Triclosan

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10 Diseases Researched for Triclosan
NameACCKFocus
Hypothyroidism47Locked
Estrogen Dominance12Locked
Hormonal Disorders: Children12Locked
Infants: Low Birth Weight12Locked
Prenatal Chemical Exposures12Locked
Sexual Dysfunction12Locked
Thyroid Diseases12Locked
Autoimmune Thyroiditis11Locked
Detoxification: Impaired11Locked
Hyperthyroidism11Locked
5 Adverse Pharmacological Actions Researched for Triclosan
NameACCKFocus
Endocrine Disruptor: Thyroid24Locked
Thyroid Suppressive24Locked
Cytotoxic12Locked
Genotoxic12Locked
Sulfotransferase inhibitors11Locked

View the Evidence:
45 Abstracts with Triclosan Research

[+]

Association of urinary bisphenols and triclosan with thyroid function during early pregnancy.Jan 11, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Int. 2019 12 ;133(Pt A):105123. Epub 2019 Sep 12. PMID: 31521814
Article Published Date : Jan 11, 2019
Study Type : Human Study
Additional Links
Diseases : Bisphenol Toxicity, Fetal Origin of Adult Disease, Prenatal Chemical Exposures
Additional Keywords : Risk Factors
Problem Substances : Bisphenol A , Bisphenol S, Triclosan
[+]

Internal body concentrations of endocrine disrupting chemicals are associated with an increased risk of subfertility together with alterations in hormone levels.Aug 16, 2015

Pubmed Data : Environ Int. 2015 Aug 17 ;84:154-160. Epub 2015 Aug 17. PMID: 26292060
Article Published Date : Aug 16, 2015
Study Type : Human Study
Additional Links
Diseases : Bisphenol-A Toxicity, Infertility: Male, Phthalate Toxicity
Problem Substances : Bisphenol A , Endocrine Disrupting Chemicals (EDCs), Perfluorinated compounds, Phthalates, Triclosan
Adverse Pharmacological Actions : Anti-Fertility
[+]

Prenatal triclosan exposure was associated with reduced head and abdominal circumference at birth and reduced anogenital distance.Feb 22, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Health Perspect. 2016 Feb 23. Epub 2016 Feb 23. PMID: 26908126
Article Published Date : Feb 22, 2016
Study Type : Human Study
Additional Links
Diseases : Prenatal Chemical Exposures
Problem Substances : Triclosan
[+]

Sunscreen and mouthwash may be important exposure sources for endocrine disrupting compounds.May 10, 2016

Pubmed Data : J Expo Sci Environ Epidemiol. 2016 May 11. Epub 2016 May 11. PMID: 27168391
Article Published Date : May 10, 2016
Study Type : Human Study
Additional Links
Additional Keywords : Mouthwash, Risk Factors
Problem Substances : Benzophenones, Endocrine Disrupting Chemicals (EDCs), Parabens, Phthalates, Sunscreen, Triclosan
[+]

The study provides evidence that exposure to triclosan is associated with poorer semen quality.Dec 06, 2017

Pubmed Data : Environ Sci Pollut Res Int. 2017 Dec 7. Epub 2017 Dec 7. PMID: 29214481
Article Published Date : Dec 06, 2017
Study Type : Human Study
Additional Links
Diseases : Infertility: Male
Problem Substances : Triclosan
[+]

These findings indicate that triclosan exposure might cause spontaneous abortion.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2015 ;5:18252. Epub 2015 Dec 15. PMID: 26666354
Article Published Date : Dec 31, 2014
Study Type : Animal Study, Human Study
Additional Links
Diseases : Abortion: Spontaneous, Miscarriage
Additional Keywords : Risk Factors
Problem Substances : Triclosan
Adverse Pharmacological Actions : Abortive
[+]

These results suggested the potential for triclosan to be associated with increased risk of gestational diabetes mellitus.Jan 15, 2018

Pubmed Data : Sci Total Environ. 2018 Jan 16 ;626:451-457. Epub 2018 Jan 16. PMID: 29353787
Article Published Date : Jan 15, 2018
Study Type : Human Study
Additional Links
Diseases : Gestational Diabetes
Additional Keywords : Risk Factors
Problem Substances : Triclosan
[+]

This study provides the first evidence of associations between antimicrobials and potential adverse birth outcomes in neonates.Mar 10, 2016

