Vinyl chloride

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8 Diseases Researched for Vinyl chloride

Name	AC	CK
Liver Cancer	4	22
Breast Cancer	2	20
Liver Cirrhosis	1	10
Melanodermia	1	3
DNA damage	1	1
Epithelioid Hemangioendothelioma	1	1
Lung Cancer	1	1
Tumors	1	1

5 Adverse Pharmacological Actions Researched for Vinyl chloride

Name	AC	CK
Carcinogenic	2	11
Tumor Suppressor Protein p53 Down-regulation/Antibody Formation	1	10
Genotoxic	1	1
Mutagenic	1	1
Tumorigenic	1	1

Research Articles 9
Cumulative Knowledge Score 14
Overall Research Rating GOOD

View the Evidence:
9 Abstracts with Vinyl chloride Research

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Anti-p53 (anti-tumor suppressor gene) antibodies in sera of workers occupationally exposed to vinyl chloride.Sep 20, 1995

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Pubmed Data : J Natl Cancer Inst. 1995 Sep 20 ;87(18):1400-7. PMID: 7658501

Article Published Date : Sep 20, 1995

Study Type : Human Study

Additional Links

Diseases : Breast Cancer, Liver Cancer

Additional Keywords : Anti-p53 Antibodies, Tumor Suppressor Genes

Problem Substances : Vinyl chloride

Adverse Pharmacological Actions : Tumor Suppressor Protein p53 Down-regulation/Antibody Formation

[+]

Hazardous air pollutants and breast cancer risk in California teachers: a cohort study.Jan 29, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Environ Health. 2015 Jan 30 ;14(1):14. Epub 2015 Jan 30. PMID: 25636809

Article Published Date : Jan 29, 2015

Study Type : Human Study

Additional Links

Diseases : Breast Cancer

Problem Substances : Acrylamide , Benzene, Vinyl chloride

Adverse Pharmacological Actions : Carcinogenic

[+]

Vinyl chloride exposure is associated with increased risk of liver cancer and liver cirrhosis. Aug 01, 2004

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Pubmed Data : Environ Health Perspect. 2004 Aug;112(11):1188-92. PMID: 15289165

Article Published Date : Aug 01, 2004

Study Type : Human Study

Additional Links

Diseases : Liver Cancer, Liver Cirrhosis

Problem Substances : Vinyl chloride

[+]

Workers exposed to vinyl and polyvinyl chloride have increased tumor rate and mortality. Jan 01, 2008

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Pubmed Data : BMC Public Health. 2008;8:21. Epub 2008 Jan 22. PMID: 18211695

Article Published Date : Jan 01, 2008

Study Type : Human Study

Additional Links

Additional Keywords : Increased Risk

Problem Substances : Polyvinyl chloride, Vinyl chloride

[+]

Toxic vinyl chloride related melanodermia has been reported. Jan 01, 2000

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Pubmed Data : Med Tr Prom Ekol. 2000(4):16-9. PMID: 10870345

Article Published Date : Jan 01, 2000

Study Type : Human: Case Report

Additional Links

Diseases : Melanodermia

Problem Substances : Vinyl chloride

[+]

An organizational approach for the assessment of DNA adduct data in risk assessment: case studies for aflatoxin B1, tamoxifen and vinyl chloride.Mar 31, 2014

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Pubmed Data : Crit Rev Toxicol. 2014 Apr ;44(4):348-91. Epub 2014 Feb 4. PMID: 24494825

Article Published Date : Mar 31, 2014

Study Type : Review

Additional Links

Diseases : DNA damage

Additional Keywords : Drug: Tamoxifen

Problem Substances : Aflatoxin, Tamoxifen, Vinyl chloride

Adverse Pharmacological Actions : Carcinogenic, Genotoxic, Mutagenic

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Breast implants as a possible etiology of epithelioid hemangioendothelioma.Jul 01, 2005

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Pubmed Data : Breast J. 2005 Jul-Aug;11(4):257-61. PMID: 15982392

Article Published Date : Jul 01, 2005

Study Type : Review

Additional Links

Diseases : Epithelioid Hemangioendothelioma, Liver Cancer, Lung Cancer

Problem Substances : Breast Implants, Vinyl chloride

[+]

There are a number of natural and synthetic chemicals with tumor-inducing effects.Oct 01, 2005

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Pubmed Data : Discov Med. 2005 Oct;5(29):472-7. PMID: 20704845

Article Published Date : Oct 01, 2005

Study Type : Commentary

Additional Links

Diseases : Tumors

Problem Substances : Aflatoxin, Aromatic hydrocarbons, Cadmium, Dioxins, Estrogen Receptor Agonists, Lead, N-Nitrosamines, Nickelous acetate, Nickelous Sulfate, Polycyclic aromatic hydrocarbon, Tamoxifen, Vinyl chloride

Adverse Pharmacological Actions : Tumorigenic

[+]

Vinyl chloride is a known cause of liver cancer. Dec 01, 2009

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Pubmed Data : J Hepatol. 2009 Dec;51(6):1074-81. Epub 2009 Oct 1. PMID: 19836850

Article Published Date : Dec 01, 2009

Study Type : Commentary

Additional Links

Diseases : Liver Cancer

Problem Substances : Vinyl chloride

Research Articles 9
Cumulative Knowledge Score 14
Overall Research Rating GOOD

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View evidence that dosages of vinyl chloride as low as 500 ppm may cause appreciable injury when inhaled 7 hours a day, five days a week for an extended period

http://www.chemicalindustryarchives.org/dirtysecrets/vinyl/pdfs/BFG23212001-1.pdf#page=1

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Focus Your Research

Click any topic below to filter + focus research

View the Evidence: 9 Abstracts with Vinyl chloride Research

Limited to Members Only

Currently Available Sorting Options

Anti-p53 (anti-tumor suppressor gene) antibodies in sera of workers occupationally exposed to vinyl chloride.Sep 20, 1995

Hazardous air pollutants and breast cancer risk in California teachers: a cohort study.Jan 29, 2015

Vinyl chloride exposure is associated with increased risk of liver cancer and liver cirrhosis. Aug 01, 2004

Workers exposed to vinyl and polyvinyl chloride have increased tumor rate and mortality. Jan 01, 2008

Toxic vinyl chloride related melanodermia has been reported. Jan 01, 2000

An organizational approach for the assessment of DNA adduct data in risk assessment: case studies for aflatoxin B1, tamoxifen and vinyl chloride.Mar 31, 2014

Breast implants as a possible etiology of epithelioid hemangioendothelioma.Jul 01, 2005

There are a number of natural and synthetic chemicals with tumor-inducing effects.Oct 01, 2005

Vinyl chloride is a known cause of liver cancer. Dec 01, 2009

Vinyl chloride Related Articles

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Vinyl chloride

View the Evidence:
9 Abstracts with Vinyl chloride Research