Dec 31, 2016

Tinospora cordifolia ameliorated titanium dioxide nanoparticle-induced toxicity.Jan 31, 2021

Titanium dioxide nanoparticles could change stereological and morphometrical parameters of the seminiferous tubules.Dec 31, 2015

Antioxidant thymoquinone and eugenol alleviate TiO 2 nanoparticle-induced toxicity in human blood cells.Jul 18, 2021

Carcinogenic effects of titanium dioxide nanoparticles in human gastric epithelial cells in vitro.Aug 22, 2013

Chrysin protects against titanium particle-induced osteolysis. Dec 31, 2021

Inhibitory effect of acetyl-11-keto-β-boswellic acid on titanium particle-induced bone loss.Apr 30, 2021

Naringin inhibits titanium particles-induced up-regulation of TNF-α and IL-6.Jun 20, 2020

Puerarin inhibits titanium particle-induced osteolysis and RANKL-induced osteoclastogenesis.Sep 30, 2020

Rhoifolin ameliorates titanium particle-stimulated osteolysis and attenuates osteoclastogenesis via RANKL-induced NF-κB and MAPK pathways.Dec 31, 2018

These data support the antioxidant properties' nutraceutical role of Moringa oleifera against titanium dioxide nanoparticles-induced toxicity.May 03, 2018

TiO2 nanoparticles cause mitochondrial dysfunction, activate inflammatory responses, and attenuate phagocytosis in macrophages.Dec 27, 2017

Titanium Nanoparticles Related Articles

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Titanium Nanoparticles

View the Evidence:
24 Abstracts with Titanium Nanoparticles Research