Pubmed Data : J Hazard Mater. 2016 Mar 11. Epub 2016 Mar 11. PMID: 27156397
Article Published Date : Mar 10, 2016
Study Type : Human Study
Additional Links
Diseases : Fetal Origin of Adult Disease
Problem Substances : Parabens, Triclosan
Adverse Pharmacological Actions : Anti-Fertility, Neurotoxic
[+]

Triclosan may affect human sperm production and normal morphology.Jan 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Environ Res Public Health. 2016 Feb ;13(2):224. Epub 2016 Feb 17. PMID: 26901211
Article Published Date : Jan 31, 2016
Study Type : Human Study
Additional Links
Diseases : Infertility: Male
Problem Substances : Triclosan
[+]

Triclosan and bisphenol A might alter human endometrium physiology so affecting fertility and pregnancy outcome.Nov 17, 2015

Pubmed Data : Mol Cell Endocrinol. 2015 Nov 18. Epub 2015 Nov 18. PMID: 26604029
Article Published Date : Nov 17, 2015
Study Type : Human In Vitro
Additional Links
Diseases : Bisphenol Toxicity, Infertility
Problem Substances : Bisphenol A , Triclosan
Adverse Pharmacological Actions : Anti-Fertility
[+]

Triclosan and octylphenol may promote breast cancer progression.May 18, 2014

Pubmed Data : Chem Res Toxicol. 2014 May 19 ;27(5):834-42. Epub 2014 Apr 8. PMID: 24684733
Article Published Date : May 18, 2014
Study Type : Human In Vitro
Additional Links
Diseases : Breast Cancer
Additional Keywords : Gene Expression
Problem Substances : Octylphenol , Triclosan
[+]

Triclosan is a mitochondrial uncoupler and may affect numerous cell types and functions.May 31, 2016

Pubmed Data : J Appl Toxicol. 2016 Jun ;36(6):777-89. Epub 2015 Jul 23. PMID: 26204821
Article Published Date : May 31, 2016
Study Type : Human In Vitro, In Vitro Study
Additional Links
Problem Substances : Triclosan
[+]

Acute exposure to triclosan has the potential to cause subtle cardiac toxicity in developing fish.Apr 19, 2016

Pubmed Data : Zebrafish. 2016 Apr 20. Epub 2016 Apr 20. PMID: 27097057
Article Published Date : Apr 19, 2016
Study Type : Animal Study
Additional Links
Problem Substances : Triclosan
Adverse Pharmacological Actions : Cardiotoxic
[+]

Agricultural irrigation presents an additional exposure route for organic contaminants to humans via commercial crops.Apr 30, 2016

Pubmed Data : J Environ Qual. 2016 May ;45(3):1029-35. PMID: 27136171
Article Published Date : Apr 30, 2016
Study Type : Environmental
Additional Links
Additional Keywords : Environmental Pollutant
Problem Substances : Triclosan
[+]

Anthropogenic contaminants of high concern: Existence in water resources and their adverse effects.Nov 09, 2019

Pubmed Data : Sci Total Environ. 2019 Nov 10 ;690:1068-1088. Epub 2019 Jul 6. PMID: 31470472
Article Published Date : Nov 09, 2019
Study Type : Environmental
Additional Links
Additional Keywords : Environmental Fate of Pharmacueticals, Public Drinking Water, Water Pollution
Problem Substances : Acetaminophen, Diclofenac, Ibuprofen, Naproxen, Ofloxacin, Pesticides, Ranitidine, Triclosan
[+]

Biosolids-derived triclocarban and triclosan are present throughout the terrestrial food web.Dec 19, 2016

Pubmed Data : Environ Sci Technol. 2016 Dec 20 ;50(24):13206-13214. Epub 2016 Dec 5. PMID: 27993073
Article Published Date : Dec 19, 2016
Study Type : Environmental
Additional Links
Problem Substances : Biosolids, Triclosan
[+]

Developmental triclosan exposure decreases maternal and neonatal thyroxine in rats.Dec 01, 2010

Pubmed Data : Environ Toxicol Chem. 2010 Dec;29(12):2840-4. Epub 2010 Oct 15. PMID: 20954233
Article Published Date : Dec 01, 2010
Study Type : Animal Study
Additional Links
Diseases : Hypothyroidism, Thyroid Diseases
Problem Substances : Triclosan
Adverse Pharmacological Actions : Endocrine Disruptor: Thyroid, Thyroid Suppressive
[+]

DIM is a potent chemopreventive compound for preventing metastatic behaviours of breast cancer cells induced by endocrine disrupting chemicals.Oct 31, 2017

Pubmed Data : Food Chem Toxicol. 2017 Nov ;109(Pt 1):284-295. Epub 2017 Aug 24. PMID: 28844962
Article Published Date : Oct 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Diseases : Bisphenol Toxicity, Breast Cancer
Pharmacological Actions : Anti-metastatic, Chemopreventive
Problem Substances : Bisphenol A , Triclosan
[+]

Effects of applying biosolids to soils on the adsorption and bioavailability of 17α-ethinylestradiol and triclosan in wheat plants.Mar 31, 2017

Pubmed Data : Environ Sci Pollut Res Int. 2017 Apr 1. Epub 2017 Apr 1. PMID: 28364207
Article Published Date : Mar 31, 2017
Study Type : Environmental
Additional Links
Additional Keywords : Environmental Fate of Pharmacueticals
Problem Substances : Biosolids, Triclosan
[+]

Hormone disruption by triclosan might subsequently affect fetal development and growth.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2016 ;11(5):e0154758. Epub 2016 May 5. PMID: 27149376
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Diseases : Hormone Imbalances
Problem Substances : Triclosan
[+]

Lipid metabolism disorders contribute to hepatotoxicity of triclosan in mice.Sep 23, 2019

Pubmed Data : J Hazard Mater. 2019 Sep 24 ;384:121310. Epub 2019 Sep 24. PMID: 31586915
Article Published Date : Sep 23, 2019
Study Type : Animal Study
Additional Links
Diseases : Chemically-Induced Liver Damage, Liver Disease
Problem Substances : Triclosan
[+]

Maternal exposure to triclosan impairs thyroid homeostasis and female pubertal development in rat offspring.Jan 01, 2010

Pubmed Data : J Toxicol Environ Health A. 2010;73(24):1678-88. PMID: 21058171
Article Published Date : Jan 01, 2010
Study Type : Animal Study
Additional Links
Diseases : Hypothyroidism, Infants: Low Birth Weight, Prenatal Chemical Exposures
Problem Substances : Triclosan
Adverse Pharmacological Actions : Endocrine Disruptor: Thyroid
[+]

Topical triclosan promoted epicutaneous sensitization to both peanut and α-lactalbumin, and promoted anaphylaxis to peanut.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Transl Allergy. 2016 ;6:13. Epub 2016 Apr 5. PMID: 27051518
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Diseases : Food Allergies
Problem Substances : Triclosan
[+]

Triclosan bioconcentrates and exhibits toxicity to amphibian larvae.Aug 01, 2010

Pubmed Data : Comp Biochem Physiol C Toxicol Pharmacol. 2010 Aug;152(2):232-40. Epub 2010 Apr 22. PMID: 20417311
Article Published Date : Aug 01, 2010
Study Type : Animal Study
Additional Links
Problem Substances : Triclosan
Adverse Pharmacological Actions : Cytotoxic
[+]

Triclosan can induce neurodegenerative effects in developing rat brains.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomol Ther (Seoul). 2016 Jan ;24(1):99-107. Epub 2016 Jan 1. PMID: 26759708
Article Published Date : Dec 31, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Additional Keywords : Neural Stem Cells
Problem Substances : Triclosan
Adverse Pharmacological Actions : Neurotoxic
[+]

Triclosan could induce changes in the fetal hypothalamic transcriptomics mainly connected to food intake pathways and metabolism.May 03, 2016

Pubmed Data : Endocrinology. 2016 May 4:en20161080. Epub 2016 May 4. PMID: 27145008
Article Published Date : May 03, 2016
Study Type : Animal Study
Additional Links
Diseases : Fetal Origin of Adult Disease
Additional Keywords : Gene Expression
Problem Substances : Triclosan
[+]

Triclosan exacerbates the presence of bisphenol A in tissues of female and male mice.Jul 14, 2014

Pubmed Data : Toxicol Appl Pharmacol. 2014 Jul 15 ;278(2):116-23. Epub 2014 Apr 29. PMID: 24784443
Article Published Date : Jul 14, 2014
Study Type : Animal Study
Additional Links
Diseases : Bisphenol-A Toxicity
Additional Keywords : Synergistic Toxicity
Problem Substances : Bisphenol A , Triclosan
[+]

Triclosan has selective toxicity for more susceptible microbes when introduced into the soil environment.Aug 31, 2017

Pubmed Data : FEMS Microbiol Lett. 2017 Sep 1 ;364(16). PMID: 28859275
Article Published Date : Aug 31, 2017
Study Type : Environmental
Additional Links
Pharmacological Actions : Environmental Pollutants
Problem Substances : Triclosan
[+]

Triclosan is a mitochondrial uncoupler in live zebrafish.Mar 27, 2016

Pubmed Data : J Appl Toxicol. 2016 Mar 28. Epub 2016 Mar 28. PMID: 27111768
Article Published Date : Mar 27, 2016
Study Type : Animal Study
Additional Links
Problem Substances : Triclosan
[+]

Triclosan is an emergin polluntant with potential biochemical and genetic toxicity in earthworms.Sep 06, 2010

Pubmed Data : Chemosphere. 2010 Sep 6. Epub 2010 Sep 6. PMID: 20825966
Article Published Date : Sep 06, 2010
Study Type : Animal Study
Additional Links
Additional Keywords : Environmental Pollutant
Problem Substances : Triclosan
Adverse Pharmacological Actions : Genotoxic
[+]

Triclosan is an endocrine disruptor which exhibits estrogen disruptive and thyroid suppressive activity in rats.Sep 01, 2010

Pubmed Data : Toxicol Sci. 2010 Sep;117(1):45-53. Epub 2010 Jun 18. PMID: 20562219
Article Published Date : Sep 01, 2010
Study Type : Animal Study
Additional Links
Diseases : Estrogen Dominance, Hormonal Disorders: Children, Hypothyroidism, Sexual Dysfunction
Problem Substances : Triclosan
Adverse Pharmacological Actions : Thyroid Suppressive
[+]

A wide range of environmental polluntants, food additives and pesticides contribute to disrupting thyroid function. Dec 01, 2009

Pubmed Data : Best Pract Res Clin Endocrinol Metab. 2009 Dec;23(6):801-13. PMID: 19942155
Article Published Date : Dec 01, 2009
Study Type : Commentary
Additional Links
Diseases : Autoimmune Thyroiditis, Hyperthyroidism, Hypothyroidism
Problem Substances : Bisphenol A , Perchlorate, Polybrominated diphenylethers (PBDEs), Polychlorinated biphenyls (PCBs), Sodium Nitrate, Thiocyanate, Triclosan
[+]

Early-life exposure to EDCs: role in childhood obesity and neurodevelopment.Nov 17, 2016

Pubmed Data : Nat Rev Endocrinol. 2016 Nov 18. Epub 2016 Nov 18. PMID: 27857130
Article Published Date : Nov 17, 2016
Study Type : Review
Additional Links
Diseases : Neurodevelopmental Disorders, Obesity
Additional Keywords : Risk Factors
Problem Substances : Bisphenol A , Endocrine Disrupting Chemicals (EDCs), Phthalates, Triclosan
[+]

Endocrine disrupting chemicals can increase the risk aggravating the disease for the patients suffering cancer.Dec 28, 2016

Pubmed Data : Mol Cell Endocrinol. 2016 Dec 29. Epub 2016 Dec 29. PMID: 28042023
Article Published Date : Dec 28, 2016
Study Type : In Vitro Study
Additional Links
Diseases : Bisphenol Toxicity, Cancer Metastasis, Cancers: All
Additional Keywords : Risk Factors
Problem Substances : 8-tetrachlorodibenzo-p-dioxin (TCDD), Bisphenol A , Phthalates, Triclosan
[+]

Kaempferol may be suggested as a prominent agent to neutralize breast cancer risk caused by triclosan.Jan 31, 2016

Pubmed Data : J Nutr Biochem. 2016 Feb ;28:70-82. Epub 2015 Oct 23. PMID: 26878784
Article Published Date : Jan 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Kaempferol
Diseases : Breast Cancer
Pharmacological Actions : Antiproliferative , Chemopreventive
Additional Keywords : Risk Reduction
Problem Substances : Triclosan
[+]

Low concentrations of triclosan adversely affected HepG2 cells through DNA methylation dysregulation.Mar 09, 2016

Pubmed Data : Toxicol In Vitro. 2016 Mar 10 ;34:35-44. Epub 2016 Mar 10. PMID: 26970259
Article Published Date : Mar 09, 2016
Study Type : In Vitro Study
Additional Links
Additional Keywords : DNA Methylation, P16 Hypermethylation
Problem Substances : Triclosan
Adverse Pharmacological Actions : Hepatotoxic
[+]

This article reviews human exposure to triclosan and the evidence of its reproductive endocrine-disrupting effects.Oct 31, 2015

Pubmed Data : Environ Pollut. 2015 Nov ;206:195-201. Epub 2015 Jul 13. PMID: 26184583
Article Published Date : Oct 31, 2015
Study Type : Review
Additional Links
Diseases : Infertility
Problem Substances : Triclosan
[+]

Toxic effects of triclosan on a zebrafish liver cell line.Sep 30, 2017

Pubmed Data : Aquat Toxicol. 2017 Oct ;191:175-188. Epub 2017 Aug 19. PMID: 28843737
Article Published Date : Sep 30, 2017
Study Type : In Vitro Study
Additional Links
Diseases : Chemically-Induced Liver Damage
Problem Substances : Triclosan
[+]

Triclosan exerts adverse effects on different biological systems through various modes of action.Dec 31, 2015

Pubmed Data : Annu Rev Pharmacol Toxicol. 2016 ;56:251-72. PMID: 26738475
Article Published Date : Dec 31, 2015
Study Type : Review
Additional Links
Additional Keywords : Environmental Pollutant
Problem Substances : Triclosan
[+]

Triclosan exposure in children has been associated with increased responsiveness to airway allergens.Mar 31, 2016

Pubmed Data : Curr Opin Pediatr. 2016 Apr ;28(2):235-42. PMID: 26867165
Article Published Date : Mar 31, 2016
Study Type : Review
Additional Links
Diseases : Allergic Airway Diseases, Hypersensitivity
Problem Substances : Triclosan
[+]

Triclosan may potentiate cancer cells survival in detached condition and motility via the process of epithelial-to-mesenchymal transition.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2014 ;9(10):e110851. Epub 2014 Oct 16. PMID: 25329306
Article Published Date : Dec 31, 2013
Study Type : In Vitro Study
Additional Links
Diseases : Cancer Metastasis, Lung Cancer
Problem Substances : Triclosan
[+]

Triclosan produces dioxin after undergoing phototransformation.Jun 15, 2010

Pubmed Data : Environ Sci Technol. 2010 Jun 15;44(12):4545-51. PMID: 20476764
Article Published Date : Jun 15, 2010
Study Type : In Vitro Study
Additional Links
Problem Substances : Dioxins, Triclosan
[+]

Triclosan stimulates human vascular endothelial cell injury.Oct 07, 2019

Pubmed Data : Chemosphere. 2019 Oct 8 ;241:125077. Epub 2019 Oct 8. PMID: 31614311
Article Published Date : Oct 07, 2019
Study Type : In Vitro Study
Additional Links
Diseases : Cardiovascular Diseases, Inflammation, Oxidative Stress
Additional Keywords : Risk Factors
Problem Substances : Triclosan
[+]

Triclosan, triclocarban, BDE-47, and BPA was found to inhibit iodide uptake.Mar 31, 2016

Pubmed Data : Toxicol In Vitro. 2016 Apr ;32:310-9. Epub 2016 Jan 29. PMID: 26827900
Article Published Date : Mar 31, 2016
Study Type : In Vitro Study
Additional Links
Problem Substances : Bisphenol A , Triclosan
[+]

Xenobiotics inhibit sulfotransferases responsible for detoxification. Jan 01, 2006

Pubmed Data : Curr Drug Metab. 2006 Jan;7(1):83-104. PMID: 16454694
Article Published Date : Jan 01, 2006
Study Type : Review
Additional Links
Diseases : Detoxification: Impaired
Problem Substances : Bisphenol A , Clomiphene, Danazol, Mefenamic acid, Polychlorinated biphenyls (PCBs), Salicylic acid, Triclosan, Xenobiotics
Adverse Pharmacological Actions : Sulfotransferase inhibitors

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